Perryville, MO

Travel Guide

A train crossing a stone bridge over a river, surrounded by lush greenery.
A forest of tall pine trees at sunset.
A ferry boat on a river with a backdrop of colorful autumn foliage.
Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG

2.5 out of 5
2020 Jefferson St Perryville MO
$101 nightly
The price is $116 total per night from Nov 1 to Nov 2
$116 total
Nov 1 - Nov 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Holiday Inn Express & Suites Perryville by IHG
Days Inn by Wyndham Perryville

Days Inn by Wyndham Perryville

2 out of 5
1500 Liberty Street Perryville MO
$68 nightly
The price is $77 total per night from Nov 1 to Nov 2
$77 total
Nov 1 - Nov 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Perryville Country Club and ...
7/10 Good! (459 reviews)
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Reviewed on Oct 10, 2026

Days Inn by Wyndham Perryville
Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville

2 out of 5
1119 Vincent Dr Perryville MO
$68 nightly
The price is $78 total per night from Nov 8 to Nov 9
$78 total
Nov 8 - Nov 9
Total with taxes and fees
Book a stay at this business-friendly motel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (1,001 reviews)
"Quick and easy check in. Friendly staff."

Reviewed on Oct 9, 2026

Super 8 by Wyndham Perryville
See all 175 properties in Perryville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Urban Lofts

Urban Lofts

3 out of 5
102 N Jackson St Perryville MO
Stay at this aparthotel in Perryville. Enjoy free WiFi, free parking, and dry cleaning or laundry services. Popular attractions Feltz Street Park and Perryville ...
9.4/10 Exceptional! (22 reviews)
"Beautiful, clean property in the heart of city center. Many options for food and shopping within short walking distance."

Reviewed on Jun 11, 2026

Urban Lofts
The Atrium - A Boutique Hotel

The Atrium - A Boutique Hotel

2 out of 5
112 W Ste Maries St Perryville MO
Stay at this aparthotel in Perryville. Enjoy free WiFi, free parking, and bathrobes. Popular attractions Feltz Street Park and Perryville Country Club are located ...
The Atrium - A Boutique Hotel
Hot Tub & Creek Views: Secluded Perryville Cabin

Hot Tub & Creek Views: Secluded Perryville Cabin

Perryville MO
Stay at this cabin in Perryville. Enjoy laundry facilities, patios, and an in-room coffeemaker. Popular attractions County Lake State Wildlife Management Area ...
9.6/10 Exceptional! (15 reviews)
"Wonderful location with the necessities to enjoy your time without taking away from the beauty of where you are"

Reviewed on Sep 26, 2026

Hot Tub & Creek Views: Secluded Perryville Cabin
See all properties in Perryville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Perryville attractions

National Shrine of Our Lady of the Miraculous Medal

8.8/10 (19 reviews)
Find out about the history of Perryville when you take a trip to National Shrine of Our Lady of the Miraculous Medal. Take in the festivals while you're in the area.
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Things to do

Group poses in front of Buffalo Trace Distillery

Private Kentucky Bourbon Trail Tour

$1,846
per adult
Private Kentucky Bourbon Trail Tour
See all activities in Perryville

Frequently asked questions

Is Perryville worth visiting?
Perryville is worth visiting for its significant historical sites, including the National Shrine of Our Lady of the Miraculous Medal and Missouri's National Veterans Memorial. Travelers can also enjoy diverse dining experiences, with options ranging from Italian to North American cuisine.
When is the best time to visit Perryville?
The best time to visit Perryville is from May through September, when the climate is pleasant for outdoor activities. For fewer crowds and better value, the quieter months of November through February are a good option, offering cooler temperatures.
What is Perryville known for?
Perryville is known for the National Shrine of Our Lady of the Miraculous Medal and Missouri's National Veterans Memorial. Travelers can also visit Saint Marys Lake, and the area offers an Italian food culture to explore.
What is a good itinerary length for Perryville?
A good itinerary length for Perryville is one to two days to visit key highlights like the National Shrine of Our Lady of the Miraculous Medal, Missouri's National Veterans Memorial, and Saint Marys Lake. An extended stay of two to three days allows for more relaxed exploration of these sites and time to enjoy the local Italian, North American, or Asian cuisine.
What are the top things to do in and around Perryville?
Perryville offers a mix of historical landmarks, natural beauty, and recreational spots for travelers to enjoy:


How do I plan a trip to Perryville?
To plan your Perryville trip, book flights, rental cars, and places to stay in advance. You can visit attractions like the National Shrine of Our Lady of the Miraculous Medal and Missouri's National Veterans Memorial. For outdoor activities, remember to have indoor backups ready for weather flexibility.
What cuisines can you find in Perryville?
In Perryville, you can find Italian cuisine, with dishes like pasta, pizza, and lasagna. Travelers can also enjoy North American favorites, Chinese specialties such as stir-fries, and Mexican dishes like tacos and burritos. Various coffee shops are available for a casual bite or drink.
Can I book a refundable hotel in Perryville?
Yes, Expedia offers many flexible booking options, and you can look for refundable hotels in Perryville by entering your dates and using the refundable or fully refundable filter. Always check the hotel's cancellation policy before you book, since terms can vary by hotel, and visit Expedia help center for further details.
Why book a trip to Perryville with Expedia?
Expedia makes it easier to plan your Perryville trip with travel tools, flexible search options, and bookable trip components all in one place. You can organize your plans in one account and use Expedia to help build a trip that fits your budget and travel style. Find out more about how by visiting Expedia's Trip Planner page.
Should I stay in a hotel or vacation rental in Perryville?
The best choice depends on your travel style. Hotels in Perryville can be a good fit for convenience, on-site amenities, and shorter stays, while vacation rentals may offer more space, privacy, and home-style amenities for longer trips, families, or groups. With Expedia, you can compare both options side by side, read traveler reviews, and filter by amenities to find the right fit for your trip.
How can I manage my Perryville trip on Expedia?
Once you've booked your Perryville trip, you can manage it through your Expedia account or the Expedia app. You can view your itinerary, access booking details, make eligible changes, and check for updates in My Trips. The Expedia app can also help you stay organized while you travel.
What if I need help during my Perryville trip?
Expedia offers customer support before, during, and after your Perryville trip. If your plans change or something unexpected happens, you can review your booking in My Trips and use Expedia help center channels for help with eligible changes, cancellations, or travel issues.
How can Expedia help me plan my first trip to Perryville?
If it's your first trip to Perryville, Expedia can help you plan by bringing together stays, flights, activities, traveler reviews, and trip-planning tools in one place. With Expedia's Trip Planner you can compare options, read reviews from other travelers, and build an itinerary that matches your interests and budget.
How can I save on my Perryville hotel booking with Expedia?
Join One Key™ for free to unlock instant discounts with Member Prices on select hotels. You can also earn and use OneKeyCash™* on eligible bookings on Expedia. Booking in advance is usually another great way to save on your Perryville hotel.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.

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