A free breakfast buffet, dry cleaning/laundry services, and a gym are just a few of the amenities provided at Hampton Inn Poplar Bluff. Stay connected with free in-room WiFi, and guests can find other amenities such as a business center.
Located in Poplar Bluff, Hampton Inn Poplar Bluff is in a rural area. The area's natural beauty can be seen at Lake Wappapello State Park and Mark Twain National Forest, while Poplar Bluff History Museum and Mo-Ark Regional Railroad Museum are cultural highlights. Visit our Poplar Bluff travel guide
2420 Crestwood Dr, Poplar Bluff, MO, 63901
What's nearby
Lake Wappapello
25 min drive - 20.8 miles
Current River
38 min drive - 38.3 miles
Black River Coliseum
6 min drive - 3.3 miles
Margaret Harwell Art Museum
6 min drive - 3.3 miles
Mo-Ark Regional Railroad Museum
6 min drive - 3.8 miles
Getting around
Poplar Bluff Station
7 min drive
Cape Girardeau, MO (CGI-Cape Girardeau Municipal)
82 min drive
Restaurants
McDonald's
5 min drive
McDonald's
9 min walk
Big Whiskey’s
3 min drive
Starbucks
2 min drive
Sonic Drive-In
4 min drive
About this property
Hampton Inn Poplar Bluff
Hotel in a rural location
Consider a stay at Hampton Inn Poplar Bluff and take advantage of a free breakfast buffet, dry cleaning/laundry services, and a gym. In addition to a business center, guests can connect to free in-room WiFi.
Other perks include:
An indoor pool
Free self parking
Express check-out, express check-in, and an elevator
A front-desk safe, luggage storage, and a 24-hour front desk
Guest reviews speak highly of the breakfast and helpful staff
Room features
All 79 rooms have comforts such as air conditioning, in addition to perks like free WiFi and safes. Guest reviews speak positively of the clean rooms at the property.
More conveniences in all rooms include:
Hypo-allergenic bedding and pillowtop mattresses
Bathrooms with tubs or showers and free toiletries
Yes, this property has an indoor pool. Pool access is from 8 AM–10 PM.
How much does it cost to stay at Hampton Inn Poplar Bluff?
As of Oct 23, 2026, prices found for a 1-night stay for 2 adults at Hampton Inn Poplar Bluff on Nov 8, 2026 start from $101, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.
Is Hampton Inn Poplar Bluff pet-friendly?
Yes, this hotel allows cats and dogs (limit 2 total). There's a fee of USD 50 per accommodation, per stay. Service animals are exempt from fees.
How much is parking?
Self parking is free at this property.
What time is check-in at Hampton Inn Poplar Bluff?
Check-in start time: 3:00 PM; Check-in end time: anytime.
What time is check-out at Hampton Inn Poplar Bluff?
Check-out is at 11:00 AM.
Where is Hampton Inn Poplar Bluff located?
Situated in a rural location, this hotel is 1.2 mi (1.9 km) from Poplar Bluff Regional Medical Center and within 3 mi (5 km) of Poplar Bluff History Museum and North Main Street Historic District. Black River Coliseum and Mo-Ark Regional Railroad Museum are also within 6 mi (10 km).
Can I cancel my reservation for free and receive a full refund?
Yes, this property offers free cancellation on select room rates, because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.
Have a question?
AI iconBetaBeta
Get instant answers with AI powered search of property information and reviews.
Reviews
Hampton Inn Poplar Bluff Reviews
9.4
Exceptional
All reviews shown are from real guest experiences. Only travelers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.More informationOpens in a new window
My granddaughter and I spent the night there so we could go and spend time with my son, our room was very nice the beds were very comfortable, We enjoyed the Hot water, the pool was very nice. breakfast was great, the staff was very friendly, We will be back.
Clean rooms, efficient staff, lovely breakfast. I appreciated the hotel sending a text after I checked in; it made it very easy to get questions answered.
Room was very clean and spacious. Towels were clean, thick and thirsty. Breakfast (included) was good. Bed was comfortable. Hot shower was wonderful. Outdoor walking on and near the property felt safe.
I've stayed here twice now and it met my expectations once again. It's very clean, staff goes above and beyond to make your stay comfortable. Breakfast is wonderful and always hot no matter what time you come down for breakfast. I recommend this hotel highly