Santiago Sur Vacation Rentals from $75: Search Short-Term Rentals

Q: What are some of the best vacation rentals that Santiago Sur has to offer?

Charming 1-Bedroom Beachfront Hotel With Pool : This vacation home rental near Santiago Sur has air-conditioning and WiFi to help you feel perfectly comfortable in your new surroundings.

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Vacation Rentals in Santiago Sur

"Habemos disfrutado mucho la vista de las montanas en fruente del jardin de la casa. Tambien la reserva El Montuosa es preciosa y ofrese muchos senderos, rios y cascadas."

$170 nightly

Jul 16 - Jul 17

Total includes taxes and fees

$285 nightly

Jul 16 - Jul 17

Total includes taxes and fees

$363 nightly

Jul 16 - Jul 17

Total includes taxes and fees

$108 nightly

Jul 26 - Jul 27

Total includes taxes and fees

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Find out more about Santiago Sur

Everything you need to know about Santiago Sur vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santiago Sur vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santiago Sur vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santiago Sur vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santiago Sur. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santiago Sur in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $75 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santiago Sur rentals

At Expedia, we put the best Santiago Sur vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santiago Sur rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santiago Sur vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santiago Sur. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Recent reviews of Santiago Sur properties

5/5 Excellent

"Great location and service."

A verified traveler stayed at Hotel Mykonos Panama

Posted 2 weeks ago

5/5 Excellent

"A wonderful location that was quiet and with a wonderful view. My wife Kelly and I had a delux room that was perfect for us, and our 3 young adult children and friend had a triple, and it was the perfect reunion/graduation location that had something for everyone. Paddleboarding, kayaking and a gorgeous pool to watch surfing. Great launch for Coiba, and birding with Javier was wonderful."

A verified traveler stayed at Hotel Santa Catalina Panama

Posted 2 months ago

Cozy Villa with private pool, 5 min walk to a secluded beach, family friendly

5/5 Excellent

Wonderful place for a getaway

"Great house in the Santa Catalina area, with privacy and an awesome property. The owners were so nice, and they conveniently arranged some horses for us to horseback ride on their property and at the nearby beach, which was fantastic. Great conversation with them as well, they were both very friendly and helpful. The beach was conveniently located, and we were able to walk down to a restaurant 5 minutes away. The pool was also perfect. I wouldn't hesitate to stay here again!"

A verified traveler stayed at Cozy Villa with private pool, 5 min walk to a secluded beach, family friendly

Posted 3 months ago

5/5 Excellent

An unforgettable stay — photos don’t do it justice!

"We stayed here during our trip through Panama and it instantly became one of the highlights of our whole adventure. The property is simply amazing — way more beautiful than we expected, (the photos honestly don’t come close to capturing how special this place really is).The house itself was spotless, super comfortable, and felt like home But what really makes it stand out is the land it’s on — just wow. There’s so much space to wander and it’s surrounded by nature at its best. We saw all kinds of wildlife right on the property and lake. The wild beach nearby made it feel like we had our own private paradise. It’s the kind of place where you can really slow down and reconnect.Brett, the host, was an absolute gem. He greeted us in person when we arrived and was so friendly and welcoming. He gave us loads of great local tips and really made us feel looked after. His team was just as wonderful — everyone we met was kind, helpful, and genuinely seemed happy to be working there. It says a lot about the kind of environment Brett has created, and it added such a nice, relaxed energy to our whole stay.Our kids absolutely adored Brett — our 5-year-old is still talking about him, and our 10-year-old said she wants to come back one day to work with him and help take care of the animals!It’s rare to find a place that feels this genuine, peaceful, and memorable all at once. hank you, Brett (and your amazing team!), for creating such a special place and sharing it with us!"

A verified traveler stayed at North Villa at Lago Bay

Posted 3 months ago

3/5 Okay

Better than reported, not that great though.

"The online 1-star rating is not really justified. Although basic, this place is worth the $55 fee. The Hotels.com experience is to be avoided, they overcharged on the rate. The room was basic, the bed below average, but seeing the many species and number of sea birds in the early morning is a treat. The dirt driveway to the site is a biet of a pain."

A verified traveler stayed at Hotel Hibiscus Garden / Jardin De Papos

Posted 5 months ago

Frequently asked questions

Can I find a vacation rental in Santiago Sur?

Yes, we offer vacation rentals close to well known sights in Santiago Sur, or you can choose a more remote option if you're looking for a relaxing stay.

What are some of the best vacation rentals that Santiago Sur has to offer?

Charming 1-Bedroom Beachfront Hotel With Pool: This vacation home rental near Santiago Sur has air-conditioning and WiFi to help you feel perfectly comfortable in your new surroundings.

What can I see and do in Santiago Sur?

While you're exploring the area, Mariato Beach and Torio Beach are a couple of picturesque spots to get outside and enjoy nature. In the larger area, you’ll find Lagartero Beach and Torio Falls.

What are vacation rentals like in Santiago Sur?

Vacation rentals are private properties you can book for several days or longer in Santiago Sur. Vacation rentals provide amenities like kitchens and laundry facilities so you'll be comfy for your stay. If you're concerned about a sanitized environment, a vacation rental can provide a sense of safety away from public hotel elevators and lobbies bustling with people while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a great option for family trips.

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Santiago Sur Vacation Rentals

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Vacation Rentals in Santiago Sur

Cabin at El Montuoso Reserve.

Accommodation with maximum privacy and comfort

Charming 1-Bedroom Beachfront Hotel With Pool

Kaïsa: Santa Catalina

Find out more about Santiago Sur

Recent reviews of Santiago Sur properties

Hotel Mykonos Panama

Hotel Galería

Hotel Santa Catalina Panama

Kooteja Santa Catalina KAÏSA

Cozy Villa with private pool, 5 min walk to a secluded beach, family friendly

North Villa at Lago Bay

Hotel y Restaurante Mama Ines

Catalina's Hideaway

Hotel Hibiscus Garden / Jardin De Papos

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