Title: Things to Do in Santa Cruz in 2026 | Expedia.com # Things to do in Santa Cruz ## Find and book activities, attractions and tours ## Visit Santa Cruz Types of activities Where to stay [Santa Cruz Travel Guide](https://expedia.com/Santa-Cruz.dx6297178) ![Lake Titicaca which includes general coastal views and a park](https://images.trvl-media.com/place/6053553/c22e3c92-bd89-4998-8279-debb63bcb80e.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Lake Titicaca which includes general coastal views and a park](https://images.trvl-media.com/place/6053553/c22e3c92-bd89-4998-8279-debb63bcb80e.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Lake Titicaca showing general coastal views](https://images.trvl-media.com/place/6053553/d30003cf-36bf-47c4-a856-8f27b62f9d97.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![San Lorenzo Cathedral showing heritage elements, a church or cathedral and heritage architecture](https://images.trvl-media.com/place/6098830/2e73ba4d-fa61-44c6-a724-28b25c241f10.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Strait of Tiquina showing a bay or harbor and a lake or waterhole](https://images.trvl-media.com/place/553248635175056644/70715e48-f239-409a-b288-1f4960b90c59.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ### Santa Cruz Attractions If you're ready to hit the streets of Santa Cruz, sign up for a few of the top [tours & day trips](https://www.expedia.com/things-to-do/en/search?rid=6297178&rfrr=ATG.LP.BodyContent&categories=ToursDayTrips) on offer, and have a friendly guide show you some of the most popular tourist attractions. Offering free cancellations and no added fees, our top {17 fun activities in Santa Cruz [fun activities in Santa Cruz](https://www.expedia.com/things-to-do/en/search?rid=6297178&rfrr=ATG.LP.BodyContent)} are also worth browsing through. --- - ![find price illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__find_price.svg) ### Explore activities Explore thousands of experiences from activities and attractions to day tours and transfer. - ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Book with ease Skip the line- book tickets online in minutes to top attractions with free cancellation on many activities. - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself One Key members save % or more on select activities, hotels, cars and vacation rentals. [Learn about One Key](https://www.expedia.com/welcome-one-key) --- ### Most popular activities in Santa Cruz ### Tours & day trips [See all 17 activities](https://expedia.com/things-to-do/search?&rid=6297178&location=Santa+Cruz&filter.categories=ToursDayTrips) ![Santa Cruz: Wildlife Sanctuary and Preservation Park Tour](https://mediaim.expedia.com/localexpert/48008958/9c1358fb-7943-4ab0-9791-6c054a664529.jpg?impolicy=resizecrop&rw=500&rh=280) ### Santa Cruz: Wildlife Sanctuary and Preservation Park Tour 1d 8.6/10 10 GetYourGuide reviews Free cancellation available $85 includes taxes & fees per adult\* \*Get lower prices by selecting more than 2 adults [](https://www.expedia.com/things-to-do/wildlife-rescue-center-and-preservation-park.a48008958.activity-details?&rid=6297178&location=Santa+Cruz&swp=off) ![Samaipata Fort Tour: Ancient Ruins in 1 Full Day](https://mediaim.expedia.com/localexpert/47039842/7ecefdd0-a146-4d89-9aae-e8e8d23d9dce.jpg?impolicy=resizecrop&rw=500&rh=280) ### Samaipata Fort Tour: Ancient Ruins in 1 Full Day 12h 8/10 1 Viator review Free cancellation available $315 includes taxes & fees per adult\* \*Get lower prices by selecting more than 2 adults [](https://www.expedia.com/things-to-do/tour-el-fuerte-de-samaipata-cuevas-1-full-day.a47039842.activity-details?&rid=6297178&location=Santa+Cruz&swp=off) ![4D/3N Expedition: Che Guevara Route - Disconnect from the World](https://mediaim.expedia.com/localexpert/47090379/4d80936c-4385-44e9-80b9-8e7660c32ae6.jpg?impolicy=resizecrop&rw=500&rh=280) ### 4D/3N Expedition: Che Guevara Route - Disconnect from the World 4d Free cancellation available $799 includes taxes & fees per adult\* \*Get lower prices by selecting more than 2 adults [](https://www.expedia.com/things-to-do/3-day-excursion-on-the-che-guevara-route.a47090379.activity-details?&rid=6297178&location=Santa+Cruz&swp=off) ![3D/2N Getaway on the Che Guevara Route Live the Adventure!](https://mediaim.expedia.com/localexpert/47088323/cdf71877-c1dc-46c6-8af1-3b0ab483f139.jpg?impolicy=resizecrop&rw=500&rh=280) ### 3D/2N Getaway on the Che Guevara Route Live the Adventure! 3d Free cancellation available $699 includes taxes & fees per adult\* \*Get lower prices by selecting more than 2 adults [](https://www.expedia.com/things-to-do/3-day-private-tour-on-ches-route.a47088323.activity-details?&rid=6297178&location=Santa+Cruz&swp=off) ![Private Tour of Santa Cruz: We'll visit the center, Porongo, markets, and t...](https://mediaim.expedia.com/localexpert/52015303/cdc9a922-01de-4add-91e5-d5a8c32d0d92.jpg?impolicy=resizecrop&rw=500&rh=280) ### Private Tour of Santa Cruz: We'll visit the center, Porongo, markets, and t... 4h Free cancellation available $60 includes taxes & fees per adult\* \*Get lower prices by selecting more than 2 adults [](https://www.expedia.com/things-to-do/private-tour-of-santa-cruz-well-visit-the-center-porongo-markets-and-the-river.a52015303.activity-details?&rid=6297178&location=Santa+Cruz&swp=off) ![Jurassic Jungle Hike: Discover the Giant Ferns of Amboró](https://mediaim.expedia.com/localexpert/50731696/bfe771f6-e645-49e6-b440-849ace91d2ba.jpg?impolicy=resizecrop&rw=500&rh=280) ### Jurassic Jungle Hike: Discover the Giant Ferns of Amboró 5h Free cancellation available $162 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/jurassic-jungle-hike-discover-the-giant-ferns-of-amboro.a50731696.activity-details?&rid=6297178&location=Santa+Cruz&swp=off) ![The Condor’s Trail & Hidden Waterfall Adventure](https://mediaim.expedia.com/localexpert/50670935/b0c2f0e8-b5fc-4a5b-8359-5da452b915e3.jpg?impolicy=resizecrop&rw=500&rh=280) ### The Condor’s Trail & Hidden Waterfall Adventure 12h Free cancellation available $162 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/the-condors-trail-hidden-waterfall-adventure.a50670935.activity-details?&rid=6297178&location=Santa+Cruz&swp=off) ![Andes Adventure: El Codo De Los Andes Hike with Transport](https://mediaim.expedia.com/localexpert/50870898/1b45f61c-fede-4646-924c-309632c64708.jpg?impolicy=resizecrop&rw=500&rh=280) ### Andes Adventure: El Codo De Los Andes Hike with Transport 8h 30m Free cancellation available $150 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/andes-adventure-el-codo-de-los-andes-hike-with-transport.a50870898.activity-details?&rid=6297178&location=Santa+Cruz&swp=off) ![2D/1N Getaway: Che Route - Historical Trekking and Nature](https://mediaim.expedia.com/localexpert/44759911/41610ec7-8bd0-4763-8c41-8e525a6dbfcc.jpg?impolicy=resizecrop&rw=500&rh=280) ### 2D/1N Getaway: Che Route - Historical Trekking and Nature 2d Free cancellation available $399 includes taxes & fees per adult\* \*Get lower prices by selecting more than 2 adults [](https://www.expedia.com/things-to-do/2-day-tour-on-the-che-guevara-route-in-bolivia.a44759911.activity-details?&rid=6297178&location=Santa+Cruz&swp=off) ![Bolivia: Bolivian Wine Tasting with Charcuterie Board](https://mediaim.expedia.com/localexpert/51963127/6b80893d-639f-4105-8448-8fe56a73f3bc.jpg?impolicy=resizecrop&rw=500&rh=280) ### Bolivia: Bolivian Wine Tasting with Charcuterie Board 2h Free cancellation available $49 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/bolivia-bolivian-wine-tasting-with-charcuterie-board.a51963127.activity-details?&rid=6297178&location=Santa+Cruz&swp=off) ### Food, drink & nightlife [See all 3 activities](https://expedia.com/things-to-do/search?&rid=6297178&location=Santa+Cruz&filter.categories=FoodDrinkNightlife) ![Private Tour of Santa Cruz: We'll visit the center, Porongo, markets, and t...](https://mediaim.expedia.com/localexpert/52015303/cdc9a922-01de-4add-91e5-d5a8c32d0d92.jpg?impolicy=resizecrop&rw=500&rh=280) ### Private Tour of Santa Cruz: We'll visit the center, Porongo, markets, and t... 4h Free cancellation available $60 includes taxes & fees per adult\* \*Get lower prices by selecting more than 2 adults [](https://www.expedia.com/things-to-do/private-tour-of-santa-cruz-well-visit-the-center-porongo-markets-and-the-river.a52015303.activity-details?&rid=6297178&location=Santa+Cruz&swp=off) ![Bolivia: Bolivian Wine Tasting with Charcuterie Board](https://mediaim.expedia.com/localexpert/51963127/6b80893d-639f-4105-8448-8fe56a73f3bc.jpg?impolicy=resizecrop&rw=500&rh=280) ### Bolivia: Bolivian Wine Tasting with Charcuterie Board 2h Free cancellation available $49 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/bolivia-bolivian-wine-tasting-with-charcuterie-board.a51963127.activity-details?&rid=6297178&location=Santa+Cruz&swp=off) ![Sky-High Sips: Vinos 1750 Wine Tour](https://mediaim.expedia.com/localexpert/50664293/86f6875f-d1d3-4a27-a10e-60f9113a743d.jpg?impolicy=resizecrop&rw=500&rh=280) ### Sky-High Sips: Vinos 1750 Wine Tour 4h Free cancellation available $110 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/sky-high-sips-vinos-1750-wine-tour.a50664293.activity-details?&rid=6297178&location=Santa+Cruz&swp=off) ### Private & custom tours [See all 3 activities](https://expedia.com/things-to-do/search?&rid=6297178&location=Santa+Cruz&filter.categories=Privatecustomtours) ![3D/2N Getaway on the Che Guevara Route Live the Adventure!](https://mediaim.expedia.com/localexpert/47088323/cdf71877-c1dc-46c6-8af1-3b0ab483f139.jpg?impolicy=resizecrop&rw=500&rh=280) ### 3D/2N Getaway on the Che Guevara Route Live the Adventure! 3d Free cancellation available $699 includes taxes & fees per adult\* \*Get lower prices by selecting more than 2 adults [](https://www.expedia.com/things-to-do/3-day-private-tour-on-ches-route.a47088323.activity-details?&rid=6297178&location=Santa+Cruz&swp=off) ![Private Tour of Santa Cruz: We'll visit the center, Porongo, markets, and t...](https://mediaim.expedia.com/localexpert/52015303/cdc9a922-01de-4add-91e5-d5a8c32d0d92.jpg?impolicy=resizecrop&rw=500&rh=280) ### Private Tour of Santa Cruz: We'll visit the center, Porongo, markets, and t... 4h Free cancellation available $60 includes taxes & fees per adult\* \*Get lower prices by selecting more than 2 adults [](https://www.expedia.com/things-to-do/private-tour-of-santa-cruz-well-visit-the-center-porongo-markets-and-the-river.a52015303.activity-details?&rid=6297178&location=Santa+Cruz&swp=off) ![Day Tour / Amboro National Park (north side)](https://mediaim.expedia.com/localexpert/51694818/3bd332a3-870f-4f7d-8241-fd51a1f9cd4d.jpg?impolicy=resizecrop&rw=500&rh=280) ### Day Tour / Amboro National Park (north side) 10h Free cancellation available $139 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/day-tour-amboro-national-park-north-side.a51694818.activity-details?&rid=6297178&location=Santa+Cruz&swp=off) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=ACTIVITIES_SPRING_PROMO_6297178) ## What to do in Santa Cruz - With kids ### Things to Do in Santa Cruz with Kids Santa Cruz boasts loads of close by fun activities for you and your kids. Our [family friendly experiences](https://www.expedia.com/things-to-do/en/search?rid=6297178&rfrr=ATG.LP.BodyContent&categories=Family%20Friendly) will keep the crew entertained for days. --- Looking for sports, concerts, or theater events in Santa Cruz? [Search event tickets](https://www.expedia.com/event-tickets/) to see what's happening today, or to plan what to do this weekend! --- --- ### Discover the most popular places to visit in Santa Cruz ![Plaza 24 de Septiembre which includes heritage architecture and heritage elements as well as a large group of people](https://images.trvl-media.com/place/6098828/2cbd296e-1bf4-483c-835b-4827ab9257d1.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Plaza 24 de Septiembre 4.5/5(26 reviews) The heart of Santa Cruz lies in this public square, where locals relax and tourists sightsee in a welcoming, laid-back atmosphere. [](https://expedia.com/Plaza-24-De-Septiembre-Santa-Cruz.d6098828.Vacation-Attraction) ![San Lorenzo Cathedral which includes heritage elements, heritage architecture and a church or cathedral](https://images.trvl-media.com/place/6098830/07633da9-6b86-46e4-8a7c-5cc7962f1701.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### San Lorenzo Cathedral 4.5/5(15 reviews) One of the most iconic landmarks in Santa Cruz is the city’s mighty cathedral, which houses a museum displaying important artwork. [](https://expedia.com/San-Lorenzo-Cathedral-Santa-Cruz.d6098830.Vacation-Attraction) #### Ventura Mall 4.5/5(28 reviews) During your visit to Santa Cruz, you can find the perfect gifts to bring home at Ventura Mall. Make some time to visit the cathedral while you're in the area. [](https://expedia.com/Ventura-Mall-Santa-Cruz.d553248634697753452.Vacation-Attraction) #### Guembe Biocenter 4.5/5(8 reviews) Explore the great outdoors at Guembe Biocenter, a lovely green space in Colinas del Urubo. While in the area, you can find time to visit its shops. [](https://expedia.com/Guembe-Biocenter-Santa-Cruz.d553248621532465358.Vacation-Attraction) #### Ramon Tahuichi Aguilera Stadium 3/5(1 review) Catch an event at Ramon Tahuichi Aguilera Stadium during your trip to Santa Cruz. While in the area, you can find time to visit its shops. [](https://expedia.com/Ramon-Tahuichi-Aguilera-Stadium-Santa-Cruz.d6098832.Vacation-Attraction) #### Cine Center 4/5(9 reviews) You can get tickets for a performance at Cine Center during your trip to Santa Cruz. While in the area, you can find time to visit its shops. [](https://expedia.com/Cine-Center-Santa-Cruz.d6126769.Vacation-Attraction) #### Santa Cruz Zoo 4/5(9 reviews) Why not visit the native and exotic animals who call Santa Cruz Zoo home during your vacation in Santa Cruz? While in the area, you can find time to visit its shops. [](https://expedia.com/Santa-Cruz-Zoo-Santa-Cruz.d6098836.Vacation-Attraction) #### Lomas de Arena Regional Park 3.5/5(3 reviews) Explore the great outdoors at Lomas de Arena Regional Park, a lovely green space in Santa Cruz. While in the area, you can find time to visit its shops. [](https://expedia.com/Lomas-De-Arena-Regional-Park-Santa-Cruz.d553248621563217780.Vacation-Attraction) #### Plaza Principal San Jose de Chiquitos Learn about the local history of San Jose de Chiquitos when you spend time at Plaza Principal San Jose de Chiquitos. Amble around the area's forest or visit its churches. [](https://expedia.com/Plaza-Principal-San-Jose-De-Chiquitos-San-Jose-de-Chiquitos.d553248621566661478.Vacation-Attraction) ### Discover the most popular landmarks and neighborhoods in Santa Cruz ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Hamacas While Hamacas isn't home to many top sights, Santa Cruz Zoo and Las Brisas Shopping Center are some notable places to visit nearby. [](https://expedia.com/Santa-Cruz-Hamacas.dx553248635975875143) --- Looking for fun things to do nearby? Check [things to do near me](https://www.expedia.com/things-to-do-near-me) to find and book the best things to do, fun activities, and top attractions wherever you happen to be. --- ## Popular day trips from Santa Cruz ![Butterflies in their natural environment in the Pantanal, Brazil.](https://images.trvl-media.com/place/873/ee7eccab-da4c-4a89-888b-37454a3d9c51.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Corumba ![San Lorenzo Cathedral showing a garden](https://images.trvl-media.com/place/6098830/62a42b3d-1dbd-4a81-8566-cea655ebca33.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Santa Cruz ![Arvores na margem do Rio Paraguai no Pantanal. Caceres. Mato Grosso.](https://images.trvl-media.com/place/6157460/e9dae5e0-d485-48d4-a415-841c3aa91e02.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Caceres ![Mountain view in Samaipata, Florida Province of the Santa Cruz Department, Bolivia](https://images.trvl-media.com/place/6200976/99855abd-1497-49bc-91a5-ef76c4e902cb.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Samaipata ![Jesuit Mission wall paintings in San Jose de Chiquitos, Bolivia](https://images.trvl-media.com/place/6344854/c34a2d19-1f8b-4361-810e-e1669bf071f5.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### San Jose de Chiquitos ![Aerial panorama of the city of Santa Cruz de La Sierra in Bolivia](https://images.trvl-media.com/place/6053940/061a3d44-8d8d-42c0-bbec-5d50aec6eab9.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### La Guardia ![One of the UNESCO sites in Bolivia. Distinguished by a unique fusion of European and Amerindian cultural influences, the missions were founded as reductions or reducciones de indios by Jesuits in the 17th and 18th centuries to convert local tribes to Christianity](https://images.trvl-media.com/place/6350629/a7bda61c-df1c-47bf-8f92-5aa2a3e65f6f.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### San Javier ![Portrait of a Tobas warrior during carnival called The Devil Dance (La Diablada), Oruro, Bolivia](https://images.trvl-media.com/place/6352296/feec42f5-cbd9-4576-97cc-129e51391796.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Warnes ## Frequently asked questions ### What can you do in Santa Cruz for free? > - Plaza 24 de Septiembre > - Cine Center > - Ventura Mall > - Kaa-Iya National Park ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app