Title: Visit La Guardia: 2026 Travel Guide for La Guardia, Santa Cruz | Expedia.com [Hotels in La Guardia](https://expedia.com/La-Guardia-Hotels.d6347124.Travel-Guide-Hotels)[Vacation Rentals in La Guardia](https://expedia.com/La-Guardia-Vacation-Rentals.d6347124.Travel-Guide-VacationRentals)[Flights to La Guardia](https://expedia.com/Cheap-Flights-To-La-Guardia.d6347124.Travel-Guide-Flights)[Car Rentals in La Guardia](https://expedia.com/Car-Rentals-In-La-Guardia.d6347124.Car-Rental-Guide)[La Guardia Vacation Packages](https://expedia.com/La-Guardia.d6347124.Destination-Travel-Guides) # La Guardia ## Travel Guide ![Aerial panorama of the city of Santa Cruz de La Sierra in Bolivia](https://images.trvl-media.com/place/6053940/061a3d44-8d8d-42c0-bbec-5d50aec6eab9.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Aerial panorama of the city of Santa Cruz de La Sierra in Bolivia](https://images.trvl-media.com/place/6053940/061a3d44-8d8d-42c0-bbec-5d50aec6eab9.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Vallegrande. Vallegrande is a municipality and small city of Bolivia, capital of the province of Vallegrande in the department of Santa Cruz.](https://images.trvl-media.com/place/553248635975750836/ed3d0a4c-6975-4c77-803a-cec98f6a8b9e.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Jesuit Missions of Chiquitos, Santa Cruz department, Bolivia](https://images.trvl-media.com/place/6347124/1b9e797c-fe9e-4024-be45-ceef93b39e79.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit La Guardia ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=DX_SPRING_PROMO_6347124) - La Guardia Hotel Deals - Vacation Rentals in La Guardia ![Ibis Santa Cruz DE LA Sierra](https://images.trvl-media.com/lodging/88000000/87140000/87138700/87138613/53c67151_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Ibis Santa Cruz DE LA Sierra AVENIDA CRISTOBAL DE MENDOZA Santa Cruz $49 nightly $49 total Mar 1 - Mar 2 Book a stay at this business-friendly hotel in Santa Cruz. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ... 9.6/10 Exceptional! (91 reviews) Great value Reviewed on Feb 21, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F1%2F2026&endDate=3%2F2%2F2026&selected=87138613&PinnedHotelID=87138613&HadPinnedHotel=true®ionId=6347124) ![Camino Real Hotel](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/e96a8418_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Camino Real Hotel Av. San Martín y 4to. Anillo Santa Cruz Fully refundable $117 nightly $117 total Mar 6 - Mar 7 Book a stay at this luxury hotel in Santa Cruz. Enjoy free breakfast, a full-service spa, and 2 bars/lounges. Popular attractions Ventura Mall and Santa Cruz ... 9/10 Wonderful! (420 reviews) Spotless, large and comfortable room was well maintained. Friendly and helpful staff. Delicious breakfast buffet. Location is near excellent shopping and dining options. Reviewed on Feb 5, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F6%2F2026&endDate=3%2F7%2F2026&selected=444475&PinnedHotelID=444475&HadPinnedHotel=true®ionId=6347124) ![Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/bb34bb1f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel Ave. San Martin, #455 Santa Cruz $131 nightly $131 total Mar 29 - Mar 30 Book a stay at this spa hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ... 9/10 Wonderful! (362 reviews) Lovely staff. Great buffets. Reviewed on Feb 23, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F29%2F2026&endDate=3%2F30%2F2026&selected=18758&PinnedHotelID=18758&HadPinnedHotel=true®ionId=6347124) [See all 289 properties in La Guardia](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=2%2F28%2F2026&endDate=3%2F1%2F2026®ionId=6347124) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Premium Suites Deluxe Aparthotel Equipetrol](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/12ef5e8d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Premium Suites Deluxe Aparthotel Equipetrol Calle Las Azucenas No. 127 Santa Cruz Santa Cruz Book a stay at this business-friendly aparthotel in Santa Cruz. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Patio Design LifeStyle ... 9/10 Wonderful! (86 reviews) Clean rooms, friendly people who work there. Parking always a plus Reviewed on Feb 19, 2026 [](https://expedia.com/Santa-Cruz-Hotels-Premium-Suites-Deluxe-Aparthotel-Equipetrol.h24404225.Hotel-Information) ![Apart Hotel Premium Suites Santa Cruz](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/e5844260_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Apart Hotel Premium Suites Santa Cruz Calle Las Begonias Nro 45 Santa Cruz Book a stay at this business-friendly apartment in Santa Cruz. Enjoy free WiFi, free parking, and room service. Popular attractions Patio Design LifeStyle Center ... 8.6/10 Excellent! (99 reviews) Yes, staff were very friendly Reviewed on Dec 29, 2025 [](https://expedia.com/Santa-Cruz-Hotels-Apart-Hotel-Premium-Suites-Santa-Cruz.h5928237.Hotel-Information) ![Equipetrol Suites Apart Hotel](https://images.trvl-media.com/lodging/91000000/90600000/90599400/90599395/2b6207d2_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Equipetrol Suites Apart Hotel Equipetrol Santa Cruz Departamento de Santa Cruz Book a stay at this business-friendly aparthotel in Santa Cruz. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Popular attractions Cine Center and ... [](https://expedia.com/Santa-Cruz-Hotels-Equipetrol-Suites-Apart-Hotel.h90599395.Hotel-Information) [See all properties in La Guardia](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=6347124&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check La Guardia hotel availability [Tonight ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6347124&startDate=2026-02-27&endDate=2026-02-28)[Feb 27 - Feb 28](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6347124&startDate=2026-02-27&endDate=2026-02-28) [Tomorrow night ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6347124&startDate=2026-02-28&endDate=2026-03-01)[Feb 28 - Mar 1](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6347124&startDate=2026-02-28&endDate=2026-03-01) [This weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6347124&startDate=2%2F27%2F2026&endDate=3%2F1%2F2026)[Feb 27 - Mar 1](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6347124&startDate=2%2F27%2F2026&endDate=3%2F1%2F2026) ## Cities near La Guardia ![San Lorenzo Cathedral showing a garden](https://images.trvl-media.com/place/6098830/62a42b3d-1dbd-4a81-8566-cea655ebca33.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Santa Cruz ![Portrait of a Tobas warrior during carnival called The Devil Dance (La Diablada), Oruro, Bolivia](https://images.trvl-media.com/place/6352296/feec42f5-cbd9-4576-97cc-129e51391796.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Warnes ## Explore a world of travel with Expedia - 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Airport (SRE) to Santa Cruz (SRZ) ](https://www.expedia.com/lp/flights/sre/srz/sucre-to-santa-cruz) - [Visit El Torno ](https://www.expedia.com/El-Torno.dx3000419675) - [Guembe Biocenter ](https://www.expedia.com/Guembe-Biocenter-Santa-Cruz.d553248621532465358.Vacation-Attraction) - [Lomas de Arena Regional Park ](https://www.expedia.com/Lomas-De-Arena-Regional-Park-Santa-Cruz.d553248621563217780.Vacation-Attraction) - [Visit Colinas del Urubo ](https://www.expedia.com/Colinas-Del-Urubo.dx6349680) - [Colinas del Urubo Vacations ](https://www.expedia.com/Colinas-Del-Urubo.d6349680.Destination-Travel-Guides) - [Ramon Tahuichi Aguilera Stadium ](https://www.expedia.com/Ramon-Tahuichi-Aguilera-Stadium-Santa-Cruz.d6098832.Vacation-Attraction) - [Cine Center ](https://www.expedia.com/Cine-Center-Santa-Cruz.d6126769.Vacation-Attraction) - [Artecampo ](https://www.expedia.com/Artecampo-Santa-Cruz.d553248621532371681.Vacation-Attraction) - [Car rentals near Colinas del Urubo ](https://www.expedia.com/Car-Rentals-In-Colinas-Del-Urubo.d6349680.Car-Rental-Guide) - [Colinas del Urubo Vacation Rentals ](https://www.expedia.com/Colinas-Del-Urubo-Vacation-Rentals.d6349680.Travel-Guide-VacationRentals) - Cities near La Guardia - Places of interest [Santa Cruz](https://expedia.com/Santa-Cruz.dx6053940)[Colinas del Urubo](https://expedia.com/Colinas-Del-Urubo.dx6349680)[La Belgica](https://expedia.com/La-Belgica.dx6350205)[Cuevas](https://expedia.com/Cuevas.dx6350209)[Warnes](https://expedia.com/Warnes.dx6352296)[El Torno](https://expedia.com/El-Torno.dx3000419675) - [Ventura Mall ](https://expedia.com/Ventura-Mall-Santa-Cruz.d553248634697753452.Vacation-Attraction) - [Plaza 24 de Septiembre ](https://expedia.com/Plaza-24-De-Septiembre-Santa-Cruz.d6098828.Vacation-Attraction) - [Guembe Biocenter ](https://expedia.com/Guembe-Biocenter-Santa-Cruz.d553248621532465358.Vacation-Attraction) - [Ramon Tahuichi Aguilera Stadium ](https://expedia.com/Ramon-Tahuichi-Aguilera-Stadium-Santa-Cruz.d6098832.Vacation-Attraction) - [Amboró National Park ](https://expedia.com/Amboro-National-Park-Santa-Cruz.d6098839.Vacation-Attraction) - [San Lorenzo Cathedral ](https://expedia.com/San-Lorenzo-Cathedral-Santa-Cruz.d6098830.Vacation-Attraction) - [Cine Center ](https://expedia.com/Cine-Center-Santa-Cruz.d6126769.Vacation-Attraction) - [Santa Cruz Zoo ](https://expedia.com/Santa-Cruz-Zoo-Santa-Cruz.d6098836.Vacation-Attraction) - [Blacutt Square ](https://expedia.com/Blacutt-Square-Santa-Cruz.d6126767.Vacation-Attraction) - [Artecampo ](https://expedia.com/Artecampo-Santa-Cruz.d553248621532371681.Vacation-Attraction) - [Lomas de Arena Regional Park ](https://expedia.com/Lomas-De-Arena-Regional-Park-Santa-Cruz.d553248621563217780.Vacation-Attraction) - [Municipal Botanical Garden of Santa Cruz ](https://expedia.com/Municipal-Botanical-Garden-Of-Santa-Cruz-Santa-Cruz.d553248635951339810.Vacation-Attraction) - [La Recova Artisan Walk ](https://expedia.com/La-Recova-Artisan-Walk-Santa-Cruz.d553248621532371683.Vacation-Attraction) - [Las Brisas Shopping Center ](https://expedia.com/Las-Brisas-Shopping-Center-Santa-Cruz.d553248635949096660.Vacation-Attraction) - [Ethno-folkloric Museum ](https://expedia.com/Ethno-Folkloric-Museum-Santa-Cruz.d6098834.Vacation-Attraction) - [Guarani Nandereko Nomai Art and Culture Center ](https://expedia.com/Guarani-Nandereko-Nomai-Art-And-Culture-Center-Santa-Cruz.d553248621532371685.Vacation-Attraction) - [Catedral de Santa Cruz ](https://expedia.com/Catedral-De-Santa-Cruz-Santa-Cruz.d553248621532465359.Vacation-Attraction) - [Sacred Art Museum ](https://expedia.com/Sacred-Art-Museum-Santa-Cruz.d553248621563217782.Vacation-Attraction) - [Arenal Park ](https://expedia.com/Arenal-Park-Santa-Cruz.d553248621563217785.Vacation-Attraction) - [Franco Aleman Cultural Center ](https://expedia.com/Franco-Aleman-Cultural-Center-Santa-Cruz.d553248621532371069.Vacation-Attraction) - [Patio Design LifeStyle Center ](https://expedia.com/Patio-Design-LifeStyle-Center-Santa-Cruz.d916427946376515584.Vacation-Attraction) - [Parque Ecológico ](https://expedia.com/Parque-Ecologico-Santa-Cruz.d916256542859411456.Vacation-Attraction) - [Las Cuevas ](https://expedia.com/Las-Cuevas-Santa-Cruz.d553248621532375532.Vacation-Attraction) - [Univalle ](https://expedia.com/Univalle-Santa-Cruz.d904138417051369472.Vacation-Attraction)