$740 Cheap Brussels Airlines flights Cleveland (CLE) to Samos (SMI)

You'll discover affordable round-trip Brussels Airlines flights from $1,243 from CLE to SMI by sorting your results from "Price (lowest to highest)" on Expedia. Or look for bargains from $740 for a one-way journey.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Getting the best Brussels Airlines deals from CLE to SMI often comes down to booking at the right time. You can save 17% on international flights when you book 18 to 29 days before takeoff instead of four to five months ahead. As an added bonus, you can pocket 17% on average by buying your tickets on a Sunday rather than a Friday, which is often the most expensive day to book.* It's smart to kick off your flight search about one month before you want to travel.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Filter your results by "Morning" and "Early Morning" to browse the earliest flights from CLE to SMI. Leaving early means you're less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.

A rewarding loyalty program and the chance to rack up points through Miles and More are the start of the reasons to leave from CLE to SMI with Brussels Airlines. Plus, when you join our One Key™ program, you can receive OneKeyCash™* alongside Brussels Airlines's loyalty program earnings. You can put it toward your future trips.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.