$432 Cheap Flights from Rome (FCO) to Panama City (PTY)

View $432 flight on Tue, Aug 26, 2025Opens in a new window

Popular airlines from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Tocumen Intl. Airport (PTY)

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Cheap Flights from Rome to Panama City (FCO-PTY)

Prices were available within the past 7 days and start at $432 for one-way flights and $697 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Air Europa
Fri, Sep 5 - Mon, Sep 22
FCO
Rome
PTY
Panama City
$697 Roundtrip, found 4 days ago
$697
Roundtrip
found 4 days ago
Select Air Europa flight, departing Fri, Sep 5 from Rome to Panama City, returning Mon, Sep 22, priced at $697 found 4 days ago
Air Europa
Wed, Sep 17 - Sat, Sep 27
FCO
Rome
PTY
Panama City
$708 Roundtrip, found 4 days ago
$708
Roundtrip
found 4 days ago
Select Air Europa flight, departing Wed, Sep 17 from Rome to Panama City, returning Sat, Sep 27, priced at $708 found 4 days ago
Turkish Airlines
Fri, Aug 29 - Wed, Sep 17
FCO
Rome
PTY
Panama City
$708 Roundtrip, found 4 days ago
$708
Roundtrip
found 4 days ago
Select Turkish Airlines flight, departing Fri, Aug 29 from Rome to Panama City, returning Wed, Sep 17, priced at $708 found 4 days ago
Condor
Sun, Sep 7 - Mon, Sep 15
FCO
Rome
PTY
Panama City
$730 Roundtrip, found 1 day ago
$730
Roundtrip
found 1 day ago
Select Condor flight, departing Sun, Sep 7 from Rome to Panama City, returning Mon, Sep 15, priced at $730 found 1 day ago
Air Europa
Thu, Apr 30 - Wed, May 13
FCO
Rome
PTY
Panama City
$731 Roundtrip, found 4 days ago
$731
Roundtrip
found 4 days ago
Select Air Europa flight, departing Thu, Apr 30 from Rome to Panama City, returning Wed, May 13, priced at $731 found 4 days ago
Air Europa
Fri, Sep 12 - Sun, Sep 28
FCO
Rome
PTY
Panama City
$732 Roundtrip, found 4 days ago
$732
Roundtrip
found 4 days ago
Select Air Europa flight, departing Fri, Sep 12 from Rome to Panama City, returning Sun, Sep 28, priced at $732 found 4 days ago
Air Europa
Sat, Nov 1 - Sat, Nov 8
FCO
Rome
PTY
Panama City
$740 Roundtrip, found 2 days ago
$740
Roundtrip
found 2 days ago
Select Air Europa flight, departing Sat, Nov 1 from Rome to Panama City, returning Sat, Nov 8, priced at $740 found 2 days ago
Air Europa
Wed, Sep 17 - Sun, Sep 28
FCO
Rome
PTY
Panama City
$743 Roundtrip, found 4 days ago
$743
Roundtrip
found 4 days ago
Select Air Europa flight, departing Wed, Sep 17 from Rome to Panama City, returning Sun, Sep 28, priced at $743 found 4 days ago
Iberia
Wed, Jan 21 - Sat, Jan 31
FCO
Rome
PTY
Panama City
$811 Roundtrip, found 1 day ago
$811
Roundtrip
found 1 day ago
Select Iberia flight, departing Wed, Jan 21 from Rome to Panama City, returning Sat, Jan 31, priced at $811 found 1 day ago
KLM
Fri, Aug 22 - Wed, Dec 24
FCO
Rome
PTY
Panama City
$833 Roundtrip, found 1 hour ago
$833
Roundtrip
found 1 hour ago
Select KLM flight, departing Fri, Aug 22 from Rome to Panama City, returning Wed, Dec 24, priced at $833 found 1 hour ago

Alternative airports near Panama City

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Tocumen Intl. PTY. Cheapest option available. Average driving time to city center is 16 minutes. Flights from $1,677
PTY
Tocumen Intl.
Cheapest
Average driving time to city center16 min
Flights from $1,677
Flights from Rome (FCO) to Panama City (PTY)
Origin airport
Fiumicino - Leonardo da Vinci Intl.
Destination airport
Tocumen Intl.
Airlines serving
Air Europa, Air France, American Airlines, Delta, Iberia, KLM, Turkish Airlines, United
Roundtrip price
$697
Distance
5885 mi

Rome to Panama City Flights

The cheapest times to fly from Rome to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Rome to Panama City are during the month of September. You can find some of the cheapest flights from Rome to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Rome to Panama City

Sunday is one of the best days to book for cheap flights from Rome to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Rome to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Rome to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $432 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Rome to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Rome to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Tocumen Intl. Airport (PTY) cost?
Discover the latest flight deals from FCO to PTY by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from FCO to PTY?
The cheapest flights from FCO to PTY are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from FCO to PTY?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from FCO to PTY. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Tocumen Intl. Airport (PTY)?
There aren't any daily direct flights departing from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Tocumen Intl. Airport (PTY). But you can choose flights with layovers. Filter your search on Expedia to include one or more stops, and you'll be soaring above the clouds in no time at all.
What day of the week has the most flights from FCO to PTY?
Friday is usually the busiest day for flights, while Tuesday is often the quietest.* Keep in mind that flight schedules can change based on a range of factors, including the airline and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Tocumen Intl. Airport (PTY)?
To reach Tocumen Intl. Airport (PTY) on time, select a flight that leaves from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Tocumen Intl. Airport (PTY) last-minute?
Waiting until just before your departure to book a ticket from FCO to PTY generally means paying more. While you might find some last-minute deals, they're not always guaranteed. Be flexible with your travel plans to maximize your chances of landing a bargain.
Is it cheaper to book a FCO to PTY flight and hotel package?
Compared with arranging hotels and flights separately, booking a FCO to PTY flight and hotel package with Expedia could result in significant savings. Better yet, having everything in one convenient place takes the hassle out of planning your trip. Simply secure your flights and choose from our wide range of stays, then tailor your trip with extras like car rentals and activities.
Can I cancel or change the date of my flight from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Tocumen Intl. Airport (PTY)?
If you booked your FCO to PTY flight in the last 24 hours, you may be able to cancel or modify it without fees. Depending on the airline and the type of ticket you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal if you'd like more information.

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*Available to One Key members.