$525 Cheap Flights from Islip (ISP) to São Paulo (GRU)

View $525 flight on Sat, Aug 23, 2025Opens in a new window

Popular airlines from MacArthur Airport (ISP) to São Paulo/Guarulhos Intl. Airport

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Cheap Flights from Islip to São Paulo (ISP-GRU)

Prices were available within the past 7 days and start at $525 for one-way flights and $797 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

JetBlue Airways
Wed, Sep 10 - Wed, Sep 17
ISP
Islip
GRU
Sao Paulo
$797 Roundtrip, found 6 days ago
$797
Roundtrip
found 6 days ago
Select JetBlue Airways flight, departing Wed, Sep 10 from Islip to Sao Paulo, returning Wed, Sep 17, priced at $797 found 6 days ago
JetBlue Airways
Wed, Sep 10 - Wed, Sep 17
ISP
Islip
GRU
Sao Paulo
$815 Roundtrip, found 6 days ago
$815
Roundtrip
found 6 days ago
Select JetBlue Airways flight, departing Wed, Sep 10 from Islip to Sao Paulo, returning Wed, Sep 17, priced at $815 found 6 days ago
JetBlue Airways
Wed, Sep 10 - Wed, Sep 17
ISP
Islip
GRU
Sao Paulo
$885 Roundtrip, found 6 days ago
$885
Roundtrip
found 6 days ago
Select JetBlue Airways flight, departing Wed, Sep 10 from Islip to Sao Paulo, returning Wed, Sep 17, priced at $885 found 6 days ago
JetBlue Airways
Wed, Sep 10 - Wed, Sep 17
ISP
Islip
GRU
Sao Paulo
$910 Roundtrip, found 6 days ago
$910
Roundtrip
found 6 days ago
Select JetBlue Airways flight, departing Wed, Sep 10 from Islip to Sao Paulo, returning Wed, Sep 17, priced at $910 found 6 days ago
JetBlue Airways
Wed, Sep 10 - Wed, Sep 17
ISP
Islip
GRU
Sao Paulo
$928 Roundtrip, found 6 days ago
$928
Roundtrip
found 6 days ago
Select JetBlue Airways flight, departing Wed, Sep 10 from Islip to Sao Paulo, returning Wed, Sep 17, priced at $928 found 6 days ago
JetBlue Airways
Wed, Sep 10 - Wed, Sep 17
ISP
Islip
GRU
Sao Paulo
$963 Roundtrip, found 6 days ago
$963
Roundtrip
found 6 days ago
Select JetBlue Airways flight, departing Wed, Sep 10 from Islip to Sao Paulo, returning Wed, Sep 17, priced at $963 found 6 days ago
JetBlue Airways
Wed, Sep 10 - Wed, Sep 17
ISP
Islip
GRU
Sao Paulo
$981 Roundtrip, found 6 days ago
$981
Roundtrip
found 6 days ago
Select JetBlue Airways flight, departing Wed, Sep 10 from Islip to Sao Paulo, returning Wed, Sep 17, priced at $981 found 6 days ago
JetBlue Airways
Wed, Sep 10 - Wed, Sep 17
ISP
Islip
GRU
Sao Paulo
$998 Roundtrip, found 6 days ago
$998
Roundtrip
found 6 days ago
Select JetBlue Airways flight, departing Wed, Sep 10 from Islip to Sao Paulo, returning Wed, Sep 17, priced at $998 found 6 days ago
JetBlue Airways
Wed, Sep 10 - Wed, Sep 17
ISP
Islip
GRU
Sao Paulo
$1,051 Roundtrip, found 6 days ago
$1,051
Roundtrip
found 6 days ago
Select JetBlue Airways flight, departing Wed, Sep 10 from Islip to Sao Paulo, returning Wed, Sep 17, priced at $1,051 found 6 days ago
JetBlue Airways
Wed, Sep 10 - Wed, Sep 17
ISP
Islip
GRU
Sao Paulo
$1,134 Roundtrip, found 6 days ago
$1,134
Roundtrip
found 6 days ago
Select JetBlue Airways flight, departing Wed, Sep 10 from Islip to Sao Paulo, returning Wed, Sep 17, priced at $1,134 found 6 days ago
JetBlue Airways
Sun, Feb 15 - Fri, Feb 20
ISP
Islip
GRU
Sao Paulo
$1,838 Roundtrip, found 2 days ago
$1,838
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Sun, Feb 15 from Islip to Sao Paulo, returning Fri, Feb 20, priced at $1,838 found 2 days ago
JetBlue Airways
Fri, Dec 26 - Sun, Jan 4
ISP
Islip
GRU
Sao Paulo
$1,974 Roundtrip, found 2 days ago
$1,974
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Fri, Dec 26 from Islip to Sao Paulo, returning Sun, Jan 4, priced at $1,974 found 2 days ago
JetBlue Airways
Sun, Feb 15 - Fri, Feb 20
ISP
Islip
GRU
Sao Paulo
$2,006 Roundtrip, found 2 days ago
$2,006
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Sun, Feb 15 from Islip to Sao Paulo, returning Fri, Feb 20, priced at $2,006 found 2 days ago
JetBlue Airways
Fri, Dec 26 - Sun, Jan 4
ISP
Islip
GRU
Sao Paulo
$2,094 Roundtrip, found 2 days ago
$2,094
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Fri, Dec 26 from Islip to Sao Paulo, returning Sun, Jan 4, priced at $2,094 found 2 days ago
JetBlue Airways
Fri, Dec 26 - Sun, Jan 4
ISP
Islip
GRU
Sao Paulo
$2,114 Roundtrip, found 2 days ago
$2,114
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Fri, Dec 26 from Islip to Sao Paulo, returning Sun, Jan 4, priced at $2,114 found 2 days ago
Flights from Islip (ISP) to São Paulo (GRU)
Origin airport
MacArthur
Destination airport
Guarulhos - Governor André Franco Montoro Intl.
Roundtrip price
$797
Distance
4754 mi

Islip to São Paulo Flights

The cheapest times to fly from Islip to São Paulo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Islip to São Paulo are during the month of September. You can find some of the cheapest flights from Islip to São Paulo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Islip to São Paulo

Sunday is one of the best days to book for cheap flights from Islip to São Paulo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Islip to São Paulo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Islip to São Paulo in 2025. You can also book with separate airlines for your outbound and return journeys, from $525 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Islip to São Paulo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Islip to São Paulo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from MacArthur Airport (ISP) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU) cost?
Discover the latest flight deals from ISP to GRU by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from ISP to GRU?
The cheapest flights from ISP to GRU are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from MacArthur Airport (ISP) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU)?
You can't fly directly from Islip, NY (ISP-MacArthur) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU). However, there are other airports with nonstop flights. Begin your journey at John F. Kennedy Intl. Airport (JFK) and fly straight to Sao Paulo without a layover.
What is the cheapest airline that flies from ISP to GRU?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from ISP to GRU. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from MacArthur Airport (ISP) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU)?
You'll need to take a flight with a layover if you're traveling from MacArthur Airport (ISP) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU). Direct flights don't operate daily on this route. However, just filter your search to include one or two stops to find an option that works for you.
What day of the week has the most flights from ISP to GRU?
Friday is usually the busiest day for flights, while Tuesday tends to be the quietest.* Just remember that flight schedules can vary based on a range of factors, including the season and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from MacArthur Airport (ISP) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU)?
To reach Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU) on schedule, pick a flight that leaves from MacArthur Airport (ISP) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from MacArthur Airport (ISP) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU) last-minute?
Holding off until just before your trip to book your flight from ISP to GRU often results in higher prices. While you may find some last-minute offers, they aren't always guaranteed. Be flexible with your itinerary for a better chance of snagging a bargain.
Is it cheaper to book an ISP to GRU flight and hotel package?
You'll typically save money by securing an ISP to GRU flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one convenient place. After selecting your preferred accommodations and flights, consider adding extras including tours, car rentals and activities.
Can I cancel or change the date of my flight from MacArthur Airport (ISP) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU)?
If you reserved your ISP to GRU flight in the last 24 hours, you may be able to cancel or modify it without fees. Depending on the airline and the type of ticket you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal for more details.

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*Available to One Key members.