$210 Cheap Flights from Mendoza (MDZ) to Cusco (CUZ)

View $210 flight on Wed, Mar 11, 2026Opens in a new window

Popular airlines from Mendoza (MDZ-Governor Francisco Gabrielli Intl.) to Alejandro Velasco Astete Intl. Airport (CUZ)

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Cheap Flights from Mendoza to Cusco (MDZ-CUZ)

Prices were available within the past 7 days and start at $210 for one-way flights and $369 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

LATAM Airlines Group
Fri, Apr 10 - Thu, Apr 23
MDZ
Mendoza
CUZ
Cusco
$369 Roundtrip, found 5 days ago
$369
Roundtrip
found 5 days ago
Select LATAM Airlines Group flight, departing Fri, Apr 10 from Mendoza to Cusco, returning Thu, Apr 23, priced at $369 found 5 days ago
LATAM Airlines Group
Fri, Apr 10 - Thu, Apr 23
MDZ
Mendoza
CUZ
Cusco
$381 Roundtrip, found 5 days ago
$381
Roundtrip
found 5 days ago
Select LATAM Airlines Group flight, departing Fri, Apr 10 from Mendoza to Cusco, returning Thu, Apr 23, priced at $381 found 5 days ago
LATAM Airlines Group
Fri, Jan 16 - Fri, Jan 23
MDZ
Mendoza
CUZ
Cusco
$438 Roundtrip, found 3 days ago
$438
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Fri, Jan 16 from Mendoza to Cusco, returning Fri, Jan 23, priced at $438 found 3 days ago
LATAM Airlines Group
Fri, Apr 10 - Thu, Apr 23
MDZ
Mendoza
CUZ
Cusco
$440 Roundtrip, found 5 days ago
$440
Roundtrip
found 5 days ago
Select LATAM Airlines Group flight, departing Fri, Apr 10 from Mendoza to Cusco, returning Thu, Apr 23, priced at $440 found 5 days ago
LATAM Airlines Group
Fri, Apr 10 - Thu, Apr 23
MDZ
Mendoza
CUZ
Cusco
$472 Roundtrip, found 5 days ago
$472
Roundtrip
found 5 days ago
Select LATAM Airlines Group flight, departing Fri, Apr 10 from Mendoza to Cusco, returning Thu, Apr 23, priced at $472 found 5 days ago
LATAM Airlines Group
Fri, Apr 10 - Thu, Apr 23
MDZ
Mendoza
CUZ
Cusco
$485 Roundtrip, found 5 days ago
$485
Roundtrip
found 5 days ago
Select LATAM Airlines Group flight, departing Fri, Apr 10 from Mendoza to Cusco, returning Thu, Apr 23, priced at $485 found 5 days ago
LATAM Airlines Group
Fri, Jan 16 - Fri, Jan 23
MDZ
Mendoza
CUZ
Cusco
$497 Roundtrip, found 3 days ago
$497
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Fri, Jan 16 from Mendoza to Cusco, returning Fri, Jan 23, priced at $497 found 3 days ago
LATAM Airlines Group
Fri, Apr 10 - Thu, Apr 23
MDZ
Mendoza
CUZ
Cusco
$508 Roundtrip, found 5 days ago
$508
Roundtrip
found 5 days ago
Select LATAM Airlines Group flight, departing Fri, Apr 10 from Mendoza to Cusco, returning Thu, Apr 23, priced at $508 found 5 days ago
LATAM Airlines Group
Fri, Apr 10 - Thu, Apr 23
MDZ
Mendoza
CUZ
Cusco
$520 Roundtrip, found 5 days ago
$520
Roundtrip
found 5 days ago
Select LATAM Airlines Group flight, departing Fri, Apr 10 from Mendoza to Cusco, returning Thu, Apr 23, priced at $520 found 5 days ago
Aerolineas Argentinas
Fri, Apr 10 - Thu, Apr 23
MDZ
Mendoza
CUZ
Cusco
$562 Roundtrip, found 5 days ago
$562
Roundtrip
found 5 days ago
Select Aerolineas Argentinas flight, departing Fri, Apr 10 from Mendoza to Cusco, returning Thu, Apr 23, priced at $562 found 5 days ago
Flights from Mendoza (MDZ) to Cusco (CUZ)
Origin airport
Governor Francisco Gabrielli Intl.
Destination airport
Alejandro Velasco Astete Intl.
Roundtrip price
$368
Distance
1347 mi

Mendoza to Cusco Flights

The cheapest times to fly from Mendoza to Cusco

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Mendoza to Cusco are during the month of April. You can find some of the cheapest flights from Mendoza to Cusco with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Mendoza to Cusco

Sunday is one of the best days to book for cheap flights from Mendoza to Cusco: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Mendoza to Cusco

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Mendoza to Cusco in 2026. You can also book with separate airlines for your outbound and return journeys, from $210 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Mendoza to Cusco flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Mendoza to Cusco airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Governor Francisco Gabrielli Intl. Airport (MDZ) to Alejandro Velasco Astete Intl. Airport (CUZ) cost?
Secure a cheap one-way flight from $210 or cheap return flight from $369 from Governor Francisco Gabrielli Intl. Airport (MDZ) to Alejandro Velasco Astete Intl. Airport (CUZ) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Governor Francisco Gabrielli Intl. Airport (MDZ) to Alejandro Velasco Astete Intl. Airport (CUZ)?
April is the most affordable month to fly from MDZ to CUZ. Planning your trip for the off-season is often the key to better flight prices.
What is the cheapest airline that flies from Governor Francisco Gabrielli Intl. Airport (MDZ) to Alejandro Velasco Astete Intl. Airport (CUZ)?
Expedia's filter tool lets you easily compare different airlines, travel time and fares all in one place. Select your preferences, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest MDZ to CUZ flight.
How many flights per day from Governor Francisco Gabrielli Intl. Airport (MDZ) to Alejandro Velasco Astete Intl. Airport (CUZ)?
Direct flights from Governor Francisco Gabrielli Intl. Airport (MDZ) to Alejandro Velasco Astete Intl. Airport (CUZ) aren't available daily, so you'll have to take a flight with a layover. Explore your options with our filter tool. Enter your travel dates and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from MDZ to CUZ?
Generally you'll find the largest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* However, this can change based on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Governor Francisco Gabrielli Intl. Airport (MDZ) to Alejandro Velasco Astete Intl. Airport (CUZ)?
To avoid potential delays on the Governor Francisco Gabrielli Intl. Airport (MDZ) to Alejandro Velasco Astete Intl. Airport (CUZ) route, travel before 3 PM. Later departures have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Governor Francisco Gabrielli Intl. Airport (MDZ) to Alejandro Velasco Astete Intl. Airport (CUZ) last-minute?
Booking your plane ticket from MDZ to CUZ just before your getaway is generally more expensive. But if there's some wiggle room with your travel times and dates, you could score a cheap last-minute fare.
Is it cheaper to book a MDZ to CUZ flight and hotel package?
Compared with arranging flights and hotels separately, booking a MDZ to CUZ flight and hotel package with Expedia could lead to significant savings. What's more, having it all in one place takes the hassle out of planning your trip. Just pick your flights and choose from our wide range of stays, then tailor your trip with extras like tours, car rentals and activities.
Can I cancel or change the date of my flight from Governor Francisco Gabrielli Intl. Airport (MDZ) to Alejandro Velasco Astete Intl. Airport (CUZ)?
You can usually reschedule or cancel your MDZ to CUZ flight. However, for bookings made more than 24 hours ago, additional fees may apply. Check your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find further details on our Customer Service portal.

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*Available to One Key members.