$269 Cheap Flights from San Luis Obispo (SBP) to Panama City (PTY)

View $269 flight on Wed, Mar 4, 2026Opens in a new window

Cheap Flights from San Luis Obispo to Panama City (SBP-PTY)

Prices were available within the past 7 days and start at $269 for one-way flights and $568 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Mar 4 - Wed, Mar 11
SBP
San Luis Obispo
PTY
Panama City
$568 Roundtrip, found 2 days ago
$568
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Mar 4 from San Luis Obispo to Panama City, returning Wed, Mar 11, priced at $568 found 2 days ago
American Airlines
Wed, Mar 4 - Wed, Mar 11
SBP
San Luis Obispo
PTY
Panama City
$588 Roundtrip, found 2 days ago
$588
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Mar 4 from San Luis Obispo to Panama City, returning Wed, Mar 11, priced at $588 found 2 days ago
United
Fri, Mar 6 - Fri, Mar 13
SBP
San Luis Obispo
PTY
Panama City
$608 Roundtrip, found 2 days ago
$608
Roundtrip
found 2 days ago
Select United flight, departing Fri, Mar 6 from San Luis Obispo to Panama City, returning Fri, Mar 13, priced at $608 found 2 days ago
United
Wed, Mar 4 - Wed, Mar 11
SBP
San Luis Obispo
PTY
Panama City
$619 Roundtrip, found 2 days ago
$619
Roundtrip
found 2 days ago
Select United flight, departing Wed, Mar 4 from San Luis Obispo to Panama City, returning Wed, Mar 11, priced at $619 found 2 days ago
United
Wed, Mar 4 - Wed, Mar 11
SBP
San Luis Obispo
PTY
Panama City
$620 Roundtrip, found 2 days ago
$620
Roundtrip
found 2 days ago
Select United flight, departing Wed, Mar 4 from San Luis Obispo to Panama City, returning Wed, Mar 11, priced at $620 found 2 days ago
American Airlines
Wed, Mar 4 - Wed, Mar 11
SBP
San Luis Obispo
PTY
Panama City
$629 Roundtrip, found 2 days ago
$629
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Mar 4 from San Luis Obispo to Panama City, returning Wed, Mar 11, priced at $629 found 2 days ago
American Airlines
Wed, Mar 4 - Wed, Mar 11
SBP
San Luis Obispo
PTY
Panama City
$633 Roundtrip, found 2 days ago
$633
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Mar 4 from San Luis Obispo to Panama City, returning Wed, Mar 11, priced at $633 found 2 days ago
United
Wed, Mar 4 - Wed, Mar 11
SBP
San Luis Obispo
PTY
Panama City
$635 Roundtrip, found 2 days ago
$635
Roundtrip
found 2 days ago
Select United flight, departing Wed, Mar 4 from San Luis Obispo to Panama City, returning Wed, Mar 11, priced at $635 found 2 days ago
United
Wed, Mar 4 - Wed, Mar 11
SBP
San Luis Obispo
PTY
Panama City
$638 Roundtrip, found 2 days ago
$638
Roundtrip
found 2 days ago
Select United flight, departing Wed, Mar 4 from San Luis Obispo to Panama City, returning Wed, Mar 11, priced at $638 found 2 days ago
Copa
Wed, Mar 4 - Wed, Mar 11
SBP
San Luis Obispo
PTY
Panama City
$1,281 Roundtrip, found 2 days ago
$1,281
Roundtrip
found 2 days ago
Select Copa flight, departing Wed, Mar 4 from San Luis Obispo to Panama City, returning Wed, Mar 11, priced at $1,281 found 2 days ago

Frequently asked questions

How much does a flight from San Luis Obispo County Regional Airport (SBP) to Tocumen Intl. Airport (PTY) cost?
Lock in a cheap one-way flight from $269 or cheap return flight from $568 from San Luis Obispo County Regional Airport (SBP) to Tocumen Intl. Airport (PTY) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from San Luis Obispo County Regional Airport (SBP) to Tocumen Intl. Airport (PTY)?
March is the most affordable month to fly from SBP to PTY. Avoiding peak travel times is often the key to landing a great deal.
What is the cheapest airline that flies from San Luis Obispo County Regional Airport (SBP) to Tocumen Intl. Airport (PTY)?
Use the filters on Expedia to compare airlines and find the most affordable carrier that'll take you from SBP to PTY. Then, sort your results by "Price (lowest to highest)" to score the best deal available.
How many flights per day from San Luis Obispo County Regional Airport (SBP) to Tocumen Intl. Airport (PTY)?
Direct flights from San Luis Obispo County Regional Airport (SBP) to Tocumen Intl. Airport (PTY) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your dates and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from SBP to PTY?
Usually you'll find the greatest selection of flight options on a Friday. Tuesdays are often the quietest.* However, this can change depending on the airline, season and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from San Luis Obispo County Regional Airport (SBP) to Tocumen Intl. Airport (PTY)?
To land at Tocumen Intl. Airport (PTY) on schedule, book a flight that leaves San Luis Obispo County Regional Airport (SBP) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from San Luis Obispo County Regional Airport (SBP) to Tocumen Intl. Airport (PTY) last-minute?
Waiting until right before your break to book a ticket from SBP to PTY generally means paying more. While it's possible to find some last-minute deals, there's no guarantee. Keep your travel plans flexible for the best chance of scoring a bargain.
Is it cheaper to book a SBP to PTY flight and hotel package?
You'll typically save money by booking a SBP to PTY flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one place. After selecting your preferred accommodations and flights, consider adding extras such as tours, car rentals and activities.
Can I cancel or change the date of my flight from San Luis Obispo County Regional Airport (SBP) to Tocumen Intl. Airport (PTY)?
Generally, it's possible to reschedule or cancel your SBP to PTY flight. However, for bookings made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find further details on our Customer Service portal.

Travel information

Origin airport
San Luis Obispo County Regional
Destination airport
Tocumen Intl.
Roundtrip price
$568
Distance
3163 mi

Book with confidence

San Luis Obispo to Panama City Flights

The cheapest times to fly from San Luis Obispo to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from San Luis Obispo to Panama City are during the month of March. You can find some of the cheapest flights from San Luis Obispo to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from San Luis Obispo to Panama City

Sunday is one of the best days to book for cheap flights from San Luis Obispo to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from San Luis Obispo to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from San Luis Obispo to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $269 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap San Luis Obispo to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your San Luis Obispo to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

San Luis Obispo to Panama City Flights

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*Available to One Key members.