Eastern Tennessee Luxury Vacations

Book a Luxury Hotel + Flight or Car together to unlock savings

Top Luxury vacation packages in Eastern Tennessee

Price found within the past 48 hours. Click for updated prices.
Black Fox Lodge Pigeon Forge, Tapestry Collection by Hilton
THE TENNESSEAN Hotel
The Read House Hotel
Dollywood's DreamMore Resort
Carnegie Hotel & Spa
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3 Night Luxury vacations in Eastern Tennessee

Price found within the past 48 hours. Click for updated prices.
THE TENNESSEAN Hotel
Black Fox Lodge Pigeon Forge, Tapestry Collection by Hilton
The Read House Hotel
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See all available trips from Columbus to Eastern Tennessee
View all trips

4 Night Luxury vacations in Eastern Tennessee

Price found within the past 48 hours. Click for updated prices.
Hilton Knoxville
THE TENNESSEAN Hotel
Creekstone Inn
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See all available trips from Columbus to Eastern Tennessee
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All you need to know about luxury vacations in Eastern Tennessee

What can I expect from a luxury Eastern Tennessee vacation?

Luxury means the very finest of the things you enjoy most. Indulge your every waking moment—and restful night—with a luxury Eastern Tennessee vacation. Sip handcrafted cocktails by an infinity pool, sink into bliss at a full-service spa with a massage cabana on the beach, and chat, cheers, and laugh through exquisite breakfasts, lunches, and dinners with spectacular views. 

How can I find all-inclusive luxury vacation packages in Eastern Tennessee?

By refining your filters, the most opulent all-inclusive vacation packages will appear before your eyes. Check the 5* filter to find truly sensational stays. You barely need to lift a finger. 

Can I book a cheap Eastern Tennessee luxury vacation?

Affordable luxury is only ever a few clicks away. Enter your travel dates and sort the grandiose getaways on offer by price to see the most fiscally friendly retreats first. Filter by budget, too, to find your perfect balance of luxury. Right now, luxury vacations start at $552. Prices and availability are subject to change. Additional terms may apply.

How can I book a luxury family vacation in Eastern Tennessee?

Tailor your luxury family escape by checking the filters that set the whole family’s hearts a-flutter. Whether that’s wet and wild water parks, heavenly hot tubs, or the kid-quieting magic of free Wi-Fi. 

Can I book a package in Eastern Tennessee with a luxury vacation home?

A private paradise is true luxury! Filter by property type for houses, villas, and apartments. For an amazingly affordable all-in-one luxury experience, book your accommodation, airfare, and car rental as a package.   

How can I find the best luxury vacation deals in Eastern Tennessee?

Find absolute delight in the dropdown! Simply sort your tempting search results by deals to find that lean-budget luxury. For a budget conscious stay, consider booking a stay away from big cities or outside the peak months.

Can I book a luxury holiday in Eastern Tennessee with free cancellation and/or flexible dates?

Freedom and flexibility are the greatest luxuries of all. Get both when you filter by payment option and book a trip with free cancellation or on a buy now, pay later plan. 

Why should I book my luxury trip to Eastern Tennessee with Expedia?

A luxurious trip follows a stress-free booking experience. Find, build, and book the most glorious of getaways in seconds—with ATOL protection for added peace of mind.

Top Luxury Eastern Tennessee Hotels

Carnegie Hotel & Spa

Carnegie Hotel & Spa

4 out of 5
1216 W State Of Franklin Rd, Johnson City, TN
  • 1 hour drive from Dollywood
Treat yourself to upscale accommodations at Carnegie Hotel & Spa, where you'll enjoy amenities like premium channels and more. Notable amenities include a spa, ...
9.6/10 Exceptional! (1,270 reviews)
The fastest check in ever. Great staff, efficient and welcoming.

Reviewed on Oct 19, 2025

Carnegie Hotel & Spa
THE TENNESSEAN Hotel

THE TENNESSEAN Hotel

4 out of 5
531 Henley Street, Knoxville, TN
  • 32 min drive from Dollywood
Treat yourself to a luxury stay at THE TENNESSEAN Hotel, where you can enjoy amenities like pillowtop beds, designer toiletries, and more. The restaurant, fitness ...
9.4/10 Exceptional! (1,019 reviews)
Good location and pleasant staff

Reviewed on Oct 18, 2025

THE TENNESSEAN Hotel
The Read House Hotel

The Read House Hotel

4 out of 5
107 West Martin Luther King Blvd, Chattanooga, TN
  • 3 hours drive from Dollywood
Go for a luxurious stay at The Read House Hotel, where you can enjoy amenities like Champagne service, plush bedding, and more. The indoor pool, restaurant, ...
9.4/10 Exceptional! (2,210 reviews)
Love the location and the hotel decor/feel. I would stay here again for sure. Very convenient to all the shops and restaurants. We didn't need a car all weekend.

Reviewed on Oct 21, 2025

The Read House Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.