Midtown, MO

St. Louis

A historic building with a large lawn, a flagpole with flags, and a clear blue sky.
A sundae with chocolate ice cream and whipped cream.
A cathedral interior with Gothic architecture, including pointed arches and ribbed vaults.
A Gothic-style cathedral with intricate stonework, pointed arches, and statues.
A highway with multiple lanes, vehicles, and a bridge overhead.

Stay near popular Midtown attractions

Things to do


Midtown Hotel Deals

Element by Marriott St. Louis Midtown

Element by Marriott St. Louis Midtown

3 out of 5
3763 Forest Park Avenue St. Louis MO
$132 nightly
The price is $154 total per night from Sep 27 to Sep 28
$154 total
Sep 27 - Sep 28
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (821 reviews)
"Do not stay here, they eliminated the security team, increased the parking per day to forty-five dollars, valet drivers are high on marijuana, Customers being towed right and left."

Reviewed on Sep 9, 2026

Element by Marriott St. Louis Midtown
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
$152 nightly
The price is $179 total per night from Oct 4 to Oct 5
$179 total
Oct 4 - Oct 5
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (4,244 reviews)
"We loved the clean, comfortable room and friendly staff. At check in, the front desk provides an area map to the guests, which is very helpful. The location is great...walking distance to several sites, including Busch Stadium. Our only complaint was the poor water pressure in the shower, which really ..."

Reviewed on Sep 11, 2026

Hyatt Regency St. Louis at The Arch
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
$92 nightly
The price is $107 total per night from Oct 4 to Oct 5
$107 total
Oct 4 - Oct 5
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (3,380 reviews)
"Free breakfast Free parking Pool Fridge Microwave"

Reviewed on Sep 10, 2026

Clayton Plaza Hotel & Extended Stay
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road St. Louis MO
$123 nightly
The price is $144 total per night from Oct 2 to Oct 3
$144 total
Oct 2 - Oct 3
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
Renaissance St. Louis Airport Hotel
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
$89 nightly
The price is $105 total per night from Sep 22 to Sep 23
$105 total
Sep 22 - Sep 23
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (3,229 reviews)
"Great experience. I flew in for a show; staff were very friendly and helpful, and the location was great for what I needed, as I was able to use the airport shuttle to get Metro Link access which made getting downtown and back for the show a snap. Room was well maintained; great water pressure and ..."

Reviewed on Sep 11, 2026

Pear Tree Inn St. Louis Airport
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
$135 nightly
The price is $158 total per night from Oct 4 to Oct 5
$158 total
Oct 4 - Oct 5
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in our ...
9.6/10 Exceptional! (3,731 reviews)
"Location fit my needs perfectly. The entire staff was excellent. Will definitely stay here when in St. Louis"

Reviewed on Sep 10, 2026

Drury Plaza Hotel St. Louis at the Arch
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Midtown

Find the best Midtown areas and neighborhoods for the activities you enjoy most.

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Gateway Arch National Park might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Central West End

The ample dining options and lush forests are just a few popular features of the neighborhood. Make a stop by World Chess Hall of Fame or Blue Strawberry while you're visiting, and jump aboard the metro at Central West End Station to get around town.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

St. Charles Historic District

St. Charles Historic District is known for its abundant dining options, and you can plan a trip to Historic Main Street and Missouri River while you're in town.



Midtown, MO

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