Midtown, MO

St. Louis

A historic building with a large lawn, a flagpole with flags, and a clear blue sky.
A sundae with chocolate ice cream and whipped cream.
A cathedral interior with Gothic architecture, including pointed arches and ribbed vaults.
A Gothic-style cathedral with intricate stonework, pointed arches, and statues.
A highway with multiple lanes, vehicles, and a bridge overhead.

Stay near popular Midtown attractions

Things to do


Midtown Hotel Deals

Element by Marriott St. Louis Midtown

Element by Marriott St. Louis Midtown

3 out of 5
3763 Forest Park Avenue St. Louis MO
$135 nightly
The price is $158 total per night from Aug 16 to Aug 17
$158 total
Aug 16 - Aug 17
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
9/10 Wonderful! (788 reviews)
"Clean, with very comfortable beds, a great kitchenette (in my room, at least), & a better than average breakfast. Be aware that the “cooked-to-order” breakfast sounds more expansive than it really is; but it’s still better than average."

Reviewed on Jul 24, 2026

Element by Marriott St. Louis Midtown
Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown

3 out of 5
525 S Jefferson Ave St. Louis MO
$118 nightly
The price is $140 total per night from Aug 10 to Aug 11
$140 total
Aug 10 - Aug 11
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Our guests praise the breakfast ...
7.8/10 Good! (1,003 reviews)
"Has to wait and request the room I booked. The hotel smelled like weed."

Reviewed on Jul 24, 2026

Residence Inn by Marriott St Louis Downtown
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
$152 nightly
The price is $179 total per night from Jul 31 to Aug 1
$179 total
Jul 31 - Aug 1
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
Hyatt Regency St. Louis at The Arch
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $110 total per night from Aug 9 to Aug 10
$110 total
Aug 9 - Aug 10
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
9/10 Wonderful! (3,274 reviews)
"Stayed 4. days room were not made. Requested towels only received clean towels 2 days. A lot of walking from only area to another. Request handicapped room but room wasn’t handicapped equip. Parking area was dirty and very tight for large cars. Damage car trying to maneuver around in the garage."

Reviewed on Jul 25, 2026

Clayton Plaza Hotel & Extended Stay
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
$139 nightly
The price is $162 total per night from Aug 3 to Aug 4
$162 total
Aug 3 - Aug 4
Total with taxes and fees
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
8.6/10 Excellent! (2,208 reviews)
"Checking in is easy & rooms are pretty decent, paying for wifi and parking with no breakfast included is a negative but proximity to the concerts is a plus."

Reviewed on Jul 25, 2026

Hollywood Casino & Hotel St. Louis
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
$90 nightly
The price is $106 total per night from Aug 2 to Aug 3
$106 total
Aug 2 - Aug 3
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Pear Tree Inn St. Louis Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Midtown

Find the best Midtown areas and neighborhoods for the activities you enjoy most.

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Busch Stadium might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Downtown West

If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.

Central West End

The ample dining options and lush forests are just a few popular features of the neighborhood. Make a stop by World Chess Hall of Fame or Blue Strawberry while you're visiting, and jump aboard the metro at Central West End Station to get around town.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.



Midtown, MO

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