Midtown Vacations from $240
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Your Midtown Vacation
Organizing your next getaway just got easier with a vacation package to Midtown. Take in the very best this neighborhood has to offer while making incredible memories you'll treasure. Your trip to Midtown wouldn't be complete without exploring leading attractions nearby such as Busch Stadium, Gateway Arch and Dome at America’s Center. No matter what your dream Midtown vacation looks like, you can make it a reality with Expedia.
The Latest Midtown Vacation Packages
Hilton Garden Inn Chesterfield
Reviewed on Oct 26, 2025
The Wildwood Hotel
Reviewed on Nov 3, 2025
White House at Grand Central
Reviewed on Oct 23, 2025
Where to stay in Midtown
Downtown St. Louis
Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.
Midtown Hotel Deals
Residence Inn by Marriott St Louis Downtown
Love the 2 bedroom reservation: one bedroom with a king bed as well as a bathroom with the 2nd bedroom with 2 double beds as well with a bathroom. Love the couch, TV area as well as a kitchen. With my daughter having celiac, we must carry food safe for her to eat. The full sized fridge was great ...
Reviewed on Oct 14, 2025
Element St. Louis Midtown
The breakfast was good, timely and organized well. The room was clean and noise levels across rooms were not high. The location was ideal for my business trip. I also used the Gym and felt it was sufficient for my daily needs. The staff at the desk day/night were awake alert and well mannered. Would ...
Reviewed on Nov 1, 2025
Clayton Plaza Hotel & Extended Stay
Clean room. Quiet & restful. The bed is very firm. I appreciate the accessible outlets everywhere and the furniture in the room is actually useful. The free breakfast is more than most hotels and the staff is gracious. They really can't help the bizarre layout of the building & maze of hallways , ...
Reviewed on Nov 1, 2025
Discover the most popular places to visit in Midtown
St. Louis University
Explore the campus of St. Louis University as part of your travels around St. Louis. Wander around the area's picturesque gardens or experience its acclaimed theater scene.
Scott Joplin House State Historic Site
Learn about the local history of St. Louis when you spend time at Scott Joplin House State Historic Site. Experience the area's fascinating museums or attend a baseball game.
Chaifetz Arena
Catch an event at Chaifetz Arena during your trip to St. Louis. Amble around the area's picturesque gardens or attend a baseball game.
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
St Louis Arch Small Group Walking Tour and Arch Entrance Ticket
