Clayton, MO

St. Louis

Clayton
Photo by Najib Tecle
Photo by kirk allen
Photo by Sarah Mather

Popular places to visit

Things to do


Clayton Hotel Deals

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
$98 nightly
The price is $115 total per night from Oct 5 to Oct 6
$115 total
Oct 5 - Oct 6
Total with taxes and fees
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (2,911 reviews)
"Definitely recommend"

Reviewed on Sep 10, 2025

Clayton Plaza Hotel & Extended Stay
AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton

3 out of 5
227 South Central Ave, St. Louis, MO
$122 nightly
The price is $142 total per night from Oct 5 to Oct 6
$142 total
Oct 5 - Oct 6
Total with taxes and fees
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Popular attractions St. Louis Zoo and Forest Park ...
9/10 Wonderful! (173 reviews)
Amazing
"Excellent customer service can’t wait to come back."

Reviewed on Sep 7, 2025

AC Hotel St. Louis Clayton
Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton

4 out of 5
7730 Bonhomme Ave, St. Louis, MO
$165 nightly
The price is $193 total per night from Sep 28 to Sep 29
$193 total
Sep 28 - Sep 29
Total with taxes and fees
Book a stay at this eco-certified hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
8.8/10 Excellent! (654 reviews)
"The room was clean and service was excellent."

Reviewed on Sep 7, 2025

Le Méridien St. Louis Clayton
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

5 out of 5
100 Carondelet Plaza, St. Louis, MO
$489 nightly
The price is $570 total per night from Oct 5 to Oct 6
$570 total
Oct 5 - Oct 6
Total with taxes and fees
Stay at this 5-star luxury hotel in St. Louis. Enjoy breakfast (surcharge), room service, and a fitness center. Our guests praise the helpful staff and the room ...
9.2/10 Wonderful! (548 reviews)
"Service is exceptional!!!"

Reviewed on Sep 2, 2025

The Ritz-Carlton, St. Louis
Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Hampton Inn & Suites Clayton/St. Louis-Galleria Area

3 out of 5
216 N Meramec Ave, St. Louis, MO
$138 nightly
The price is $162 total per night from Oct 12 to Oct 13
$162 total
Oct 12 - Oct 13
Total with taxes and fees
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (877 reviews)
"Very convenient"

Reviewed on Aug 17, 2025

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive, Maryland Heights, MO
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $143 total per night from Sep 15 to Sep 16
$143 total
Sep 15 - Sep 16
Total with taxes and fees
Stay at this 3.5-star business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
8.4/10 Very Good! (2,124 reviews)
"walking distance to the stl music park."

Reviewed on Sep 10, 2025

Hollywood Casino & Hotel St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Clayton

#lifeatexpedia

Dogtown

If you're looking for some top things to see and do in Dogtown and surrounding area, you can visit St. Louis Zoo and St. Louis Art Museum.

Dogtown
New Loop Trolley at Delmar St Louis

University City

Noted for its shopping and restaurants, there's plenty to explore in University City. Top attractions like Museum of Transportation and Center of Creative Arts are major draws, and you can hop on the metro at Forsyth Station or U City Big Bend Station to see more of the city.

University City
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Ladue

The restaurants and churches are a few reasons travelers visit Ladue. Though there aren't many top sights in the neighborhood, you can visit Saint Louis Galleria Mall and St. Louis Art Museum, a few notable attractions nearby.

Ladue
Fantastic toasted ravioli, a quintessential St. Louis dish. Excellent restaurant located on the Hill, a large Italian neighborhood.
#localgem #Delicious

The Hill

If you're looking for some top things to see and do in The Hill and surrounding area, you can visit St. Louis Science Center and Missouri Botanical Gardens and Arboretum.

The Hill
Central West End

Central West End

4.5/5(450 area reviews)

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Central West End
Not just bars but also loft apartments are lit in rainbow lights for Pride weekend in the Grove neighborhood in St. Louis! #LifeAtExpedia

The Grove

The Grove might not have many top sights, but St. Louis Science Center and Missouri Botanical Gardens and Arboretum are two attractions nearby that you can check out.

The Grove

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Clayton, MO

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