Santa Cruz

Seville

A narrow cobblestone street lined with colorful buildings, shops, and a prominent white archway in the distance.
A historic plaza with ornate Gothic architecture, palm trees, and people walking.
A narrow street lined with trees and buildings, with people sitting at outdoor cafes.
A sunny urban square with tram tracks, historic buildings, and pedestrians.
A historic building with ornate columns, a large archway, and a statue.
Wander through a maze of cobbled streets in one of Seville's most picturesque areas, an ancient neighborhood that's home to major landmarks and medieval buildings.

Santa Cruz is one of the oldest neighborhoods in the city. The former medieval Jewish quarter is known for its squares framed by orange trees, narrow streets that keep out the sun, whitewashed homes adorned by flower-filled balconies and Seville's main monuments, the cathedral and the Giralda. Visit Santa Cruz on foot and discover insights into its long and fascinating past.

Nestled in the heart of the neighborhood or barrio is the 15th-century Seville Cathedral, a massive gothic structure that is one of the largest churches in the world. Marvel at centuries-old frescoes that adorn chapels, visit the tomb of explorer Christopher Columbus and climb up the bell tower, the Giralda. This was the tallest building in the city for hundreds of years, and its oldest part is a minaret from the 12th century.

Then walk over to the 14th-century mudejar-style Royal Alcazar of Seville, which is still used by the Spanish royal family when they're in the city.

Meander down extremely narrow pedestrianized streets called kissing lanes because the houses on opposite sides are so close. The streets were designed like this to maximize shade. Pause to admire tiled patios of mansions and townhouses through their wrought-iron gates.

Visit the Casa Fabiola for its collection of paintings, sculptures and religious pieces. Adjoining this renaissance Sevillian palace is a section of the wall that encircled the old Jewish quarter.

Trace the history of Seville's Jewish community by studying the artifacts and information panels at the Centro de Interpretación Judería de Sevilla.

Unwind in one of the beautiful squares that dot the neighborhood, such as Plaza Doña Elvira with its fountain, tiled benches and orange trees. Enjoy more tranquil moments in the Jardines de Murillo, a peaceful oasis of flowerbeds, fountains, arbors and magnolia trees, among other species.

Find the Santa Cruz neighborhood in the historic center of the city and enjoy its charm, beauty and atmosphere as you stroll through the cobblestone streets.


Stay near popular Santa Cruz attractions

Things to do


Santa Cruz Hotel Deals

Las Casas de la Judería, Sevilla Historic City Center

Las Casas de la Judería, Sevilla Historic City Center

4 out of 5
Calle Santa Maria La Blanca 5 Seville Seville
$105 nightly
The price is $115 total per night from Dec 1 to Dec 2
$115 total
Dec 1 - Dec 2
Total with taxes and fees
Book a stay at this spa hotel in Seville. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the pool and the helpful staff in our reviews. ...
Las Casas de la Judería, Sevilla Historic City Center
Hotel Amadeus Sevilla

Hotel Amadeus Sevilla

4 out of 5
Calle Farnesio 6 Seville Seville
$118 nightly
The price is $130 total per night from Dec 10 to Dec 11
$130 total
Dec 10 - Dec 11
Total with taxes and fees
Book a stay at this boutique hotel in Seville. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the breakfast and the bar in ...
9.6/10 Exceptional! (1,307 reviews)
"Such a special hotel. CLOSE to everything, but tucked away on a quintessential alley that is so perfect and special. Make sure you ask about the breakfast protocol, it is slightly different than what you would expect. It was good if you’re in a pinch and need something convenient and easy, but don’t ..."

Reviewed on Nov 9, 2026

Hotel Amadeus Sevilla
Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

5 out of 5
San Fernando 2 Seville Seville
$411 nightly
The price is $452 total per night from Dec 10 to Dec 11
$452 total
Dec 10 - Dec 11
Total with taxes and fees
Book a stay at this luxury hotel in Seville. Enjoy 2 restaurants, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff in our ...
9.4/10 Exceptional! (1,001 reviews)
"Na"

Reviewed on Nov 8, 2026

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
Hotel Fernando III

Hotel Fernando III

4 out of 5
San Jose 21 Seville Seville
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $122 total per night from Dec 8 to Dec 9
$122 total
Dec 8 - Dec 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Seville. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the breakfast and the pool ...
9.6/10 Exceptional! (1,388 reviews)
"We stayed for 3 nights and could not have been more satisfied. The staff was exceptionally friendly and accommodating. The room was large (especially for Europe) and very comfortable. The breakfast was excellent. The rooftop offered lots of space and seating, a nice pool, and an excellent view. Perhaps ..."

Reviewed on Nov 5, 2026

Hotel Fernando III
Hotel Rey Alfonso X

Hotel Rey Alfonso X

4 out of 5
Calle Ximenez De Enciso, 35 Seville Seville
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $122 total per night from Dec 8 to Dec 9
$122 total
Dec 8 - Dec 9
Total with taxes and fees
Stay at this hotel in Seville. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the breakfast and the pool in our reviews. Popular ...
9.4/10 Exceptional! (1,220 reviews)
"We had a wonderful stay at this hotel. The rooms were of a good size with personal touches of embossed pillows and towels. The rooftop bar was a great bonus and we enjoyed drinks looking at the beautiful view. Staff were helpful and kind and the location of the hotel is perfect for exploring Seville ..."

Reviewed on Nov 8, 2026

Hotel Rey Alfonso X
Hotel Doña Maria

Hotel Doña Maria

4 out of 5
Don Remondo 19 Seville Seville
$102 nightly
The price is $112 total per night from Dec 9 to Dec 10
$112 total
Dec 9 - Dec 10
Total with taxes and fees
Book a stay at this historic hotel in Seville. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular ...
9.2/10 Wonderful! (1,005 reviews)
"Beautiful old world architecture and decorations. Nice roof top area."

Reviewed on Nov 8, 2026

Hotel Doña Maria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
Learn more about Santa Cruz

Historical Center

Casa de la Memoria Cultural Center and Calle Sierpes are a few top attractions in Historical Center. Hop around the city on the metro at Plaza Nueva Tram Stop or Archivo de Indias Tram Stop and check out the area's fantastic nightlife, stunning cathedral, and popular shops.

El Arenal

Travelers choose El Arenal for its ample dining options. Hop aboard the metro at Plaza Nueva Tram Stop or Archivo de Indias Tram Stop and check out top sights like Teatro Maestranza.

Alfalfa

Unique features of Alfalfa include the bars and historic sites. Make a stop by Calle Sierpes or Casa de la Memoria Cultural Center while you're exploring the area.

Triana

Known for its abundant dining options and stunning river views, there's plenty to explore in Triana. Top attractions like Triana Market and Triana Bridge are major draws, and you can catch the metro at Plaza de Cuba Station or Cartuja Station to see more of the city.

San Bartolomé

Travelers come to San Bartolomé for its lively bars, and you can see top attractions like Pilate's House and Zurbarán Statue while you're in town.



Santa Cruz

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