Santa Cruz Vacations from $883
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Your Santa Cruz Vacation
Booking a Santa Cruz vacation package is a good way to become acquainted with this unique neighborhood. From its must-visit places to its lesser-known treasures, there's a lot to delve into. Some leading nearby attractions to check out during your trip to Santa Cruz include Seville Cathedral, Alcázar and Plaza de España. Whatever your dream Santa Cruz vacation looks like, you can turn it into reality with Expedia.
The Latest Santa Cruz Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Eurostars Guadalquivir
Los Remedios
Price was $1,202, price is now $883 per person
$883
per person
Apr 10 - Apr 14
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Seville (SVQ)
9.4/10 Exceptional! (507 reviews)
Nos encanto! Todo perfecto!! La ubicacion, el servicio, la gente, la lompieza. Todo super
Reviewed on Jan 25, 2026
Triana House
Triana
Price was $1,448, price is now $979 per person
$979
per person
Apr 10 - Apr 14
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Seville (SVQ)
9.6/10 Exceptional! (73 reviews)
We could not have chosen a better place for our Seville vacation. The location was perfect, staff awesome( fantastic restaurant recommendations), rooms super clean with just the most comfortable bed possible. They even arranged for our airport transfer and tickets to a flamenco show. You’ll love it here.
Reviewed on Dec 30, 2025
Eurostars Sevilla Boutique
Historical Center
Save 100% on your flight
Price was $1,671, price is now $1,139 per person
$1,139
per person
Apr 10 - Apr 14
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Seville (SVQ)
9/10 Wonderful! (481 reviews)
We very much enjoyed our stay here. Excellent location. I would recommend.
Reviewed on Jan 17, 2026
Hotel Boutique Corral del Rey by ALUZ Collection
Historical Center
Save 100% on your flight
Price was $2,257, price is now $1,626 per person
$1,626
per person
Apr 17 - Apr 20
found 15 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Seville (SVQ)
9.6/10 Exceptional! (89 reviews)
Property is very quaint and walking distance to most of the sites and many restaurants. Room was very authentic. Staff was great. Breakfast is continental with yogurt, fruit, granola, coffee but you can pay for eggs and bacon. Lovely stay!
Reviewed on Jan 22, 2026
Apartamentos Metrópolis Sevilla
Historical Center
Price was $3,272, price is now $2,438 per person
$2,438
per person
Apr 18 - Apr 24
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Seville (SVQ)
8.8/10 Excellent! (176 reviews)
The location of this apartment is perfect - close to all touristic locations and pretty decent dining options etc.
Reviewed on Dec 23, 2025
Where to stay in Santa Cruz
Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
Historical Center
8 out of top 10 points of interest in this area
4.5/5(600 area reviews)
Go on an adventure through the ages when you visit the historical churches, palaces, plazas and mansions of Seville’s ancient heart.
Santa Cruz Hotel Deals
Las Casas de la Judería, Sevilla Historic City Center
Calle Santa Maria La Blanca 5 Seville Seville
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $135 total per night from Feb 2 to Feb 3
$135 total
Feb 2 - Feb 3
Total with taxes and fees
9.2/10 Wonderful! (1,004 reviews)
Really unique hotel with many courtyards. Nice spacious room with moderate size bathroom . Nice breakfast area and piano bar. Fantastic location . David from the Rock.🇨🇦🇨🇦🇨🇦 (Platinum Expedia )
Reviewed on Jan 18, 2026
Hotel Fernando III
San Jose 21 Seville Seville
Fully refundableReserve now, pay when you stay
$128 nightly
The price is $141 total per night from Feb 8 to Feb 9
$141 total
Feb 8 - Feb 9
Total with taxes and fees
9.6/10 Exceptional! (1,521 reviews)
The room was clean , spacious and beautiful! The staff was generous with their time and very helpful. Great location.
Reviewed on Jan 26, 2026
Hotel Amadeus Sevilla
Calle Farnesio 6 Seville Seville
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $145 total per night from Feb 2 to Feb 3
$145 total
Feb 2 - Feb 3
Total with taxes and fees
9.6/10 Exceptional! (1,120 reviews)
A really nice, smaller hotel on the edge of the old part of the city, a short walking distance to the Alcazar. It is located on a narrow street, not accessible to cars. However, it is only a short distance to a wider street where you can be picked up, dropped off, etc. The hotel is quiet, well-appointed, ...
Reviewed on Jan 28, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Santa Cruz
Royal Alcázar of Seville
5/5(735 reviews)
Discover a millennium’s worth of royal treasures in this architectural masterpiece in the heart of Seville.
Giralda Tower
4.5/5(496 reviews)
Once among the tallest religious monuments in the world, this former minaret is now the eye-catching bell tower to Seville Cathedral.
San Telmo Palace
Tour the striking interior and exterior of a palatial building that serves as the headquarters of the president of the autonomous region of Andalusia.
Things to do
Cathedral & Alcázar of Seville Guided Tour Combo
$38
per adult
92% of travellers recommend
Sevilla Food Tour: Tapas, Wine, History & Traditions
$80
per adult
100% of travellers recommend
Ticket for Casa de la Guitarra Flamenco Show
$23
per adult
88% of travellers recommend
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.