Santa Cruz Vacations from $1,433
Book a Hotel + Flight or Car together to unlock savings
Your Santa Cruz Vacation
Booking a Santa Cruz vacation package is a good way to become acquainted with this unique neighborhood. From its must-visit places to its lesser-known treasures, there's a lot to delve into. Some leading nearby attractions to check out during your trip to Santa Cruz include Seville Cathedral, Alcázar and Plaza de España. Whatever your dream Santa Cruz vacation looks like, you can turn it into reality with Expedia.
The Latest Santa Cruz Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Hotel Eurostars Regina
Historical Center
Price was $1,878, price is now $1,433 per person
$1,433
per person
May 24 - May 30
just found
Roundtrip non-stop flight included
Los Angeles (LAX) to Seville (SVQ)
8/10 Very Good! (810 reviews)
Room and property were very clean.
Bed was very comfortable.
Would definitely stay again.
Reviewed on Jan 19, 2026
Hotel Vincci Molviedro Suites Apartments
Historical Center
Price was $2,627, price is now $1,867 per person
$1,867
per person
May 24 - May 30
just found
Roundtrip non-stop flight included
Los Angeles (LAX) to Seville (SVQ)
9.8/10 Exceptional! (111 reviews)
Best location clean spacious comfortable rooms suites staff behaviours was friendly and supportive
Near transport and shop’s
Nice stay
Reviewed on Jan 19, 2026
Eurostars Sevilla Boutique
Historical Center
Price was $2,647, price is now $1,894 per person
$1,894
per person
May 25 - May 31
found 3 hours ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Seville (SVQ)
9/10 Wonderful! (506 reviews)
We very much enjoyed our stay here. Excellent location. I would recommend.
Reviewed on Jan 17, 2026
Exe Sevilla Macarena
Macarena
Price was $2,295, price is now $1,712 per person
$1,712
per person
May 25 - May 31
found 3 hours ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Seville (SVQ)
8/10 Very Good! (1,006 reviews)
Room didnt smell good, would be nice if they have coffee in the room or vendo machine for hot bevereges in the lobby. Happy that they have vendo machine for cold drinks. Asked for a wakeup call but never got it. You can hear the voices and snoring of the people next door.
Reviewed on Feb 13, 2026
Eurostars Guadalquivir
Los Remedios
Price was $2,133, price is now $1,626 per person
$1,626
per person
May 25 - May 31
found 3 hours ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Seville (SVQ)
9.4/10 Exceptional! (562 reviews)
Desayuno variado. Me quedan a deber en la calidad del café
Reviewed on Mar 19, 2026
Where to stay in Santa Cruz
Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
Historical Center
8 out of top 10 points of interest in this area
4.5/5(604 area reviews)
Go on an adventure through the ages when you visit the historical churches, palaces, plazas and mansions of Seville’s ancient heart.
Santa Cruz Hotel Deals
Las Casas de la Judería, Sevilla Historic City Center
Calle Santa Maria La Blanca 5 Seville Seville
$193 nightly
The price is $212 total per night from Mar 23 to Mar 24
$212 total
Mar 23 - Mar 24
Total with taxes and fees
9.2/10 Wonderful! (1,000 reviews)
Great area, the hotel seems to be made out of the old casas with tunnel connecting them all and a few patio and small quaint gardens in between them. The staff was very eager to help and nice. Breakfast has a lot of options and very good.
Reviewed on Mar 18, 2026
Hotel Fernando III
San Jose 21 Seville Seville
$229 nightly
The price is $252 total per night from Apr 6 to Apr 7
$252 total
Apr 6 - Apr 7
Total with taxes and fees
9.6/10 Exceptional! (1,487 reviews)
This hotel is lovely. The staff are attentive and helpful. There is a lovely breakfast available and a rooftop bar. It can be a little noisy but not disturbingly so. Excellent place to spend a few nights.
Reviewed on Mar 21, 2026
Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
San Fernando 2 Seville Seville
$583 nightly
The price is $641 total per night from Apr 6 to Apr 7
$641 total
Apr 6 - Apr 7
Total with taxes and fees
9.4/10 Exceptional! (1,000 reviews)
Staff
Reviewed on Feb 27, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Santa Cruz
Royal Alcázar of Seville
Discover a millennium’s worth of royal treasures in this architectural masterpiece in the heart of Seville.
Giralda Tower
Once among the tallest religious monuments in the world, this former minaret is now the eye-catching bell tower to Seville Cathedral.
San Telmo Palace
Tour the striking interior and exterior of a palatial building that serves as the headquarters of the president of the autonomous region of Andalusia.
Things to do
White Villages & Ronda Day Trip from Seville
$93
per adult
94% of travellers recommend
Cathedral & Alcázar of Seville Guided Tour Combo
$39
per adult
92% of travellers recommend
Sevilla Food Tour: Tapas, Wine, History & Traditions
$81
per adult
100% of travellers recommend
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.