Santa Cruz Vacations from $1,117

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Your Santa Cruz Vacation

Booking a Santa Cruz vacation package is a good way to become acquainted with this unique neighborhood. From its must-visit places to its lesser-known treasures, there's a lot to delve into. Some leading nearby attractions to check out during your trip to Santa Cruz include Seville Cathedral, Alcázar and Plaza de España. Whatever your dream Santa Cruz vacation looks like, you can turn it into reality with Expedia.

The Latest Santa Cruz Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Apartamentos Metrópolis Sevilla

Apartamentos Metrópolis Sevilla

3 out of 5
Historical Center
Price was $1,598, price is now $1,117 per person
$1,117
per person
May 11 - May 17
found 2 hours ago
Roundtrip non-stop flight included
Miami (MIA) to Seville (SVQ)
8.8/10 Excellent! (179 reviews)
The location of this apartment is perfect - close to all touristic locations and pretty decent dining options etc.

Reviewed on Dec 23, 2025

CH Apartments Rooftop Terrace

CH Apartments Rooftop Terrace

2.5 out of 5
Historical Center
Price was $1,832, price is now $1,302 per person
$1,302
per person
May 11 - May 17
found 2 hours ago
Roundtrip non-stop flight included
Miami (MIA) to Seville (SVQ)
10/10 Exceptional! (34 reviews)
My boyfriend and I had an amazing experience at this lovely boutique hotel. We absolutely loved every inch of the building. It was clean, stylish and comfortable. The rooftop terrace was also a nice bonus. The location was perfect and makes a great home base for the walkable attractions near by (La Setas, The Cathedral, the Royal Alcazar…) and I would have to agree with all the other reviews that Olga was such a sweet and welcoming host! We would highly recommend this property to anyone wanting to stay in Sevilla.

Reviewed on Jun 10, 2025

Hotel Boutique Corral del Rey by ALUZ Collection

Hotel Boutique Corral del Rey by ALUZ Collection

3 out of 5
Historical Center
Save 100% on your flight
Price was $2,674, price is now $1,923 per person
$1,923
per person
Apr 29 - May 3
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Seville (SVQ)
9.6/10 Exceptional! (89 reviews)
Elegant, comfortable room; incredibly helpful, friendly, and professional staff; and convenient location. Hotel is very well maintained with many unexpected amenities. I’ll stay here again.

Reviewed on Feb 25, 2026

Triana House

Triana House

3 out of 5
Triana
Price was $2,304, price is now $1,662 per person
$1,662
per person
Apr 17 - Apr 19
found 21 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Seville (SVQ)
9.6/10 Exceptional! (84 reviews)
We could not have chosen a better place for our Seville vacation. The location was perfect, staff awesome( fantastic restaurant recommendations), rooms super clean with just the most comfortable bed possible. They even arranged for our airport transfer and tickets to a flamenco show. You’ll love it here.

Reviewed on Dec 30, 2025

Eurostars Sevilla Boutique

Eurostars Sevilla Boutique

4 out of 5
Historical Center
Price was $3,122, price is now $2,282 per person
$2,282
per person
Apr 13 - Apr 19
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Seville (SVQ)
9/10 Wonderful! (503 reviews)
We very much enjoyed our stay here. Excellent location. I would recommend.

Reviewed on Jan 17, 2026

Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
Historical Center

Historical Center

7 out of top 10 points of interest in this area
4.5/5(600 area reviews)

Go on an adventure through the ages when you visit the historical churches, palaces, plazas and mansions of Seville’s ancient heart.

Find hotels in Historical Center

Santa Cruz Hotel Deals

Hotel Fernando III

Hotel Fernando III

4 out of 5
San Jose 21 Seville Seville
Fully refundableReserve now, pay when you stay
$201 nightly
The price is $222 total per night from Mar 9 to Mar 10
$222 total
Mar 9 - Mar 10
Total with taxes and fees
9.6/10 Exceptional! (1,505 reviews)
Beautiful hotel, great breakfast, great location.

Reviewed on Mar 4, 2026

Hotel Fernando III
Las Casas de la Judería, Sevilla Historic City Center

Las Casas de la Judería, Sevilla Historic City Center

4 out of 5
Calle Santa Maria La Blanca 5 Seville Seville
Fully refundableReserve now, pay when you stay
$150 nightly
The price is $165 total per night from Mar 8 to Mar 9
$165 total
Mar 8 - Mar 9
Total with taxes and fees
9.2/10 Wonderful! (1,011 reviews)
What an amazing experience, the history and amazing tunnels under the hotel were fascinating and beautiful. The rooms were clean and the staff was polite and helpful.

Reviewed on Mar 5, 2026

Las Casas de la Judería, Sevilla Historic City Center
Hotel Rey Alfonso X

Hotel Rey Alfonso X

4 out of 5
Calle Ximenez De Enciso, 35 Seville Seville
Fully refundableReserve now, pay when you stay
$203 nightly
The price is $224 total per night from Mar 9 to Mar 10
$224 total
Mar 9 - Mar 10
Total with taxes and fees
9.6/10 Exceptional! (1,138 reviews)
Fantastic location - a short walk to the Alcázar, Seville Cathedral and the Plaza de Espana. The rooms are spacious and the breakfast selection is excellent. The only downside was the air conditioning was okay but not great. I would recommend this hotel.

Reviewed on Mar 5, 2026

Hotel Rey Alfonso X
See all 439 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Discover the most popular places to visit in Santa Cruz

Royal Alcázar showing a church or cathedral and religious elements

Royal Alcázar of Seville

5/5(735 reviews)

Discover a millennium’s worth of royal treasures in this architectural masterpiece in the heart of Seville.

Royal Alcázar of Seville
La Giralda which includes a castle and heritage architecture

Giralda Tower

4.5/5(496 reviews)

Once among the tallest religious monuments in the world, this former minaret is now the eye-catching bell tower to Seville Cathedral.

Giralda Tower
San Telmo Palace which includes heritage architecture

San Telmo Palace

Tour the striking interior and exterior of a palatial building that serves as the headquarters of the president of the autonomous region of Andalusia.

San Telmo Palace

Things to do

Skip the line combo tour to Alcazar & Cathedral of Seville

Cathedral & Alcázar of Seville Guided Tour Combo

$39
per adult
92% of travellers recommend
Cathedral & Alcázar of Seville Guided Tour Combo
Sevilla Food Tour: Tapas, Wine, History & Traditions

Sevilla Food Tour: Tapas, Wine, History & Traditions

$81
per adult
100% of travellers recommend
Sevilla Food Tour: Tapas, Wine, History & Traditions
Flamenco Show at Tablao El Arenal with Drink and Optional Dinner or Tapas

Flamenco Show at Tablao El Arenal with Drink and Optional Dinner or Tapas

$58
per adult
96% of travellers recommend
Flamenco Show at Tablao El Arenal with Drink and Optional Dinner or Tapas
See all activities in Seville

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