
Santa Cruz Vacations from $169
Book a Hotel + Flight or Car together to unlock savings
Your Santa Cruz Vacation
Booking a Santa Cruz vacation package is a good way to become acquainted with this unique neighborhood. From its must-visit places to its lesser-known treasures, there's a lot to delve into. Some leading nearby attractions to check out during your trip to Santa Cruz include Seville Cathedral, Alcázar and Plaza de España. Whatever your dream Santa Cruz vacation looks like, you can turn it into reality with Expedia.
The Latest Santa Cruz Vacation Packages
Price found within the past 48 hours. Click for updated prices.

Exe Gran Hotel Solúcar
Save 100% on your flight
Price was $265, price is now $169 per person
$169
per person
Jul 8 - Jul 11
found 20 hours ago
Roundtrip flight included
Madrid (MAD) to Seville (SVQ)
7.8/10 Good! (447 reviews)
breakfast was good. Only one language cart for entire hotel. Lot of public area but not open for customer to sit, eat and relax.
Reviewed on Apr 10, 2026

Cavalta Boutique Hotel – Small Luxury Hotel
Triana
Save 100% on your flight
Price was $682, price is now $374 per person
$374
per person
Jul 8 - Jul 11
found 21 hours ago
Roundtrip flight included
Madrid (MAD) to Seville (SVQ)
9.8/10 Exceptional! (101 reviews)
Absolutely loved everything about this hotel. Staff are very welcoming and friendly, the food is great - breakfast is exceptional. Would definitely return if we come back to Seville
Reviewed on Apr 11, 2026

Exe Sevilla Macarena
Macarena
Save 100% on your flight
Price was $392, price is now $232 per person
$232
per person
Jul 8 - Jul 11
found 20 hours ago
Roundtrip flight included
Madrid (MAD) to Seville (SVQ)
8/10 Very Good! (1,000 reviews)
Parking needs to be prebooked but the hotel listing on Expedia doesn't tell you. So you have to find public parking which is difficult in Seville
Reviewed on Apr 10, 2026

Hotel Boutique Corral del Rey by ALUZ Collection
Historical Center
Save 100% on your flight
Price was $878, price is now $524 per person
$524
per person
Jul 8 - Jul 11
found 21 hours ago
Roundtrip flight included
Madrid (MAD) to Seville (SVQ)
9.8/10 Exceptional! (125 reviews)
Clean room, nice location, and superb service
Reviewed on Apr 10, 2026

Joya del Casco Boutique Hotel
Historical Center
Save 100% on your flight
Price was $479, price is now $305 per person
$305
per person
Jul 8 - Jul 11
found 20 hours ago
Roundtrip flight included
Madrid (MAD) to Seville (SVQ)
9.6/10 Exceptional! (211 reviews)
Breakfast was fine good selection.
Reviewed on Mar 27, 2026
Where to stay in Santa Cruz
Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz

Historical Center
7 out of top 10 points of interest in this area
4.5/5(606 area reviews)
Go on an adventure through the ages when you visit the historical churches, palaces, plazas and mansions of Seville’s ancient heart.


