Santa Cruz Vacations from $1,961
Book a Hotel + Flight or Car together to unlock savings
Your Santa Cruz Vacation
Booking a Santa Cruz vacation package is a good way to become acquainted with this unique neighborhood. From its must-visit places to its lesser-known treasures, there's a lot to delve into. Some leading nearby attractions to check out during your trip to Santa Cruz include Seville Cathedral, Alcázar and Plaza de España. Whatever your dream Santa Cruz vacation looks like, you can turn it into reality with Expedia.
The Latest Santa Cruz Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Eurostars Sevilla Boutique
Historical Center
Price was $2,673, price is now $1,961 per person
$1,961
per person
May 18 - May 24
found 20 hours ago
Roundtrip non-stop flight included
New York (NYC) to Seville (SVQ)
9/10 Wonderful! (506 reviews)
We very much enjoyed our stay here. Excellent location. I would recommend.
Reviewed on Jan 17, 2026
Apartamentos Metrópolis Sevilla
Historical Center
Price was $3,284, price is now $2,318 per person
$2,318
per person
Apr 18 - Apr 24
found 1 day ago
Roundtrip non-stop flight included
Chicago (CHI) to Seville (SVQ)
8.8/10 Excellent! (179 reviews)
The location of this apartment is perfect - close to all touristic locations and pretty decent dining options etc.
Reviewed on Dec 23, 2025
Hotel Vincci Molviedro Suites Apartments
Historical Center
Price was $4,096, price is now $2,960 per person
$2,960
per person
Apr 18 - Apr 24
found 1 day ago
Roundtrip non-stop flight included
Chicago (CHI) to Seville (SVQ)
9.8/10 Exceptional! (110 reviews)
Best location clean spacious comfortable rooms suites staff behaviours was friendly and supportive
Near transport and shop’s
Nice stay
Reviewed on Jan 19, 2026
Eurostars Al-Ándalus Palace
Bellavista-La Palmera
Price was $2,764, price is now $2,022 per person
$2,022
per person
Apr 18 - Apr 24
found 1 day ago
Roundtrip non-stop flight included
Chicago (CHI) to Seville (SVQ)
8.6/10 Excellent! (1,170 reviews)
Clean rooms, amenities, nice property. Not very helpful staff at reception though.
Reviewed on Feb 24, 2026
Hotel Boutique Triana House
Triana
Price was $4,164, price is now $3,110 per person
$3,110
per person
Apr 19 - Apr 25
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Seville (SVQ)
9.4/10 Exceptional! (27 reviews)
I absolutely LOVED Triana House, I almost want to gate keep it! It's one of the best hotels I've ever stayed in. The interior design was STUNNING! I will definitely stay here next time I'm in Seville.
Reviewed on May 27, 2025
Where to stay in Santa Cruz
Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
Historical Center
8 out of top 10 points of interest in this area
4.5/5(600 area reviews)
Go on an adventure through the ages when you visit the historical churches, palaces, plazas and mansions of Seville’s ancient heart.
Santa Cruz Hotel Deals
Las Casas de la Judería, Sevilla Historic City Center
Calle Santa Maria La Blanca 5 Seville Seville
Fully refundableReserve now, pay when you stay
$192 nightly
The price is $211 total per night from Mar 22 to Mar 23
$211 total
Mar 22 - Mar 23
Total with taxes and fees
9.2/10 Wonderful! (1,006 reviews)
This hotel is a gem. It's like they took old town and stuffed it into hotel. Just take a look at the pictures and you can see it's pretty magical. My room originally was too small for my liking (it literally was only as big as a foot and a half around the bed) but they happily switched me to a more ...
Reviewed on Mar 16, 2026
Hotel Fernando III
San Jose 21 Seville Seville
$213 nightly
The price is $235 total per night from Mar 18 to Mar 19
$235 total
Mar 18 - Mar 19
Total with taxes and fees
9.6/10 Exceptional! (1,493 reviews)
Staff were very friendly and it was really lovely that they sorted some fizz for my friend's birthday. Roof top terrace was really nice and breakfast had lots of choice. Only downsides were the room only had a very small internal window which made it feel a bit claustrophobic. Also a shame for the ...
Reviewed on Mar 17, 2026
Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
San Fernando 2 Seville Seville
Fully refundableReserve now, pay when you stay
$630 nightly
The price is $693 total per night from Apr 14 to Apr 15
$693 total
Apr 14 - Apr 15
Total with taxes and fees
9.4/10 Exceptional! (1,002 reviews)
Staff
Reviewed on Feb 27, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Santa Cruz
Royal Alcázar of Seville
5/5(735 reviews)
Discover a millennium’s worth of royal treasures in this architectural masterpiece in the heart of Seville.
Giralda Tower
4.5/5(496 reviews)
Once among the tallest religious monuments in the world, this former minaret is now the eye-catching bell tower to Seville Cathedral.
San Telmo Palace
Tour the striking interior and exterior of a palatial building that serves as the headquarters of the president of the autonomous region of Andalusia.
Things to do
Cathedral & Alcázar of Seville Guided Tour Combo
$39
per adult
92% of travellers recommend
Sevilla Food Tour: Tapas, Wine, History & Traditions
$81
per adult
100% of travellers recommend
Flamenco Show at Tablao El Arenal with Drink and Optional Dinner or Tapas
$58
per adult
96% of travellers recommend
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.