Find 4 Star Hotels in Colon from $49

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Compare Colon 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Megapolis Hotel Panamá

4.5 star property
San Francisco
8.4 out of 10, Very Good, (1224)
"Great stay "
United States
Mark
$100 nightly
The price is $110
Dec 19 - Dec 20
Total with taxes and fees
Megapolis Hotel Panamá

Las Americas Golden Tower Panama

4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1022)
"Wonderful stay!"
United States
Martha
$139 nightly
The price is $156
Dec 6 - Dec 7
Total with taxes and fees
Las Americas Golden Tower Panama

Marriott Panama Hotel

4.0 star property
Panama City
9.0 out of 10, Wonderful, (1011)
"Rooms are clean, the staff were nice, all the shops were nearby and we just love the Bar selections. "
United States
Ashkuel
$142 nightly
The price is $156
Dec 7 - Dec 8
Total with taxes and fees
Marriott Panama Hotel

Novotel Panama City

4.0 star property
Bella Vista
9.2 out of 10, Wonderful, (1016)
"Room very clean, nice staffs and good location "
United States
Hayden
$90 nightly
The price is $99
Dec 9 - Dec 10
Total with taxes and fees
Novotel Panama City

Studio Coliving

4.5 star property
Bella Vista
8.0 out of 10, Very Good, (567)
"The staff was friendly and always helpful when I had requests. The room was"
United States
Toni-Q
$44 nightly
The price is $49
Nov 26 - Nov 27
Total with taxes and fees
Studio Coliving

Decapolis Hotel Panama City

4.0 star property
San Francisco
8.6 out of 10, Excellent, (1408)
"Good place for a short stay"
United States
carlos
$76 nightly
The price is $84
Nov 30 - Dec 1
Total with taxes and fees
Decapolis Hotel Panama City

Ramada Plaza by Wyndham Panama Punta Pacifica

4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1096)
"Good location, Spotless room, friendly and helpful staff"
United States
JOSE JULIAN
$99 nightly
The price is $109
Dec 7 - Dec 8
Total with taxes and fees
Ramada Plaza by Wyndham Panama Punta Pacifica

American Trade Hotel

4.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (591)
"Excellent service and great rooms on a beautiful and historical building"
Canada
Manuel
$232 nightly
The price is $257
Dec 2 - Dec 3
Total with taxes and fees
American Trade Hotel

Sheraton Grand Panama

4.0 star property
San Francisco
8.6 out of 10, Excellent, (980)
"Centrally located and friendly staff "
United States
Julio
$128 nightly
The price is $140
Nov 30 - Dec 1
Total with taxes and fees
Sheraton Grand Panama

Waymore Hotel Spa & Casino

4.0 star property
Bella Vista
9.0 out of 10, Wonderful, (598)
"Overall the hotel was splendid - clean, quiet, very convenient, amenities nearby, great food - and was a pleasant place to rest for a few days as we explored the city."
Canada
Daina
$90 nightly
The price is $99
Dec 10 - Dec 11
Total with taxes and fees
Waymore Hotel Spa & Casino

Courtyard by Marriott Panama Metromall

4.0 star property
Cerro Viento
8.8 out of 10, Excellent, (1011)
"It was very clean good friendly staff good food i really love there goong back next time "
United States
Sylvester Keith
$110 nightly
The price is $121
Dec 18 - Dec 19
Total with taxes and fees
Courtyard by Marriott Panama Metromall

Holiday Inn Panama Distrito Financiero by IHG

4.0 star property
Bella Vista
8.8 out of 10, Excellent, (1010)
"Clean room, staff in the restaurant and housekeeping very friendly"
United States
Carmen
$71 nightly
The price is $78
Dec 7 - Dec 8
Total with taxes and fees
Holiday Inn Panama Distrito Financiero by IHG

Central Hotel Panama Casco Viejo

4.0 star property
Casco Viejo
9.0 out of 10, Wonderful, (1008)
"Hotel was beautiful, staff was very helpful and accommodating. We had the pool two separate days to ourselves. Breakfadt was very good. Staff was very helpful getting us drivers wherever we wanted to go in the city."
United States
MICHELE
$232 nightly
The price is $255
Dec 3 - Dec 4
Total with taxes and fees
Central Hotel Panama Casco Viejo

Courtyard by Marriott Panama Multiplaza Mall

4.0 star property
San Francisco
8.8 out of 10, Excellent, (1006)
"Perfect stay "
United States
pedro
$118 nightly
The price is $130
Dec 6 - Dec 7
Total with taxes and fees
Courtyard by Marriott Panama Multiplaza Mall

Residence Inn by Marriott Panama City

4.0 star property
San Francisco
9.0 out of 10, Wonderful, (532)
"Amazing hotel amazing view service great location perfect "
United States
Melissa
$144 nightly
The price is $158
Dec 5 - Dec 6
Total with taxes and fees
Residence Inn by Marriott Panama City

Hyatt Regency Panama City

4.5 star property
Bella Vista
10.0 out of 10, Exceptional, (113)
"Great stay for a birthday celebration "
United States
Carmenzina
$135 nightly
The price is $149
Nov 28 - Nov 29
Total with taxes and fees
Hyatt Regency Panama City

Hotel San Felipe

4.0 star property
Casco Viejo
9.4 out of 10, Exceptional, (234)
"Really nice staff and property is in amazing location "
United States
Michael
$122 nightly
The price is $134
Dec 1 - Dec 2
Total with taxes and fees
Hotel San Felipe

Hotel La Compañía Casco Antiguo

4.5 star property
Casco Viejo
9.8 out of 10, Exceptional, (251)
"Many shops and restaurants nearby and the hotel is located in a beautiful area "
United States
Jerry
$310 nightly
The price is $341
Dec 4 - Dec 5
Total with taxes and fees
Hotel La Compañía Casco Antiguo

Radisson Hotel Panama Canal

4.5 star property
Amador
8.4 out of 10, Very Good, (1010)
"Love the location and convenience "
United States
Patricia
$70 nightly
The price is $77
Dec 23 - Dec 24
Total with taxes and fees
Radisson Hotel Panama Canal

Radisson Colon 2,000 Hotel & Casino

4.0 star property
Barrio Sur
8.2 out of 10, Very Good, (809)
"Staff was great room was clean"
United States
Bridgett
$88 nightly
The price is $97
Dec 13 - Dec 14
Total with taxes and fees
Radisson Colon 2,000 Hotel & Casino
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Explore similar 5-star hotels

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Colon

Explore the colorful Zona Libre free trade zone for duty-free shopping and visit the historic Colon 2000 cruise port. Discover Panama's colonial history at Fort San Lorenzo, located on the Caribbean coast outside the city.

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Top Colon Hotel Reviews

Find out more about Colon

The preparation of any much-needed vacation gets started with selecting a location. Colon has become a popular choice with travelers because it offers so much. Location is everything, but that accounts for more than the town you are flying into. Now that you have got a feel for the town, it is time you to get to know your new digs.

Accommodations as Stunning as the City

Colon saw its fair share of visitors this past year. Expedia's comment section includes comments that can help you narrow down your pick. The resorts found here aim to make your stay as pleasant as your evenings hanging out in Colon. These hotels strive to make their facilities and grounds welcoming from the minute you step out of your car. You will never need to go far to find a delicious snack, to sustain your workout routine, or for an energizing plunge during your visit with all they offer.

Rooms have been fashioned to keep you as cozy as possible, with amenities like ultra-comfortable bedding, and in-room tea or coffee, and designer bathroom products. So, sit back and unwind. Moreover, if you find that you're need of something more, you can be confident the staff will try their hardest to ensure you stay pleased during your time. These hotels are so lovely that you'll regret the day you have to check-out.

Book a 4-Star Hotel in Colon Today!

Your holiday to Colon should be one that you'll remember for years to come, and booking a 4-star hotel can help make those memories nothing but incredible. With Expedia, you will get affordable rates on first-class accommodations to take your trip to the next level.

Frequently asked questions

What are the best 4-star hotels in Colon?
If you're seeking high-quality comfort and plenty of amenities during your Colon escape, check out Radisson Colon 2,000 Hotel & Casino. This 4-star hotel comes with a steam room and concierge services. Melia Panama Canal also gets great reviews from Expedia travelers. A tennis court and a terrace are among its conveniences.
How much does it cost to stay in a 4-star hotel in Colon?
Expedia can help you quickly find the perfect 4-star hotel for your getaway in Colon. Use our filter tool to fine-tune your search by things like price, conveniences and property star rating and get access to fabulous deals in a few clicks.

  • Search for the lowest price from $126

What's the difference between 5-star and 4-star hotels in Colon?
If you decide to book a stay at a 4-star hotel in Colon, you'll usually find loads of amenities to ensure you're comfortable, such as a restaurant, gym and pool. You can enjoy excellent service and upmarket surroundings. Opt for a 5-star hotel and you'll get a few extra perks — think around-the-clock concierge, on-site spas and opulent turndown services. You're likely to get additional amenities and first-class services at a 5-star stay, but both are awesome options for luxury travelers.

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