Cheap Flights from San Francisco (SFO) to Colon (ONX)

Popular airlines from San Francisco Intl. Airport (SFO) to Colon (ONX-Enrique Adolfo Jimenez)

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Frequently asked questions

How much does a flight from San Francisco Intl. Airport (SFO) to Colon (ONX-Enrique Adolfo Jimenez) cost?
Grab a cheap one-way flight or cheap return flight from San Francisco Intl. Airport (SFO) to Colon (ONX-Enrique Adolfo Jimenez) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from San Francisco Intl. Airport (SFO) to Colon (ONX-Enrique Adolfo Jimenez)?
The cheapest month to fly from SFO to ONX is , when demand is low. Off-peak season is often when you'll find lower airfares between these airports.
What is the cheapest airline that flies from San Francisco Intl. Airport (SFO) to Colon (ONX-Enrique Adolfo Jimenez)?
Expedia's filter tool lets you easily compare different airlines, travel time and fares all in one place. Tailor the search to your trip, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest SFO to ONX flight.
How many flights per day from San Francisco Intl. Airport (SFO) to Colon (ONX-Enrique Adolfo Jimenez)?
Direct flights from San Francisco Intl. Airport (SFO) to Colon (ONX-Enrique Adolfo Jimenez) aren't available daily, so you'll need to take a flight with a layover. Explore your options with our filter tool. Enter your dates and click on either "1 Stop" or "2+ Stops."
What day of the week has the most flights from SFO to ONX?
Usually you'll find the most flight options available on a Friday. Tuesdays are often the quietest.* But this can vary depending on the time of year, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from San Francisco Intl. Airport (SFO) to Colon (ONX-Enrique Adolfo Jimenez)?
To reach Colon (ONX-Enrique Adolfo Jimenez) on schedule, pick a flight that takes off from San Francisco Intl. Airport (SFO) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Colon from San Francisco Intl. Airport (SFO)?
Compare your flight options from San Francisco Intl. Airport (SFO) to Tocumen Intl. Airport (PTY). This is the only Colon airport you can jet into if you're taking a direct flight.
Is it cheaper to buy a plane ticket from San Francisco Intl. Airport (SFO) to Colon (ONX-Enrique Adolfo Jimenez) last-minute?
Booking your plane ticket from SFO to ONX just before your trip is generally more expensive. But if there's some wiggle room with your departure times and dates, you could bag a cheap last-minute fare.
Is it cheaper to book a SFO to ONX flight and hotel package?
Booking a SFO to ONX flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip in one place. Select from our impressive range of accommodations and then add car rentals, activities and flights to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from San Francisco Intl. Airport (SFO) to Colon (ONX-Enrique Adolfo Jimenez)?
If you reserved your SFO to ONX flight in the last 24 hours, you may be able to modify or cancel it without fees. Depending on the airline and the type of fare you have, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal for further details.

Travel information

Origin airport
San Francisco Intl.
Destination airport
Enrique Adolfo Jimenez
Distance
3283 mi

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San Francisco to Colon Flights

The cheapest times to fly from San Francisco to Colon

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from San Francisco to Colon are during the month of . You can find some of the cheapest flights from San Francisco to Colon with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from San Francisco to Colon

Sunday is one of the best days to book for cheap flights from San Francisco to Colon: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from San Francisco to Colon

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from San Francisco to Colon in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap San Francisco to Colon flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your San Francisco to Colon airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

San Francisco to Colon Flights

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*Available to One Key members.