Find luxury hotels in Cairo, MO

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Top Cairo Luxury Hotels

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Recommended hotels in Cairo

Comfort Inn & Suites Moberly

2.5 star property
Moberly
8.4 out of 10, Very Good, (422)
"Good breakfast. Clean room's "
United States
David
$89 nightly
The price is $100
Dec 7 - Dec 8
Total with taxes and fees
Comfort Inn & Suites Moberly

Simple Rewards Inn Shelbina

2.0 star property
Shelbina
8.2 out of 10, Very Good, (153)
"Simple but great for a good nights sleep. "
United States
Jan
$81 nightly
The price is $89
Dec 23 - Dec 24
Total with taxes and fees
Simple Rewards Inn Shelbina

Super 8 by Wyndham Moberly MO

2.0 star property
Moberly
8.2 out of 10, Very Good, (812)
"Excellent stay; thank you!"
United States
Scarlett Lynn
$64 nightly
The price is $72
Jan 4 - Jan 5, 2026
Total with taxes and fees
Super 8 by Wyndham Moberly MO

OYO Travelier Motel

2.5 star property
Macon
7.6 out of 10, Good, (383)
"Room was great service was awesome "
United States
Dara
$70 nightly
The price is $75
Dec 7 - Dec 8
Total with taxes and fees
OYO Travelier Motel

Briggs Convenience Haven, Briggs Convenience Haven

2.0 star property
Macon
10.0 out of 10, Exceptional, (4)
"Clean house with very comfortable beds. "
United States
Paul H.
$264 nightly
The price is $264
Dec 30 - Dec 31
Total with taxes and fees
Briggs Convenience Haven, Briggs Convenience Haven

Americas Best Value Inn & Suites Macon at Sunset Dr

2.0 star property
Macon
6.6 out of 10, (333)
"Was clean had comfortable bed. Older motel but in decent shape. Would stay there again "
United States
Paul
$65 nightly
The price is $69
Jan 1 - Jan 2, 2026
Total with taxes and fees
Americas Best Value Inn & Suites Macon at Sunset Dr

Teal Nest - at The Lodges of Long Branch

Bevier Township
10.0 out of 10, Exceptional, (2)
"Great place to stay and relax. Great Italian Food close by -Ugo;s. Will stay here again next year"
United States
Vincent H.
$165 nightly
The price is $170
Dec 8 - Dec 9
Total with taxes and fees
Teal Nest - at The Lodges of Long Branch

Unwind on Vine

Macon
9.4 out of 10, Exceptional, (22)
"The house was very nice and clean. Will stay again!!"
United States
Ashley G.
$160 nightly
The price is $160
Dec 7 - Dec 8
Total with taxes and fees
Unwind on Vine

Mallard Cottage - At the Lodges of Long Branch

Bevier Township
$269 nightly
The price is $279
Dec 8 - Dec 9
Total with taxes and fees
Mallard Cottage - At the Lodges of Long Branch

Blue Heron Hut - At the Lodges of Long Branch

Bevier Township
$246 nightly
The price is $256
Dec 8 - Dec 9
Total with taxes and fees
Blue Heron Hut - At the Lodges of Long Branch
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Cairo Hotel Reviews

Frequently asked questions

Are you looking for a luxury hotel for your stay in Cairo?
Amenities are an important consideration when you plan a trip, so we make it easy to get what you want to make your stay relaxing and comfortable. If you want a posh hotel with fine dining, a spa, or several swimming pools, Expedia can help you find the best luxury hotel experience that Cairo offers.
When can I expect good weather in Cairo?
Planning for the weather is a good way to make your trip to Cairo relaxing and enjoyable, especially when you're splurging. The hottest months are usually July and August with an average temp of 74°F, while the coldest months are January and February with an average of 35°F. The snowiest months in Cairo are January, November, February, and December, with each month seeing an average of 5 inches of snowfall.
What's there to see and do in Cairo?
Experience Cairo and visit Heritage Hills Golf Course, Magic City Line Mini Train, and Maples Repertory Theatre. If you have a bit of extra time while you're in the area, you might want to check out Long Branch State Park and Union Covered Bridge States Historic Site.

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