Find all hotels by Independent in Cairo, MO from $80

    price find illustration

    Upfront pricing

    Our total price for your stay includes taxes and fees
    deals illustration

    Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
    Learn about One Key
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Jul 14 - Jul 15
Tomorrow
Jul 15 - Jul 16
This weekend
Jul 18 - Jul 20
Next weekend
Jul 25 - Jul 27

Compare rooms and suites by Independent in Cairo with rates, reviews, and availability. Most hotels are fully refundable.

Simple Rewards Inn Shelbina
Two single beds with dark headboards and matching bedding, a bedside table, and a framed picture adorn this cozy space.

Simple Rewards Inn Shelbina

2.0 star property
8.2 out of 10, Very Good, (143)
"Small motel, very clean and quiet. Only thing that we would have enjoyed was a coffee maker in or room. "
$73 nightly
The price is $80
Jul 27 - Jul 28
Total includes taxes and fees
Simple Rewards Inn Shelbina
Unwind on Vine
Kitchen features a stove, oven, microwave, and sink, with a dining area nearby.

Unwind on Vine

9.0 out of 10, Wonderful, (10)
"Extremely happy with our visit. No issues at all. "
$160 nightly
The price is $160
Jul 18 - Jul 19
Total includes taxes and fees
Unwind on Vine
Historic Clark Cabin w/ Deck & Fishing Pond Access
Relax in comfort with a spacious living area featuring a plush sectional sofa and a well-equipped kitchen with modern amenities.

Historic Clark Cabin w/ Deck & Fishing Pond Access

9.0 out of 10, Wonderful, (9)
"The property was quite and peaceful. The house was clean plenty of room for family and friends! We enjoyed the sunroom and porch and of course the pond"
Historic Clark Cabin w/ Deck & Fishing Pond Access
R&R Guest House- Renovated Downtown Gem, Patio
Fully equipped kitchen with a range hood, double oven, and gas stove, sink, and ample countertop space.

R&R Guest House- Renovated Downtown Gem, Patio

7.0 out of 10, Good, (2)
"Such a cute, clean, spacious loft. The pictures do not do it justice. We booked it for our kids coming into town for the weekend. We would definitely book it again. "
R&R Guest House- Renovated Downtown Gem, Patio
'Grace Place' Clark House on Farm: Shared Hot Tub!
Fully equipped kitchen with refrigerator, microwave, oven, and sink.

'Grace Place' Clark House on Farm: Shared Hot Tub!

10.0 out of 10, Exceptional, (26)
"Was so relaxing loved the animals and the pool was amazing"
'Grace Place' Clark House on Farm: Shared Hot Tub!
Peaceful Lakeside Getaway with Private Dock surrounded with Serene Wilderness
Relax on the elevated deck overlooking the tranquil water, where a fire feature and dock await.

Peaceful Lakeside Getaway with Private Dock surrounded with Serene Wilderness

10.0 out of 10, Exceptional, (16)
"Beautiful place to stay inside and out. It was fun watching the wildlife. "
Peaceful Lakeside Getaway with Private Dock surrounded with Serene Wilderness
Spacious 12-bedroom 10-Bath Cedar accented lodge in Picturesque Macon Missouri
Cozy cabin with a prominent chimney and covered porch, offering a warm and inviting atmosphere.

Spacious 12-bedroom 10-Bath Cedar accented lodge in Picturesque Macon Missouri

10.0 out of 10, Exceptional, (2)
"Cimfortable and clean. Ideal setup for our reunion."
Spacious 12-bedroom 10-Bath Cedar accented lodge in Picturesque Macon Missouri
Briggs Convenience Haven, Briggs Convenience Haven
Fridge, microwave, oven, stovetop

Briggs Convenience Haven, Briggs Convenience Haven

2.0 star property
10.0 out of 10, Exceptional, (2)
"The host was extremely friendly and helpful. The house was beautiful and located in an amazing area. Overall the stay was excellent! "
$264 nightly
The price is $264
Jul 28 - Jul 29
Total includes taxes and fees
Briggs Convenience Haven, Briggs Convenience Haven
Charming Paris Home w/ Porch: Hunt + Unwind!
Relax in a serene outdoor space with a wooden deck and a view of the surrounding woods.

Charming Paris Home w/ Porch: Hunt + Unwind!

10.0 out of 10, Exceptional, (1)
"We absolutely loved our stay! Can’t wait to come back next year!"
Charming Paris Home w/ Porch: Hunt + Unwind!
The Sundae Cottage - A Missouri Sweet Spot , beautiful views, secluded 🌻
Enjoy a serene view of the lush landscape from the comfort of your room, with a large dining table and a single chair by the window.

The Sundae Cottage - A Missouri Sweet Spot , beautiful views, secluded 🌻

10.0 out of 10, Exceptional, (43)
"Perfect place to stay, we enjoyed our stay, very friendly host, property was beautiful !"
The Sundae Cottage - A Missouri Sweet Spot , beautiful views, secluded 🌻
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free