Title: Visit Eastern Macedonia and Thrace: 2026 Travel Guide for Eastern Macedonia and Thrace, Greece | Expedia.com [Eastern Macedonia and Thrace Hotels](https://expedia.com/Destinations-In-Eastern-Macedonia-And-Thrace.d6054804.Hotel-Destinations)[Vacation Rentals in Eastern Macedonia and Thrace](https://expedia.com/Destinations-In-Eastern-Macedonia-And-Thrace.d6054804.Vacation-Rental-Destinations)[Eastern Macedonia and Thrace Flights](https://expedia.com/Destinations-In-Eastern-Macedonia-And-Thrace.d6054804.Flight-Destinations)[Things to do in Eastern Macedonia and Thrace](https://expedia.com/Things-To-Do-In-Eastern-Macedonia-And-Thrace.d6054804.Travel-Guide-Activities)[Car Rentals in Eastern Macedonia and Thrace](https://expedia.com/Destinations-In-Eastern-Macedonia-And-Thrace.d6054804.Car-Rental-Destinations)[Eastern Macedonia and Thrace Vacations](https://expedia.com/Eastern-Macedonia-And-Thrace.d6054804.Destination-Travel-Guides) # Eastern Macedonia and Thrace ## Greece ![Byzantine Walls showing a coastal town, general coastal views and heritage architecture](https://images.trvl-media.com/place/6290775/aee3815d-97e8-4188-8c1b-32caa6d71e72.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Byzantine Walls showing a coastal town, general coastal views and heritage architecture](https://images.trvl-media.com/place/6290775/aee3815d-97e8-4188-8c1b-32caa6d71e72.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Church of Saint Demetrius showing heritage architecture, religious aspects and outdoor art](https://images.trvl-media.com/place/6105586/59240ffd-292d-4048-aeba-67cd10e8dd1a.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Museum of Byzantine Culture showing outdoor art](https://images.trvl-media.com/place/6105614/8b6c927c-a3c6-49a3-bdd8-8c293af81ce7.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Byzantine Walls showing a castle, a city and night scenes](https://images.trvl-media.com/place/6290775/863e7087-ad17-49e4-9d74-f4a2cac9d482.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ### Popular cities in Eastern Macedonia and Thrace [Thasos Known for Islands, Water skiing and Safaris ](https://expedia.com/Thasos.dx6142877) Come to quaint Thasos and enjoy its waterskiing, safaris, and mountain views. ## Reasons to visit - Saliara Beach - Chrisi Akti Beach [Explore City](https://expedia.com/Thasos.dx6142877)[Find Hotels](https://expedia.com/Thasos-Hotels.d6142877.Travel-Guide-Hotels) [Alexandroupoli Known for Casinos, Cafes and Museums ](https://expedia.com/Alexandroupoli.dx473) Escape to Alexandroupoli! Enjoy its casinos, cafes, and oceanfront. [Explore City](https://expedia.com/Alexandroupoli.dx473)[Find Hotels](https://expedia.com/Alexandroupoli-Hotels.d473.Travel-Guide-Hotels) [Kavala Known for Sea, Ports and Historical ](https://expedia.com/Kavala.dx1959) Kavala awaits: its oceanfront, cafes, beaches, and more! [Explore City](https://expedia.com/Kavala.dx1959)[Find Hotels](https://expedia.com/Kavala-Hotels.d1959.Travel-Guide-Hotels) [Xanthi Known for Small town, Hiking and Forests ](https://expedia.com/Xanthi.dx6123654) Experience quaint Xanthi: its parks, hiking, horseback riding, and more! [Explore City](https://expedia.com/Xanthi.dx6123654)[Find Hotels](https://expedia.com/Xanthi-Hotels.d6123654.Travel-Guide-Hotels) [Samothrace Known for Islands, Beaches and Small town ](https://expedia.com/Samothrace.dx6322125) Get away to quaint Samothrace! Enjoy the beaches, island views, and waterfalls. [Explore City](https://expedia.com/Samothrace.dx6322125)[Find Hotels](https://expedia.com/Samothrace-Hotels.d6322125.Travel-Guide-Hotels) [Drama Known for Coffee, Opera and Archaeology and anthropology ](https://expedia.com/Drama.dx6060333) Explore upscale Drama: its coffee, opera, theater, and more! [Explore City](https://expedia.com/Drama.dx6060333)[Find Hotels](https://expedia.com/Drama-Hotels.d6060333.Travel-Guide-Hotels) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. 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