Title: Visit Esquipulas: 2026 Travel Guide for Esquipulas, Matagalpa Department | Expedia.com [Hotels in Esquipulas](https://expedia.com/Esquipulas-Hotels.d662833757924794368.Travel-Guide-Hotels)[Vacation Rentals in Esquipulas](https://expedia.com/Esquipulas-Vacation-Rentals.d662833757924794368.Travel-Guide-VacationRentals)[Flights to Esquipulas](https://expedia.com/Cheap-Flights-To-Esquipulas.d662833757924794368.Travel-Guide-Flights)[Car Rentals in Esquipulas](https://expedia.com/Car-Rentals-In-Esquipulas.d662833757924794368.Car-Rental-Guide)[Esquipulas Vacation Packages](https://expedia.com/Esquipulas.d662833757924794368.Destination-Travel-Guides) # Esquipulas ## Travel Guide ## Visit Esquipulas - Esquipulas Hotel Deals - Vacation Rentals in Esquipulas ![Montebrisa Boutique B&B](https://images.trvl-media.com/lodging/37000000/36750000/36746300/36746289/485f5871_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Montebrisa Boutique B&B Del Parque Morazán, 3 Cuadras al Este Matagalpa Matagalpa $90 nightly $104 total Mar 25 - Mar 26 Total with taxes and fees Stay at this B&B in Matagalpa. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Centro Cultural "Héroes y Mártires" and Guanuca Cultural ... 9/10 Wonderful! (46 reviews) Beautiful place. Clean room. Staff friendly. We will comeback. Reviewed on Mar 15, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F25%2F2026&endDate=3%2F26%2F2026&selected=36746289&PinnedHotelID=36746289&HadPinnedHotel=true®ionId=662833757924794368) ![Vera Eco-Resort](https://images.trvl-media.com/lodging/112000000/111260000/111250700/111250683/75b5851e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Vera Eco-Resort Vera Eco-Resort San Ramon Matagalpa $78 nightly $91 total Apr 1 - Apr 2 Total with taxes and fees Stay at this resort in San Ramon. Enjoy free breakfast, free WiFi, and free parking. Popular attraction Guanuca Cultural Center is located nearby. 8/10 Very Good! (4 reviews) This place is amazing!!!! The staff is super friendly and the location is beautiful Reviewed on Nov 20, 2025 [](https://expedia.com/Hotel-Search?startDate=4%2F1%2F2026&endDate=4%2F2%2F2026&selected=111250683&PinnedHotelID=111250683&HadPinnedHotel=true®ionId=662833757924794368) ![Hotel Vizcaino ](https://images.trvl-media.com/lodging/125000000/124520000/124519000/124518912/4f0237c3_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Vizcaino Iglesia de Guadalupe 1 1/2 al sur Matagalpa matagalpa $54 nightly $63 total Mar 25 - Mar 26 Total with taxes and fees Stay at this B&B in Matagalpa. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Popular attractions Guanuca Cultural Center and Centro Cultural "Héroes ... 8/10 Very Good! (1 review) The room was clean and well appointed. Nice balcony to sit on. Friendly staff. Reviewed on Feb 23, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F25%2F2026&endDate=3%2F26%2F2026&selected=124518912&PinnedHotelID=124518912&HadPinnedHotel=true®ionId=662833757924794368) [See all 15 properties in Esquipulas](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=3%2F25%2F2026&endDate=3%2F26%2F2026®ionId=662833757924794368) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Casa Sunshine](https://images.trvl-media.com/lodging/95000000/94780000/94777300/94777286/7f7d3b7d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Casa Sunshine Matagalpa Matagalpa Stay at this apartment in Matagalpa. Enjoy laundry facilities and air conditioning. Popular attractions Casa Museo Comandante Carlos Fonseca and National Coffee ... 6/10 (1 review) The air conditioning was not working. But the host was very nice and was able to accommodate our late arrival Reviewed on Mar 17, 2026 [](https://expedia.com/Matagalpa-Hotels-Casa-Sunshine.h94777286.Hotel-Information) ![A Thousand Flowers from Pacsila: CASA TEJAS](https://images.trvl-media.com/lodging/114000000/113650000/113647700/113647605/f9944c01_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### A Thousand Flowers from Pacsila: CASA TEJAS Matagalpa Matagalpa Stay at this vacation home in Matagalpa. Enjoy laundry facilities. Popular attractions Cathedral San Pedro and Guanuca Cultural Center are located nearby. [](https://expedia.com/Matagalpa-Hotels-Vrbo-Property.h113647605.Hotel-Information) [See all properties in Esquipulas](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=662833757924794368&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Esquipulas hotel availability [Tonight ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=662833757924794368&startDate=2026-03-24&endDate=2026-03-25)[Mar 24 - Mar 25](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=662833757924794368&startDate=2026-03-24&endDate=2026-03-25) [Tomorrow night ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=662833757924794368&startDate=2026-03-25&endDate=2026-03-26)[Mar 25 - Mar 26](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=662833757924794368&startDate=2026-03-25&endDate=2026-03-26) [This weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=662833757924794368&startDate=3%2F27%2F2026&endDate=3%2F29%2F2026)[Mar 27 - Mar 29](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=662833757924794368&startDate=3%2F27%2F2026&endDate=3%2F29%2F2026) [Next weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=662833757924794368&startDate=4%2F3%2F2026&endDate=4%2F5%2F2026)[Apr 3 - Apr 5](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=662833757924794368&startDate=4%2F3%2F2026&endDate=4%2F5%2F2026) ## Cities near Esquipulas ![Latin tourist exploring a waterfall in Matagalpa, Nicaragua](https://images.trvl-media.com/place/6053701/7932a73c-8afb-40a6-b0c9-df89a35b858b.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Matagalpa ![Iglesia Santiago Apostol - Boaco, Nicaragua](https://images.trvl-media.com/place/6351042/992d45ab-ce8d-4d10-a797-52bc2b7c7670.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Boaco ![Cityscape of Matagalpa city on mountain](https://images.trvl-media.com/place/662833867258114048/7c3749ac-5529-463e-a39e-69a44025a210.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Muy Muy ## Explore a world of travel with Expedia - Lodging - Cars - [San Dionisio Hotels ](https://www.expedia.com/San-Dionisio-Hotels.d662833753613049856.Travel-Guide-Hotels) - [Car rentals near San Dionisio ](https://www.expedia.com/Car-Rentals-In-San-Dionisio.d662833753613049856.Car-Rental-Guide) - Cities near Esquipulas - Places of interest [Matagalpa](https://expedia.com/Matagalpa.dx6053701)[Boaco](https://expedia.com/Boaco.dx6351042)[Terrabona](https://expedia.com/Terrabona.dx662833748170940416)[San Dionisio](https://expedia.com/San-Dionisio.dx662833753613049856)[Muy Muy](https://expedia.com/Muy-Muy.dx662833770925436928)[San José de Los Remates](https://expedia.com/San-Jose-De-Los-Remates.dx662833844836732928) - [Ruben Dario Museum ](https://expedia.com/Ruben-Dario-Museum-Ciudad-Dario.d553248621532964561.Vacation-Attraction) - [Cerro Apante Natural Reserve ](https://expedia.com/Cerro-Apante-Natural-Reserve-Matagalpa.d553248621532962631.Vacation-Attraction) - [Guanuca Cultural Center ](https://expedia.com/Guanuca-Cultural-Center-Matagalpa.d553248621532963945.Vacation-Attraction) - [El Castillo del Cacao ](https://expedia.com/El-Castillo-Del-Cacao-Matagalpa.d553248621592397554.Vacation-Attraction) - [Parque Morazan ](https://expedia.com/Parque-Morazan-Matagalpa.d553248621583807764.Vacation-Attraction) - [Cathedral San Pedro ](https://expedia.com/Cathedral-San-Pedro-Matagalpa.d553248621532964569.Vacation-Attraction) - [Molaguina Church ](https://expedia.com/Molaguina-Church-Matagalpa.d553248621532964566.Vacation-Attraction) - [San Jose Church ](https://expedia.com/San-Jose-Church-Matagalpa.d553248621532964567.Vacation-Attraction) - [Nuestra Senora del Perpetuo Socorro Parish ](https://expedia.com/Nuestra-Senora-Del-Perpetuo-Socorro-Parish-Boaco.d553248621592397553.Vacation-Attraction) - [National Coffee Museum ](https://expedia.com/National-Coffee-Museum-Matagalpa.d553248621532964571.Vacation-Attraction) - [Parroquia de Nuestra Señora del Perpetuo Socorro ](https://expedia.com/Parroquia-De-Nuestra-Senora-Del-Perpetuo-Socorro-Boaco.d553248621532964558.Vacation-Attraction) - [Casa Museo Comandante Carlos Fonseca ](https://expedia.com/Casa-Museo-Comandante-Carlos-Fonseca-Matagalpa.d553248621532964568.Vacation-Attraction) - [Foreigners Cemetery ](https://expedia.com/Foreigners-Cemetery-Matagalpa.d553248621532964565.Vacation-Attraction) - [Parque El Cerrito del Faro ](https://expedia.com/Parque-El-Cerrito-Del-Faro-Boaco.d553248621532964557.Vacation-Attraction) - [Matagalpa Spanish School ](https://expedia.com/Matagalpa-Spanish-School-Matagalpa.d553248621562621259.Vacation-Attraction)