Title: Fullsize South America Car Rentals | Expedia.com ![](https://images.trvl-media.com/place/6140917/ba4ee8aa-2da1-4310-8a44-1015fb6e7a3d.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Fullsize Car Rental Companies in South America ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=CTG_SPRING_PROMO_6023117) ## Frequently Asked Questions | Fullsize Car Rentals in South America ### Where can I rent Fullsize cars in South America? In South America, multiple suppliers are offering Fullsize cars at an excellent price. Compare locations and providers on Expedia.com to find the best deal for what you’re looking for. The airport location generally has the largest selection to choose from. ### How can I find the best deals on Fullsize car rentals in South America? You can see all the available offers on Fullsize rentals in South America and then compare prices from various providers and pick-up locations. Prices may vary depending on which supplier you choose, the pick-up location, and the dates of your trip. You can also browse deals for other car types on our [car rentals in South America](https://www.expedia.com/Destinations-In-South America.d6023117.Car-Rental-Destinations) page. ### What is the cancellation policy for car rentals in South America? Each car rental deal has its own cancellation policy. Some bookings are free to cancel while most pre-paid bookings are non-refundable. We recommend filtering by “free cancellation” to see the most flexible options. ### Why is Expedia.com the best place to book a car rental? Here at Expedia.com, we go the extra mile, so you can too! You’ll select your Fullsize car rental in South America from a large inventory and get the best deals available from suppliers in the area. Whether you’re looking for a short or [long term car rental](https://www.expedia.com/lp/b/car-rental/long-term) we’ve got you covered. You’ll get rewards back from every booking, and can customize your entire trip itinerary, all in one place. We have the best deals, not only on car rentals but also on [hotels in South America](https://www.expedia.com/Destinations-In-South America.d6023117.Hotel-Destinations). Bundle them into one, and you’ll get a [vacation package in South America](https://www.expedia.com/South America.d6023117.Destination-Travel-Guides) for less. ## Fullsize Car Rental Information | Car type: | Fullsize | | ------------------------------------------------- | ------------------------------------------------------------------------------------------------------- | | Price: | | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.com/ground-transfers?rfrr=car.table.AirportTransportation) | | From popular domestic and international airports: | [Airport Car Rentals](https://www.expedia.com/lp/b/car-rental/airport) | ### Experience new places with Expedia See our world of travel options ### Expedia's Latest Trends Hotels - [All-inclusive Resorts in Peru](https://expedia.com/Destinations-In-Peru-All-Inclusive-Hotel.0-0-d144-tAllinclusiveHotel.Hotel-Filter-Destinations) - [All-inclusive Resorts in Rio de Janeiro State](https://expedia.com/Destinations-In-Rio-De-Janeiro-State-All-Inclusive-Hotel.0-0-d6052641-tAllinclusiveHotel.Hotel-Filter-Destinations) - [All-inclusive Resorts in Colombia](https://expedia.com/Destinations-In-Colombia-All-Inclusive-Hotel.0-0-d38-tAllinclusiveHotel.Hotel-Filter-Destinations) - [All-inclusive Resorts in Brazil](https://expedia.com/Destinations-In-Brazil-All-Inclusive-Hotel.0-0-d23-tAllinclusiveHotel.Hotel-Filter-Destinations) Flights - [Flights to Chile](https://expedia.com/Destinations-In-Chile.d36.Flight-Destinations) - [Flights to Paraguay](https://expedia.com/Destinations-In-Paraguay.d143.Flight-Destinations) - [Flights to Colombia](https://expedia.com/Destinations-In-Colombia.d38.Flight-Destinations) - [Flights to Venezuela](https://expedia.com/Destinations-In-Venezuela.d193.Flight-Destinations) - [Flights to Brazil](https://expedia.com/Destinations-In-Brazil.d23.Flight-Destinations) - [Flights to Uruguay](https://expedia.com/Destinations-In-Uruguay.d191.Flight-Destinations) - [Flights to Peru](https://expedia.com/Destinations-In-Peru.d144.Flight-Destinations) - [Flights to Ecuador](https://expedia.com/Destinations-In-Ecuador.d51.Flight-Destinations) - [Flights to Galápagos](https://expedia.com/Destinations-In-Galapagos.d1371.Flight-Destinations) - [Flights to Bolivia](https://expedia.com/Destinations-In-Bolivia.d21.Flight-Destinations) - [Flights to Argentina](https://expedia.com/Destinations-In-Argentina.d8.Flight-Destinations) - [Flights to Guyana](https://expedia.com/Destinations-In-Guyana.d74.Flight-Destinations) Cruises - [Cruises to Galápagos](https://expedia.com/Cruises-to-Galapagos.d1371.Travel-Guide-Cruise) Packages - [Colombia Vacation](https://expedia.com/Colombia.d38.Destination-Travel-Guides) - [Galápagos Vacation](https://expedia.com/Galapagos.d1371.Destination-Travel-Guides) - [Brazil Vacation](https://expedia.com/Brazil.d23.Destination-Travel-Guides) - [Argentina Vacation](https://expedia.com/Argentina.d8.Destination-Travel-Guides) - [Chile Vacation](https://expedia.com/Chile.d36.Destination-Travel-Guides) - [Peru Vacation](https://expedia.com/Peru.d144.Destination-Travel-Guides) - [Ecuador Vacation](https://expedia.com/Ecuador.d51.Destination-Travel-Guides) - [Galápagos All Inclusive Vacation Packages](https://expedia.com/lp/theme-vacations/all-inclusive-vacations/1371/Galapagos) General - [Visit Uruguay](https://expedia.com/Uruguay.dx191) - [Visit Peru](https://expedia.com/Peru.dx144) - [Visit Argentina](https://expedia.com/Argentina.dx8) - [Visit Guyana](https://expedia.com/Guyana.dx74) - [Visit Bolivia](https://expedia.com/Bolivia.dx21)