Photo by Southernmost Illinois Tourism Bureau

Southern Illinois Vacation Rentals

Start date: Check-in selected.
To Date
End date: Check-out

  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals

  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings

  • Upfront pricing

    We are not like the others - we include taxes and fees

Check prices for these dates

Tonight
Jan 13 - Jan 14
Tomorrow
Jan 14 - Jan 15
This weekend
Jan 16 - Jan 18
Next weekend
Jan 23 - Jan 25

Our top choices for Southern Illinois vacation rentals

House (3 Bedrooms) | Interior
Pet-friendly Home w/ Fenced Yard: 'cozy in Casey'

Pet-friendly Home w/ Fenced Yard: 'cozy in Casey'

Pet-friendly Home w/ Fenced Yard: 'cozy in Casey'
3.0 star property
Casey
10.0 out of 10, Exceptional, (1 review)
"Property was very clean and quiet, will definitely schedule for next family reunion."
United States
Anthony
$250 nightly
The price is $275
Jan 14 - Jan 15
Total with taxes and fees
Pet-friendly Home w/ Fenced Yard: 'cozy in Casey'
Interior
Shawnee Wine Trail Farm Stay

Shawnee Wine Trail Farm Stay

Shawnee Wine Trail Farm Stay
Makanda
10.0 out of 10, Exceptional, (11 reviews)
"We loved our stay and all the wonderful animals we got to see."
United States
Jasmine B.
$119 nightly
The price is $126
Jan 27 - Jan 28
Total with taxes and fees
Shawnee Wine Trail Farm Stay
Smart TV, books
Secluded Lake of Egypt Cabin+Kayaks & Fire Pit

Secluded Lake of Egypt Cabin+Kayaks & Fire Pit

Secluded Lake of Egypt Cabin+Kayaks & Fire Pit
Goreville
10.0 out of 10, Exceptional, (35 reviews)
"The property was fabulous and the owners were nothing short of amazing. Definitely would visit again! "
United States
Anonymous traveler
$154 nightly
The price is $163
Jan 19 - Jan 20
Total with taxes and fees
Secluded Lake of Egypt Cabin+Kayaks & Fire Pit
Private kitchen
Cozy cabin, hot tub, high speed internet in the heart of the Shawnee

Cozy cabin, hot tub, high speed internet in the heart of the Shawnee

Cozy cabin, hot tub, high speed internet in the heart of the Shawnee
Simpson
10.0 out of 10, Exceptional, (14 reviews)
"Beautiful, peaceful, clean and cozy cabin in the country"
United States
Tara M.
$180 nightly
The price is $191
Jan 14 - Jan 15
Total with taxes and fees
Cozy cabin, hot tub, high speed internet in the heart of the Shawnee
Exterior
Handicap Accessible Studio w/ Full Kitchen on the River

Handicap Accessible Studio w/ Full Kitchen on the River

Handicap Accessible Studio w/ Full Kitchen on the River
2.0 star property
Stone Church Precinct
8.8 out of 10, Excellent, (6 reviews)
"Lovely property, and cabin was comfortable and clean. The hosts were so accommodating and nice"
United States
Finlay S.
$102 nightly
The price is $109
Jan 14 - Jan 15
Total with taxes and fees
Handicap Accessible Studio w/ Full Kitchen on the River
Terrace/patio
Relaxing Cabin Near Hiking, Fishing & Lake of Egypt

Relaxing Cabin Near Hiking, Fishing & Lake of Egypt

Relaxing Cabin Near Hiking, Fishing & Lake of Egypt
Goreville
10.0 out of 10, Exceptional, (8 reviews)
"The cabin was very clean, organized and cozy! Will definitely stay here again!"
United States
Tchalla J.
$184 nightly
The price is $195
Jan 14 - Jan 15
Total with taxes and fees
Relaxing Cabin Near Hiking, Fishing & Lake of Egypt
Interior
Upscale Cabin w/ Beach Near Lake of Egypt

Upscale Cabin w/ Beach Near Lake of Egypt

Upscale Cabin w/ Beach Near Lake of Egypt
Marion
9.8 out of 10, Exceptional, (70 reviews)
"We really enjoy this location."
Canada
David B.
$139 nightly
The price is $153
Jan 14 - Jan 15
Total with taxes and fees
Upscale Cabin w/ Beach Near Lake of Egypt
1 bedroom, iron/ironing board, free WiFi, bed sheets
Unique loft in historic downtown

Unique loft in historic downtown

Unique loft in historic downtown
Vandalia
10.0 out of 10, Exceptional, (23 reviews)
"Clean, quaint, and conveniently located. Perfect for a weekend retreat!"
United States
Curtis T.
$127 nightly
The price is $135
Jan 18 - Jan 19
Total with taxes and fees
Unique loft in historic downtown
Living area
Justice- Book 1, 2 or 3 Cabins. Pet Friendly for a fee. Lake View

Justice- Book 1, 2 or 3 Cabins. Pet Friendly for a fee. Lake View

Justice- Book 1, 2 or 3 Cabins. Pet Friendly for a fee. Lake View
Goreville
9.8 out of 10, Exceptional, (9 reviews)
"The place and host are awesome!!"
United States
Nicolas S.
$165 nightly
The price is $175
Jan 14 - Jan 15
Total with taxes and fees
Justice- Book 1, 2 or 3 Cabins. Pet Friendly for a fee. Lake View
Property grounds
Lake & Oaks Hideaway- Hidden Cabin on Private Lake

Lake & Oaks Hideaway- Hidden Cabin on Private Lake

Lake & Oaks Hideaway- Hidden Cabin on Private Lake
Waltonville
10.0 out of 10, Exceptional, (55 reviews)
"Great location and good host "
United States
Jared T.
$221 nightly
The price is $234
Jan 15 - Jan 16
Total with taxes and fees
Lake & Oaks Hideaway- Hidden Cabin on Private Lake
Interior
Vintage Charmer on Main Street

Vintage Charmer on Main Street

Vintage Charmer on Main Street
Greenup
10.0 out of 10, Exceptional, (61 reviews)
"Looking forward to staying again on our return trip home"
United States
Karen B.
$131 nightly
The price is $138
Jan 14 - Jan 15
Total with taxes and fees
Vintage Charmer on Main Street
Exterior detail
3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!

3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!

3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!
Makanda
9.8 out of 10, Exceptional, (60 reviews)
"The property was extremely clean and well cared for.would definitely stay again. "
United States
Dan H.
$164 nightly
The price is $181
Jan 14 - Jan 15
Total with taxes and fees
3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!
Outdoor spa tub
Treehouse w/ Hot Tub near Shawnee National Forest

Treehouse w/ Hot Tub near Shawnee National Forest

Treehouse w/ Hot Tub near Shawnee National Forest
Marion
10.0 out of 10, Exceptional, (20 reviews)
"Great place"
United States
James
$216 nightly
The price is $233
Jan 14 - Jan 15
Total with taxes and fees
Treehouse w/ Hot Tub near Shawnee National Forest
Property grounds
Black Ridge Cabin LLC

Black Ridge Cabin LLC

Black Ridge Cabin LLC
Junction
10.0 out of 10, Exceptional, (15 reviews)
"We had an amazin stay. We love everything about this cabin. The hosts were so nice, and they even offered us the buggy ride. The animals added a huge impact, we love the animals, We love the creek. We love being in nature."
United States
Ma Cristina
$227 nightly
The price is $241
Jan 14 - Jan 15
Total with taxes and fees
Black Ridge Cabin LLC
Exterior
Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Anna
10.0 out of 10, Exceptional, (405 reviews)
"Beautiful cabin with a great view of the water from the back porch! Very peaceful and relaxing stay!"
United States
Sarah F.
$190 nightly
The price is $201
Jan 15 - Jan 16
Total with taxes and fees
Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Exterior
Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!

Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!

Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!
Makanda
9.6 out of 10, Exceptional, (40 reviews)
"Everything was very nice. We enjoyed our stay! The cabin had everything we needed."
United States
Cheri U.
$192 nightly
The price is $212
Jan 14 - Jan 15
Total with taxes and fees
Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!
Exterior
A Little Slice Of Heaven

A Little Slice Of Heaven

A Little Slice Of Heaven
Marion
10.0 out of 10, Exceptional, (70 reviews)
"Cozy, comfortable spot to enjoy while exploring the area."
United States
Ariel T.
$165 nightly
The price is $183
Jan 14 - Jan 15
Total with taxes and fees
A Little Slice Of Heaven
Interior
The Tinley House. Close to hiking, hunting. Bike trail and hospital, shopping

The Tinley House. Close to hiking, hunting. Bike trail and hospital, shopping

The Tinley House. Close to hiking, hunting. Bike trail and hospital, shopping
Harrisburg
9.8 out of 10, Exceptional, (24 reviews)
"Great place to stay"
United States
Neil I.
$160 nightly
The price is $170
Jan 16 - Jan 17
Total with taxes and fees
The Tinley House. Close to hiking, hunting. Bike trail and hospital, shopping
Property grounds
The Brunette Treehouse

The Brunette Treehouse

The Brunette Treehouse
Marion
10.0 out of 10, Exceptional, (7 reviews)
"Lovely place to stay, quiet, peaceful. Kid and pet friendly."
United States
Rhiannon H.
$218 nightly
The price is $235
Jan 14 - Jan 15
Total with taxes and fees
The Brunette Treehouse
Exterior detail
Brickway Retreat

Brickway Retreat

Brickway Retreat
Mattoon
9.8 out of 10, Exceptional, (41 reviews)
"This house was perfect! Very clean, beautifully decorated and very cozy. So many nice extras. Because of bad weather we had to modify our stay and we were very grateful that the hosts were able to accommodate us. We would absolutely stay here again. "
United States
Shari
$170 nightly
The price is $180
Jan 14 - Jan 15
Total with taxes and fees
Brickway Retreat
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Southern Illinois Hotel Reviews

Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

10/10 Excellent
"I didn’t try the breakfast so I can’t rate that. Room was spacious, clean, and comfortable. Lots of parking available. Easy access to highway, shopping, and dining."
Julie 2-night trip
Posted 1 day ago
Drury Inn & Suites St. Louis Fairview Heights

Find out more about Southern Illinois

Everything you need to know about Southern Illinois vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Southern Illinois vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Southern Illinois vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Southern Illinois vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Southern Illinois. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Southern Illinois in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $125 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Southern Illinois rentals

At Expedia, we put the best Southern Illinois vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Southern Illinois rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Southern Illinois vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Southern Illinois. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia