A waterfront with Spanish moss-covered trees, a wooden dock, and a distant shoreline.

Melrose Vacation Rentals

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Check prices for these dates

In two weeks
Sep 25 - Sep 27
In two months
Nov 6 - Nov 8
In three months
Dec 4 - Dec 6
In four months
Jan 1 - Jan 3

Our top choices for Melrose vacation rentals

A campfire in a grassy area with chairs and a tree.

1. Shaanti Living • Cozy Private Camper 2

Shaanti Living • Cozy Private Camper 2
Melrose
10.0 out of 10, Exceptional, (3 reviews)
"Very nice camper and great price!"
United States
Katy F.
$89 nightly
The price is $97
Sep 18 - Sep 19
Total with taxes and fees
Shaanti Living • Cozy Private Camper 2
A campfire in a grassy area with chairs and a tree nearby.

2. Shaanti Living • Cozy Studio Blue

Shaanti Living • Cozy Studio Blue
Melrose
10.0 out of 10, Exceptional, (4 reviews)
"Best place ever"
United States
Kevin
$92 nightly
The price is $100
Oct 12 - Oct 13
Total with taxes and fees
Shaanti Living • Cozy Studio Blue
A lakeside cabin with a deck, outdoor seating, and a dock with kayaks.

3. Lakefront A-Frame · Hot Tub + Fire Pit · Dock · Private Lake

Lakefront A-Frame · Hot Tub + Fire Pit · Dock · Private Lake
Melrose
10.0 out of 10, Exceptional, (3 reviews)
"Amazing home! Great stay for my wife and I on our 2 year anniversary! We loved the hot tub and the pedal boat! Seems like a great spot to bring friends next time!"
United States
Keith P.
$251 nightly
The price is $275
Sep 15 - Sep 16
Total with taxes and fees
Lakefront A-Frame · Hot Tub + Fire Pit · Dock · Private Lake
A spacious kitchen with white cabinets, a dining table with chairs, and a ceiling fan.

4. Tranquil Lakehouse with Private Access

Tranquil Lakehouse with Private Access
Melrose
$413 nightly
The price is $460
Sep 24 - Sep 25
Total with taxes and fees
Tranquil Lakehouse with Private Access
A large, white tent with a dining area inside, surrounded by a grassy field and trees.

5. Highland Cow Glamping in a Cozy King Bed Wagon

Highland Cow Glamping in a Cozy King Bed Wagon
Melrose
10.0 out of 10, Exceptional, (2 reviews)
"The wagon was an amazing stay and the animals were an amazing bonus. We will definitely be coming back."
United States
Daniel L.
$260 nightly
The price is $282
Sep 13 - Sep 14
Total with taxes and fees
Highland Cow Glamping in a Cozy King Bed Wagon
A kitchen with wooden cabinets, a refrigerator, a microwave, a sink, and a dining area with a table and chairs.

6. Highland Cow Sanctuary Farmhouse Stay

Highland Cow Sanctuary Farmhouse Stay
Melrose
10.0 out of 10, Exceptional, (2 reviews)
"Real experience, very close to the animals (who are all so nice), amazing host! All excellent"
United States
Pedro A.
$292 nightly
The price is $320
Sep 29 - Sep 30
Total with taxes and fees
Highland Cow Sanctuary Farmhouse Stay
A rustic barn-style structure with a covered porch and a small staircase leading to the entrance.

7. Peaceful Animal Sanctuary Farm Stay on Rescue Farm Near Gainesville & Jacksonville in Melrose, Florida

Peaceful Animal Sanctuary Farm Stay on Rescue Farm Near Gainesville & Jacksonville in Melrose, Florida
Melrose
$333 nightly
The price is $365
Sep 29 - Sep 30
Total with taxes and fees
Peaceful Animal Sanctuary Farm Stay on Rescue Farm Near Gainesville & Jacksonville in Melrose, Florida
A cozy room with a checkered bedspread, wooden walls, and a door leading to another room.

8. Luxury Covered Wagon, Rooterville Animal Sanctuary

Luxury Covered Wagon, Rooterville Animal Sanctuary
Melrose
10.0 out of 10, Exceptional, (6 reviews)
"We enjoyed our two night stay in the wagon. The bedding was comfortable as was the air conditioning! It was fun seeing the animals roaming the farm in the morning and evenings. Our experience during the cow cuddle session was memorable and very informative. Great place to get away for a few days and relax."
United States
Amber S.
$260 nightly
The price is $282
Sep 13 - Sep 14
Total with taxes and fees
Luxury Covered Wagon, Rooterville Animal Sanctuary

9. Luxury Highland Cow Glamping in Cozy Covered Wagon with Peaceful Farm Retreat in Melrose, Florida

Luxury Highland Cow Glamping in Cozy Covered Wagon with Peaceful Farm Retreat in Melrose, Florida
Melrose
$266 nightly
The price is $291
Sep 13 - Sep 14
Total with taxes and fees
Luxury Highland Cow Glamping in Cozy Covered Wagon with Peaceful Farm Retreat in Melrose, Florida

10. Soulful Glamping Experience with Highland Cows, Private Wagon & Nature in Melrose, Florida

Soulful Glamping Experience with Highland Cows, Private Wagon & Nature in Melrose, Florida
Melrose
$266 nightly
The price is $291
Sep 13 - Sep 14
Total with taxes and fees
Soulful Glamping Experience with Highland Cows, Private Wagon & Nature in Melrose, Florida
A small, single-story RV-style accommodation with a covered porch and a visible kitchen area, surrounded by trees.

11. "La Grande" Retro Escape

"La Grande" Retro Escape
Gainesville
10.0 out of 10, Exceptional, (7 reviews)
"The host was very accommodating. Sweet place. "
United States
Deanne H.
$139 nightly
The price is $154
Sep 14 - Sep 15
Total with taxes and fees
"La Grande" Retro Escape
A covered deck with wooden flooring, a wooden bench, wicker chairs, and a table.

12. Fish from own dock or in Palatka, Visit Ocala National Forest, FU Gators 30+ min

Fish from own dock or in Palatka, Visit Ocala National Forest, FU Gators 30+ min
Hawthorne
10.0 out of 10, Exceptional, (21 reviews)
"The house was awesome. Every time we go there it’s like a second home. My husband and son caught and released a bunch of bass. We love coming here. "
United States
Shannon D.
$253 nightly
The price is $278
Sep 13 - Sep 14
Total with taxes and fees
Fish from own dock or in Palatka, Visit Ocala National Forest, FU Gators 30+ min
A kitchen with a sink, a microwave, and cabinets.

13. The Humming Bird Suite - Affordable Lakefront Fun

The Humming Bird Suite - Affordable Lakefront Fun
3.0 star property
Keystone Heights
$109 nightly
The price is $123
Sep 14 - Sep 15
Total with taxes and fees
The Humming Bird Suite - Affordable Lakefront Fun
A dining area with a table set for four, a vase with dried flowers, and a view of a dock and greenery outside.

14. Relaxing Lakefront Escape with Hot Tub, Fire Pit, Kayaks & Paddle Boards

Relaxing Lakefront Escape with Hot Tub, Fire Pit, Kayaks & Paddle Boards
Interlachen
10.0 out of 10, Exceptional, (6 reviews)
"What a beautiful vacation we had here, and the host could not have been more attentive or generally all round kind and considerate. I miss being there!"
United States
Lynn W.
$401 nightly
The price is $440
Sep 14 - Sep 15
Total with taxes and fees
Relaxing Lakefront Escape with Hot Tub, Fire Pit, Kayaks & Paddle Boards
A wooden dock with a chair, surrounded by trees and a calm water body.

15. Yearling Restaurant and Cabins

Yearling Restaurant and Cabins
2.5 star property
Hawthorne
9.2 out of 10, Wonderful, (217 reviews)
"Beautiful venue."
United States
Riley
$139 nightly
The price is $156
Sep 13 - Sep 14
Total with taxes and fees
Yearling Restaurant and Cabins
A bedroom with a large bed, a wooden door, a window with blinds, and a kitchen area visible through an open door.

16. Fisherman’s Paradise

Fisherman’s Paradise
Interlachen
10.0 out of 10, Exceptional, (4 reviews)
"The stay was awesome. Very clean and convenient to the lake and town. Will stay again"
United States
Anthony S.
$305 nightly
The price is $335
Sep 13 - Sep 14
Total with taxes and fees
Fisherman’s Paradise
A bedroom with a large bed, a ceiling fan, a desk with a chair, and a window with curtains.

17. Private suite with own entry in vibrant Gainesville

Private suite with own entry in vibrant Gainesville
Gainesville
9.8 out of 10, Exceptional, (24 reviews)
"We loved our weekend stay. The room is so adorable and comfortable. The host immediately replies to your messages and is so kind. The rental is just a few minutes from the stadium making it great for Gator games. We would love to return in the future."
United States
Ashley
$130 nightly
The price is $144
Sep 13 - Sep 14
Total with taxes and fees
Private suite with own entry in vibrant Gainesville
A porch with two chairs and a birdhouse.

18. Palmetto Cottage-1930’s Florida Cottage

Palmetto Cottage-1930’s Florida Cottage
Micanopy
9.8 out of 10, Exceptional, (60 reviews)
"Perfect for a quick over night after a concert in Gainesville. "
United States
Courtney B.
$211 nightly
The price is $232
Sep 13 - Sep 14
Total with taxes and fees
Palmetto Cottage-1930’s Florida Cottage
A spacious living room with a fireplace, a dining area, and a kitchen in the background.

19. Raceway Retreat, just 12 miles from UF/downtown, relaxing country getaway!

Raceway Retreat, just 12 miles from UF/downtown, relaxing country getaway!
Gainesville
10.0 out of 10, Exceptional, (13 reviews)
"Wonderful host and very comfortable"
United States
Tertia
$293 nightly
The price is $325
Sep 15 - Sep 16
Total with taxes and fees
Raceway Retreat, just 12 miles from UF/downtown, relaxing country getaway!
A two-story house with a porch, surrounded by trees and plants.

20. Juniper Cottage — In the Heart of Old Florida

Juniper Cottage — In the Heart of Old Florida
Micanopy
9.4 out of 10, Exceptional, (17 reviews)
"A charming cottage and town!"
United States
MARY
$208 nightly
The price is $229
Sep 13 - Sep 14
Total with taxes and fees
Juniper Cottage — In the Heart of Old Florida
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Melrose Hotel Reviews

Hampton Inn Gainesville

Hampton Inn Gainesville

10/10 Excellent
"Will definitely stay again. Clean property and friendly staff!"
Robert 1-night trip
Posted 2 hours ago
Hampton Inn Gainesville

Find out more about Melrose

Everything you need to know about Melrose vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Melrose vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Melrose vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Melrose vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Melrose. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Melrose in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $144 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Melrose rentals

At Expedia, we put the best Melrose vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Melrose rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Melrose vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Melrose. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find vacation rentals in Melrose?

Yes, you can find vacation rentals close to popular attractions in Melrose, or you can select a more secluded option if you're looking for a relaxing stay.

What are some of the best vacation home rentals that Melrose has to offer?

3 Bedroom House on Private Scenic Lake Mable: This Melrose vacation home rental is located on a lake and has a garden, a selection of games, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family.

How many vacation rentals are there in Melrose?

Choose from 25 Expedia vacation rentals in Melrose for a memorable vacation.

What’s there to see and do in Melrose?

Explore the area and family-friendly sights such as Waldo Motorsports, or get out into nature at a spot like Santa Fe Lake. In the larger area, you’ll find Gainesville Raceway and Ironwood Golf Course.

What’s a vacation rental in Melrose like?

Vacation rentals are private properties you can stay in for short or long periods in Melrose. Vacation rentals provide amenities like kitchens and laundry facilities so you'll have a home away from home. If you're concerned about a sanitized environment, a vacation rental can offer a sense of safety away from public hotel elevators and busy reception areas while still allowing you the experience of travel. You'll also have more space in a vacation rental than in a hotel, which is another reason why a vacation rental is an attractive option for a small group gathering.