A waterfront with Spanish moss-covered trees, a wooden dock, and a distant shoreline.

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Our top choices for Melrose hotels

A spacious lobby with a sectional sofa, a wooden cabinet, and a television mounted on the wall.
A hotel lobby with a stone wall, a flat-screen TV, orange upholstered seating, and a lamp.
A hotel room with two beds, a large headboard, bedside lamps, and a view of the outdoors through sheer curtains.
A hotel room with a large window offering a view of a cityscape, a blue armchair, and a small table with a lamp.

1. Drury Inn & Suites Gainesville

Drury Inn & Suites Gainesville
Gainesville
Guest highlights
  • Spacious pool and hot tub area
  • Free breakfast buffet with variety
$105 nightly
$118 total
Oct 1 - Oct 2
Total with taxes and fees
Drury Inn & Suites Gainesville
A multi-story hotel with a central entrance, palm trees, and a clear sky.
A hotel room with a bed, a desk, a television, a sofa, and artwork on the wall.
A modern living room with a green sofa, a round coffee table, and a fireplace.
A spacious hotel lobby with a modern staircase, a seating area with a sofa and chairs, and a dining area in the background.

2. Country Inn & Suites by Radisson, Gainesville, FL

Country Inn & Suites by Radisson, Gainesville, FL
Gainesville
Guest highlights
  • Great breakfast options available
  • Ample parking on the property
  • Outstanding staff on hand each day
$88 nightly
$99 total
Oct 4 - Oct 5
Total with taxes and fees
Country Inn & Suites by Radisson, Gainesville, FL
A person pouring a drink into a glass.
A landscaped courtyard with palm trees, a well-maintained lawn, and a building with multiple windows and balconies.
A conference room with rows of green chairs, a large screen, and two chandeliers.
A hotel room with a sofa, a desk, a chair, a bed, a TV, and a dining table with a glass and cookie.

3. Hotel Indigo Gainesville-Celebration Pointe by IHG

Hotel Indigo Gainesville-Celebration Pointe by IHG
Gainesville
Guest highlights
  • Convenient parking on the property
  • Delicious dining options at the restaurant
  • Delicious breakfast with excellent service
$107 nightly
$120 total
Sep 30 - Oct 1
Total with taxes and fees
Hotel Indigo Gainesville-Celebration Pointe by IHG
A hotel room with a bed, two bedside tables with lamps, a large bathtub, and green walls.
A Sleep Inn & Suites building with a clear entrance, a covered waiting area, and a parking lot.
Outdoor lounge chairs with metal frames and fabric seats, arranged in rows.
A breakfast bar with a juice dispenser, cereal boxes, and fruit bowls.

4. Sleep Inn & Suites University/Shands

Sleep Inn & Suites University/Shands
Gainesville
Guest highlights
  • Full breakfast with hot options
  • Clean and warm pool
  • Easy and secure parking available
$81 nightly
$91 total
Oct 18 - Oct 19
Total with taxes and fees
Sleep Inn & Suites University/Shands
A modern interior with a staircase, a seating area, and a colorful abstract wall design.
A modern bar area with a marble countertop, bar stools, and pendant lighting.
A modern hotel lobby with a round table featuring two drinks, a sofa, and a colorful wall art piece.
A spacious lobby with modern furniture, large windows, and a colorful abstract wall.

5. Hyatt Place Gainesville Downtown

Hyatt Place Gainesville Downtown
Downtown Gainesville
Guest highlights
  • Clean and fantastic pool area
  • On-site restaurant with good food
  • Delicious breakfast buffet options
$98 nightly
$110 total
Oct 4 - Oct 5
Total with taxes and fees
Hyatt Place Gainesville Downtown
A modern building with a curved facade, a landscaped pathway, and a body of water in the foreground.
An outdoor seating area with tables and chairs, a water feature, and modern buildings in the background.
A modern living room with a flat-screen TV, wooden shelving, a small table, a sofa, and a large window offering a city view.
A modern hotel room with two beds, a flat-screen TV, wooden wardrobe, and large windows offering a view of a cityscape and water feature.

6. Hotel Eleo at the University of Florida

Hotel Eleo at the University of Florida
Gainesville
Guest highlights
  • Excellent food in the on-site restaurant
  • Easy valet parking service available
  • Spacious and clean hotel rooms
$170 nightly
$191 total
Oct 1 - Oct 2
Total with taxes and fees
Hotel Eleo at the University of Florida
A modern living room with a fireplace, comfortable seating, a flat-screen TV, and a large window.
A hotel room with a bed, a desk, a chair, a sofa, and a window.
A fire pit area surrounded by stone tiles, with a metal fence in the background.
A modern hotel lobby with a long dining table, multiple seating areas, and a large window with curtains.

7. Comfort Suites Gainesville near University

Comfort Suites Gainesville near University
Gainesville
Guest highlights
  • Great variety at breakfast
  • Excellent on-site parking
  • Fresh coffee and tea for guests
$84 nightly
$95 total
Oct 18 - Oct 19
Total with taxes and fees
Comfort Suites Gainesville near University
A modern dining area with tables and chairs, a kitchen counter, and a sign reading "höm cooking".
A hotel room with two beds, a ceiling fan, a TV, and a desk with a chair.
A hotel with a modern facade, a covered entrance, and a palm tree in front.

8. HOM Hotel Gainesville, SureStay Collection by Best Western

HOM Hotel Gainesville, SureStay Collection by Best Western
Gainesville
Guest highlights
  • Clean and inviting pool area
  • Complimentary breakfast with fresh choices
  • Easy parking on the property
$72 nightly
$82 total
Oct 4 - Oct 5
Total with taxes and fees
HOM Hotel Gainesville, SureStay Collection by Best Western
A spacious hotel lobby with a curved sofa, a patterned carpet, and a large window with sheer curtains.
A large banquet hall with round tables, chairs, and floral centerpieces.
A hotel lobby with a blue patterned carpet, black round tables with candles, beige sofas, and a curved seating area.
A bar area with multiple seating arrangements and a bar counter.

9. Hilton University of Florida Conference Center Gainesville

Hilton University of Florida Conference Center Gainesville
Gainesville
Guest highlights
  • Spacious rooms with space to unwind
  • On-site restaurant with great options
  • Consistent and thorough housekeeping service
$106 nightly
$119 total
Oct 4 - Oct 5
Total with taxes and fees
Hilton University of Florida Conference Center Gainesville
A large, multi-story hotel with a central courtyard, palm trees, and an American flag.
A bar area with wooden chairs, a bar counter, and a television mounted on the wall.
A spacious dining area with multiple tables and chairs, a kitchen area with a coffee station, and large windows allowing natural light.
A living room with a brown leather sofa, a glass-top coffee table, and a framed picture on the wall.

10. Best Western Gateway Grand

Best Western Gateway Grand
Gainesville
Guest highlights
  • Breakfast buffet with a great selection
  • Clean pool and hot tub
  • Friendly and responsive staff members
$93 nightly
$104 total
Sep 27 - Sep 28
Total with taxes and fees
Best Western Gateway Grand
A modern hotel with a prominent 'La Quinta' sign, a covered entrance, and a well-maintained outdoor area with a parking lot.
A modern lounge area with a flat-screen TV, a fireplace, teal and brown seating, patterned carpet, and a wall-mounted clock.
A hotel reception area with directional signs for elevators, floor 1, pool restrooms, and business center.
A hotel lobby with a seating area featuring sofas and armchairs, a central coffee table, and a flat-screen TV mounted on the wall.

11. La Quinta by Wyndham Gainesville

La Quinta by Wyndham Gainesville
Gainesville
Guest highlights
  • Great breakfast buffet options
  • Convenient parking on the property
$91 nightly
$102 total
Sep 27 - Sep 28
Total with taxes and fees
La Quinta by Wyndham Gainesville
A spacious living area with a curved ceiling, a large flat-screen TV, and a modern sofa.
A modern interior with a seating area, large windows, and a stone wall with a menu.
A modern kitchen with a curved island, pendant lighting, and a map of Gainesville on the wall.
A modern lounge area with seating arrangements, a flat-screen TV, and artwork on the walls.

12. Holiday Inn Gainesville - University Center by IHG

Holiday Inn Gainesville - University Center by IHG
University Heights
Guest highlights
  • Short walk to multiple local restaurants
  • Varied breakfast to start the day
  • Friendly and helpful staff service
$101 nightly
$114 total
Oct 4 - Oct 5
Total with taxes and fees
Holiday Inn Gainesville - University Center by IHG
A modern building entrance with a covered entrance area, glass doors, and surrounding greenery.
A hotel room with a grey sofa, a small table, a lamp, a framed picture on the wall, and a bed with a blue blanket.
A hotel room with two beds, a desk, a TV, and a window with curtains.
A hotel lobby with a reception desk, seating area, and a view of the dining area.

13. Comfort Inn Gainesville - University Area

Comfort Inn Gainesville - University Area
Gainesville
Guest highlights
  • Nice, clean pool area
  • Excellent and helpful staff on hand
  • Delicious breakfast with fresh options
$81 nightly
$92 total
Oct 18 - Oct 19
Total with taxes and fees
Comfort Inn Gainesville - University Area
An outdoor patio area with seating and tables, string lights, and a building with large windows.
A spacious lobby with a herringbone wood floor, a central seating area with a large table, and a staircase leading to an upper level.
A hotel entrance with a wooden ceiling, large windows, and potted plants.
A modern lounge area with sofas, tables, and bar seating.

14. DoubleTree by Hilton Gainesville

DoubleTree by Hilton Gainesville
Gainesville
Guest highlights
  • Good food quality at the on-site restaurant
  • Excellent staff responsiveness at front desk
  • Delicious breakfast each morning
$81 nightly
$91 total
Oct 4 - Oct 5
Total with taxes and fees
DoubleTree by Hilton Gainesville
A Days Inn by Wyndham sign with a sunburst logo, a blue arch, and a clear sky.
A Days Inn by Wyndham hotel with a blue awning, large windows, and a parking lot.
A reception area with a desk, two chairs, framed pictures, and a sign for Days Inn.

15. Days Inn by Wyndham Gainesville Hospital/University Area

Days Inn by Wyndham Gainesville Hospital/University Area
Gainesville
Guest highlights
  • Free on-site parking
  • Comfortable king bed in the room
$59 nightly
$66 total
Sep 27 - Sep 28
Total with taxes and fees
Days Inn by Wyndham Gainesville Hospital/University Area
A multi-story hotel with a flat roof and a central entrance.
A hotel room with two beds, a desk, a chair, a television, and a lamp.
A lobby with a reception desk, a stone wall with a sign, a coffee table, two armchairs, and a potted plant.
A compact living space with a sofa, a coffee table, a kitchenette, and a painting on the wall.

16. Red Roof Inn PLUS+ Gainesville

Red Roof Inn PLUS+ Gainesville
Gainesville
Guest highlights
  • Attentive staff on hand each day
  • Comfortable rooms with space to unwind
$58 nightly
$66 total
Sep 30 - Oct 1
Total with taxes and fees
Red Roof Inn PLUS+ Gainesville
A large, two-story house with a porch, multiple windows, and a chimney.
A grand staircase with ornate carpet, a cozy sitting area with a sofa and chairs, and a large window with a view.
A garden with a stone fountain, a gazebo, and a winding brick path.
A cozy living room with a Christmas tree, a fireplace with stockings, and a view through a window.

17. Sweetwater Branch Inn

Sweetwater Branch Inn
Gainesville
Guest highlights
  • Delicious hot breakfast options
  • Charming and well-located property
  • Pool and hot tub outdoors
$112 nightly
$126 total
Oct 4 - Oct 5
Total with taxes and fees
Sweetwater Branch Inn
An outdoor patio area with string lights, potted plants, and outdoor furniture.
A restaurant with a counter, seating area, and a TV screen.
A modern bar area with a counter, stools, and a variety of bottles and glasses.
A double bed with white bedding and multiple pillows, a wooden headboard, and a framed picture on the wall.

18. Gainesville Lodge

Gainesville Lodge
Gainesville
Guest highlights
  • Welcoming team from check-in onwards
  • Easy and secure parking available
$92 nightly
$103 total
Sep 27 - Sep 28
Total with taxes and fees
Gainesville Lodge
A Super 8 hotel with a well-maintained garden, palm trees, and a stone sculpture.
A dining area with a high table and multiple chairs, a kitchen area with a counter, and a staircase leading to another level.
A hotel room with two beds, a desk, a chair, a television, and a window with curtains.
A modern kitchen with a built-in island, a flat-screen TV mounted on the wall, and a wooden door labeled "office".

19. Super 8 by Wyndham Gainesville I-75 Hospital University Area

Super 8 by Wyndham Gainesville I-75 Hospital University Area
Gainesville
Guest highlights
  • Free breakfast with waffles and toast
  • Ample on-site parking space
  • Great value for the price offered
$48 nightly
$54 total
Oct 4 - Oct 5
Total with taxes and fees
Super 8 by Wyndham Gainesville I-75 Hospital University Area
A modern bar area with wooden bar stools, pendant lighting, and artwork on the walls.
A hotel room with a kitchenette, a bed, a desk with a chair, and a bathroom.
A hotel hallway with carpeted floors, doors on both sides, and overhead lighting.
A hotel reception desk with a wooden panel design, a digital kiosk, and a "Welcome to the Sun Shine State" sign.

20. Hampton Inn Gainesville

Hampton Inn Gainesville
Gainesville
Guest highlights
  • Near Downtown Gainesville
  • Hot breakfast with great choices
  • Comfortable beds and pillows
$87 nightly
$98 total
Oct 4 - Oct 5
Total with taxes and fees
Hampton Inn Gainesville
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Where to stay in and around Melrose

Explore the Melrose area for a perfect blend of outdoor adventure and charming scenery. Discover the heart of Melrose with its friendly atmosphere, or take a short trip to nearby Palm Springs for a romantic getaway. Enjoy the historic preservation along Duval Street for a unique travel experience.

Earleton

Discover Earleton, a charming destination perfect for families and nature lovers who will appreciate its serene environment and outdoor adventures. Just a short distance from Melrose, this lovely city offers access to beautiful spots like Santa Fe Lake and Gold Head Branch State Park, where visitors can enjoy recreational activities and breathtaking scenery. With a welcoming community and a variety of attractions nearby, Earleton is an excellent choice for travelers seeking memorable experiences in Florida.

Grandin

Experience the charm of Grandin, a delightful destination for families and nature lovers seeking a budget-friendly getaway. Nestled in Melrose, Grandin offers easy access to scenic spots like Flamingo Lake and Gold Head Branch State Park, perfect for outdoor adventures. Visitors can also enjoy the local Interlachen Branch Library for a relaxing afternoon. With its tranquil atmosphere and beautiful surroundings, Grandin is a smart choice for your next vacation stay.

A vast forested landscape with multiple lakes and a clear sky.
An aerial view of a large lake surrounded by dense forests and a few buildings along the shoreline.
A lake surrounded by dense forest and residential areas.
A forested area with a wooden bridge and a stream.
Photo by Gavin Conroy

Keystone Heights

Outdoor enthusiasts will love Keystone Heights, known for its stunning natural scenery and family-friendly atmosphere. This charming city offers easy access to beautiful spots like Santa Fe Lake and Gold Head Branch State Park, perfect for a day of adventure and relaxation. With its nearby recreational areas and unique attractions, including the Camp Blanding Museum and Memorial Park, Keystone Heights provides a delightful escape. Located about 5 miles from Melrose, it’s an excellent choice for your vacation stay.

Lake Geneva

Ideally situated for families and nature lovers, Lake Geneva offers a perfect weekend getaway filled with scenic beauty and outdoor activities. Visitors can enjoy the tranquility of Santa Fe Lake, explore the lush trails at Gold Head Branch State Park, or unwind at Dowda Park. With its proximity to Melrose, about 5 miles away, Lake Geneva is an excellent choice for those looking to immerse themselves in nature while experiencing the charm of a quaint village. It's a smart hotel booking choice for your next vacation.

Orange Heights

Travelers seeking a blend of family-friendly activities and natural beauty will find Orange Heights to be the ideal base for their vacation. This charming village offers easy access to outdoor adventures, with nearby attractions like the scenic Santa Fe Lake and the historic University of Florida. Visitors can enjoy exciting events at the Ben Hill Griffin Stadium, making it a vibrant spot for both relaxation and entertainment. With its close proximity of about 5 miles from Melrose, Orange Heights is a smart choice for your getaway.

Stay near popular attractions around Melrose

Escape to Melrose, Florida, where outdoor adventures and stunning scenery await. With charming lakes, serene parks, and romantic spots, this hidden gem is perfect for couples and nature lovers alike. Discover the beauty of the great outdoors and create unforgettable memories in this picturesque destination.
A waterfront with Spanish moss-covered trees, a wooden dock, and a distant shoreline.
Photo by Matt Mateo

Santa Fe Lake

A go-to area recognized for its romantic scenery, Santa Fe Lake offers outdoor enthusiasts a perfect spot to unwind. With its beautiful beach vibes, it's an ideal destination for relaxation and adventure. Located about 3 miles from Melrose, staying near the lake provides easy access to this picturesque retreat.
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A forested area with a wooden bridge and a stream.
Photo by Gavin Conroy

Mike Roess Gold Head Branch State Park

10.0/10 (1 review)
Often cited as a favorite for outdoor enthusiasts, Gold Head Branch State Park offers stunning scenery and adventurous trails in Keystone Heights, Florida. Located about 11 miles from Melrose, it’s a perfect spot for a day of exploration and relaxation, making it convenient for those staying nearby.
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A forested area with a wooden bridge and a stream.
Photo by Gavin Conroy

Mike Roess Gold Head Branch State Park

10.0/10 (1 review)
Perfectly suited for outdoor enthusiasts, Mike Roess Gold Head Branch State Park offers a blend of adventure and stunning scenery. Located about 11 miles from Melrose, this park invites visitors to explore its lush landscapes and unique features, making it a convenient spot for a nature-filled getaway.
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Lake Como United Methodist Church

Highly recommended for travelers interested in local culture, Lake Como United Methodist Church offers a welcoming atmosphere and community spirit. Located about 15 miles from Melrose, this church invites visitors to experience its unique cultural vibes, making it a convenient stop during your exploration of the area.
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Clear Lake

No trip is complete without a visit to Clear Lake, a picturesque destination perfect for outdoor lovers seeking romance and scenic beauty. Located about 8 miles from Melrose, this serene lake offers a tranquil escape with its beach vibes. Staying near Clear Lake ensures easy access to its stunning views and relaxing atmosphere.
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Lake Lucy

Discover the appeal of this scenic spot, ideal for couples and families seeking outdoor relaxation. Lake Lucy offers stunning views and a tranquil atmosphere, perfect for enjoying nature. Located about 8 miles from Melrose, it's a convenient getaway for those looking to unwind by the water.
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Lake Galilee

For nature lovers seeking a serene escape, Lake Galilee offers stunning scenery and a romantic atmosphere. Enjoy the tranquil beach vibes while exploring the surrounding outdoors. Located about 12 miles by car from Melrose, it's an easy drive for a refreshing getaway, making it a convenient spot to unwind.
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Flamingo Lake

A must-see for outdoor lovers, Flamingo Lake offers beautiful scenery and a romantic atmosphere perfect for a relaxing getaway. Located about 10 miles from Melrose, this spot boasts inviting beach vibes, making it a serene choice for your vacation. Staying nearby ensures easy access to this picturesque destination.
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Learn more about Melrose

Nestled along Lake Santa Fe, this charming town offers peaceful kayaking and fishing at Melrose Bay Park. Art lovers can browse local galleries and studios, then enjoy fresh farm-to-table dining at the weekend farmers' market.

See all hotels in Melrose
A waterfront with Spanish moss-covered trees, a wooden dock, and a distant shoreline.
Photo by Matt Mateo

Top Melrose Hotel Reviews

Red Roof Inn PLUS+ Gainesville

Red Roof Inn PLUS+ Gainesville

10/10 Excellent
"Clean and safe good bedding good staff."
Jeff 1-night trip
Posted 2 hours ago
Red Roof Inn PLUS+ Gainesville
Hyatt Place Gainesville Downtown

Hyatt Place Gainesville Downtown

10/10 Excellent
"Very convenient to shops and eateries."
Claire 1-night trip
Posted 5 hours ago
Hyatt Place Gainesville Downtown
Hotel Indigo Gainesville-Celebration Pointe by IHG

Hotel Indigo Gainesville-Celebration Pointe by IHG

8/10 Good
"I was disappointed that Hotel Indigo did not offer a free breakfast. We stayed at a number of hotels during our trip and all of them had a free breakfast included in the price except for this one. The hotel was clean, bathrooms updated, and the staff were friendly. They also didn’t supply enough towels in the bathroom and there was no alarm clock."
Debbie 1-night trip
Posted 18 hours ago
Hotel Indigo Gainesville-Celebration Pointe by IHG
Comfort Suites Gainesville near University

Comfort Suites Gainesville near University

8/10 Good
"Good breakfast but the trash bins by the elevators weren't cleaned out regularly and therefore smelled a bit funky."
Amanda 2-night trip
Posted 20 hours ago
Comfort Suites Gainesville near University
Country Inn & Suites by Radisson, Gainesville, FL

Country Inn & Suites by Radisson, Gainesville, FL

8/10 Good
"Large clean room, good breakfast, quiet location. Would happily stay again."
John 1-night trip
Posted 23 hours ago
Country Inn & Suites by Radisson, Gainesville, FL
Gainesville Lodge

Gainesville Lodge

8/10 Good
"Staff was extremely friendly and attentive."
Chris 1-night trip
Posted 2 days ago
Gainesville Lodge
Hampton Inn Gainesville

Hampton Inn Gainesville

10/10 Excellent
"It was a great experience."
Krisztina 1-night trip
Posted 3 days ago
Hampton Inn Gainesville
Hilton University of Florida Conference Center Gainesville

Hilton University of Florida Conference Center Gainesville

10/10 Excellent
"Great!"
Trenton 2-night trip
Posted 5 days ago
Hilton University of Florida Conference Center Gainesville
3 Bedroom House on Private Scenic Lake Mable

3 Bedroom House on Private Scenic Lake Mable

10/10 Excellent
"Very cozy, peaceful, laid back. It was just what we needed that weekend since we where dropping our son of at UF."
Heriberto 2-night trip
Posted 1 month ago
3 Bedroom House on Private Scenic Lake Mable

More cheap stays in Melrose

Red Roof Inn PLUS+ Gainesville

Red Roof Inn PLUS+ Gainesville

3500 Southwest 42nd St Gainesville FL
$58 nightly
$66 total
Sep 30 - Oct 1
Total with taxes and fees
7.4/10 Good! (1,327 reviews)
Red Roof Inn PLUS+ Gainesville
HOM Hotel Gainesville, SureStay Collection by Best Western

HOM Hotel Gainesville, SureStay Collection by Best Western

3905 Sw 43Rd St Gainesville FL
$72 nightly
$82 total
Oct 4 - Oct 5
Total with taxes and fees
HOM Hotel Gainesville, SureStay Collection by Best Western
Sleep Inn & Suites University/Shands

Sleep Inn & Suites University/Shands

4110 SW 40th Boulevard Gainesville FL
$81 nightly
$91 total
Oct 18 - Oct 19
Total with taxes and fees
Sleep Inn & Suites University/Shands
Comfort Inn Gainesville - University Area

Comfort Inn Gainesville - University Area

3440 SW 40th Blvd Gainesville FL
$81 nightly
$92 total
Oct 18 - Oct 19
Total with taxes and fees
Comfort Inn Gainesville - University Area
Comfort Suites Gainesville near University

Comfort Suites Gainesville near University

2603 SW 13TH STREET Gainesville FL
$84 nightly
$95 total
Oct 18 - Oct 19
Total with taxes and fees
9.2/10 Wonderful! (1,504 reviews)
Comfort Suites Gainesville near University
Quality Inn & Suites Palatka Riverfront

Quality Inn & Suites Palatka Riverfront

201 N 1st Street Palatka FL
$88 nightly
$98 total
Oct 18 - Oct 19
Total with taxes and fees
8.4/10 Very Good! (1,032 reviews)
Quality Inn & Suites Palatka Riverfront

Hotels in Melrose with star-rating

Find out more about Melrose

Top reasons to visit Melrose

  • Outdoor Adventures: Melrose is ideal for exploring beautiful lakes, national and state parks, and urban parks, perfect for nature enthusiasts.
  • Charming Atmosphere: The friendly vibe and inviting main streets make Melrose a great destination for romantic getaways or family fun.
  • Unique Experiences: Don't miss whale watching, which offers a memorable touch to your vacation in this quaint town.
  • Variety of Accommodations: Choose from cozy motels to inviting hotels, catering to diverse vacation needs.
  • Accessible Location: Just a short drive from Gainesville and Palatka, Melrose is conveniently located for easy exploration.

Find great hotels near Melrose

Discover a range of hotel accommodations in Melrose, Florida, perfect for your vacation needs. Whether you're seeking a pet-friendly stay, a comfortable spot for business travel, or an adventure-filled experience, Melrose offers a variety of options. From cozy motels to inviting hotels, you'll find the perfect room to make your visit enjoyable and memorable.

  • Hotel Eleo at the University of Florida: A 3.5-star hotel with an impressive guest rating of 9.4, Hotel Eleo at the University of Florida is a charming retreat located 18 miles from Melrose. This property stands out for its pet-friendly atmosphere, making it an excellent choice for travelers who wish to bring their furry companions along. With a variety of pet amenities, including a fee-waived service animal policy, guests can feel at home while enjoying the university's vibrant surroundings. The hotel offers a stylish blend of modern comfort and Southern hospitality, creating an inviting space for both relaxation and exploration.
  • Hyatt Place Gainesville Downtown: A 3-star hotel with a notable guest rating of 9.2, Hyatt Place Gainesville Downtown is situated 17 miles from Melrose and caters to families and business travelers alike. This property features a unique hot spring theme, with nearby access to natural hot springs for a rejuvenating experience. Amenities for children, such as free cribs and pool toys, ensure that families can enjoy their stay without compromising comfort. The hotel's modern design and welcoming atmosphere make it an ideal base for exploring the vibrant downtown area while enjoying quality time with loved ones.
  • Hampton Inn & Suites Gainesville-Downtown: A budget-friendly option with a guest rating of 8.6, Hampton Inn & Suites Gainesville-Downtown is located 17 miles from Melrose. This hotel is perfect for travelers seeking a pet-friendly environment while balancing business and leisure. It has a pet policy that accommodates various sizes, with fees waived for service animals. Guests will appreciate the comfortable rooms, complimentary breakfast, and convenient access to downtown, making it a practical choice for those looking to stay connected while enjoying the local attractions.

Where to stay in and around Melrose

Melrose, Florida, offers a charming escape with its friendly atmosphere and outdoor allure, perfect for romantic getaways or family adventures. Just a short drive from nearby cities like Gainesville and Palatka, you'll find local amenities and inviting main streets to explore. Enjoy scenic views and summer staycations that highlight the beauty of this hidden gem, making it an ideal destination for relaxation and discovery.

  • Earleton: Nestled just 3 miles from Melrose, Earleton is a charming city that offers a delightful outdoor experience, making it a popular choice for those seeking scenic views and romantic getaways. Visitors can explore its beautiful recreational areas, indulge in adventure activities, and even dive into underwater sports. The proximity to stunning lakes, rivers, and a national state park enhances its appeal, providing ample opportunities for nature lovers to immerse themselves in the great outdoors. The best time to visit is during the peak months of March, August, and November, when the weather is ideal for outdoor adventures.
  • Grandin: Located close to Melrose, Grandin is a quaint village known for its picturesque scenery and romantic atmosphere. Travelers flock here for its serene charm, with the local lakes serving as perfect spots for relaxation and reflection. The village provides a peaceful escape from the hustle and bustle, making it an ideal destination for couples and outdoor enthusiasts alike. Similar to Earleton, Grandin experiences peak visitor numbers in March, August, and November, making these months perfect for a visit to enjoy its natural beauty.
  • Keystone Heights: A mere 5 miles from Melrose, Keystone Heights is a unique city characterized by its island-like features. This vibrant locale is a haven for outdoor enthusiasts, offering various recreational areas and adventure activities, including underwater sports. Visitors are drawn to its breathtaking lakes, rivers, and the nearby national state park, which provide stunning backdrops for exploration and relaxation. Keystone Heights sees peak travel seasons in February to March and December, making it an excellent choice for tourists looking to connect with nature and enjoy a romantic getaway.

Things to do near Melrose

Melrose, Florida, is perfect for outdoor adventures and romantic getaways. Visitors can enjoy a range of activities, including exploring the beautiful recreational areas, indulging in educational experiences, and hitting the golf courses. While shopping opportunities abound, don't miss the chance for unique experiences like whale watching, which adds a memorable touch to your vacation in this charming town.

Shopping

In Melrose, enjoy local shops offering unique gifts and souvenirs. If you're up for a drive, visit the Gainesville Mall, about 15 miles away, which features a variety of national retailers and dining options for a more extensive shopping experience.

Recreation

Haile Plantation Golf and Country Club offers a luxurious golfing experience just 25 miles from Melrose, featuring pristine greens and upscale amenities. Similarly, Magnolia Point Golf and Country Club, located 29 miles away, provides an elegant atmosphere perfect for relaxation and recreation amidst beautiful landscapes.

Adventure

Explore the serene waters of Lake Santa Fe for kayaking and fishing, or hike the scenic trails at the nearby San Felasco Hammock Preserve State Park for a chance to spot local wildlife. For a thrilling experience, try horseback riding at local stables for a fun adventure.

Nightlife

Explore the vibrant nightlife in Melrose by visiting The Melrose Community Center for local events and gatherings. For a laid-back evening, check out the Melrose Pub, where you can enjoy a cold drink and mingle with friendly locals in a cozy atmosphere.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Melrose

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Melrose are July and December to January, where the prices are slightly lower. This is in comparison to May and September to October, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Melrose is Tuesday. The most expensive day to stay in Melrose is Saturday.
  • Find cheap hotels on Expedia: Utilize Expedia’s search tool to customize your travel preferences, such as your budget, desired location, and preferred hotel type. For instance, selecting the Eco-certified option will showcase sustainable and environmentally friendly hotels currently available. To find the best prices and deals, simply sort the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel stay in Melrose with your flights and activities through an Expedia package deal.

Find the best attractions near Melrose

Melrose, Florida, is perfect for outdoor enthusiasts and romantic getaways, offering stunning scenery and a variety of attractions. Visitors can explore beautiful lakes, venture into nearby national and state parks, or relax in urban parks. For those seeking a beach experience or vibrant outdoor activities, Melrose provides a delightful escape into nature, making it an ideal destination for travelers looking to enjoy the great outdoors.

  • Santa Fe Lake: Located 3 miles from Melrose, Santa Fe Lake offers a serene escape with its picturesque scenery and sandy beach vibes. It's perfect for a romantic day or a family outing, providing opportunities for swimming, picnicking, and enjoying nature's beauty.
  • Gold Head Branch State Park: Situated 11 miles away, this state park is a haven for adventure lovers. Explore its scenic trails, discover diverse wildlife, and enjoy outdoor activities like hiking, biking, and camping amidst lush landscapes.
  • Lake Como United Methodist Church: About 15 miles from Melrose, this church invites visitors to experience its rich cultural heritage. Attend a service or enjoy the community events that highlight the local traditions and values.

Best time to go to Melrose

The best time to visit Melrose is dependent on what kind of holiday you are seeking. July and August are its hottest month on average. At the time of August, visitor numbers are average and weather is mostly sunny. January is its coolest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January55.8°F (13.2°C)Light RainMostly SunnyAverageSlightly Low
February60.1°F (15.6°C)Light RainMostly SunnyAverageAverage
March64.2°F (17.9°C)Light RainMostly SunnyAverageAverage
April70.2°F (21.2°C)Light RainMostly SunnySlightly HighAverage
May75.6°F (24.2°C)Light RainMostly SunnyAverageSlightly High
June80.1°F (26.7°C)Light RainMostly SunnyAverageAverage
July81.5°F (27.5°C)Light RainMostly SunnySlightly HighSlightly Low
August81.5°F (27.5°C)Light RainMostly SunnyAverageAverage
September78.6°F (25.9°C)Light RainMostly SunnySlightly HighSlightly High
October72.0°F (22.2°C)Light RainMostly SunnySlightly LowSlightly High
November63.9°F (17.7°C)Light RainMostly SunnySlightly LowAverage
December59.9°F (15.5°C)Light RainMostly SunnySlightly LowSlightly Low

The nearest major airports for your trip to Melrose

Traveling to Melrose, Florida, is convenient with three major airports nearby. Jacksonville International Airport (JAX) is 58 miles away, with hotels like the DoubleTree by Hilton Hotel Jacksonville Airport, just 0.3 miles from the airport, and the Hyatt Regency Jacksonville, located 12 miles away. Daytona Beach International Airport (DAB), situated 70 miles from Melrose, offers nearby accommodations such as The Shores Resort & Spa and Daytona Grande Oceanfront Resort, both 4 miles away. Gainesville Regional Airport (GNV) is the closest at 14 miles, featuring hotels like DoubleTree by Hilton Gainesville, 8 miles away, and Hotel Eleo at the University of Florida, just 5 miles from the airport.

Frequently asked questions

What is the best area to stay in Melrose?
The best area to stay in Melrose is directly within the town center, particularly around the intersection of SR 21 and SR 26, as this is where you'll find the most convenient access to local amenities and the lake.Melrose itself is a small, quiet town centered around Melrose Bay on Lake Santa Fe, one of Florida's largest and cleanest lakes. The main activity revolves around the lake, with opportunities for boating, fishing, and enjoying the water. The town center offers a few local eateries and shops, providing a pleasant base for a relaxed stay.Couples looking for a tranquil getaway will find Melrose an excellent fit. The area provides a peaceful setting away from city noise, superb for enjoying nature and quality time together.
When is the best time to go to Melrose?
The best time to visit Melrose, Florida, is during the spring (March to May) and fall (September to November) when the weather is most pleasant.During these seasons, you'll experience mild temperatures and lower humidity, making it ideal for enjoying outdoor activities like exploring the local lakes and nature trails. The spring brings blooming wildflowers, while the fall offers comfortable conditions for fishing, kayaking, or simply relaxing by the water.Melrose is particularly appealing to those looking for a laid-back getaway, away from more crowded tourist destinations.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Melrose.
How much is the nightly rate at a Melrose hotel?
Prices for hotels in Melrose often vary, but you can find a great deal from $66 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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