Title: TOP 10 Hotels in Melrose, FL (from $62) - COMPETITIVE PRICES | Expedia.com [Melrose Travel Guide](https://expedia.com/Melrose.dx3000431362)[Vacation Rentals in Melrose](https://expedia.com/Melrose-Vacation-Rentals.d3000431362.Travel-Guide-VacationRentals)[Flights to Melrose](https://expedia.com/Cheap-Flights-To-Melrose.d3000431362.Travel-Guide-Flights)[Car Rentals in Melrose](https://expedia.com/Car-Rentals-In-Melrose.d3000431362.Car-Rental-Guide)[Melrose Vacation Packages](https://expedia.com/Melrose.d3000431362.Destination-Travel-Guides) ![](https://images.trvl-media.com/place/3000431362/0b90ed1d-67eb-4497-a9f6-f9ac696978e8.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Matt Mateo ![](https://images.trvl-media.com/place/3000431362/0b90ed1d-67eb-4497-a9f6-f9ac696978e8.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Melrose Cabin [](https://www.expedia.com/Hotel-Search?destination=Melrose%2C+Florida%2C+United+States+of+America®ionId=3000431362&latLong=29.70941%2C-82.04982&adults=2&startDate=2026-04-11&d1=2026-04-11&endDate=2026-04-13&d2=2026-04-13&lodging=CABIN) Family friendly [](https://www.expedia.com/Hotel-Search?destination=Melrose%2C+Florida%2C+United+States+of+America®ionId=3000431362&latLong=29.70941%2C-82.04982&adults=2&startDate=2026-04-11&d1=2026-04-11&endDate=2026-04-13&d2=2026-04-13&travelerType=family_friendly) Pool [](https://www.expedia.com/Hotel-Search?destination=Melrose%2C+Florida%2C+United+States+of+America®ionId=3000431362&latLong=29.70941%2C-82.04982&adults=2&startDate=2026-04-11&d1=2026-04-11&endDate=2026-04-13&d2=2026-04-13&amenities=POOL) Pet friendly [](https://www.expedia.com/Hotel-Search?destination=Melrose%2C+Florida%2C+United+States+of+America®ionId=3000431362&latLong=29.70941%2C-82.04982&adults=2&startDate=2026-04-11&d1=2026-04-11&endDate=2026-04-13&d2=2026-04-13&amenities=PETS) Hot tub [](https://www.expedia.com/Hotel-Search?destination=Melrose%2C+Florida%2C+United+States+of+America®ionId=3000431362&latLong=29.70941%2C-82.04982&adults=2&startDate=2026-04-11&d1=2026-04-11&endDate=2026-04-13&d2=2026-04-13&amenities=HOT_TUB) Apart hotel [](https://www.expedia.com/Hotel-Search?destination=Melrose%2C+Florida%2C+United+States+of+America®ionId=3000431362&latLong=29.70941%2C-82.04982&adults=2&startDate=2026-04-11&d1=2026-04-11&endDate=2026-04-13&d2=2026-04-13&lodging=APART_HOTEL) Cottage [](https://www.expedia.com/Hotel-Search?destination=Melrose%2C+Florida%2C+United+States+of+America®ionId=3000431362&latLong=29.70941%2C-82.04982&adults=2&startDate=2026-04-11&d1=2026-04-11&endDate=2026-04-13&d2=2026-04-13&lodging=COTTAGE) Apart­ment [](https://www.expedia.com/Hotel-Search?destination=Melrose%2C+Florida%2C+United+States+of+America®ionId=3000431362&latLong=29.70941%2C-82.04982&adults=2&startDate=2026-04-11&d1=2026-04-11&endDate=2026-04-13&d2=2026-04-13&lodging=APARTMENT) Condo [](https://www.expedia.com/Hotel-Search?destination=Melrose%2C+Florida%2C+United+States+of+America®ionId=3000431362&latLong=29.70941%2C-82.04982&adults=2&startDate=2026-04-11&d1=2026-04-11&endDate=2026-04-13&d2=2026-04-13&lodging=CONDO) ## Check prices for these dates Tonight [Mar 28 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=3000431362&startDate=2026-03-28&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 29 - Mar 30](https://www.expedia.com/Hotel-Search?regionId=3000431362&startDate=2026-03-29&endDate=2026-03-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=3000431362&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=3000431362&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Melrose hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/920000/910300/910208/08745267.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/920000/910300/910208/fc83fe5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking | Bathroom sink](https://images.trvl-media.com/lodging/1000000/920000/910300/910208/79c67c68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Double Bed, Non Smoking | Television](https://images.trvl-media.com/lodging/1000000/920000/910300/910208/cc36dca8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gator Town Inn [](https://www.expedia.com/Gainesville-Hotels-Gator-Town-Inn.h910208.Hotel-Information) Gainesville 7.6/10 Good (855 reviews) "The room was clean and the beds were comfortable. For the quality price, I would recommend this hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angela $53 nightly $60 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Gainesville-Hotels-Gator-Town-Inn.h910208.Hotel-Information) ![Treehouse Suite | Private kitchen | Microwave, coffee/tea maker, electric kettle, toaster](https://images.trvl-media.com/lodging/93000000/92540000/92535400/92535326/02abb060.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Downtown Studio | Street view](https://images.trvl-media.com/lodging/93000000/92540000/92535400/92535326/72ee051a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Repurpose Room | Bathroom | Shower, rainfall showerhead, free toiletries, hair dryer](https://images.trvl-media.com/lodging/93000000/92540000/92535400/92535326/39089dc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/93000000/92540000/92535400/92535326/w997h664x0y3-a53eaa50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Depot Village [](https://www.expedia.com/Gainesville-Hotels-Depot-Village.h92535326.Hotel-Information) Gainesville 9.6/10 Exceptional (110 reviews) "My fav spot to stay in town 💚" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amanda $99 nightly $112 total Apr 1 - Apr 2 Total with taxes and fees [](https://www.expedia.com/Gainesville-Hotels-Depot-Village.h92535326.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/91000000/90150000/90143200/90143200/baab3408.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/91000000/90150000/90143200/90143200/8ccd2f93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds | Free WiFi](https://images.trvl-media.com/lodging/91000000/90150000/90143200/90143200/098782ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/91000000/90150000/90143200/90143200/eea1d68b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Starke by IHG [](https://www.expedia.com/Starke-Hotels-Holiday-Inn-Express-Starke.h90143200.Hotel-Information) Starke 9.6/10 Exceptional (513 reviews) "Facility was very clean and breakfast was very good. Would definitely stay again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sheila $111 nightly $123 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Starke-Hotels-Holiday-Inn-Express-Starke.h90143200.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/10000/8000/7983/f683dfb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8000/7983/e8a54c34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/8000/7983/eb8d0761.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8000/7983/44ce7551.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Palatka Riverfront [](https://www.expedia.com/St-Augustine-Hotels-Quality-Inn-And-Suites-Riverfront.h7983.Hotel-Information) Palatka 8.2/10 Very Good (1,001 reviews) "Great room and good breakfast" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janae $93 nightly $103 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/St-Augustine-Hotels-Quality-Inn-And-Suites-Riverfront.h7983.Hotel-Information) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/125000000/124180000/124177600/124177577/697ed988.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/125000000/124180000/124177600/124177577/b4b21f2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/125000000/124180000/124177600/124177577/91790cb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/125000000/124180000/124177600/124177577/f3e3dc51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hawthorne Angler's Cabin w/ Lake + Dock Access! [](https://www.expedia.com/Hawthorne-Hotels-Hawthorne-Anglers-Cabin-W-Lake-Dock-Access.h124177577.Hotel-Information) Hawthorne $315 nightly $351 total Apr 3 - Apr 4 Total with taxes and fees [](https://www.expedia.com/Hawthorne-Hotels-Hawthorne-Anglers-Cabin-W-Lake-Dock-Access.h124177577.Hotel-Information) ![Deluxe Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/22300/22209/e789f119.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22300/22209/0d7e3d2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22300/22209/63d489bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Non Smoking | Desk, blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/22300/22209/0eff6394.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Gainesville [](https://www.expedia.com/Gainesville-Hotels-Regency-Inn.h22209.Hotel-Information) Gainesville 7.2/10 Good (196 reviews) "We had good staying in this hotel, it is very comfortable and clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alexander $55 nightly $62 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Gainesville-Hotels-Regency-Inn.h22209.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/20000000/19490000/19484600/19484503/0dff4e4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/20000000/19490000/19484600/19484503/19713bd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/20000000/19490000/19484600/19484503/e93e0d3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/20000000/19490000/19484600/19484503/93f8f773.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Gainesville [](https://www.expedia.com/Gainesville-Hotels-Drury-Inn-Suites-Gainesville.h19484503.Hotel-Information) Gainesville 9.6/10 Exceptional (1,412 reviews) "Great place to stay! Would recommend. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle $108 nightly $121 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Gainesville-Hotels-Drury-Inn-Suites-Gainesville.h19484503.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/17300/17274/087f9766.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/17300/17274/51675133.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily self-serve breakfast](https://images.trvl-media.com/lodging/1000000/20000/17300/17274/13f62121.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (Shower Only) | Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/17300/17274/5e1b0ca7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Starke [](https://www.expedia.com/Gainesville-Hotels-Best-Western-Starke.h17274.Hotel-Information) Starke 8.6/10 Excellent (692 reviews) "Very pleasant and helpful staff, clean quiet, comfortable room, easy room access to handicapped room from parking. Good proximity to restaurants and shopping." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marie $107 nightly $119 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Gainesville-Hotels-Best-Western-Starke.h17274.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/910000/903300/903290/253a1423.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/903300/903290/3b6e1844.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/910000/903300/903290/151eb783.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/910000/903300/903290/w851h683x1y0-6723da78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Carpet Inn [](https://www.expedia.com/Gainesville-Hotels-Red-Carpet-Inn.h903290.Hotel-Information) Starke 8.6/10 Excellent (638 reviews) "Clean, inexpensive with a courteous staff. Will stay there again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William $72 nightly $80 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Gainesville-Hotels-Red-Carpet-Inn.h903290.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/440000/439800/439799/c37dfd5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/440000/439800/439799/5c4d5825.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/440000/439800/439799/1c3421f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/440000/439800/439799/3cda58a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Gainesville I-75 Hospital University Area [](https://www.expedia.com/Gainesville-Hotels-Super-8-By-Wyndham-Gainesville.h439799.Hotel-Information) Gainesville 7.6/10 Good (1,002 reviews) "Great place all around" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cadarius $50 nightly $56 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Gainesville-Hotels-Super-8-By-Wyndham-Gainesville.h439799.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/26000000/25010000/25007300/25007284/eace601f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/26000000/25010000/25007300/25007284/7a1f25d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Cabin, 2 Twin Beds, Non Smoking | Bathroom | Free toiletries, towels, toilet paper](https://images.trvl-media.com/lodging/26000000/25010000/25007300/25007284/edf12f39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Cabin, 1 Queen Bed, Non Smoking | Premium bedding, individually decorated, individually furnished](https://images.trvl-media.com/lodging/26000000/25010000/25007300/25007284/da811b1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Yearling Restaurant and Cabins [](https://www.expedia.com/Gainesville-Hotels-Yearling-Restaurant-And-Cabins.h25007284.Hotel-Information) Hawthorne 9.2/10 Wonderful (204 reviews) "I stayed for one night and was happy with my cabin. It was clean and comfortable. The staff was friendly and welcoming, the check in process uncomplicated." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gabriele $139 nightly $156 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Gainesville-Hotels-Yearling-Restaurant-And-Cabins.h25007284.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/27000000/26950000/26940800/26940780/dfb2f417.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/27000000/26950000/26940800/26940780/5247aa46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/27000000/26950000/26940800/26940780/953f268b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception hall](https://images.trvl-media.com/lodging/27000000/26950000/26940800/26940780/6f16a212.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Indigo Gainesville-Celebration Pointe by IHG [](https://www.expedia.com/Gainesville-Hotels-Hotel-Indigo-Gainesville-Celebration-Pointe.h26940780.Hotel-Information) Gainesville 9.0/10 Wonderful (1,002 reviews) "Nice property and location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Linda $112 nightly $126 total Apr 26 - Apr 27 Total with taxes and fees [](https://www.expedia.com/Gainesville-Hotels-Hotel-Indigo-Gainesville-Celebration-Pointe.h26940780.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3080000/3071700/3071695/63174733.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast on weekdays](https://images.trvl-media.com/lodging/4000000/3080000/3071700/3071695/7e5fcb6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3080000/3071700/3071695/11a97479.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/4000000/3080000/3071700/3071695/a2aa59b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Palatka Northwest by IHG [](https://www.expedia.com/St-Augustine-Hotels-Holiday-Inn-Express-Palatka-Northwest.h3071695.Hotel-Information) Palatka 9.2/10 Wonderful (581 reviews) "Great rooms and friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Neil $137 nightly $152 total Apr 26 - Apr 27 Total with taxes and fees [](https://www.expedia.com/St-Augustine-Hotels-Holiday-Inn-Express-Palatka-Northwest.h3071695.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/540000/537800/537785/296e0837.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds, Non Smoking | Desk, laptop workspace, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/1000000/540000/537800/537785/d2f8f8b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/540000/537800/537785/dccaee1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/540000/537800/537785/c1b6992c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Gainesville I-75 [](https://www.expedia.com/Gainesville-Hotels-Quality-Inn-Gainesville-I-75.h537785.Hotel-Information) Gainesville 7.6/10 Good (942 reviews) "The room was lovely and the bedding was very cozy." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debra $77 nightly $86 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Gainesville-Hotels-Quality-Inn-Gainesville-I-75.h537785.Hotel-Information) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98550000/98549900/98549817/6285009b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98550000/98549900/98549817/a1fc30f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98550000/98549900/98549817/633fad00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98550000/98549900/98549817/ee947295.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 3 Mi to UF: Townhome w/ Patio in Gainesville! [](https://www.expedia.com/Gainesville-Hotels-Gainesville-Townhome-Vacation-Rental-3-Mi-To-UF.h98549817.Hotel-Information) Gainesville $273 nightly $304 total Apr 2 - Apr 3 Total with taxes and fees [](https://www.expedia.com/Gainesville-Hotels-Gainesville-Townhome-Vacation-Rental-3-Mi-To-UF.h98549817.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/800000/793600/793525/6c32a14a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/800000/793600/793525/5b627016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking (Pet Friendly) | In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/800000/793600/793525/43de9b15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/800000/793600/793525/a8f32246.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn University [](https://www.expedia.com/Gainesville-Hotels-Comfort-Inn-University.h793525.Hotel-Information) Gainesville 8.4/10 Very Good (1,030 reviews) "The staff are incredibly friendly & helpful. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) arturo $84 nightly $95 total Apr 7 - Apr 8 Total with taxes and fees [](https://www.expedia.com/Gainesville-Hotels-Comfort-Inn-University.h793525.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1290000/1289100/1289043/e387508a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1290000/1289100/1289043/cf87e7bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1290000/1289100/1289043/f5784012.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/2000000/1290000/1289100/1289043/w2878h1920x0y0-ae7e9910.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Gainesville, FL [](https://www.expedia.com/Gainesville-Hotels-Country-Inn-Suites-By-Radisson.h1289043.Hotel-Information) Gainesville 9.2/10 Wonderful (1,737 reviews) "Room was clean, staff was very friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dawn $88 nightly $99 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Gainesville-Hotels-Country-Inn-Suites-By-Radisson.h1289043.Hotel-Information) ![Suite, 1 King Bed, Non Smoking, Refrigerator & Microwave (with Sofabed) | Pillowtop beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/3000000/2390000/2384400/2384393/894b95a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2390000/2384400/2384393/9c79e172.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2390000/2384400/2384393/5ca419d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Accessible, Non Smoking (with Sofabed) | Pillowtop beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/3000000/2390000/2384400/2384393/f760ddb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Waldo Inn and Suites [](https://www.expedia.com/Gainesville-Hotels-Best-Western-Waldo-Inn-And-Suites.h2384393.Hotel-Information) Waldo 8.8/10 Excellent (981 reviews) "Was good … Breakfast was suprising good .. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bill $102 nightly $115 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Gainesville-Hotels-Best-Western-Waldo-Inn-And-Suites.h2384393.Hotel-Information) ![Desk, iron/ironing board, free cribs/infant beds, free rollaway beds](https://images.trvl-media.com/lodging/2000000/1940000/1932400/1932346/70ccd44a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/2000000/1940000/1932400/1932346/cba0289f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1940000/1932400/1932346/e8bf5c2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1940000/1932400/1932346/f7f29b03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn & Suites University/Shands [](https://www.expedia.com/Gainesville-Hotels-Sleep-Inn-Suites-UniversityShands.h1932346.Hotel-Information) Gainesville 8.8/10 Excellent (1,147 reviews) "Great staff, great rooms, great breakfast. Really enjoyed my stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ritchie $84 nightly $95 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Gainesville-Hotels-Sleep-Inn-Suites-UniversityShands.h1932346.Hotel-Information) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2420000/2413900/2413834/3517b621.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2420000/2413900/2413834/9a502df8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/3000000/2420000/2413900/2413834/ad551cb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2420000/2413900/2413834/7e6ff378.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Americas Best Value Inn Starke [](https://www.expedia.com/Gainesville-Hotels-Americas-Best-Value-Inn-Starke.h2413834.Hotel-Information) Starke 7.4/10 Good (553 reviews) "Quiet, cozy, convenient and affordable " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathryn $85 nightly $94 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Gainesville-Hotels-Americas-Best-Value-Inn-Starke.h2413834.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-11&endDate=2026-04-12®ionId=3000431362&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMelrose-Hotels.d3000431362.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMelrose-Hotels.d3000431362.Travel-Guide-Hotels) ## Learn more about Melrose Nestled along Lake Santa Fe, this charming town offers peaceful kayaking and fishing at Melrose Bay Park. Art lovers can browse local galleries and studios, then enjoy fresh farm-to-table dining at the weekend farmers' market. [See all hotels in Melrose](https://www.expedia.com/Hotel-Search?startDate=2026-04-11&endDate=2026-04-12&adults=2®ionId=3000431362) ![](https://images.trvl-media.com/place/3000431362/0b90ed1d-67eb-4497-a9f6-f9ac696978e8.jpg?impolicy=fcrop&w=899&h=675&p=1&q=high) Photo by Matt Mateo ## Top Melrose Hotel Reviews ![Drury Inn & Suites Gainesville](https://images.trvl-media.com/lodging/20000000/19490000/19484600/19484503/0dff4e4a_y.jpg) ### Drury Inn & Suites Gainesville 10/10 Excellent "Clean room, friendly staff and good breakfast options." [](https://expedia.com/Gainesville-Hotels-Drury-Inn-Suites-Gainesville.h19484503.Hotel-Information) ![Hilton University of Florida Conference Center Gainesville](https://images.trvl-media.com/lodging/1000000/480000/475300/475205/50a7bef2_y.jpg) ### Hilton University of Florida Conference Center Gainesville 6/10 Okay "Pro - huge room; location - walking distance to baseball/softball fields. Cons - bed was very hard and uncomfortable. Also seemed to be uneven. Jackhammering into the wall in the morning woke me up. " [](https://expedia.com/Gainesville-Hotels-Hilton-University-Of-Florida-Conference-Center-Gainesville.h475205.Hotel-Information) ![Quality Inn & Suites Palatka Riverfront](https://images.trvl-media.com/lodging/1000000/10000/8000/7983/f683dfb7_y.jpg) ### Quality Inn & Suites Palatka Riverfront 10/10 Excellent "Good " [](https://expedia.com/St-Augustine-Hotels-Quality-Inn-And-Suites-Riverfront.h7983.Hotel-Information) ![Super 8 by Wyndham Gainesville I-75 Hospital University Area](https://images.trvl-media.com/lodging/1000000/440000/439800/439799/c37dfd5e_y.jpg) ### Super 8 by Wyndham Gainesville I-75 Hospital University Area 2/10 Terrible "I was accused of taking towels and charged for them. Also charged a fee for a safe I did not use." [](https://expedia.com/Gainesville-Hotels-Super-8-By-Wyndham-Gainesville.h439799.Hotel-Information) ![Sleep Inn & Suites University/Shands](https://images.trvl-media.com/lodging/2000000/1940000/1932400/1932346/70ccd44a_y.jpg) ### Sleep Inn & Suites University/Shands 8/10 Good "This property is a little under-rated if you ask me. It's very clean, the staff is amazing, the little extras like popcorn and cookies make it feel exta special. The drawback, it's older and sits behind a newer, flashier lioking Drury Inn. The price is definietely right. Parking was easy. And the beds are comfy! Breakfast was good, too. " [](https://expedia.com/Gainesville-Hotels-Sleep-Inn-Suites-UniversityShands.h1932346.Hotel-Information) ![HOM Hotel Gainesville, SureStay Collection by Best Western](https://images.trvl-media.com/lodging/1000000/210000/200800/200755/8a6fa57c_y.jpg) ### HOM Hotel Gainesville, SureStay Collection by Best Western 6/10 Okay "Staff belligerent after just one mild criticism. Someone also entered my room & left it OPEN, no less, with “respect privacy” sign on the door. No clear delineation between lobby & breakfasting area for people with dogs. Bathroom super-functional, beds & pillows comfortable. " [](https://expedia.com/Gainesville-Hotels-HOM-Hotel-Gainesville.h200755.Hotel-Information) ![Country Inn & Suites by Radisson, Gainesville, FL](https://images.trvl-media.com/lodging/2000000/1290000/1289100/1289043/e387508a_y.jpg) ### Country Inn & Suites by Radisson, Gainesville, FL 10/10 Excellent "It's always served me well. I stay here for the Florida Gators football game. Great place and good breakfast. " [](https://expedia.com/Gainesville-Hotels-Country-Inn-Suites-By-Radisson.h1289043.Hotel-Information) ![SpringHill Suites by Marriott Gainesville](https://images.trvl-media.com/lodging/2000000/1540000/1531600/1531530/6fa20102_y.jpg) ### SpringHill Suites by Marriott Gainesville 10/10 Excellent "Hotel was great, friendly staff. " [](https://expedia.com/Gainesville-Hotels-SpringHill-Suites-By-Marriott-Gainesville.h1531530.Hotel-Information) ![Comfort Inn University](https://images.trvl-media.com/lodging/1000000/800000/793600/793525/6c32a14a_y.jpg) ### Comfort Inn University 10/10 Excellent "The staff was very helpful and really nice. Property was clean and well kept" [](https://expedia.com/Gainesville-Hotels-Comfort-Inn-University.h793525.Hotel-Information) ## More cheap stays in Melrose ![Red Roof Inn PLUS+ Gainesville](https://images.trvl-media.com/lodging/1000000/90000/82700/82677/5b4e3b0e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Red Roof Inn PLUS+ Gainesville 3500 Southwest 42nd St Gainesville FL $74 nightly $83 total Mar 29 - Mar 30 Total with taxes and fees 7.4/10 Good! (1,254 reviews) [](https://expedia.com/Gainesville-Hotels-Red-Roof-Inn-PLUS-Gainesville.h82677.Hotel-Information) ![HOM Hotel Gainesville, SureStay Collection by Best Western](https://images.trvl-media.com/lodging/1000000/210000/200800/200755/8a6fa57c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### HOM Hotel Gainesville, SureStay Collection by Best Western 3905 Sw 43Rd St Gainesville FL $77 nightly $87 total Apr 5 - Apr 6 Total with taxes and fees 8.4/10 Very Good! (1,860 reviews) [](https://expedia.com/Gainesville-Hotels-HOM-Hotel-Gainesville.h200755.Hotel-Information) ![Quality Inn Gainesville near University](https://images.trvl-media.com/lodging/1000000/10000/1300/1220/a7376ef0_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn Gainesville near University 2435 Sw 13th Street Gainesville FL $79 nightly $89 total Apr 5 - Apr 6 Total with taxes and fees 7/10 Good! (1,000 reviews) [](https://expedia.com/Gainesville-Hotels-Quality-Inn-University.h1220.Hotel-Information) ![Sleep Inn & Suites University/Shands](https://images.trvl-media.com/lodging/2000000/1940000/1932400/1932346/70ccd44a_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Sleep Inn & Suites University/Shands 4110 SW 40th Boulevard Gainesville FL $84 nightly $95 total Apr 5 - Apr 6 Total with taxes and fees 8.8/10 Excellent! (1,147 reviews) [](https://expedia.com/Gainesville-Hotels-Sleep-Inn-Suites-UniversityShands.h1932346.Hotel-Information) ![Quality Inn & Suites Palatka Riverfront](https://images.trvl-media.com/lodging/1000000/10000/8000/7983/f683dfb7_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn & Suites Palatka Riverfront 201 N 1st Street Palatka FL $93 nightly $103 total Apr 12 - Apr 13 Total with taxes and fees 8.2/10 Very Good! (1,001 reviews) [](https://expedia.com/St-Augustine-Hotels-Quality-Inn-And-Suites-Riverfront.h7983.Hotel-Information) ![Comfort Suites Gainesville near University](https://images.trvl-media.com/lodging/55000000/54140000/54138200/54138132/95cd6e6a_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Comfort Suites Gainesville near University 2603 SW 13TH STREET Gainesville FL $93 nightly $104 total Apr 19 - Apr 20 Total with taxes and fees 9.2/10 Wonderful! (1,279 reviews) [](https://expedia.com/Gainesville-Hotels-Comfort-Suites-Gainesville-Near-University.h54138132.Hotel-Information) ## Hotels in Melrose with star-rating ![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg) 4 Star Hotels 6 properties [](https://expedia.com/4Star-Melrose-Hotels.s40-0-d3000431362.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 82 properties [](https://expedia.com/3Star-Melrose-Hotels.s30-0-d3000431362.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 49 properties [](https://expedia.com/2Star-Melrose-Hotels.s20-0-d3000431362.Travel-Guide-Filter-Hotels) ## Find out more about Melrose ### Top reasons to visit Melrose - **Outdoor Adventures:** Melrose is ideal for exploring beautiful lakes, national and state parks, and urban parks, perfect for nature enthusiasts. - **Charming Atmosphere:** The friendly vibe and inviting main streets make Melrose a great destination for romantic getaways or family fun. - **Unique Experiences:** Don't miss whale watching, which offers a memorable touch to your vacation in this quaint town. - **Variety of Accommodations:** Choose from cozy motels to inviting hotels, catering to diverse vacation needs. - **Accessible Location:** Just a short drive from Gainesville and Palatka, Melrose is conveniently located for easy exploration. ### Find great hotels near Melrose Discover a range of hotel accommodations in Melrose, Florida, perfect for your vacation needs. Whether you're seeking a pet-friendly stay, a comfortable spot for business travel, or an adventure-filled experience, Melrose offers a variety of options. From cozy motels to inviting hotels, you'll find the perfect room to make your visit enjoyable and memorable. - **[Hotel Eleo at the University of Florida: ](https://www.expedia.com/Gainesville-Hotels-Hotel-Eleo-At-The-University-Of-Florida.h52054135.Hotel-Information)** A 3.5-star hotel with an impressive guest rating of 9.4, Hotel Eleo at the University of Florida is a charming retreat located 18 miles from Melrose. This property stands out for its pet-friendly atmosphere, making it an excellent choice for travelers who wish to bring their furry companions along. With a variety of pet amenities, including a fee-waived service animal policy, guests can feel at home while enjoying the university's vibrant surroundings. The hotel offers a stylish blend of modern comfort and Southern hospitality, creating an inviting space for both relaxation and exploration. - **[Hyatt Place Gainesville Downtown: ](https://www.expedia.com/Gainesville-Hotels-Hyatt-Place-Gainesville-Downtown.h78547624.Hotel-Information)** A 3-star hotel with a notable guest rating of 9.2, Hyatt Place Gainesville Downtown is situated 17 miles from Melrose and caters to families and business travelers alike. This property features a unique hot spring theme, with nearby access to natural hot springs for a rejuvenating experience. Amenities for children, such as free cribs and pool toys, ensure that families can enjoy their stay without compromising comfort. The hotel's modern design and welcoming atmosphere make it an ideal base for exploring the vibrant downtown area while enjoying quality time with loved ones. - **[Hampton Inn & Suites Gainesville-Downtown: ](https://www.expedia.com/Gainesville-Hotels-Hampton-Inn-Suites-Gainesville-Downtown.h2873991.Hotel-Information)** A budget-friendly option with a guest rating of 8.6, Hampton Inn & Suites Gainesville-Downtown is located 17 miles from Melrose. This hotel is perfect for travelers seeking a pet-friendly environment while balancing business and leisure. It has a pet policy that accommodates various sizes, with fees waived for service animals. Guests will appreciate the comfortable rooms, complimentary breakfast, and convenient access to downtown, making it a practical choice for those looking to stay connected while enjoying the local attractions. ### Where to stay in and around Melrose Melrose, Florida, offers a charming escape with its friendly atmosphere and outdoor allure, perfect for romantic getaways or family adventures. Just a short drive from nearby cities like Gainesville and Palatka, you'll find local amenities and inviting main streets to explore. Enjoy scenic views and summer staycations that highlight the beauty of this hidden gem, making it an ideal destination for relaxation and discovery. - **[Earleton: ](https://www.expedia.com/Earleton-Hotels.d3000345210.Travel-Guide-Hotels)** Nestled just 3 miles from Melrose, Earleton is a charming city that offers a delightful outdoor experience, making it a popular choice for those seeking scenic views and romantic getaways. Visitors can explore its beautiful recreational areas, indulge in adventure activities, and even dive into underwater sports. The proximity to stunning lakes, rivers, and a national state park enhances its appeal, providing ample opportunities for nature lovers to immerse themselves in the great outdoors. The best time to visit is during the peak months of March, August, and November, when the weather is ideal for outdoor adventures. - **[Grandin: ](https://www.expedia.com/Grandin-Hotels.d553248635975871409.Travel-Guide-Hotels)** Located close to Melrose, Grandin is a quaint village known for its picturesque scenery and romantic atmosphere. Travelers flock here for its serene charm, with the local lakes serving as perfect spots for relaxation and reflection. The village provides a peaceful escape from the hustle and bustle, making it an ideal destination for couples and outdoor enthusiasts alike. Similar to Earleton, Grandin experiences peak visitor numbers in March, August, and November, making these months perfect for a visit to enjoy its natural beauty. - **[Keystone Heights: ](https://www.expedia.com/Keystone-Heights-Hotels.d6351663.Travel-Guide-Hotels)** A mere 5 miles from Melrose, Keystone Heights is a unique city characterized by its island-like features. This vibrant locale is a haven for outdoor enthusiasts, offering various recreational areas and adventure activities, including underwater sports. Visitors are drawn to its breathtaking lakes, rivers, and the nearby national state park, which provide stunning backdrops for exploration and relaxation. Keystone Heights sees peak travel seasons in February to March and December, making it an excellent choice for tourists looking to connect with nature and enjoy a romantic getaway. ### Things to do near Melrose Melrose, Florida, is perfect for outdoor adventures and romantic getaways. Visitors can enjoy a range of activities, including exploring the beautiful recreational areas, indulging in educational experiences, and hitting the golf courses. While shopping opportunities abound, don't miss the chance for unique experiences like whale watching, which adds a memorable touch to your vacation in this charming town. **Shopping** In Melrose, enjoy local shops offering unique gifts and souvenirs. If you're up for a drive, visit the Gainesville Mall, about 15 miles away, which features a variety of national retailers and dining options for a more extensive shopping experience. **Recreation** Haile Plantation Golf and Country Club offers a luxurious golfing experience just 25 miles from Melrose, featuring pristine greens and upscale amenities. Similarly, Magnolia Point Golf and Country Club, located 29 miles away, provides an elegant atmosphere perfect for relaxation and recreation amidst beautiful landscapes. **Adventure** Explore the serene waters of Lake Santa Fe for kayaking and fishing, or hike the scenic trails at the nearby San Felasco Hammock Preserve State Park for a chance to spot local wildlife. For a thrilling experience, try horseback riding at local stables for a fun adventure. **Nightlife** Explore the vibrant nightlife in Melrose by visiting The Melrose Community Center for local events and gatherings. For a laid-back evening, check out the Melrose Pub, where you can enjoy a cold drink and mingle with friendly locals in a cozy atmosphere. \*Distances are measured in a straight line; actual driving distances may vary depending on the route. ### Booking tips and Expedia advantages for Melrose - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay in Melrose are July and December to January, where the prices are slightly lower. This is in comparison to May and September to October, where prices are slightly higher. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay in Melrose is Tuesday. The most expensive day to stay in Melrose is Saturday. - **Find cheap hotels on Expedia:** Utilize Expedia’s search tool to customize your travel preferences, such as your budget, desired location, and preferred hotel type. For instance, selecting the Eco-certified option will showcase sustainable and environmentally friendly hotels currently available. To find the best prices and deals, simply sort the price filter from lowest to highest. - **Consider bundling your trip:** You can save money by combining your hotel stay in Melrose with your flights and activities through an Expedia package deal. ### Find the best attractions near Melrose Melrose, Florida, is perfect for outdoor enthusiasts and romantic getaways, offering stunning scenery and a variety of attractions. Visitors can explore beautiful lakes, venture into nearby national and state parks, or relax in urban parks. For those seeking a beach experience or vibrant outdoor activities, Melrose provides a delightful escape into nature, making it an ideal destination for travelers looking to enjoy the great outdoors. - **[Santa Fe Lake: ](https://www.expedia.com/Santa-Fe-Lake-Hotels.0-l553248635976194916-0.Travel-Guide-Filter-Hotels)** Located 3 miles from Melrose, Santa Fe Lake offers a serene escape with its picturesque scenery and sandy beach vibes. It's perfect for a romantic day or a family outing, providing opportunities for swimming, picnicking, and enjoying nature's beauty. - **[Gold Head Branch State Park: ](https://www.expedia.com/Gold-Head-Branch-State-Park-Hotels.0-l6184480-0.Travel-Guide-Filter-Hotels)** Situated 11 miles away, this state park is a haven for adventure lovers. Explore its scenic trails, discover diverse wildlife, and enjoy outdoor activities like hiking, biking, and camping amidst lush landscapes. - **[Lake Como United Methodist Church: ](https://www.expedia.com/Lake-Como-United-Methodist-Church-Hotels.0-l553248621532666698-0.Travel-Guide-Filter-Hotels)** About 15 miles from Melrose, this church invites visitors to experience its rich cultural heritage. Attend a service or enjoy the community events that highlight the local traditions and values. ### Best time to go to Melrose The best time to visit Melrose is dependent on what kind of holiday you are seeking. July and August are its hottest month on average. At the time of August, visitor numbers are average and weather is mostly sunny. January is its coolest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain. | **![calendar](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | ---------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------- | | January | 55.8°F (13.2°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | February | 60.1°F (15.6°C) | Light Rain | Mostly Sunny | Average | Average | | March | 64.2°F (17.9°C) | Light Rain | Mostly Sunny | Average | Average | | April | 70.2°F (21.2°C) | Light Rain | Mostly Sunny | Slightly High | Average | | May | 75.6°F (24.2°C) | Light Rain | Mostly Sunny | Average | Slightly High | | June | 80.1°F (26.7°C) | Light Rain | Mostly Sunny | Average | Average | | July | 81.5°F (27.5°C) | Light Rain | Mostly Sunny | Slightly High | Slightly Low | | August | 81.5°F (27.5°C) | Light Rain | Mostly Sunny | Average | Average | | September | 78.6°F (25.9°C) | Light Rain | Mostly Sunny | Slightly High | Slightly High | | October | 72.0°F (22.2°C) | Light Rain | Mostly Sunny | Slightly Low | Slightly High | | November | 63.9°F (17.7°C) | Light Rain | Mostly Sunny | Slightly Low | Average | | December | 59.9°F (15.5°C) | Light Rain | Mostly Sunny | Slightly Low | Slightly Low | ### The nearest major airports for your trip to Melrose Traveling to Melrose, Florida, is convenient with three major airports nearby. Jacksonville International Airport ([JAX](https://www.expedia.com/Jacksonville-Intl-Airport-Hotels.0-aJAX-0.Travel-Guide-Filter-Hotels)) is 58 miles away, with hotels like the [DoubleTree by Hilton Hotel Jacksonville Airport](https://www.expedia.com/Jacksonville-Hotels-DoubleTree-By-Hilton-Hotel-Jacksonville-Airport.h117340.Hotel-Information), just 0.3 miles from the airport, and the [Hyatt Regency Jacksonville](https://www.expedia.com/Jacksonville-Hotels-Hyatt-Regency-Jacksonville.h563167.Hotel-Information), located 12 miles away. Daytona Beach International Airport ([DAB](https://www.expedia.com/Daytona-Beach-Intl-Airport-Hotels.0-aDAB-0.Travel-Guide-Filter-Hotels)), situated 70 miles from Melrose, offers nearby accommodations such as [The Shores Resort & Spa](https://www.expedia.com/Daytona-Beach-Hotels-The-Shores-Resort-Spa.h15752.Hotel-Information) and [Daytona Grande Oceanfront Resort](https://www.expedia.com/Daytona-Beach-Hotels-Daytona-Grande-Oceanfront-Resort.h61630218.Hotel-Information), both 4 miles away. Gainesville Regional Airport ([GNV](https://www.expedia.com/Gainesville-Regional-Airport-Hotels.0-aGNV-0.Travel-Guide-Filter-Hotels)) is the closest at 14 miles, featuring hotels like [DoubleTree by Hilton Gainesville](https://www.expedia.com/Gainesville-Hotels-DoubleTree-By-Hilton-Gainesville.h49617.Hotel-Information), 8 miles away, and [Hotel Eleo at the University of Florida](https://www.expedia.com/Gainesville-Hotels-Hotel-Eleo-At-The-University-Of-Florida.h52054135.Hotel-Information), just 5 miles from the airport. ## Frequently asked questions ### What is the best area to stay in Melrose? > Melrose itself is a small, quiet town centered around Melrose Bay on Lake Santa Fe, one of Florida's largest and cleanest lakes. The main activity revolves around the lake, with opportunities for boating, fishing, and enjoying the water. The town center offers a few local eateries and shops, providing a pleasant base for a relaxed stay. > > > Couples looking for a tranquil getaway will find Melrose an excellent fit. The area provides a peaceful setting away from city noise, superb for enjoying nature and quality time together. ### When is the best time to go to Melrose? > During these seasons, you'll experience mild temperatures and lower humidity, making it ideal for enjoying outdoor activities like exploring the local lakes and nature trails. The spring brings blooming wildflowers, while the fall offers comfortable conditions for fishing, kayaking, or simply relaxing by the water. > > > Melrose is particularly appealing to those looking for a laid-back getaway, away from more crowded tourist destinations. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Melrose hotel booking with Expedia? > \*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo. ### How much is the nightly rate at a Melrose hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Earleton Hotels ](https://www.expedia.com/Earleton-Hotels.d3000345210.Travel-Guide-Hotels) - [Guest Houses in Earleton ](https://www.expedia.com/Earleton-Guest-Houses.d3000345210-aaGuestHouses.Travel-Guide-Accommodation) - [Cabin Rentals in Earleton ](https://www.expedia.com/Earleton-Cabins.d3000345210-aaCabins.Travel-Guide-Accommodation) - [3 Star Hotels in Earleton ](https://www.expedia.com/3Star-Earleton-Hotels.s30-0-d3000345210.Travel-Guide-Filter-Hotels) - [B&B in Earleton ](https://www.expedia.com/Earleton-Bed-And-Breakfast.d3000345210-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Condo Rentals in Earleton ](https://www.expedia.com/Earleton-Condos.d3000345210-aaCondos.Travel-Guide-Accommodation) - [Cottages in Earleton ](https://www.expedia.com/Earleton-Cottages.d3000345210-aaCottages.Travel-Guide-Accommodation) - 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