Photo by Matt Mateo

Find hotels in Melrose, FL from $75

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Our top choices for Melrose hotels

Holiday Inn Express Starke by IHG

Holiday Inn Express Starke by IHG
2.5 star property
Starke
9.6 out of 10, Exceptional, (407)
"Check in staff were great. Breakfast area was kept clean and stocked. iI’s the same holiday inn express breakfast served at all locations. Nice hotel"
United States
Stacy
$89 nightly
The price is $99
Jan 4 - Jan 5, 2026
Total with taxes and fees
Holiday Inn Express Starke by IHG

Quality Inn & Suites Palatka Riverfront

Quality Inn & Suites Palatka Riverfront
2.5 star property
Palatka
8.2 out of 10, Very Good, (1001)
"We like the location on the river. Nice grounds. Friendly staff."
United States
Judy
$91 nightly
The price is $101
Jan 11 - Jan 12, 2026
Total with taxes and fees
Quality Inn & Suites Palatka Riverfront

Hampton Inn Palatka

Hampton Inn Palatka
2.5 star property
Palatka
9.2 out of 10, Wonderful, (633)
"The front desk person at check in was very nice and made check in easy. "
United States
Kathleen
$116 nightly
The price is $129
Jan 2 - Jan 3, 2026
Total with taxes and fees
Hampton Inn Palatka

HOM Hotel Gainesville, SureStay Collection by Best Western

HOM Hotel Gainesville, SureStay Collection by Best Western
2.5 star property
Gainesville
8.4 out of 10, Very Good, (1803)
"Awesome place to stay."
United States
Aristeo
$76 nightly
The price is $86
Jan 26 - Jan 27, 2026
Total with taxes and fees
HOM Hotel Gainesville, SureStay Collection by Best Western

Comfort Suites Gainesville near University

Comfort Suites Gainesville near University
2.5 star property
Gainesville
9.2 out of 10, Wonderful, (1160)
"Great staff, clean room"
United States
Akbar
$84 nightly
The price is $95
Dec 28 - Dec 29
Total with taxes and fees
Comfort Suites Gainesville near University

Country Inn & Suites by Radisson, Gainesville, FL

Country Inn & Suites by Radisson, Gainesville, FL
3.0 star property
Gainesville
9.2 out of 10, Wonderful, (1636)
"Quiet and clean overnight stay, we will be back , breakfast was good . "
United States
Ralph
$90 nightly
The price is $101
Jan 25 - Jan 26, 2026
Total with taxes and fees
Country Inn & Suites by Radisson, Gainesville, FL

Best Western Waldo Inn and Suites

Best Western Waldo Inn and Suites
2.5 star property
Waldo
8.8 out of 10, Excellent, (953)
"Great stay"
United States
Cathy
$102 nightly
The price is $115
Jan 3 - Jan 4, 2026
Total with taxes and fees
Best Western Waldo Inn and Suites

Hampton Inn Gainesville

Hampton Inn Gainesville
2.5 star property
Gainesville
8.8 out of 10, Excellent, (988)
"Room was super clean, the staff was very nice. The breakfast was very good! "
United States
Chad
$73 nightly
The price is $82
Jan 2 - Jan 3, 2026
Total with taxes and fees
Hampton Inn Gainesville

Hyatt Place Gainesville Downtown

Hyatt Place Gainesville Downtown
3.0 star property
Downtown Gainesville
9.2 out of 10, Wonderful, (1102)
"Great location great staff great experience I have stayed at the hotel before multiple times an again."
United States
Charles
$89 nightly
The price is $100
Dec 28 - Dec 29
Total with taxes and fees
Hyatt Place Gainesville Downtown

Comfort Inn University

Comfort Inn University
2.5 star property
Gainesville
8.2 out of 10, Very Good, (1009)
"Clean room, friendly and attentive staff, very conveniently located."
United States
Omar
$82 nightly
The price is $92
Jan 25 - Jan 26, 2026
Total with taxes and fees
Comfort Inn University

Sleep Inn & Suites University/Shands

Sleep Inn & Suites University/Shands
2.5 star property
Gainesville
8.8 out of 10, Excellent, (1052)
"Nice breakfast, clean roim"
United States
Tracy
$79 nightly
The price is $89
Jan 9 - Jan 10, 2026
Total with taxes and fees
Sleep Inn & Suites University/Shands

Holiday Inn Express Palatka Northwest by IHG

Holiday Inn Express Palatka Northwest by IHG
2.5 star property
Palatka
9.2 out of 10, Wonderful, (566)
"Great hotel "
United States
IVORY
$127 nightly
The price is $141
Dec 28 - Dec 29
Total with taxes and fees
Holiday Inn Express Palatka Northwest by IHG

Red Roof Inn PLUS+ Gainesville

Red Roof Inn PLUS+ Gainesville
2.5 star property
Gainesville
7.4 out of 10, Good, (1229)
"Just drove through and needed a place to stay seems decent!"
United States
Jordan
$67 nightly
The price is $75
Dec 28 - Dec 29
Total with taxes and fees
Red Roof Inn PLUS+ Gainesville

Red Carpet Inn

Red Carpet Inn
2.0 star property
Starke
8.6 out of 10, Excellent, (623)
"clean room and attentive staff"
United States
Scott
$69 nightly
The price is $77
Jan 4 - Jan 5, 2026
Total with taxes and fees
Red Carpet Inn

Soho Inn Waldo

Soho Inn Waldo
2.0 star property
Waldo
$70 nightly
The price is $79
Dec 28 - Dec 29
Total with taxes and fees
Soho Inn Waldo

Super 8 by Wyndham Gainesville I-75 Hospital University Area

Super 8 by Wyndham Gainesville I-75 Hospital University Area
2.0 star property
Gainesville
7.4 out of 10, Good, (1002)
"Awesome stay!"
United States
Phillip
$50 nightly
The price is $56
Dec 29 - Dec 30
Total with taxes and fees
Super 8 by Wyndham Gainesville I-75 Hospital University Area

Best Western Starke

Best Western Starke
2.5 star property
Starke
8.6 out of 10, Excellent, (665)
"staff was great but construction was noisy."
United States
Duane
$79 nightly
The price is $88
Jan 4 - Jan 5, 2026
Total with taxes and fees
Best Western Starke

Hampton Inn & Suites Gainesville-Downtown

Hampton Inn & Suites Gainesville-Downtown
3.0 star property
Downtown Gainesville
8.6 out of 10, Excellent, (1001)
"Love staying here!!!"
United States
Michael
$89 nightly
The price is $101
Jan 2 - Jan 3, 2026
Total with taxes and fees
Hampton Inn & Suites Gainesville-Downtown

DoubleTree by Hilton Gainesville

DoubleTree by Hilton Gainesville
4.0 star property
Gainesville
7.8 out of 10, Good, (1002)
"Friendly staff, clean hotel. The kids enjoyed the welcome cookie. "
United States
Janelle
$84 nightly
The price is $95
Jan 4 - Jan 5, 2026
Total with taxes and fees
DoubleTree by Hilton Gainesville

Hilton Garden Inn Gainesville

Hilton Garden Inn Gainesville
3.0 star property
Gainesville
8.8 out of 10, Excellent, (1004)
"Great stay "
United States
Adriana
$97 nightly
The price is $110
Jan 5 - Jan 6, 2026
Total with taxes and fees
Hilton Garden Inn Gainesville
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Learn more about Melrose

Nestled along Lake Santa Fe, this charming town offers peaceful kayaking and fishing at Melrose Bay Park. Art lovers can browse local galleries and studios, then enjoy fresh farm-to-table dining at the weekend farmers' market.

Melrose, FL
Lake Santa Fe
Photo by Matt Mateo
Open Photo by Matt Mateo

Top Melrose Hotel Reviews

More cheap stays in Melrose

Hotels in Melrose with star-rating

Find out more about Melrose

Top reasons to visit Melrose

  • Outdoor Adventures: Melrose is a paradise for outdoor enthusiasts, featuring beautiful lakes and scenic hiking trails in nearby parks.
  • Charming Neighborhoods: Experience the warm atmosphere of friendly locals in picturesque towns surrounding Melrose.
  • Family-Friendly Activities: Enjoy engaging recreational activities suitable for families, ensuring fun for all ages.
  • Variety of Accommodations: Choose from diverse lodging options, including pet-friendly motels and luxury hotels.
  • Vibrant Shopping: Explore local shopping experiences, including the nearby Santee Alley for unique finds.

Find great hotels near Melrose

Discover a variety of hotel accommodations in Melrose, Florida, catering to every type of traveler. Whether you're seeking a pet-friendly motel for a family vacation or a business-themed hotel, Melrose offers a range of options. Enjoy comfortable stays with essential amenities while exploring the charm of this quaint area. Check out reviews to find the best hotels that suit your needs and create lasting memories during your visit.

  • Hotel Eleo at the University of Florida: Nestled 18 miles from Melrose, Hotel Eleo presents a sophisticated atmosphere ideal for business travelers. This 3.5-star hotel combines modern design with an academic vibe, offering a unique experience for guests looking to blend work and leisure. The property features a range of business amenities, including flexible meeting spaces and a fully-equipped business center, ensuring that all professional needs are met. Guests appreciate the upscale accommodations and convenient location near the University of Florida, making it perfect for those visiting for conferences or university events.
  • Holiday Inn Gainesville - University Center by IHG: Situated 18 miles away from Melrose, this 3-star hotel is a versatile choice for travelers seeking a blend of business and leisure. With a golf-themed ambiance, guests can enjoy golfing experiences alongside modern business facilities, including a 24-hour business center and meeting rooms. The hotel is also pet-friendly, accommodating furry companions with specific policies. Its convenient location near the University of Florida makes it an attractive option for both professionals and families looking to enjoy local attractions while maintaining a productive stay.
  • Hampton Inn & Suites Gainesville-Downtown: Located 17 miles from Melrose, the Hampton Inn & Suites Gainesville-Downtown is a welcoming haven for LGBTQIA travelers and business guests alike. This hotel features a vibrant atmosphere with pet-friendly policies, along with essential business amenities such as meeting rooms and a business center. Its affiliation with LGBTQI travel guides ensures an inclusive environment. Guests can unwind in comfortable accommodations while exploring the vibrant downtown area, making it an excellent choice for both work and play.

Where to stay near Melrose

Melrose, Florida, offers a charming blend of outdoor adventures and romantic getaways. Explore nearby picturesque towns and enjoy the warm atmosphere created by friendly locals. Families can indulge in fun activities, while those looking for a touch of luxury will find delightful options. Don't miss the vibrant shopping experiences, including Santee Alley, just a short drive away. With its scenic beauty and welcoming neighborhoods, Melrose is an ideal base for your vacation explorations.

  • Earleton: Nestled just 3 miles from Melrose, Earleton offers a charming escape for those seeking outdoor adventures and scenic beauty. This small city is characterized by its stunning lakes, rivers, and water features, making it a haven for nature lovers. Visitors can enjoy various recreational activities, from hiking to fishing, while the romantic ambiance provides a perfect backdrop for couples. With its welcoming community and serene surroundings, Earleton promises a delightful travel experience year-round, especially in March, August, and November.
  • Keystone Heights: Located 5 miles from Melrose, Keystone Heights is a picturesque city with a unique island-like charm. Known for its lush landscapes and outdoor activities, it attracts travelers looking for scenic beauty and adventure. With nearby lakes, rivers, and a national state park, visitors can indulge in everything from hiking and swimming to underwater sports. The peak travel seasons in February to March and December highlight the area's appeal as a romantic getaway, allowing visitors to immerse themselves in nature’s tranquility.
  • Lake Geneva: Just 5 miles away from Melrose, the quaint village of Lake Geneva is a perfect spot for outdoor enthusiasts and those in search of scenic vistas. The area is known for its recreational facilities, resorts, and entertainment arenas, making it an ideal destination for relaxation and fun. Surrounded by beautiful lakes and rivers, visitors can explore theme parks and enjoy various activities that cater to families and couples alike. With peak visitor seasons in March, August, and November, Lake Geneva invites you to create unforgettable memories against a stunning natural backdrop.

Things to do near Melrose

Melrose, Florida, is perfect for outdoor enthusiasts and those seeking a romantic getaway. Visitors can explore scenic hiking trails, enjoy exciting rides at nearby theme parks, and participate in engaging games at local recreational areas. Whether you're looking for a relaxing resort experience or educational activities, Melrose offers a variety of attractions to make your vacation memorable.

Shopping

In Melrose, you can visit the Waldo Farmers Market, just 10 miles away, offering a charming local vibe with fresh produce and unique goods. If you're up for a drive, explore Oaks Mall, 22 miles away, featuring a wide range of shops and entertainment options.

Recreation

Ironwood Golf Course offers a picturesque golfing experience with its lush greens and outdoor ambiance, perfect for sports enthusiasts. Nearby, Bivens Arm Nature Park provides a tranquil setting for relaxation and wellness, featuring scenic trails and serene surroundings. Starke Golf and Country Club also invites you to enjoy the sport in a beautiful outdoor setting.

Adventure

Experience the thrill of high-speed racing at Gainesville Raceway, located 14 miles from Melrose, where the excitement of motorsports fuels your adrenaline. For a family-friendly outdoor adventure, visit Kate's Fish Camp, also 14 miles away, offering a perfect blend of nature and fun. Hike the scenic Florida National Scenic Trail, 17 miles from Melrose, for breathtaking views and outdoor exploration.

Nightlife

Experience the vibrant nightlife in Melrose by visiting the Hippodrome State Theatre for captivating performances or catch a film at Regal Royal Park for a cozy movie night. For more culture and entertainment, the Curtis M. Phillips Center offers a delightful evening filled with romance and family-friendly vibes.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Melrose

To save money during your trip to Melrose, consider visiting in July or the December to January period when hotel prices drop. Booking on a Monday can also help you avoid the Saturday price spike. Use Expedia to find budget-friendly accommodations by sorting options from lowest to highest price, and consider eco-certified hotels for sustainability. Combine your hotel, flights, and activities for additional savings with Expedia packages. Joining Expedia's One Key membership can unlock exclusive discounts and rewards, maximizing your travel budget.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Melrose are July and December to January, where the prices are slightly lower. This is in comparison to May and September to October, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Melrose is Monday. The most expensive day to stay in Melrose is Saturday.
  • Find cheap hotels on Expedia: Expedia's search tool lets you customize your travel experience by selecting your budget, desired location, and additional preferences. You can easily arrange your search results from the lowest to highest prices, ensuring you find the most affordable hotel options first. Additionally, you have the ability to narrow down your choices by hotel type; for instance, if you check the Eco-certified filter, you'll see a selection of sustainable and environmentally-friendly hotels that you can book.
  • Consider bundling your trip: You can save money by combining your hotel stay in Melrose with your flights and activities when you book an Expedia package.
  • Become a One Key member: Join Expedia's One Key membership program for exclusive discounts and deals on hotel bookings. You can also earn OneKeyCash to use on future selected hotels.

Find the best attractions near Melrose

Melrose, Florida, is perfect for outdoor enthusiasts and those seeking a romantic getaway. Visitors can explore beautiful lakes, national and state parks, and urban parks, all showcasing the area's scenic beauty. Whether you're looking for a beach experience or simply want to enjoy nature, Melrose offers a variety of attractions that cater to every traveler's desire for adventure and relaxation.

  • Santa Fe Lake: Located 3 miles from Melrose, Santa Fe Lake offers a picturesque setting perfect for a romantic getaway or outdoor adventure. Enjoy its sandy beach, beautiful scenery, and a variety of recreational activities like swimming, fishing, and picnicking.
  • Gold Head Branch State Park: About 11 miles away, Gold Head Branch State Park is a haven for adventure seekers. With hiking trails, scenic views, and opportunities for camping, this park immerses you in nature's beauty while providing thrilling outdoor experiences.
  • Lake Como United Methodist Church: Located 15 miles from Melrose, this charming church is a cultural gem. Its historic architecture and serene atmosphere offer a glimpse into the local community's traditions and values, making it a peaceful stop for reflection.

Best time to go to Melrose

The best time to visit Melrose can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Melrose falls in July and August. August has average visitor numbers and mostly sunny weather. The coolest average temperature in Melrose falls in January, visitor numbers are average and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January55.8°F (13.2°C)Light RainMostly SunnyAverageSlightly Low
February60.1°F (15.6°C)Light RainMostly SunnyAverageAverage
March64.2°F (17.9°C)Light RainMostly SunnyAverageAverage
April70.2°F (21.2°C)Light RainMostly SunnySlightly HighAverage
May75.6°F (24.2°C)Light RainMostly SunnyAverageSlightly High
June80.1°F (26.7°C)Light RainMostly SunnyAverageAverage
July81.5°F (27.5°C)Light RainMostly SunnySlightly HighSlightly Low
August81.5°F (27.5°C)Light RainMostly SunnyAverageAverage
September78.6°F (25.9°C)Light RainMostly SunnySlightly HighSlightly High
October72.0°F (22.2°C)Light RainMostly SunnySlightly LowSlightly High
November63.9°F (17.7°C)Light RainMostly SunnySlightly LowAverage
December59.9°F (15.5°C)Light RainMostly SunnySlightly LowSlightly Low

The nearest major airports for your trip to Melrose

For your trip to Melrose, Florida, you have several airport options. Jacksonville International Airport (JAX) is about 58 miles away, with nearby hotels including the 4-star DoubleTree by Hilton Hotel Jacksonville Airport, located 0.3 miles from the airport. Gainesville Regional Airport (GNV) is much closer, at 14 miles away, offering convenient accommodations like the 4-star DoubleTree by Hilton Gainesville, just 8 miles from the airport. Lastly, Northeast Florida Regional Airport (UST) is 46 miles away, with options like the 4-star Casa Monica Resort & Spa, located 5 miles from the airport. Each hotel provides various transportation services for easy access to these airports.

Frequently asked questions

When is the best time to go to Melrose?
The most popular time to visit Melrose is during the late spring and summer months, particularly June. This period is characterized by pleasantly warm weather, with temperatures averaging around 65°F to 70°F, making it great for outdoor activities like hiking the scenic trails of the nearby Eildon Hills or exploring the historic Melrose Abbey.

During the peak season, from June to August, the town comes alive with visitors enjoying its charming streets, local shops, and vibrant community events. If you appreciate attentive service and a relaxed atmosphere, this bustling time offers plenty of opportunities to engage with locals and fellow travelers, all while experiencing the best of Melrose's offerings.

For those who enjoy cultural events, June often features various festivals and activities that celebrate local traditions, providing an immersive experience in the heart of the Scottish Borders. The long daylight hours allow for extended exploration, whether you're indulging in outdoor dining at a local café or taking leisurely strolls through the picturesque landscapes.

If you're looking for a more budget-friendly option, consider visiting in September. This month typically sees fewer crowds, allowing for a more tranquil experience while still enjoying pleasant weather. You can take advantage of slightly lower accommodation rates while exploring the beauty and history of Melrose without the hustle of peak tourist season.
Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Melrose hotel for you.
How can I save on a Melrose hotel booking with Expedia?
One Key™ - Expedia's free travel rewards program - gives you instant access to perks and Member Prices on Melrose hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings.

*OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Melrose hotel?
Prices for hotels in Melrose often vary, but you can find a great deal from $75 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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