Find hotels in Melrose, FL from $62

  • Upfront pricing

    Our total price for your stay includes taxes and fees
  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Melrose hotels

Drury Inn & Suites Gainesville

Drury Inn & Suites Gainesville
3.0 star property
Gainesville
9.6 out of 10, Exceptional, (1,453 reviews)
"Everything about our stay was perfect. The staff is friendly and I loved the breakfast. "
United States
Gregory
$104 nightly
The price is $117
May 21 - May 22
Total with taxes and fees
Drury Inn & Suites Gainesville

Hyatt Place Gainesville Downtown

Hyatt Place Gainesville Downtown
3.0 star property
Downtown Gainesville
9.2 out of 10, Wonderful, (1,168 reviews)
"My favorite place to stay in Gainesville when visiting my daughter! All the staff are wonderful, nice and helpful. Location is perfect and the beds are so comfy"
United States
Dina
$115 nightly
The price is $129
May 23 - May 24
Total with taxes and fees
Hyatt Place Gainesville Downtown

Country Inn & Suites by Radisson, Gainesville, FL

Country Inn & Suites by Radisson, Gainesville, FL
3.0 star property
Gainesville
9.2 out of 10, Wonderful, (1,813 reviews)
"We had the best stay here. Will stay here the next time we are in town! "
United States
Elisabeth
$88 nightly
The price is $99
Jun 8 - Jun 9
Total with taxes and fees
Country Inn & Suites by Radisson, Gainesville, FL

Comfort Suites Gainesville near University

Comfort Suites Gainesville near University
2.5 star property
Gainesville
9.2 out of 10, Wonderful, (1,348 reviews)
"Very nice and clean, good breakfast"
United States
Natalya
$89 nightly
The price is $100
May 24 - May 25
Total with taxes and fees
Comfort Suites Gainesville near University

Hotel Eleo at the University of Florida

Hotel Eleo at the University of Florida
3.0 star property
Gainesville
9.4 out of 10, Exceptional, (1,275 reviews)
"Clean room great staff"
United States
MaryAnn
$162 nightly
The price is $182
May 24 - May 25
Total with taxes and fees
Hotel Eleo at the University of Florida

Hotel Indigo Gainesville-Celebration Pointe by IHG

Hotel Indigo Gainesville-Celebration Pointe by IHG
3.5 star property
Gainesville
9.0 out of 10, Wonderful, (1,000 reviews)
"Excellent and convenient hotel in a good location."
United States
donnie
$111 nightly
The price is $125
May 24 - May 25
Total with taxes and fees
Hotel Indigo Gainesville-Celebration Pointe by IHG

Sleep Inn & Suites University/Shands

Sleep Inn & Suites University/Shands
2.5 star property
Gainesville
8.8 out of 10, Excellent, (1,184 reviews)
"We had a great stay! Breakfast was good and the staff were very nice. "
United States
Christina
$78 nightly
The price is $87
Jun 8 - Jun 9
Total with taxes and fees
Sleep Inn & Suites University/Shands

Best Western Gateway Grand

Best Western Gateway Grand
3.0 star property
Gainesville
8.6 out of 10, Excellent, (1,464 reviews)
"The staff was very helpful with checking and out and shuttle to the airport"
United States
Alesa
$93 nightly
The price is $104
May 20 - May 21
Total with taxes and fees
Best Western Gateway Grand

HOM Hotel Gainesville, SureStay Collection by Best Western

HOM Hotel Gainesville, SureStay Collection by Best Western
2.5 star property
Gainesville
8.6 out of 10, Excellent, (1,919 reviews)
"Clean rooms, good breakfast would stay here again "
United States
Seana
$77 nightly
The price is $87
May 20 - May 21
Total with taxes and fees
HOM Hotel Gainesville, SureStay Collection by Best Western

Comfort Inn University

Comfort Inn University
2.5 star property
Gainesville
8.4 out of 10, Very Good, (1,061 reviews)
"Clean and staff was amazing the breakfast was perfect"
United States
Christina
$85 nightly
The price is $96
May 24 - May 25
Total with taxes and fees
Comfort Inn University

DoubleTree by Hilton Gainesville

DoubleTree by Hilton Gainesville
4.0 star property
Gainesville
8.0 out of 10, Very Good, (1,015 reviews)
"Great stay "
United States
Sherri
$97 nightly
The price is $109
May 24 - May 25
Total with taxes and fees
DoubleTree by Hilton Gainesville

La Quinta by Wyndham Gainesville

La Quinta by Wyndham Gainesville
3.0 star property
Gainesville
9.0 out of 10, Wonderful, (1,223 reviews)
"The hotel was clean, complementary breakfast was better than most, bed was comfortable, and the room was spacious. We would definitely stay here again."
United States
MICHELLE
$102 nightly
The price is $114
May 17 - May 18
Total with taxes and fees
La Quinta by Wyndham Gainesville

Hilton University of Florida Conference Center Gainesville

Hilton University of Florida Conference Center Gainesville
3.5 star property
Gainesville
8.4 out of 10, Very Good, (1,018 reviews)
"A very good stay at a clean hotel."
United States
Kenneth
$114 nightly
The price is $128
May 20 - May 21
Total with taxes and fees
Hilton University of Florida Conference Center Gainesville

Red Roof Inn PLUS+ Gainesville

Red Roof Inn PLUS+ Gainesville
2.5 star property
Gainesville
7.4 out of 10, Good, (1,299 reviews)
"Always a solid goto for me and my service dog"
United States
Matthew
$64 nightly
The price is $72
Jun 1 - Jun 2
Total with taxes and fees
Red Roof Inn PLUS+ Gainesville

Super 8 by Wyndham Gainesville I-75 Hospital University Area

Super 8 by Wyndham Gainesville I-75 Hospital University Area
2.0 star property
Gainesville
7.6 out of 10, Good, (1,018 reviews)
"Clean room, welcoming staff, location great"
United States
Jon
$54 nightly
The price is $61
May 17 - May 18
Total with taxes and fees
Super 8 by Wyndham Gainesville I-75 Hospital University Area

Holiday Inn Gainesville - University Center by IHG

Holiday Inn Gainesville - University Center by IHG
3.0 star property
University Heights
8.0 out of 10, Very Good, (1,000 reviews)
"Great breakfast & clean rooms"
United States
Meenakshi
$110 nightly
The price is $124
May 24 - May 25
Total with taxes and fees
Holiday Inn Gainesville - University Center by IHG

Holiday Inn Express Starke by IHG

Holiday Inn Express Starke by IHG
2.5 star property
Starke
9.6 out of 10, Exceptional, (550 reviews)
"Facility was very clean and breakfast was very good. Would definitely stay again. "
United States
Sheila
$122 nightly
The price is $135
Jun 1 - Jun 2
Total with taxes and fees
Holiday Inn Express Starke by IHG

Sweetwater Branch Inn

Sweetwater Branch Inn
3.5 star property
Gainesville
9.6 out of 10, Exceptional, (1,000 reviews)
"Breakfast and total stay was perfect "
United States
Ricky
$115 nightly
The price is $130
May 24 - May 25
Total with taxes and fees
Sweetwater Branch Inn

SpringHill Suites by Marriott Gainesville

SpringHill Suites by Marriott Gainesville
3.0 star property
Gainesville
8.8 out of 10, Excellent, (1,000 reviews)
"Hotel was great, friendly staff. "
United States
AnaMaria
$93 nightly
The price is $104
May 18 - May 19
Total with taxes and fees
SpringHill Suites by Marriott Gainesville

Hilton Garden Inn Gainesville

Hilton Garden Inn Gainesville
3.0 star property
Gainesville
8.8 out of 10, Excellent, (1,000 reviews)
"Very nice place, adjacent to numerous shopping and dining options."
United States
Joel
$96 nightly
The price is $108
May 24 - May 25
Total with taxes and fees
Hilton Garden Inn Gainesville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Melrose

Nestled along Lake Santa Fe, this charming town offers peaceful kayaking and fishing at Melrose Bay Park. Art lovers can browse local galleries and studios, then enjoy fresh farm-to-table dining at the weekend farmers' market.

Photo by Matt Mateo
Open Photo by Matt Mateo

Top Melrose Hotel Reviews

More cheap stays in Melrose

Hotels in Melrose with star-rating

Find out more about Melrose

Top reasons to visit Melrose

  • Outdoor Adventures: Melrose is ideal for exploring beautiful lakes, national and state parks, and urban parks, perfect for nature enthusiasts.
  • Charming Atmosphere: The friendly vibe and inviting main streets make Melrose a great destination for romantic getaways or family fun.
  • Unique Experiences: Don't miss whale watching, which offers a memorable touch to your vacation in this quaint town.
  • Variety of Accommodations: Choose from cozy motels to inviting hotels, catering to diverse vacation needs.
  • Accessible Location: Just a short drive from Gainesville and Palatka, Melrose is conveniently located for easy exploration.

Find great hotels near Melrose

Discover a range of hotel accommodations in Melrose, Florida, perfect for your vacation needs. Whether you're seeking a pet-friendly stay, a comfortable spot for business travel, or an adventure-filled experience, Melrose offers a variety of options. From cozy motels to inviting hotels, you'll find the perfect room to make your visit enjoyable and memorable.

  • Hotel Eleo at the University of Florida: A 3.5-star hotel with an impressive guest rating of 9.4, Hotel Eleo at the University of Florida is a charming retreat located 18 miles from Melrose. This property stands out for its pet-friendly atmosphere, making it an excellent choice for travelers who wish to bring their furry companions along. With a variety of pet amenities, including a fee-waived service animal policy, guests can feel at home while enjoying the university's vibrant surroundings. The hotel offers a stylish blend of modern comfort and Southern hospitality, creating an inviting space for both relaxation and exploration.
  • Hyatt Place Gainesville Downtown: A 3-star hotel with a notable guest rating of 9.2, Hyatt Place Gainesville Downtown is situated 17 miles from Melrose and caters to families and business travelers alike. This property features a unique hot spring theme, with nearby access to natural hot springs for a rejuvenating experience. Amenities for children, such as free cribs and pool toys, ensure that families can enjoy their stay without compromising comfort. The hotel's modern design and welcoming atmosphere make it an ideal base for exploring the vibrant downtown area while enjoying quality time with loved ones.
  • Hampton Inn & Suites Gainesville-Downtown: A budget-friendly option with a guest rating of 8.6, Hampton Inn & Suites Gainesville-Downtown is located 17 miles from Melrose. This hotel is perfect for travelers seeking a pet-friendly environment while balancing business and leisure. It has a pet policy that accommodates various sizes, with fees waived for service animals. Guests will appreciate the comfortable rooms, complimentary breakfast, and convenient access to downtown, making it a practical choice for those looking to stay connected while enjoying the local attractions.

Where to stay in and around Melrose

Melrose, Florida, offers a charming escape with its friendly atmosphere and outdoor allure, perfect for romantic getaways or family adventures. Just a short drive from nearby cities like Gainesville and Palatka, you'll find local amenities and inviting main streets to explore. Enjoy scenic views and summer staycations that highlight the beauty of this hidden gem, making it an ideal destination for relaxation and discovery.

  • Earleton: Nestled just 3 miles from Melrose, Earleton is a charming city that offers a delightful outdoor experience, making it a popular choice for those seeking scenic views and romantic getaways. Visitors can explore its beautiful recreational areas, indulge in adventure activities, and even dive into underwater sports. The proximity to stunning lakes, rivers, and a national state park enhances its appeal, providing ample opportunities for nature lovers to immerse themselves in the great outdoors. The best time to visit is during the peak months of March, August, and November, when the weather is ideal for outdoor adventures.
  • Grandin: Located close to Melrose, Grandin is a quaint village known for its picturesque scenery and romantic atmosphere. Travelers flock here for its serene charm, with the local lakes serving as perfect spots for relaxation and reflection. The village provides a peaceful escape from the hustle and bustle, making it an ideal destination for couples and outdoor enthusiasts alike. Similar to Earleton, Grandin experiences peak visitor numbers in March, August, and November, making these months perfect for a visit to enjoy its natural beauty.
  • Keystone Heights: A mere 5 miles from Melrose, Keystone Heights is a unique city characterized by its island-like features. This vibrant locale is a haven for outdoor enthusiasts, offering various recreational areas and adventure activities, including underwater sports. Visitors are drawn to its breathtaking lakes, rivers, and the nearby national state park, which provide stunning backdrops for exploration and relaxation. Keystone Heights sees peak travel seasons in February to March and December, making it an excellent choice for tourists looking to connect with nature and enjoy a romantic getaway.

Things to do near Melrose

Melrose, Florida, is perfect for outdoor adventures and romantic getaways. Visitors can enjoy a range of activities, including exploring the beautiful recreational areas, indulging in educational experiences, and hitting the golf courses. While shopping opportunities abound, don't miss the chance for unique experiences like whale watching, which adds a memorable touch to your vacation in this charming town.

Shopping

In Melrose, enjoy local shops offering unique gifts and souvenirs. If you're up for a drive, visit the Gainesville Mall, about 15 miles away, which features a variety of national retailers and dining options for a more extensive shopping experience.

Recreation

Haile Plantation Golf and Country Club offers a luxurious golfing experience just 25 miles from Melrose, featuring pristine greens and upscale amenities. Similarly, Magnolia Point Golf and Country Club, located 29 miles away, provides an elegant atmosphere perfect for relaxation and recreation amidst beautiful landscapes.

Adventure

Explore the serene waters of Lake Santa Fe for kayaking and fishing, or hike the scenic trails at the nearby San Felasco Hammock Preserve State Park for a chance to spot local wildlife. For a thrilling experience, try horseback riding at local stables for a fun adventure.

Nightlife

Explore the vibrant nightlife in Melrose by visiting The Melrose Community Center for local events and gatherings. For a laid-back evening, check out the Melrose Pub, where you can enjoy a cold drink and mingle with friendly locals in a cozy atmosphere.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Melrose

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Melrose are July and December to January, where the prices are slightly lower. This is in comparison to May and September to October, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Melrose is Tuesday. The most expensive day to stay in Melrose is Saturday.
  • Find cheap hotels on Expedia: Utilize Expedia’s search tool to customize your travel preferences, such as your budget, desired location, and preferred hotel type. For instance, selecting the Eco-certified option will showcase sustainable and environmentally friendly hotels currently available. To find the best prices and deals, simply sort the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel stay in Melrose with your flights and activities through an Expedia package deal.

Find the best attractions near Melrose

Melrose, Florida, is perfect for outdoor enthusiasts and romantic getaways, offering stunning scenery and a variety of attractions. Visitors can explore beautiful lakes, venture into nearby national and state parks, or relax in urban parks. For those seeking a beach experience or vibrant outdoor activities, Melrose provides a delightful escape into nature, making it an ideal destination for travelers looking to enjoy the great outdoors.

  • Santa Fe Lake: Located 3 miles from Melrose, Santa Fe Lake offers a serene escape with its picturesque scenery and sandy beach vibes. It's perfect for a romantic day or a family outing, providing opportunities for swimming, picnicking, and enjoying nature's beauty.
  • Gold Head Branch State Park: Situated 11 miles away, this state park is a haven for adventure lovers. Explore its scenic trails, discover diverse wildlife, and enjoy outdoor activities like hiking, biking, and camping amidst lush landscapes.
  • Lake Como United Methodist Church: About 15 miles from Melrose, this church invites visitors to experience its rich cultural heritage. Attend a service or enjoy the community events that highlight the local traditions and values.

Best time to go to Melrose

The best time to visit Melrose is dependent on what kind of holiday you are seeking. July and August are its hottest month on average. At the time of August, visitor numbers are average and weather is mostly sunny. January is its coolest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January55.8°F (13.2°C)Light RainMostly SunnyAverageSlightly Low
February60.1°F (15.6°C)Light RainMostly SunnyAverageAverage
March64.2°F (17.9°C)Light RainMostly SunnyAverageAverage
April70.2°F (21.2°C)Light RainMostly SunnySlightly HighAverage
May75.6°F (24.2°C)Light RainMostly SunnyAverageSlightly High
June80.1°F (26.7°C)Light RainMostly SunnyAverageAverage
July81.5°F (27.5°C)Light RainMostly SunnySlightly HighSlightly Low
August81.5°F (27.5°C)Light RainMostly SunnyAverageAverage
September78.6°F (25.9°C)Light RainMostly SunnySlightly HighSlightly High
October72.0°F (22.2°C)Light RainMostly SunnySlightly LowSlightly High
November63.9°F (17.7°C)Light RainMostly SunnySlightly LowAverage
December59.9°F (15.5°C)Light RainMostly SunnySlightly LowSlightly Low

The nearest major airports for your trip to Melrose

Traveling to Melrose, Florida, is convenient with three major airports nearby. Jacksonville International Airport (JAX) is 58 miles away, with hotels like the DoubleTree by Hilton Hotel Jacksonville Airport, just 0.3 miles from the airport, and the Hyatt Regency Jacksonville, located 12 miles away. Daytona Beach International Airport (DAB), situated 70 miles from Melrose, offers nearby accommodations such as The Shores Resort & Spa and Daytona Grande Oceanfront Resort, both 4 miles away. Gainesville Regional Airport (GNV) is the closest at 14 miles, featuring hotels like DoubleTree by Hilton Gainesville, 8 miles away, and Hotel Eleo at the University of Florida, just 5 miles from the airport.

Why book with Expedia?

  • Flexible booking

    On Expedia, you can find plenty of hotels with flexible cancellation in Melrose using the “Fully refundable property” search filter. Just be sure to always double-check each hotel's cancellation policy before booking.

  • Book now and pay later

    With countless book now, pay later options, there's no need to wait till payday to grab a deal. Use the “Reserve now, pay later” search filter to view all properties available with this payment option in Melrose.

  • Hotel comparison

    Thanks to the handy “Compare properties” tool on Expedia, you can compare hotels in Melrose side by side with just a few clicks.

  • Member prices

    Join Expedia's loyalty program, One Key, for free and unlock Member Prices and rewards on select hotels worldwide. Simply log in when you search and look out for the blue savings label.

Frequently asked questions

What is the best area to stay in Melrose?
The best area to stay in Melrose is directly within the town center, particularly around the intersection of SR 21 and SR 26, as this is where you'll find the most convenient access to local amenities and the lake.

Melrose itself is a small, quiet town centered around Melrose Bay on Lake Santa Fe, one of Florida's largest and cleanest lakes. The main activity revolves around the lake, with opportunities for boating, fishing, and enjoying the water. The town center offers a few local eateries and shops, providing a pleasant base for a relaxed stay.

Couples looking for a tranquil getaway will find Melrose an excellent fit. The area provides a peaceful setting away from city noise, superb for enjoying nature and quality time together.
When is the best time to go to Melrose?
The best time to visit Melrose, Florida, is during the spring (March to May) and fall (September to November) when the weather is most pleasant.

During these seasons, you'll experience mild temperatures and lower humidity, making it ideal for enjoying outdoor activities like exploring the local lakes and nature trails. The spring brings blooming wildflowers, while the fall offers comfortable conditions for fishing, kayaking, or simply relaxing by the water.

Melrose is particularly appealing to those looking for a laid-back getaway, away from more crowded tourist destinations.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Melrose.
How can I save on a Melrose hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Melrose hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Melrose hotel?
Prices for hotels in Melrose often vary, but you can find a great deal from $62 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Explore a world of travel with Expedia