Title: O'Higgins Region Vacation Packages 2026 from $916 | Expedia.com [O'Higgins Region Travel Guide](https://expedia.com/OHiggins-Region.dx6236498)[O'Higgins Region Hotels](https://expedia.com/Destinations-In-OHiggins-Region.d6236498.Hotel-Destinations)[Vacation Rentals in O'Higgins Region](https://expedia.com/Destinations-In-OHiggins-Region.d6236498.Vacation-Rental-Destinations)[O'Higgins Region Flights](https://expedia.com/Destinations-In-OHiggins-Region.d6236498.Flight-Destinations)[Car Rentals in O'Higgins Region](https://expedia.com/Destinations-In-OHiggins-Region.d6236498.Car-Rental-Destinations) ![](https://images.trvl-media.com/place/6236498/bc4139c5-8c17-4458-944b-d1b94ea3e5d9.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # O'Higgins Region Vacations & Trips from $916 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ### Your O'Higgins Region Vacation See and do more with a vacation package to O'Higgins Region. Whether you're going for the culture, festivals, history, or something else, our package deals make travel planning simple. A trip to O'Higgins Region wouldn't be complete without exploring some of its best cities, starting with [Santa Cruz](https://www.expedia.com/Santa-Cruz.d6047957.Destination-Travel-Guides). A couple of the top attractions here include Lapostolle Clos Apalta Winery and Casino Colchagua. [Rancagua](https://www.expedia.com/Rancagua.d6085078.Destination-Travel-Guides) should also be on the itineraries of all O'Higgins Region travelers. Visitors to this exciting destination enjoy Parque Safari Chile and Reserva Nacional Rio Cipreses. Expedia has hotels, flights and whatever else you need to help you curate your own tailored O'Higgins Region vacation today. ## Top destinations in O'Higgins Region ![Meanders at the delta river Rapel in the town of La Boca. An amazing view of the bends of the river looking for an exit to the Pacific Ocean in between the valleys, hills and forests an awe landscape](https://images.trvl-media.com/place/3000458771/e23e3056-ae84-487e-a922-dcb61859fa71.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Navidad [](https://expedia.com/Navidad.d3000458771.Destination-Travel-Guides) ![Rows of vineyards, Santa Cruz, Chile](https://images.trvl-media.com/place/6047957/e58d3014-ef10-4c60-9e03-08890e2f5494.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Santa Cruz [](https://expedia.com/Santa-Cruz.d6047957.Destination-Travel-Guides) ![Adobe](https://images.trvl-media.com/place/6130903/25bf5ef3-5202-48c4-b6da-460bae0cd16f.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Pichilemu [](https://expedia.com/Pichilemu.d6130903.Destination-Travel-Guides) ![Aerial view of the Church of San Vicente de Ferrer de Los Dominicos in Santiago de Chile and magnificent City](https://images.trvl-media.com/place/6338195/45308196-8702-4fb9-ba75-bf916d967c67.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### San Vicente [](https://expedia.com/San-Vicente.d6338195.Destination-Travel-Guides) ![paisaje campestre chile](https://images.trvl-media.com/place/6085078/5d727250-23a7-47a2-8bd2-11520d030e40.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Rancagua [](https://expedia.com/Rancagua.d6085078.Destination-Travel-Guides) ![Beautiful Vineyard path](https://images.trvl-media.com/place/6053655/dd8cbc89-fd67-40b1-948c-2948575ec8fe.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### San Fernando [](https://expedia.com/San-Fernando.d6053655.Destination-Travel-Guides) ## The Latest O'Higgins Region Vacation Packages Price found within the past 48 hours. Click for updated prices. ![Matildas Hotel Boutique](https://images.trvl-media.com/lodging/10000000/10000000/9995600/9995554/2c23ac23_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Matildas Hotel Boutique Downtown Santiago $916 per person May 10 - May 16 found 24 hours ago Roundtrip non-stop flight included Miami (MIA) to Santiago (SCL) 9.4/10 Exceptional! (280 reviews) The hotel is so pretty that it is a gem In the old centro of Santiago. Nice breakfast and very nice staff specially Fernanda and Macarena. Reviewed on Mar 13, 2026 ![Noi Vitacura](https://images.trvl-media.com/lodging/5000000/4250000/4248400/4248306/1db5a2ba_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Noi Vitacura Vitacura $1,061 per person May 10 - May 16 found 24 hours ago Roundtrip non-stop flight included Miami (MIA) to Santiago (SCL) 8.6/10 Excellent! (567 reviews) Clean room, nice rooftop restaurant and very helpful, friendly staff! Thank you, Noi Staff! Ann from SF Reviewed on Feb 20, 2026 ![Mandarin Oriental, Santiago](https://images.trvl-media.com/lodging/1000000/20000/15200/15107/b011d513_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Mandarin Oriental, Santiago Las Condes $2,362 per person May 2 - May 9 found 10 hours ago Roundtrip non-stop flight included Miami (MIA) to Santiago (SCL) 9.2/10 Wonderful! (982 reviews) Best hotel experience to date. Room was gorgeous. Staff was super friendly and welcoming. Spa was relaxing and perfectly thought out. Reviewed on Mar 16, 2026 ![Hotel Magnolia](https://images.trvl-media.com/lodging/16000000/15550000/15544900/15544814/621fc26e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Magnolia Downtown Santiago $1,439 per person May 7 - May 14 found 1 day ago Roundtrip non-stop flight included Santo Domingo (SDQ) to Santiago (SCL) 9.6/10 Exceptional! (329 reviews) We loved the location of the hotel and the reception and housekeeping staff were so pleasant. The restaurant staff were a little slow to take orders and bring drinks. Room was so spacious and clean . Reviewed on Mar 7, 2026 ## Find the Best O'Higgins Region Vacation Packages ## OHiggins Region Essential Information | Language | Spanish | | --------------- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Currency | Chilean pesos | | Local Welcome | ¡Hola! | | Local Goodbye | Adiós | | Closest Airport | Arturo Merino Benitez Airport (SCL) | | Top Sights | [Punta de Lobos Beach](https://www.expedia.com/Punta-De-Lobos-Beach-OHiggins-Region.d553248621593240891.Vacation-Attraction), [Lobos Point](https://www.expedia.com/Lobos-Point-Pichilemu.d553248621563217619.Vacation-Attraction) and [Pichilemu Beach](https://www.expedia.com/Pichilemu-Beach-OHiggins-Region.d6099460.Vacation-Attraction) | ## O'Higgins Region Hotel Deals ![Vik Chile](https://images.trvl-media.com/lodging/9000000/8730000/8726600/8726594/a803556f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Vik Chile Valle de Millahue San Vicente O'Higgins $629 nightly $629 total Apr 13 - Apr 14 9.2/10 Wonderful! (179 reviews) Espectacular!!! Estás en el viñedo, te atienden con mucha familiaridad, todos muy joviales y amables. Las habitaciones son espectaculares; la comida es deliciosa Reviewed on Mar 5, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F13%2F2026&endDate=4%2F14%2F2026&selected=8726594&PinnedHotelID=8726594&HadPinnedHotel=true®ionId=6236498) ![Hotel Terrado Rancagua](https://images.trvl-media.com/lodging/89000000/88400000/88398500/88398434/a0f87ef2_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Terrado Rancagua 290 Avenida Alberto Einstein Rancagua Racagua Fully refundableReserve now, pay when you stay $81 nightly $81 total Mar 22 - Mar 23 9/10 Wonderful! (57 reviews) Large well furnished room. Great breakfast. Free parking in the underground carpark which serves the hotel and shopping mall. Reviewed on Feb 15, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F22%2F2026&endDate=3%2F23%2F2026&selected=88398434&PinnedHotelID=88398434&HadPinnedHotel=true®ionId=6236498) ![Santa Cruz Plaza](https://images.trvl-media.com/lodging/2000000/1410000/1406700/1406642/3fe1c8d9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Santa Cruz Plaza Plaza De Armas 286 Santa Cruz O'Higgins Fully refundableReserve now, pay when you stay $126 nightly $126 total Apr 5 - Apr 6 8.8/10 Excellent! (348 reviews) Mostly clean room, wonderful staff Reviewed on Mar 2, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=1406642&PinnedHotelID=1406642&HadPinnedHotel=true®ionId=6236498) [See all 258 properties in O'Higgins Region](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=3%2F21%2F2026&endDate=3%2F22%2F2026®ionId=6236498) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Kid Friendly Vacations [](https://expedia.com/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Kid_Friendly%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.com/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.com/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.com/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.com/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ![Gay Friendly Vacations](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ Friendly Vacations [](https://expedia.com/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ_Friendly%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2017/07/05/170615_Adventure_1320_2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Adventure Vacations [](https://expedia.com/lp/theme-vacations/adventure-vacations?rfrr=editorial.Adventure_Vacations.click) ![Vacations in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.com/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/honeymoon_hawaii.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Honeymoon Vacations [](https://expedia.com/lp/theme-vacations/honeymoon-vacations?rfrr=editorial.Honeymoon_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/Mountain-vacations.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Mountain Vacations [](https://expedia.com/lp/theme-vacations/mountain-vacations?rfrr=editorial.Mountain_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/fishing-vacations-2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Fishing Vacations [](https://expedia.com/lp/theme-vacations/fishing-vacations?rfrr=editorial.Fishing_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2019/05/16/Hyatt%20Zilara%20Cancun%20-%20All%20Inclusive%20-%20Adults%20Only.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Adults Only Vacations [](https://expedia.com/lp/theme-vacations/adults-only-vacations?rfrr=editorial.Adults_Only%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/waterpark-vacations.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Waterpark Vacations [](https://expedia.com/lp/theme-vacations/waterpark-vacations?rfrr=editorial.Waterpark_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/Caribean_scuba_diving.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Scuba Diving Vacations [](https://expedia.com/lp/theme-vacations/scuba-diving-vacations?rfrr=editorial.Scuba_Diving%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/aruba_yoga.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Yoga Vacations [](https://expedia.com/lp/theme-vacations/yoga-vacations?rfrr=editorial.Yoga_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2023/04/04/EPS-RBC-SummerBeachVacations-AdobeStock_206356322.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Cheap Vacations [](https://expedia.com/lp/theme-vacations/cheap-vacations?rfrr=editorial.Cheap_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/06/26/1175883311.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Solo Vacations [](https://expedia.com/lp/b/vacations/solo-vacations?rfrr=editorial.Solo_Vacations.click) ### Discover the most popular places to visit in O'Higgins Region #### Lapostolle Clos Apalta Winery You can enjoy a tasting or tour at Lapostolle Clos Apalta Winery during your travels to Santa Cruz. While in this relaxing area, you can savor the wineries and restaurants. [](https://expedia.com/Lapostolle-Clos-Apalta-Winery-Santa-Cruz.d553248621532463283.Vacation-Attraction) #### Monticello Grand Casino and Convention Center Why not try your luck with a visit to Monticello Grand Casino and Convention Center during your visit to Mostazal? Make some time to visit the casinos while you're in the area. [](https://expedia.com/Monticello-Grand-Casino-And-Convention-Center-Mostazal.d6237441.Vacation-Attraction) #### Colchagua Valley Wine Route You can take time to visit Colchagua Valley Wine Route during your travels to Lolol. You can enjoy the wineries while in the area. [](https://expedia.com/Colchagua-Valley-Wine-Route-Lolol.d553248621532463279.Vacation-Attraction) ### What to do in O'Higgins Region ![Make Your Own Wine & Guided Vineyard Tour ](https://mediaim.expedia.com/localexpert/46200977/2edfdc20-7979-4beb-b97e-2ba00246939c.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Make Your Own Wine & Guided Vineyard Tour $46 per adult [](https://expedia.com/things-to-do/make-your-own-wine-guided-vineyard-tour.a46200977.activity-details) ![The Regenerative Farm and Sommelier Wine Tour](https://mediaim.expedia.com/localexpert/48697023/c2069796-47a5-497d-aecf-9138bd501e92.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### The Regenerative Farm and Sommelier Wine Tour $140 per adult [](https://expedia.com/things-to-do/the-regenerative-farm-and-sommelier-wine-tour.a48697023.activity-details) ![From Santiago to the Andes: 4x4, horseback riding, waterfall visit and barbecue](https://mediaim.expedia.com/localexpert/46739151/182f025d-9d04-4dc4-9ce7-3d330e20dcf0.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### From Santiago to the Andes: 4x4, horseback riding, waterfall visit and barbecue $300 per adult [](https://expedia.com/things-to-do/from-santiago-to-the-andes-4x4.a46739151.activity-details) [See all activities in O'Higgins Region](https://expedia.com/things-to-do/search?rid=6236498) Explore a world of travel with Expedia ## Other vacations you might like - Top cities in O'Higgins Region - Vacations and getaways similar to O'Higgins Region - Best vacation destinations by month - [Pichilemu Vacations ](https://expedia.com/Pichilemu.d6130903.Destination-Travel-Guides) - [San Vicente Vacations ](https://expedia.com/San-Vicente.d6338195.Destination-Travel-Guides) - [Santa Cruz Vacations ](https://expedia.com/Santa-Cruz.d6047957.Destination-Travel-Guides) - [Rancagua Vacations ](https://expedia.com/Rancagua.d6085078.Destination-Travel-Guides) - [Matanzas Vacations ](https://expedia.com/Matanzas.d3000006349.Destination-Travel-Guides) - [San Fernando Vacations ](https://expedia.com/San-Fernando.d6053655.Destination-Travel-Guides) - [Marchihue Vacations ](https://expedia.com/Marchihue.d6176398.Destination-Travel-Guides) - [Mostazal Vacations ](https://expedia.com/Mostazal.d6340588.Destination-Travel-Guides) - [Pichidegua Vacations ](https://expedia.com/Pichidegua.d6360683.Destination-Travel-Guides) - [Santiago Metropolitan Region Vacations ](https://expedia.com/Santiago-Metropolitan-Region.d6236511.Destination-Travel-Guides) - [Atacama Region Vacations ](https://expedia.com/Atacama-Region.d6236563.Destination-Travel-Guides) - [Valparaíso Vacations ](https://expedia.com/Valparaiso.d553248635997965347.Destination-Travel-Guides) - [Antofagasta Region Vacations ](https://expedia.com/Antofagasta-Region.d6236581.Destination-Travel-Guides) - [Magallanes y Antartica Chilena Vacations ](https://expedia.com/Magallanes-Y-Antartica-Chilena.d6236290.Destination-Travel-Guides) - [Los Lagos Region Vacations ](https://expedia.com/Los-Lagos-Region.d6236446.Destination-Travel-Guides) - [Araucanía Region Vacations ](https://expedia.com/Araucania-Region.d6236462.Destination-Travel-Guides) - [Biobío Vacations ](https://expedia.com/Biobio.d553248635997965342.Destination-Travel-Guides) - [Aysén del General Carlos Ibáñez del Campo Region Vacations ](https://expedia.com/Aysen-Del-General-Carlos-Ibanez-Del-Campo-Region.d6236429.Destination-Travel-Guides) - [Maule Region Vacations ](https://expedia.com/Maule-Region.d6236487.Destination-Travel-Guides) - [January Vacations and Deals ](https://www.expedia.com/lp/b/where-to-go/vacations-january) - [February Vacations and Deals ](https://www.expedia.com/lp/b/where-to-go/vacations-february) - [March Vacations and Deals ](https://www.expedia.com/lp/b/where-to-go/vacations-march) - [April Vacations and Deals ](https://www.expedia.com/lp/b/where-to-go/vacations-april) - [May Vacations and Deals ](https://www.expedia.com/lp/b/where-to-go/vacations-may) - [June Vacations and Deals ](https://www.expedia.com/lp/b/where-to-go/vacations-june) - [July Vacations and Deals ](https://www.expedia.com/lp/b/where-to-go/vacations-july) - [August Vacations and Deals ](https://www.expedia.com/lp/b/where-to-go/vacations-august) - [September Vacations and Deals ](https://www.expedia.com/lp/b/where-to-go/vacations-september) - [October Vacations and Deals ](https://www.expedia.com/lp/b/where-to-go/vacations-october) - [November Vacations and Deals ](https://www.expedia.com/lp/b/where-to-go/vacations-november) - [December Vacations and Deals ](https://www.expedia.com/lp/b/where-to-go/vacations-december) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app