Otay Mesa Vacations

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The Latest Otay Mesa Vacation Packages

Price found within the past 48 hours. Click for updated prices.
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
Downtown San Diego
Save 100% on your flight
per person
Jun 28 - Jul 2
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
8.2/10 Very Good! (1,328 reviews)
Excellent location, great staff. Wireless internet could be better.

Reviewed on May 16, 2024

Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
Save 100% on your flight
per person
Jun 28 - Jul 2
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
8.4/10 Very Good! (1,816 reviews)
My stay at paradise point was great! Customer service was excellent and food and drinks at barefoot were on point! Thanks!

Reviewed on May 14, 2024

Hyatt Vacation Club at The Welk, San Diego Area

Hyatt Vacation Club at The Welk, San Diego Area

3.5 out of 5
Lawrence Welk Resort Village
Save 100% on your flight
per person
Jun 28 - Jul 2
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
7.8/10 Good! (1,002 reviews)
We loved it here! It was so nice and quiet! Such a great staycation! So Family friendly and so much to do. There was a kitchen which was so useful and they were stocked with pots/pans/playes/cups/utensils and even grill amenities. It has a toaster, microwave, fridge, and coffee maker. Also has a little closet in the hallway with a broom/vacuum/iron/ironboard. The bathroom was pretty big with good water pressure and stocked with shampoo/conditioner/bodywash. Would definitely recommend! And would definitely stay again I wish check in time was earlier and check out was a little later to enjoy more but we did love the two pools and splash pad. So fun for the kids and us adults!

Reviewed on May 16, 2024

The Wayfarer San Diego

The Wayfarer San Diego

4 out of 5
Mission Beach
Save 100% on your flight
per person
Aug 1 - Aug 4
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
9/10 Wonderful! (1,057 reviews)
The hotel has been nicely refurbished and the staff is super nice and helpful. They also have their own onsite cafe. It is located in an older area that is outdated and in dire need of road repair. There is also a significant homeless presence. The property is private and secured though and conveniently located right on the beachfront.

Reviewed on May 17, 2024

Winners Circle Resort by VRI Americas

Winners Circle Resort by VRI Americas

3.5 out of 5
Save 100% on your flight
per person
Jul 22 - Jul 26
Roundtrip flight included
Seattle (SEA) to San Diego (SAN)
8.8/10 Excellent! (912 reviews)
I had a great stay and would book here again!

Reviewed on May 9, 2024

Where to stay in Otay Mesa

Find the best Otay Mesa areas and neighborhoods for the activities you enjoy most. Learn more about Otay Mesa
US Grant Hotel

Downtown San Diego

2 out of top 10 points of interest in this area
4.5/5(8,497 area reviews)

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Find hotel + flight trips in Downtown San Diego

Otay Mesa Hotel Deals

Wyndham San Diego Bayside
Wyndham San Diego Bayside
4 out of 5
1355 N Harbor Drive, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is $161 per night from May 28 to May 29
$161
$181 total
includes taxes & fees
May 28 - May 29
8/10 Very Good! (5,903 reviews)
Close to so many activities
"I like the fact that the hotel is close to harbor and so many activities!"

Reviewed on May 16, 2024

Wyndham San Diego Bayside
Wyndham Garden San Diego Near SeaWorld
Wyndham Garden San Diego Near SeaWorld
3 out of 5
3737 Sports Arena Blvd, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is $123 per night from May 28 to May 29
$123
$138 total
includes taxes & fees
May 28 - May 29
7/10 Good! (2,638 reviews)
"It was clean and quiet! A little over priced for the area!"

Reviewed on May 17, 2024

Wyndham Garden San Diego Near SeaWorld
Best Western Seven Seas
Best Western Seven Seas
3 out of 5
411 Hotel Circle South, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is $94 per night from May 19 to May 20
$94
$105 total
includes taxes & fees
May 19 - May 20
7.4/10 Good! (2,468 reviews)
"Morning Restaurant staff is the best!"

Reviewed on May 15, 2024

Best Western Seven Seas
See all 4,438 properties in Otay Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Explore other types of vacation packages

All Inclusive Vacations

All Inclusive Vacations

Beach Vacations

Beach Vacations

Kid Friendly Vacations

Kid Friendly Vacations

Frequently asked questions

How much does an Otay Mesa vacation package cost?
Starting from as low as $396, a vacation package is your ticket to cheaper travel. Create your own Otay Mesa escape by choosing from our wide range of hotels, airfares and rental cars.
How do I get a cheap travel package to Otay Mesa?
Our Otay Mesa vacation packages mean plenty of savings for the savvy wanderer. For the best deal, simply bundle your hotel, flights and extras (such as activities) into a neat and tidy package. But impressive bargains are only the start of your next amazing adventure. When you book with Expedia, you’ll have more than 550 air carriers and 1,000,000 hotel options all over the world to pick from. No matter your budget or style, there’s a package that’s perfect for you.
Where should I stay in Otay Mesa?
A getaway to Otay Mesa wouldn’t be complete without paying a visit to North Island Credit Union Amphitheatre, Aquatica and White Water Canyon. Spend your evenings close to these tourist attractions and make sightseeing simple.
What are the top hotels in Otay Mesa?
Book a stay at Holiday Inn Express Hotel & Suites San Diego Otay Mesa, an IHG Hotel. It’s one of this neighborhood’s most sought-after hotels. Another reputable option in Otay Mesa is Quality Suites San Diego Otay Mesa.
How far in advance should I book my Otay Mesa vacation?
Your best bet is to book early. Air carriers typically release flights around a year prior to departure, and this is an ideal opportunity to score some rock-bottom prices. Boss just told you to take your vacation time next month? That’s alright! Expedia are never short on fantastic deals to send you on the getaway of your dreams, at a price you can afford.
What does an Expedia Otay Mesa travel package include?
It comes down to what you want. If you’re traveling alone, you might decide to bundle flights and hotels. Bringing the entire family to Otay Mesa? A travel package that includes rental cars, flights and hotels might be a better fit. Expedia gives you the flexibility and freedom to tailor-make your travel package.
What should I know before booking an Otay Mesa travel package?
When you book your flights, hotels and car rentals together, you’ll land terrific discounts. Whether you’re organizing an island getaway in a villa or prefer to stay in a cozy apartment in the city, Expedia can help make it happen.
Can I choose my airline with an Otay Mesa Expedia vacation package?
You can, and with over 550 airlines to select from worldwide, you have loads of choice. Look through the available options and find out which airline best suits your needs and budget.
If I'm not able to travel, can I cancel my Otay Mesa vacation package?
Don’t worry if you’re rethinking your Otay Mesa vacation package — it’s possible to change or amend your booking. And if you’ve booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur fees from your hotel, airline or car rental company. We get that life can sometimes throw a spanner in the works, so make your way to our Customer Service Portal if that happens. When you’re ready to make changes, we’re ready to help.

Discover the most popular places to visit in Otay Mesa

Image for San Diego Zoo

San Diego Zoo

4.5/5(3,565 reviews)

See nature up-close and personal at one of the country’s largest and most educational zoos.

San Diego Zoo
Image for SeaWorld

SeaWorld

4.5/5(2,421 reviews)

Animal interaction, entertaining rides and informative exhibits are all on offer at this family favorite destination. 

SeaWorld
Image for Mission Bay

Mission Bay

4.5/5(2,386 reviews)

Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.

Mission Bay

Things to do

Image for Tijuana & Rosarito tour/the best tacos el yaqui

Tijuana & Rosarito tour/the best tacos el yaqui

$60
Per adult
Tijuana & Rosarito tour/the best tacos el yaqui
Image for Bufadora / La guerrerense seafood / four four vineyards

Bufadora / La guerrerense seafood / four four vineyards

$90
Per adult
Bufadora / La guerrerense seafood / four four vineyards
Image for Tijuana: Guided City Tour with Local Food and Beer Tasting

Tijuana: Guided City Tour with Local Food and Beer Tasting

$114
Per adult
Tijuana: Guided City Tour with Local Food and Beer Tasting
See all activities in San Diego

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.