Punta Paitilla Vacations from $665

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Your Punta Paitilla Vacation

The easiest way to experience this exciting city is with a tailor-made Punta Paitilla vacation package. Base yourself in the neighborhood of Marbella, which is good for cafes, walking and dining or go someplace else — our package deals are all about you. Every trip to Punta Paitilla needs a well-planned itinerary. Fill yours with attractions like Miraflores Locks, Bridge of the Americas and Metropolitan Cathedral of Panama. Expedia will help you escape your daily routine. Tailor your vacation to Punta Paitilla to suit your travel style, whatever that may be.

The Latest Punta Paitilla Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
Save 100% on your flight
Price was $1,148, price is now $665 per person
$665
per person
May 4 - May 11
found 23 hours ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
9.8/10 Exceptional! (60 reviews)
We stayed one night and it exceeded our expectations. The owners were incredibly friendly and easy to contact, making us feel right at home. Everything was spotless, and the atmosphere was warm and inviting. The homemade breakfast was a highlight—absolutely delicious and full of flavor. We will stay again longer next time.

Reviewed on Jan 22, 2026

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $1,980, price is now $1,196 per person
$1,196
per person
Apr 29 - May 5
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9/10 Wonderful! (1,002 reviews)
Room was amazing, beautiful hotel in the center of town. Service also very good and attentive. Amazing breakfast.

Reviewed on Feb 24, 2026

Yoo by Wynwood House

Yoo by Wynwood House

4 out of 5
Calidonia
Price was $1,764, price is now $1,225 per person
$1,225
per person
Apr 29 - May 5
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9.2/10 Wonderful! (5 reviews)
Unfortunately the name of the property was not Yoo by Wynwood. It is P. H. Yoo Panama & Arts Tower. This detail that was incorrect cost us time, money and stress at the beginning of our trip. We weren't able to get in touch with anyone at the property or at expedia and we ended up having to cross reference google photos to figure out the correct name and address of the location. This took us about an hour to do in a Country that we had never been to. We are very displeased with Expedia about this. We still have not been contacted by anyone.

Reviewed on Jul 26, 2025

Playa Caracol

Playa Caracol

3.5 out of 5
Save 100% on your flight
Price was $1,446, price is now $1,039 per person
$1,039
per person
May 4 - May 11
found 23 hours ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
8/10 Very Good! (5 reviews)

Where to stay in Punta Paitilla

Find the best Punta Paitilla areas and neighborhoods for the activities you enjoy most. Learn more about Punta Paitilla
View of the Panama City Old Town

Casco Viejo

4.5/5(178 area reviews)

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Find hotels in Casco Viejo

Punta Paitilla Hotel Deals

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
Fully refundableReserve now, pay when you stay
$166 nightly
The price is $183 total per night from Mar 1 to Mar 2
$183 total
Mar 1 - Mar 2
Total with taxes and fees
9/10 Wonderful! (1,052 reviews)
Habitacion cómoda, silenciosa y buen trato del personal

Reviewed on Feb 24, 2026

Las Americas Golden Tower Panama
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Avenida Balboa Con Multicentro Panama City Panama
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $128 total per night from Feb 26 to Feb 27
$128 total
Feb 26 - Feb 27
Total with taxes and fees
8.6/10 Excellent! (1,571 reviews)
Great

Reviewed on Feb 23, 2026

Decapolis Hotel Panama City
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

3.5 out of 5
Italy Avenue, Punta Paitilla Panama City Panama
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $119 total per night from Mar 26 to Mar 27
$119 total
Mar 26 - Mar 27
Total with taxes and fees
9.4/10 Exceptional! (2,153 reviews)
Large clean room, available early check-in for fee includes breakfast, very large breakfast/brunch and lovely seating area, bicycles for rent, good location

Reviewed on Feb 22, 2026

Plaza Paitilla Inn Hotel
See all 1,549 properties in Punta Paitilla
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Punta Paitilla

Rainy day in Panama City but the charm of this city never ends. A beautiful rainbow over the city invites us to spend a bright day in paradise. #LifeAtExpedia

Multiplaza Pacific Mall

During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Multiplaza Pacific Mall
Panama City night skyline

Avenida Balboa

You can find the perfect gifts to bring home at Avenida Balboa during your trip to Panama City. While you're in the area, wander around the natural setting.

Avenida Balboa
Causeway, Amador, Panama

Amador Causeway

You can learn about the history of Ancon with a stop at Amador Causeway. Stroll along the seaside or visit the shops in this vibrant area.

Amador Causeway

Things to do

From Panama City: Monkey Islands Tour on Gatun Lake

From Panama City: Monkey Islands Tour on Gatun Lake

$60
per adult
88% of travellers recommend
From Panama City: Monkey Islands Tour on Gatun Lake
Panama City: Zip Line Experience Over The City & a Cocktail

Panama City: Zip Line Experience Over The City

$40
per adult
92% of travellers recommend
Panama City: Zip Line Experience Over The City
Panama City Visit an Indian town Embera and waterfall with lunch

Panama City Visit an Indian town Embera and waterfall with lunch

$49
per adult
100% of travellers recommend
Panama City Visit an Indian town Embera and waterfall with lunch
See all activities in Panama City
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.