Punta Paitilla Vacation Packages 2026 from $921

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Your Punta Paitilla Vacation

The easiest way to experience this exciting city is with a tailor-made Punta Paitilla vacation package. Base yourself in the neighborhood of Marbella, which is good for cafes, walking and dining or go someplace else — our package deals are all about you. Every trip to Punta Paitilla needs a well-planned itinerary. Fill yours with attractions like Miraflores Locks, Bridge of the Americas and Metropolitan Cathedral of Panama. Expedia will help you escape your daily routine. Tailor your vacation to Punta Paitilla to suit your travel style, whatever that may be.

The Latest Punta Paitilla Vacation Packages

Price found within the past 48 hours. Click for updated prices.

Decapolis Hotel Panama City

San Francisco

$921

per person

Nov 18 - Nov 24

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

8.6/10 Excellent! (1,716 reviews)

Se nota mucho el deterioro y un sucio en los pacios.

Reviewed on Sep 3, 2026

Central Hotel Panama Casco Viejo

Casco Viejo

Save 100% on your flight

$1,095

per person

Nov 5 - Nov 10

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

9.2/10 Wonderful! (1,001 reviews)

Beautiful historic hotel we stayed there for 5 nights with a group of 33 people celebrating my brother’s 50 th birthday. very central, you can walk to go shopping or eating and dining at the roof top restaurants in the hotel or around Casco. The cocktails at the bar delicious and the breakfast was great variety, food was fresh. I’d rate the hotel Uber from there quick and cheap…….,10/10 great experience. The staff was also nice and very accommodating.

Reviewed on Sep 2, 2026

Megapolis Hotel Panamá

San Francisco

Save 100% on your flight

$1,145

per person

Oct 6 - Oct 11

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

8.4/10 Very Good! (1,692 reviews)

Nice clean room bed sheets was white an clean. Staff was friendly, breakfast was awesome

Reviewed on Sep 3, 2026

Casa Mallet by Wynwood House

Casco Viejo

Save 100% on your flight

$1,485

per person

Nov 12 - Nov 18

found 1 day ago

Roundtrip flight included

Georgetown (GEO) to Panama City (PTY)

9.8/10 Exceptional! (29 reviews)

Nice apartment ! Clean and great location

Reviewed on Aug 13, 2026

Las Americas Golden Tower Panama

San Francisco

$1,048

per person

Nov 18 - Nov 24

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

9/10 Wonderful! (1,103 reviews)

The breakfast was great and the rooms were comfortable

Reviewed on Sep 3, 2026

Where to stay in Punta Paitilla

Find the best Punta Paitilla areas and neighborhoods for the activities you enjoy most. Learn more about Punta Paitilla

A waterfront cityscape with historic buildings and a prominent clock tower.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

A cityscape with modern skyscrapers, including a distinctive twisting tower.

Bella Vista

1 out of top 10 points of interest in this area

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station.

A city skyline with modern high-rise buildings and a river in the foreground.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

A bridge over a body of water with several boats.

San Francisco

1 out of top 10 points of interest in this area

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

A coastal city skyline with high-rise buildings, palm trees, and a clear sky.

Calidonia

2 out of top 10 points of interest in this area

You might enjoy the shopping while in Calidonia. Via Espana is a notable sight, and you can get around town at Lotería Station or Santo Tomás Station to see more of the city.

Punta Paitilla Hotel Deals

Megapolis Hotel Panamá

Avenida Balboa Panama City

Fully refundableReserve now, pay when you stay

$132 nightly

$132 total

Sep 9 - Sep 10

Total with taxes and fees

8.4/10 Very Good! (1,700 reviews)

"Nice clean room bed sheets was white an clean. Staff was friendly, breakfast was awesome"

Reviewed on Sep 3, 2026

Las Americas Golden Tower Panama

Av. Balboa con Calle 53 Panama City Panama

Fully refundableReserve now, pay when you stay

$147 nightly

$161 total

Sep 6 - Sep 7

Total with taxes and fees

9/10 Wonderful! (1,099 reviews)

"The breakfast was great and the rooms were comfortable"

Reviewed on Sep 3, 2026

Decapolis Hotel Panama City

Avenida Balboa Con Multicentro Panama City Panama

Fully refundableReserve now, pay when you stay

$63 nightly

$70 total

Oct 3 - Oct 4

Total with taxes and fees

8.6/10 Excellent! (1,709 reviews)

"Se nota mucho el deterioro y un sucio en los pacios."

Reviewed on Sep 3, 2026

See all 1,819 properties in Punta Paitilla

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.