Punta Paitilla Vacations from $666

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Your Punta Paitilla Vacation

The easiest way to experience this exciting city is with a tailor-made Punta Paitilla vacation package. Base yourself in the neighborhood of Marbella, which is good for cafes, walking and dining or go someplace else — our package deals are all about you. Every trip to Punta Paitilla needs a well-planned itinerary. Fill yours with attractions like Miraflores Locks, Bridge of the Americas and Metropolitan Cathedral of Panama. Expedia will help you escape your daily routine. Tailor your vacation to Punta Paitilla to suit your travel style, whatever that may be.

The Latest Punta Paitilla Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
Save 100% on your flight
Price was $1,165, price is now $666 per person
$666
per person
May 4 - May 11
found 1 day ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
9.8/10 Exceptional! (64 reviews)
We stayed one night and it exceeded our expectations. The owners were incredibly friendly and easy to contact, making us feel right at home. Everything was spotless, and the atmosphere was warm and inviting. The homemade breakfast was a highlight—absolutely delicious and full of flavor. We will stay again longer next time.

Reviewed on Jan 22, 2026

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Save 100% on your flight
Price was $1,913, price is now $1,179 per person
$1,179
per person
May 16 - May 23
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
8.4/10 Very Good! (1,437 reviews)
No complaints excellent

Reviewed on Feb 26, 2026

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Bella Vista
Price was $1,321, price is now $851 per person
$851
per person
May 16 - May 23
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
9/10 Wonderful! (4,515 reviews)
Dated rooms, needs new bedding and smart tv’s, lacked adequate towels. Pros, great breakfast and friendly dining hall staff especially Eddison.

Reviewed on Mar 2, 2026

Hyatt Regency Panama City

Hyatt Regency Panama City

4.5 out of 5
Bella Vista
Price was $1,447, price is now $1,017 per person
$1,017
per person
May 16 - May 23
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
9.8/10 Exceptional! (204 reviews)
Great hotel. Very clean, nice breakfast, free valet parking.

Reviewed on Mar 1, 2026

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
San Francisco
Price was $1,247, price is now $929 per person
$929
per person
May 16 - May 23
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
9/10 Wonderful! (1,005 reviews)
Courteous staff. Lovely property

Reviewed on Mar 1, 2026

Where to stay in Punta Paitilla

Find the best Punta Paitilla areas and neighborhoods for the activities you enjoy most. Learn more about Punta Paitilla
View of the Panama City Old Town

Casco Viejo

4.5/5(178 area reviews)

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Find hotels in Casco Viejo

Punta Paitilla Hotel Deals

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
$159 nightly
The price is $175 total per night from Apr 2 to Apr 3
$175 total
Apr 2 - Apr 3
Total with taxes and fees
9/10 Wonderful! (1,004 reviews)
Courteous staff. Lovely property

Reviewed on Mar 1, 2026

Las Americas Golden Tower Panama
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Avenida Balboa Con Multicentro Panama City Panama
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $153 total per night from Mar 3 to Mar 4
$153 total
Mar 3 - Mar 4
Total with taxes and fees
8.6/10 Excellent! (1,583 reviews)
Simple room decor with the hotel showing its vintage in various areas. The buffet breakfast was very good with various hot and cold items. The Megapolis Mall across from the hotel is also in need of updating.

Reviewed on Feb 28, 2026

Decapolis Hotel Panama City
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

3.5 out of 5
Italy Avenue, Punta Paitilla Panama City Panama
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $119 total per night from Mar 26 to Mar 27
$119 total
Mar 26 - Mar 27
Total with taxes and fees
9.4/10 Exceptional! (2,133 reviews)
excellent value for the money with a very good breakfast buffet

Reviewed on Mar 2, 2026

Plaza Paitilla Inn Hotel
See all 1,575 properties in Punta Paitilla
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Punta Paitilla

Rainy day in Panama City but the charm of this city never ends. A beautiful rainbow over the city invites us to spend a bright day in paradise. #LifeAtExpedia

Multiplaza Pacific Mall

During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Multiplaza Pacific Mall
Panama City night skyline

Avenida Balboa

You can find the perfect gifts to bring home at Avenida Balboa during your trip to Panama City. While you're in the area, wander around the natural setting.

Avenida Balboa
Old and traditional Yatch Club at Cinta Costera, Panama City, Panama.

Cinta Costera

Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.

Cinta Costera

Things to do

Boat tour in the Panama Canal to Monkeys and sloths islands

Boat tour in the Panama Canal to Monkeys and sloths islands

$74
per adult
100% of travellers recommend
Boat tour in the Panama Canal to Monkeys and sloths islands
Panama City: Poin Full Package Experience

Panama City: Poin Full Package Experience

$155
per adult
98% of travellers recommend
Panama City: Poin Full Package Experience
Panama City: Poin Glass Observation Deck Ticket with VR Tour

Panama City: Poin Glass Observation Deck Ticket with VR Tour

$32
per adult
100% of travellers recommend
Panama City: Poin Glass Observation Deck Ticket with VR Tour
See all activities in Panama City
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.