Punta Paitilla Vacations from $867

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Your Punta Paitilla Vacation

The easiest way to experience this exciting city is with a tailor-made Punta Paitilla vacation package. Base yourself in the neighborhood of Marbella, which is good for cafes, walking and dining or go someplace else — our package deals are all about you. Every trip to Punta Paitilla needs a well-planned itinerary. Fill yours with attractions like Miraflores Locks, Bridge of the Americas and Metropolitan Cathedral of Panama. Expedia will help you escape your daily routine. Tailor your vacation to Punta Paitilla to suit your travel style, whatever that may be.

The Latest Punta Paitilla Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

$867
per person
Nov 20 - Nov 27
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
8.6/10 Excellent! (1,811 reviews)
Megapolis Hotel Panamá

Megapolis Hotel Panamá

San Francisco
Save 100% on your flight
$1,097
per person
Oct 19 - Oct 26
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
8.4/10 Very Good! (1,693 reviews)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Casco Viejo
Save 100% on your flight
$1,206
per person
Nov 20 - Nov 27
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
9/10 Wonderful! (1,012 reviews)
Very clean, spacious and comfortable rooms.

Reviewed on Sep 11, 2026

Central Hotel Bocas del Toro

Central Hotel Bocas del Toro

Save 100% on your flight
$1,741
per person
Oct 22 - Oct 27
found 2 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
No reviews
Decapolis Hotel Panama City

Decapolis Hotel Panama City

San Francisco
$950
per person
Oct 19 - Oct 26
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
8.6/10 Excellent! (1,708 reviews)
The SPA do not work. The Jaccuzi do not work

Reviewed on Sep 11, 2026

Where to stay in Punta Paitilla

Find the best Punta Paitilla areas and neighborhoods for the activities you enjoy most. Learn more about Punta Paitilla
A waterfront cityscape with historic buildings and a prominent clock tower.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

A cityscape with modern skyscrapers, including a distinctive twisting tower.

Bella Vista

1 out of top 10 points of interest in this area

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station.

A city skyline with modern high-rise buildings and a river in the foreground.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

A bridge over a body of water with several boats.

San Francisco

1 out of top 10 points of interest in this area

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

A coastal city skyline with high-rise buildings, palm trees, and a clear sky.

Calidonia

2 out of top 10 points of interest in this area

You might enjoy the shopping while in Calidonia. Via Espana is a notable sight, and you can get around town at Lotería Station or Santo Tomás Station to see more of the city.

Punta Paitilla Hotel Deals

Megapolis Hotel Panamá

Megapolis Hotel Panamá

Avenida Balboa Panama City
Fully refundableReserve now, pay when you stay
$130 nightly
$130 total
Sep 29 - Sep 30
Total with taxes and fees
Megapolis Hotel Panamá
Decapolis Hotel Panama City

Decapolis Hotel Panama City

Avenida Balboa Con Multicentro Panama City Panama
Fully refundableReserve now, pay when you stay
$101 nightly
$111 total
Sep 28 - Sep 29
Total with taxes and fees
8.6/10 Excellent! (1,719 reviews)
"The SPA do not work. The Jaccuzi do not work"

Reviewed on Sep 11, 2026

Decapolis Hotel Panama City
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

Av. Balboa con Calle 53 Panama City Panama
Fully refundableReserve now, pay when you stay
$132 nightly
$145 total
Oct 4 - Oct 5
Total with taxes and fees
9/10 Wonderful! (1,107 reviews)
"Thanks"

Reviewed on Sep 8, 2026

Las Americas Golden Tower Panama
See all 1,822 properties in Punta Paitilla
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Punta Paitilla attractions

Pacific Center

You can enjoy retail therapy at Pacific Center during your visit to Panama City. You can enjoy the restaurants while in the area.
See properties

Things to do

Panama Canal: The Most Complete Monkey Island Experience

Panama Canal: The Most Complete Wildlife Experience

$48
per adult
96% of travellers recommend
Panama Canal: The Most Complete Wildlife Experience
From Panama City: San Blas Island Hopping Day Tour

From Panama City: San Blas Island Hopping Day Tour

$145
per adult
98% of travellers recommend
From Panama City: San Blas Island Hopping Day Tour
Panama City: Poin Glass Observation Deck Ticket with VR Tour

Panama City: Poin Glass Observation Deck Ticket with VR Tour

$32
per adult
100% of travellers recommend
Panama City: Poin Glass Observation Deck Ticket with VR Tour
See all activities in Panama City
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.