Punta Paitilla Vacations from $662

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Your Punta Paitilla Vacation

The easiest way to experience this exciting city is with a tailor-made Punta Paitilla vacation package. Base yourself in the neighborhood of Marbella, which is good for cafes, walking and dining or go someplace else — our package deals are all about you. Every trip to Punta Paitilla needs a well-planned itinerary. Fill yours with attractions like Miraflores Locks, Bridge of the Americas and Metropolitan Cathedral of Panama. Expedia will help you escape your daily routine. Tailor your vacation to Punta Paitilla to suit your travel style, whatever that may be.

The Latest Punta Paitilla Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Mahogany Suites

Mahogany Suites

2 out of 5
Price was $1,168, price is now $662 per person
$662
per person
Mar 26 - Mar 30
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
10/10 Exceptional! (1 review)
Excellent apartment on a golf resort. 5 Star.

Reviewed on Jan 28, 2026

Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
Save 100% on your flight
Price was $1,284, price is now $744 per person
$744
per person
Mar 25 - Apr 1
found 2 hours ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
9.8/10 Exceptional! (60 reviews)
We stayed one night and it exceeded our expectations. The owners were incredibly friendly and easy to contact, making us feel right at home. Everything was spotless, and the atmosphere was warm and inviting. The homemade breakfast was a highlight—absolutely delicious and full of flavor. We will stay again longer next time.

Reviewed on Jan 22, 2026

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $1,994, price is now $1,363 per person
$1,363
per person
Apr 1 - Apr 6
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9/10 Wonderful! (1,002 reviews)
Room was clean and comfortable. Staff was very friendly and helpful. Breakfast was very good

Reviewed on Feb 15, 2026

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Bella Vista
Price was $1,232, price is now $846 per person
$846
per person
Apr 1 - Apr 6
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9/10 Wonderful! (4,515 reviews)
Rooms were clean. Breakfast was excellent

Reviewed on Feb 18, 2026

Casa Lefevre By Wynwood House

Casa Lefevre By Wynwood House

3.5 out of 5
Casco Viejo
Save 100% on your flight
Price was $2,684, price is now $1,847 per person
$1,847
per person
Apr 3 - Apr 9
found 1 day ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
8.8/10 Excellent! (3 reviews)
Staff was courteous, and the room was very beautiful. Would stay here again!

Reviewed on Dec 31, 2025

Where to stay in Punta Paitilla

Find the best Punta Paitilla areas and neighborhoods for the activities you enjoy most. Learn more about Punta Paitilla
View of the Panama City Old Town

Casco Viejo

4.5/5(178 area reviews)

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Find hotels in Casco Viejo

Punta Paitilla Hotel Deals

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $187 total per night from Mar 15 to Mar 16
$187 total
Mar 15 - Mar 16
Total with taxes and fees
9/10 Wonderful! (1,037 reviews)
Tremendous views of the city from our 21st floor hotel room. Huge breakfast with large selection. The room was super comfortable and spacious. Loved the layout. The beds super comfortable The staff was excellent.

Reviewed on Feb 18, 2026

Las Americas Golden Tower Panama
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Avenida Balboa Con Multicentro Panama City Panama
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $128 total per night from Feb 19 to Feb 20
$128 total
Feb 19 - Feb 20
Total with taxes and fees
8.6/10 Excellent! (1,558 reviews)
Yes staff not supportive

Reviewed on Feb 10, 2026

Decapolis Hotel Panama City
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

3.5 out of 5
Italy Avenue, Punta Paitilla Panama City Panama
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $119 total per night from Mar 12 to Mar 13
$119 total
Mar 12 - Mar 13
Total with taxes and fees
9.4/10 Exceptional! (2,143 reviews)
Room and location are excellent. Everything was clean and nice. Staff were friendly. No issues at all. Thank you

Reviewed on Feb 18, 2026

Plaza Paitilla Inn Hotel
See all 1,548 properties in Punta Paitilla
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Punta Paitilla

Rainy day in Panama City but the charm of this city never ends. A beautiful rainbow over the city invites us to spend a bright day in paradise. #LifeAtExpedia

Multiplaza Pacific Mall

You can enjoy some retail therapy when you visit Multiplaza Pacific Mall, a popular shopping spot in Panama City. You can enjoy the restaurants while in the area.

Multiplaza Pacific Mall
Causeway, Amador, Panama

Amador Causeway

You can learn about the history of Ancon with a stop at Amador Causeway. Stroll along the seaside or visit the shops in this vibrant area.

Amador Causeway
Panama City night skyline

Avenida Balboa

You can find the perfect gifts to bring home at Avenida Balboa during your trip to Panama City. While you're in the area, wander around the natural setting.

Avenida Balboa

Things to do

Boat tour in the Panama Canal to Monkeys and sloths islands

Boat tour in the Panama Canal to Monkeys and sloths islands

$74
per adult
100% of travellers recommend
Boat tour in the Panama Canal to Monkeys and sloths islands
Panama City: Poin Full Package Experience

Panama City: Poin Full Package Experience

$155
per adult
98% of travellers recommend
Panama City: Poin Full Package Experience
Panama City: Poin Glass Observation Deck Ticket with VR Tour

Panama City: Poin Glass Observation Deck Ticket with VR Tour

$32
per adult
100% of travellers recommend
Panama City: Poin Glass Observation Deck Ticket with VR Tour
See all activities in Panama City
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.