Punta Paitilla Vacations from $662

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Your Punta Paitilla Vacation

The easiest way to experience this exciting city is with a tailor-made Punta Paitilla vacation package. Base yourself in the neighborhood of Marbella, which is good for cafes, walking and dining or go someplace else — our package deals are all about you. Every trip to Punta Paitilla needs a well-planned itinerary. Fill yours with attractions like Miraflores Locks, Bridge of the Americas and Metropolitan Cathedral of Panama. Expedia will help you escape your daily routine. Tailor your vacation to Punta Paitilla to suit your travel style, whatever that may be.

The Latest Punta Paitilla Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Mahogany Suites
Villa Botero By Casa Mojito B&B
Central Hotel Panama Casco Viejo
Hotel Riu Plaza Panama
Casa Lefevre By Wynwood House

Where to stay in Punta Paitilla

Find the best Punta Paitilla areas and neighborhoods for the activities you enjoy most. Learn more about Punta Paitilla

Punta Paitilla Hotel Deals

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $187 total per night from Mar 15 to Mar 16
$187 total
Mar 15 - Mar 16
Total with taxes and fees
9/10 Wonderful! (1,037 reviews)
Tremendous views of the city from our 21st floor hotel room. Huge breakfast with large selection. The room was super comfortable and spacious. Loved the layout. The beds super comfortable The staff was excellent.

Reviewed on Feb 18, 2026

Las Americas Golden Tower Panama
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Avenida Balboa Con Multicentro Panama City Panama
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $128 total per night from Feb 19 to Feb 20
$128 total
Feb 19 - Feb 20
Total with taxes and fees
8.6/10 Excellent! (1,558 reviews)
Yes staff not supportive

Reviewed on Feb 10, 2026

Decapolis Hotel Panama City
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

3.5 out of 5
Italy Avenue, Punta Paitilla Panama City Panama
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $119 total per night from Mar 12 to Mar 13
$119 total
Mar 12 - Mar 13
Total with taxes and fees
9.4/10 Exceptional! (2,143 reviews)
Room and location are excellent. Everything was clean and nice. Staff were friendly. No issues at all. Thank you

Reviewed on Feb 18, 2026

Plaza Paitilla Inn Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Punta Paitilla

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.