Title: Visit Rio en Medio: 2026 Travel Guide for Rio en Medio, Santa Fe | Expedia.com [Hotels in Rio en Medio](https://expedia.com/Rio-En-Medio-Hotels.d553248634983078948.Travel-Guide-Hotels)[Vacation Rentals in Rio en Medio](https://expedia.com/Rio-En-Medio-Vacation-Rentals.d553248634983078948.Travel-Guide-VacationRentals)[Car Rentals in Rio en Medio](https://expedia.com/Car-Rentals-In-Rio-En-Medio.d553248634983078948.Car-Rental-Guide)[Rio en Medio Vacation Packages](https://expedia.com/Rio-En-Medio.d553248634983078948.Destination-Travel-Guides) # Rio en Medio, NM ## Travel Guide ## Visit Rio en Medio Things to do ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=DX_SPRING_PROMO_553248634983078948) - Rio en Medio Hotel Deals - Vacation Rentals in Rio en Medio ![La Fonda on the Plaza](https://images.trvl-media.com/lodging/1000000/10000/6700/6690/17bd5948_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### La Fonda on the Plaza 100 E San Francisco St Santa Fe NM $209 nightly $241 total Mar 8 - Mar 9 Total with taxes and fees Book a stay at this historic hotel in Santa Fe. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the restaurant and the helpful staff in ... 9.2/10 Wonderful! (1,104 reviews) Amazing service Reviewed on Feb 21, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F8%2F2026&endDate=3%2F9%2F2026&selected=6690&PinnedHotelID=6690&HadPinnedHotel=true®ionId=553248634983078948) ![Drury Plaza Hotel in Santa Fe](https://images.trvl-media.com/lodging/9000000/8200000/8199200/8199136/8f424b4a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Drury Plaza Hotel in Santa Fe 828 Paseo de Peralta Santa Fe NM Fully refundableReserve now, pay when you stay $149 nightly $171 total Feb 26 - Feb 27 Total with taxes and fees Book a stay at this business-friendly hotel in Santa Fe. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the pool in our ... 9.4/10 Exceptional! (1,442 reviews) Room was clean and comfortable except it smelled like camp as the smoke from the wood burning fireplace downstairs made its way into the central air conditioning system and smoked up the room. Not the expected scent unless you are out camping! Reviewed on Feb 17, 2026 [](https://expedia.com/Hotel-Search?startDate=2%2F26%2F2026&endDate=2%2F27%2F2026&selected=8199136&PinnedHotelID=8199136&HadPinnedHotel=true®ionId=553248634983078948) ![Inn and Spa at Loretto](https://images.trvl-media.com/lodging/1000000/30000/26300/26264/b1f202d6_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Inn and Spa at Loretto 211 Old Santa Fe Trail Santa Fe NM $262 nightly $301 total Feb 23 - Feb 24 Total with taxes and fees Book a stay at this business-friendly hotel in Santa Fe. Enjoy breakfast (surcharge), a fitness center, and onsite spa services. Our guests praise the restaurant ... 9/10 Wonderful! (1,000 reviews) The Hotel was amazing - the rooms, staff and amenities were on point. Plenty of nice shops in the hotel and right next door to the Loretto Chapel. Reviewed on Feb 16, 2026 [](https://expedia.com/Hotel-Search?startDate=2%2F23%2F2026&endDate=2%2F24%2F2026&selected=26264&PinnedHotelID=26264&HadPinnedHotel=true®ionId=553248634983078948) [See all 1,625 properties in Rio en Medio](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=2%2F22%2F2026&endDate=2%2F23%2F2026®ionId=553248634983078948) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Southwestern style home! We are your home away from home & close to everything.](https://images.trvl-media.com/lodging/112000000/111410000/111402700/111402613/061507dd_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Southwestern style home! We are your home away from home & close to everything. Santa Fe NM Book a stay at this family-friendly vacation home in Santa Fe. Enjoy laundry facilities, an in-room coffeemaker, and air conditioning. Popular attractions Santa ... 9.6/10 Exceptional! (24 reviews) The place was the cleanest I'd ever seen, and was like staying in a model home. It was close to everything we would ever want to see or do. The owner even had the house warmed up for us when we arrived. Would totally recommend. Reviewed on Jan 22, 2026 [](https://expedia.com/Santa-Fe-Hotels-Southwestern-Style-Home-We-Are-Your-Home-Away-From-Home-Close-To-Everything.h111402613.Hotel-Information) ![Visitors Love the Location, I Love the View!](https://images.trvl-media.com/lodging/28000000/27490000/27489100/27489064/83009d59_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Visitors Love the Location, I Love the View! Santa Fe NM Book a stay at this ski condo in Santa Fe. Enjoy free WiFi, laundry facilities, and ski-in/ski-out access. Our guests praise the helpful staff in our reviews. ... 9.8/10 Exceptional! (391 reviews) No hassles with anything. Easy check in, check out, and lots of info available. Reviewed on Feb 16, 2026 [](https://expedia.com/Santa-Fe-Hotels-Mountain-View-Plus-A-Perfect-Location.h27489064.Hotel-Information) ![*Historic Adobe w Hot Tub & Bikes, Centrally located on Canyon Road* ](https://images.trvl-media.com/lodging/20000000/19640000/19639700/19639668/fe8c5ace_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### \*Historic Adobe w Hot Tub & Bikes, Centrally located on Canyon Road\* Santa Fe NM Stay at this vacation home in Santa Fe. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Santa Fe Plaza and Cristo Rey are located ... 9.8/10 Exceptional! (272 reviews) Our host, Kay kindly reached out & introduced herself prior to our stay. As we were in the middle of a winter storm, she communicated with us to make sure all was well. She accommodated our every need. Very comfy and cozy. I was extremely pleased with this adobe casita. I highly recommend and I myself, ... Reviewed on Feb 3, 2026 [](https://expedia.com/Santa-Fe-Hotels-Historic-Adobe-W-Hot-Tub-Bikes.h19639668.Hotel-Information) [See all properties in Rio en Medio](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=553248634983078948&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Rio en Medio hotel availability [Tonight ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983078948&startDate=2026-02-21&endDate=2026-02-22)[Feb 21 - Feb 22](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983078948&startDate=2026-02-21&endDate=2026-02-22) [Tomorrow night ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983078948&startDate=2026-02-22&endDate=2026-02-23)[Feb 22 - Feb 23](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983078948&startDate=2026-02-22&endDate=2026-02-23) [Next weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983078948&startDate=2%2F27%2F2026&endDate=3%2F1%2F2026)[Feb 27 - Mar 1](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983078948&startDate=2%2F27%2F2026&endDate=3%2F1%2F2026) ### Popular places to visit ![Santa Fe Plaza which includes religious elements, a church or cathedral and street scenes](https://images.trvl-media.com/place/6128782/d6aea3b0-b1ae-4f32-b83f-5a705dcfc3a0.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Santa Fe Plaza Home to many landmarks in the heart of the city, this spacious square evokes echoes of the Spanish colonial era with its markets, bandstand and live music. [](https://expedia.com/Santa-Fe-Plaza-Downtown-Santa-Fe.d6128782.Vacation-Attraction) ![Loretto Chapel showing a church or cathedral](https://images.trvl-media.com/place/502844/7b32c123-0148-4e2e-bb93-62ffcb0886fa.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Loretto Chapel A mysterious spiral staircase with no known origin is the highlight of this former church that now acts as a wedding chapel and museum. [](https://expedia.com/Loretto-Chapel-Downtown-Santa-Fe.d502844.Vacation-Attraction) ![A peak inside Meow Wolf. Love this place!](https://images.trvl-media.com/place/180028/f96100b6-583d-4452-9af0-e211cc9403ec.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Meow Wolf You can spend an afternoon browsing the exhibits at Meow Wolf during your travels in Santa Fe. Visit the stunning cathedral and shops in this walkable area. [](https://expedia.com/Meow-Wolf-Southside.d553248633953854365.Vacation-Attraction) ![View of Jemez Mountains from Santa Fe, NM](https://images.trvl-media.com/place/553248621555875014/27fd96a4-3acc-4cf4-9f12-ad53549db70c.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Ski Santa Fe Hit the slopes at Ski Santa Fe during your trip to Santa Fe. Discover the top-notch restaurants and acclaimed art scene in this walkable area. [](https://expedia.com/Ski-Santa-Fe-Santa-Fe.d553248621555875014.Vacation-Attraction) ![Canyon Road featuring street scenes](https://images.trvl-media.com/place/6177623/ff96860f-00ca-4167-8244-2ee9f032bfb6.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Canyon Road This charming road was once lined with typical adobe residences. Now art galleries, studios, restaurants and boutiques make it the most exclusive part of town. [](https://expedia.com/Canyon-Road-Historic-Eastside.d6177623.Vacation-Attraction) ![Santa Fe Opera showing a city](https://images.trvl-media.com/place/6064365/e18683fd-9e3d-4a39-a3fc-3598586073e8.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Santa Fe Opera Listen to the enchanting sounds of classic opera in an open-air theater with views of the Jemez Mountains, the sunset and the stars. [](https://expedia.com/Santa-Fe-Opera-Santa-Fe.d6064365.Vacation-Attraction) ### Things to do ![Santa Fe: Meow Wolf's House of Eternal Return Ticket](https://mediaim.expedia.com/localexpert/49038609/547e1cc9-1244-4985-97f2-f18394799fcd.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Santa Fe: Meow Wolf The House of Eternal Return Ticket $45 per adult **100%** of travellers recommend [](https://expedia.com/things-to-do/santa-fe-meow-wolf-the-house-of-eternal-return-ticket.a49038609.activity-details) ![Santa Fe Self-Guided Walking Audio Tour](https://mediaim.expedia.com/localexpert/47267764/87247edb-6778-4e6e-b528-d86905e14034.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Santa Fe Self-Guided App-Based Walking Audio Tour $15 per traveler **100%** of travellers recommend [](https://expedia.com/things-to-do/santa-fe-self-guided-app-based-walking-audio-tour.a47267764.activity-details) ![Make Your Own Stained Glass Honeycomb](https://mediaim.expedia.com/localexpert/47648896/0d1171aa-223b-4d69-904d-97f46916a7a5.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Make Your Own Stained Glass Honeycomb $100 per adult [](https://expedia.com/things-to-do/make-your-own-stained-glass-honeycomb.a47648896.activity-details) ![Exploring Sante Fe Gardens](https://mediaim.expedia.com/localexpert/50651092/25e94bb3-dd6c-4cc2-93b7-452bfdd72540.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Santa Fe Botanical Garden General Admission Ticket $18 per adult [](https://expedia.com/things-to-do/santa-fe-botanical-garden-general-admission-ticket.a50651092.activity-details) ![Tumbleroot Brewery and Distillery Tour and Tasting](https://mediaim.expedia.com/localexpert/5276907/3470e18c-233c-44a4-843b-b6ba2acac370.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Tumbleroot Brewery and Distillery Tour and Tasting $18 per adult **100%** of travellers recommend [](https://expedia.com/things-to-do/tumbleroot-brewery-and-distillery-tour-and-tasting.a5276907.activity-details) ![We start the tour on the Plaza](https://mediaim.expedia.com/localexpert/48704706/50911f31-d1ac-44e0-8184-5333aa36ec9e.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Willa Cather's Walking Tour in Santa Fe $50 per adult [](https://expedia.com/things-to-do/willa-cathers-walking-tour-in-santa-fe.a48704706.activity-details) [See all activities in Rio en Medio](https://expedia.com/Things-To-Do-In-Rio-En-Medio.d553248634983078948.Travel-Guide-Activities) ## Cities near Rio en Medio ![Santa Fe which includes a monument, a garden and a memorial](https://images.trvl-media.com/place/180028/4a0f3a98-c0ed-4030-8335-710343ef8149.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Santa Fe - Cities near Rio en Medio - Places of interest [Santa Fe](https://expedia.com/Santa-Fe.dx180028) - [Santa Fe Plaza ](https://expedia.com/Santa-Fe-Plaza-Downtown-Santa-Fe.d6128782.Vacation-Attraction) - [Loretto Chapel ](https://expedia.com/Loretto-Chapel-Downtown-Santa-Fe.d502844.Vacation-Attraction) - [Meow Wolf ](https://expedia.com/Meow-Wolf-Southside.d553248633953854365.Vacation-Attraction) - [Ski Santa Fe ](https://expedia.com/Ski-Santa-Fe-Santa-Fe.d553248621555875014.Vacation-Attraction) - [Canyon Road ](https://expedia.com/Canyon-Road-Historic-Eastside.d6177623.Vacation-Attraction) - [Santa Fe Opera ](https://expedia.com/Santa-Fe-Opera-Santa-Fe.d6064365.Vacation-Attraction) - [Santa Fe Railyard ](https://expedia.com/Santa-Fe-Railyard-Downtown-Santa-Fe.d553248621533119226.Vacation-Attraction) - [Cathedral Basilica of Saint Francis of Assisi ](https://expedia.com/Cathedral-Basilica-Of-Saint-Francis-Of-Assisi-Downtown-Santa-Fe.d502842.Vacation-Attraction) - [Rio Grande ](https://expedia.com/Rio-Grande.d553248621532643072.Vacation-Attraction) - [Bandelier National Monument ](https://expedia.com/Bandelier-National-Monument-New-Mexico.d6093677.Vacation-Attraction) - [Georgia O'Keefe Museum ](https://expedia.com/Georgia-OKeefe-Museum-Downtown-Santa-Fe.d6064359.Vacation-Attraction) - [Carson National Forest ](https://expedia.com/Carson-National-Forest-New-Mexico.d6093649.Vacation-Attraction) - [New Mexico State Capitol ](https://expedia.com/New-Mexico-State-Capitol-Downtown-Santa-Fe.d502829.Vacation-Attraction) - [Lowlows Lowrider Art Place ](https://expedia.com/Lowlows-Lowrider-Art-Place-Chimayo.d6328184.Vacation-Attraction) - [Cities of Gold Casino ](https://expedia.com/Cities-Of-Gold-Casino-Santa-Fe.d553248621532645938.Vacation-Attraction) - [Palace of the Governors ](https://expedia.com/Palace-Of-The-Governors-Downtown-Santa-Fe.d502831.Vacation-Attraction) - [Santuario de Chimayo ](https://expedia.com/Santuario-De-Chimayo-Chimayo.d6093681.Vacation-Attraction) - [New Mexico Museum of Art ](https://expedia.com/New-Mexico-Museum-Of-Art-Downtown-Santa-Fe.d6064361.Vacation-Attraction) - [Nambe Falls ](https://expedia.com/Nambe-Falls-Santa-Fe.d553248621561874340.Vacation-Attraction) - [Old Fort Marcy Park ](https://expedia.com/Old-Fort-Marcy-Park-North-Hills.d507499.Vacation-Attraction) - [Hyde Memorial State Park ](https://expedia.com/Hyde-Memorial-State-Park-Santa-Fe.d553248621532645914.Vacation-Attraction) - [Santa Fe National Cemetery ](https://expedia.com/Santa-Fe-National-Cemetery-Northeast-Santa-Fe.d553248621532645896.Vacation-Attraction) - [Lensic Performing Arts Center ](https://expedia.com/Lensic-Performing-Arts-Center-Downtown-Santa-Fe.d6064367.Vacation-Attraction) - [Sweeney Convention Center ](https://expedia.com/Sweeney-Convention-Center-Downtown-Santa-Fe.d847067212910157824.Vacation-Attraction) - [St. John's College ](https://expedia.com/St-Johns-College-Santa-Fe.d502848.Vacation-Attraction) - [San Miguel Mission ](https://expedia.com/San-Miguel-Mission-Downtown-Santa-Fe.d502830.Vacation-Attraction) - [Towa Golf Resort ](https://expedia.com/Towa-Golf-Resort-Santa-Fe.d553248621532645937.Vacation-Attraction) - [Museum of International Folk Art ](https://expedia.com/Museum-Of-International-Folk-Art-Southeast-Santa-Fe.d502837.Vacation-Attraction) - [Harrell House of Natural Oddities and Bug Museum ](https://expedia.com/Harrell-House-Of-Natural-Oddities-And-Bug-Museum-West-Guadaloupe.d6328553.Vacation-Attraction) - [International Museum of Collage ](https://expedia.com/International-Museum-Of-Collage-Southside.d553248621532645433.Vacation-Attraction) - [Institute of American Indian Arts ](https://expedia.com/Institute-Of-American-Indian-Arts-Downtown-Santa-Fe.d502834.Vacation-Attraction) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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