Title: Río Sambú Tours - Book Now | Expedia.com [Río Sambú Hotels](https://expedia.com/Rio-Sambu-Hotels.0-l553248621532964868-0.Travel-Guide-Filter-Hotels)[Flights to Panama](https://expedia.com/Destinations-In-Panama.d142.Flight-Destinations)[Things to do in Panama](https://expedia.com/Things-To-Do-In-Panama.d142.Travel-Guide-Activities)[Car Rentals in Río Sambú](https://expedia.com/Car-Rentals-In-Rio-Sambu.d553248621532964868.Car-Rental-Guide)[Panama Vacations](https://expedia.com/Panama.d142.Destination-Travel-Guides) # Río Sambú Tours ## Visit Río Sambú Activities --- --- ## Plan a trip to see Río Sambú Price found within the past 48 hours. Click for updated prices. ![Villa Botero By Casa Mojito B&B](https://images.trvl-media.com/lodging/12000000/11930000/11927200/11927153/393d35f8_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Villa Botero By Casa Mojito B&B Save 100% on your flight $673 per person May 4 - May 11 found 1 day ago Roundtrip flight included Miami (MIA) to Panama City (PTY) 9.8/10 Exceptional! (60 reviews) We stayed one night and it exceeded our expectations. The owners were incredibly friendly and easy to contact, making us feel right at home. Everything was spotless, and the atmosphere was warm and inviting. The homemade breakfast was a highlight—absolutely delicious and full of flavor. We will stay again longer next time. Reviewed on Jan 22, 2026 ![Mahogany Suites](https://images.trvl-media.com/lodging/119000000/118410000/118402400/118402387/179ad971_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Mahogany Suites $711 per person Apr 8 - Apr 12 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 10/10 Exceptional! (1 review) Excellent apartment on a golf resort. 5 Star. Reviewed on Jan 28, 2026 ![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Central Hotel Panama Casco Viejo Casco Viejo Save 100% on your flight $1,098 per person May 11 - May 16 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 9/10 Wonderful! (1,002 reviews) Room was amazing, beautiful hotel in the center of town. Service also very good and attentive. Amazing breakfast. Reviewed on Feb 24, 2026 ### Popular places to visit #### Pirre Station You can find out about the history of La Palma when you stop by Pirre Station. [](https://expedia.com/Pirre-Station-La-Palma.d553248621532964867.Vacation-Attraction) --- ## Best Lodging Options Near Río Sambú ## Check availability on hotels close to Río Sambú [Tonight ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621532964868&startDate=2026-02-28&endDate=2026-03-01)[Feb 28 - Mar 1](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621532964868&startDate=2026-02-28&endDate=2026-03-01) [Tomorrow night ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621532964868&startDate=2026-03-01&endDate=2026-02-02)[Mar 1 - Mar 2](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621532964868&startDate=2026-03-01&endDate=2026-02-02) [Next weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621532964868&startDate=3%2F6%2F2026&endDate=3%2F8%2F2026)[Mar 6 - Mar 8](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621532964868&startDate=3%2F6%2F2026&endDate=3%2F8%2F2026) ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Riu Plaza Panama Calle 50, Urb. Marbella Panama City Panama [](https://expedia.com/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Hotel El Panama by Faranda Grand, a member of Radisson Individuals](https://images.trvl-media.com/lodging/1000000/10000/7200/7164/cfc3400a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel El Panama by Faranda Grand, a member of Radisson Individuals Via Espana 111 Panama City Panama [](https://expedia.com/Panama-City-Hotels-Hotel-El-Panama-By-Faranda-Grand.h7164.Hotel-Information) ![Crowne Plaza Panama Airport by IHG](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Crowne Plaza Panama Airport by IHG Ave. Domingo Diaz Tocumen Panama [](https://expedia.com/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Sheraton Grand Panama](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/179e52b4_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Sheraton Grand Panama Via Israel And 77th Street Panama City Panama [](https://expedia.com/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) ![W Panama](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### W Panama Calle Aquilino de la Guardia & Calle 50 Panama City [](https://expedia.com/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) ![Waymore Hotel Spa & Casino](https://images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/75048cd3_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Waymore Hotel Spa & Casino Calle Augusto Samuel Boyd y Calle Eusebi Panama City [](https://expedia.com/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information) ![Waldorf Astoria Panama](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/e7e98c5e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Waldorf Astoria Panama 47th St. & Uruguay Street Panama City Panama [](https://expedia.com/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) ![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/493046b7_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Executive Hotel Calle 52 Panama City Panama [](https://expedia.com/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) ![Hotel Riu Playa Blanca - All Inclusive](https://images.trvl-media.com/lodging/8000000/7330000/7326200/7326126/60f3aac3_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Riu Playa Blanca - All Inclusive Finca 43.668 Rio Hato Cocle [](https://expedia.com/Rio-Hato-Hotels-Riu-Playa-Blanca-All-Inclusive.h7326126.Hotel-Information) [See all 3,485 properties in Panama](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=142) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. 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