San Francisco Vacations from $683

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The Latest San Francisco vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Panamonte
Central Hotel Bocas del Toro
Isla Palenque Member of the Cayuga Collection
La Coralina Island House
Central Hotel Panama Casco Viejo
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San Francisco Hotel Deals

Hotel Gran David

Hotel Gran David

3.5 out of 5
Vía Interamericana, Santiago, Veraguas
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $84 total per night from Sep 1 to Sep 2
$84 total
Sep 1 - Sep 2
Total with taxes and fees
Hotel Gran David
Hotel Mykonos Panama

Hotel Mykonos Panama

3.5 out of 5
Panamerican Highway, in front of Ruben Cantu Airport, Nuevo Santiago, Veraguas
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $95 total per night from Sep 3 to Sep 4
$95 total
Sep 3 - Sep 4
Total with taxes and fees
Hotel Mykonos Panama
HOTEL VISTA LAGO

HOTEL VISTA LAGO

3 out of 5
Rincón Largo, La Pena, Santiago de Veraguas
$77 nightly
The price is $84 total per night from Sep 1 to Sep 2
$84 total
Sep 1 - Sep 2
Total with taxes and fees
HOTEL VISTA LAGO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

How to find the best San Francisco package deals?
Start your search for a San Francisco package deal by entering your travel dates and destination under our "Packages" tab. Then add a few filters, like "Property type" and "Popular locations," to fine-tune the results to your exact style. You can also sort by "Package discount" and discover offers that come with unbeatable savings. If you don't find the perfect San Francisco package deal right away, just change your dates and search again. Remember that deals are only available for a limited time, so book early and get your San Francisco adventure off to a flying start.
When to book a vacation package to San Francisco?
Enjoy amazing discounts by booking your flights in advance with Expedia. If spontaneity is more your style, grab one of our last-minute deals for a spur-of-the-moment San Francisco adventure.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.