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Our top choices for San Francisco hotels

A pool area with lounge chairs and a covered seating area, surrounded by modern buildings.

1. Hotel Mykonos Panama

Hotel Mykonos Panama
3.5 star property
Nuevo Santiago
8.8 out of 10, Excellent, (606 reviews)
"The pool was great night. Minor hiccups with ordering pool side drinks."
Canada
Philipp
July 27th, 2026
$74 nightly
The price is $82
Nov 15 - Nov 16
Total with taxes and fees
Hotel Mykonos Panama
A pool surrounded by palm trees and a tiled roof structure.

2. Hotel Gran David

Hotel Gran David
3.5 star property
Santiago
8.6 out of 10, Excellent, (452 reviews)
"Next time we'll definitely spend at least 2 nights. Service were excellent."
United States
CESAR
10 days ago
$79 nightly
The price is $87
Dec 6 - Dec 7
Total with taxes and fees
Hotel Gran David
A swimming pool with a water slide, surrounded by palm trees and lounge chairs.

3. HOTEL VISTA LAGO

HOTEL VISTA LAGO
3.0 star property
La Pena
9.4 out of 10, Exceptional, (128 reviews)
"Garden very nice. Breakfast was very good."
United States
Hedwig
August 30th, 2026
$72 nightly
The price is $80
Nov 15 - Nov 16
Total with taxes and fees
HOTEL VISTA LAGO
A modern lobby with a sofa, armchairs, a desk, and a large window offering a view of the cityscape.

4. Hotel Plaza Los Tucanes

Hotel Plaza Los Tucanes
3.0 star property
Nuevo Santiago
8.8 out of 10, Excellent, (16 reviews)
"Clean room, present staff, and in a central área."
United States
Alexandria
7 days ago
$58 nightly
The price is $63
Nov 15 - Nov 16
Total with taxes and fees
Hotel Plaza Los Tucanes
Restaurant

5. Hotel Anachoreo

Hotel Anachoreo
3.0 star property
Santa Fe
9.6 out of 10, Exceptional, (47 reviews)
"Great property location. Bath areas great."
United States
michael
July 24th, 2026
$85 nightly
The price is $93
Nov 16 - Nov 17
Total with taxes and fees
Hotel Anachoreo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Hotels recommended for families in San Francisco

A pool area with lounge chairs and a covered seating area, surrounded by modern buildings.

Hotel Mykonos Panama

Hotel Mykonos Panama
3.5 star property
Nuevo Santiago
8.8 out of 10, Excellent, (606)
$74 nightly
The price is $82
Nov 15 - Nov 16
Total with taxes and fees
Hotel Mykonos Panama
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Top San Francisco Hotel Reviews

Hotel Gran David

Hotel Gran David

8/10 Good
"Everything was clean and organized. Some of the front desk staff was friendly . Breakfast was well prepared although I do feel that coffee refills should be free of charge when you have spent the night."
Michelle 2-night trip
Posted 1 day ago
Hotel Gran David

More cheap stays in San Francisco

La Qhia Eco Retreat

La Qhia Eco Retreat

Barriada el Cerro A 100 Mts De Santa Fe Veraguas
Get rates
8.2/10 Very Good! (22 reviews)

Hotels in San Francisco with star-rating

Frequently asked questions

What is the best area to stay in San Francisco?
The best area to stay in San Francisco, Veraguas, Panama, is directly within the town center due to its convenient access to local amenities and the main road.

The town center of San Francisco is relatively compact, with the main street, Calle Central, serving as the hub of activity. Here, you'll find local eateries, small shops, and the central church, Iglesia San Francisco de Asís. It's an ideal base for exploring the surrounding natural attractions.

This area is particularly well-suited for solo travelers or couples who appreciate easy access to local culture and services.
When is the best time to go to San Francisco?
The best time to visit San Francisco, Veraguas, Panama, is during the dry season, which runs from December to April.

This period offers consistently sunny weather and lower humidity, making it ideal for outdoor activities like exploring the surrounding natural parks and enjoying the local culture. The days are warm, and evenings are pleasant, great for dining outdoors or leisurely strolls.

Travelers looking for a relaxed experience will find this time particularly appealing.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in San Francisco.
How much is the nightly rate at a San Francisco hotel?
Prices for hotels in San Francisco often vary, but you can find a great deal from $63 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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