Sant'Eustachio Vacations

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Your SantEustachio Vacation

A well-liked picturesque neighborhood, SantEustachio is all about cafes, history and bars and pubs. Lock in a vacation package to SantEustachio and get set to discover all of that and more. Start your trip to SantEustachio by checking out nearby attractions such as St. Peters Basilica, Roman Forum and Pantheon. Stop daydreaming and start doing. When you're ready to book your dream vacation to SantEustachio, Expedia is here to help.

Where to stay in Sant'Eustachio

Find the best Sant'Eustachio areas and neighborhoods for the activities you enjoy most. Learn more about Sant'Eustachio
Via del Corso which includes heritage architecture, heritage elements and street scenes

Rome City Centre

8 out of top 10 points of interest in this area
4.5/5(3,994 area reviews)

Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago.

Find hotels in Rome City Centre

Sant'Eustachio Hotel Deals

Argentina Residenza Style Hotel

Argentina Residenza Style Hotel

4 out of 5
Via di Torre Argentina 47, Rome, RM
Fully refundableReserve now, pay when you stay
$311 nightly
The price is $360 total per night from Nov 2 to Nov 3
$360 total
Nov 2 - Nov 3
Total with taxes and fees
9.2/10 Wonderful! (1,027 reviews)
"Clean room and friendly staff"

Reviewed on Sep 29, 2025

Argentina Residenza Style Hotel
Hotel Navona

Hotel Navona

3 out of 5
Via dei Sediari 8, Rome, RM
$149 nightly
The price is $178 total per night from Nov 2 to Nov 3
$178 total
Nov 2 - Nov 3
Total with taxes and fees
8.8/10 Excellent! (996 reviews)
"Great location for walking to all of the major sites (Vatican City, Colosseum, Trevi Fountain, Spanish Steps, just minutes from Pantheon). It was terribly warm weather the week we visited and the air conditioning was wonderful! One morning we had the breakfast at the hotel - similar to continental ..."

Reviewed on Oct 1, 2025

Hotel Navona
Hotel L'Orologio Roma

Hotel L'Orologio Roma

4 out of 5
Corso Vittorio Emanuele II n. 110, Rome, RM
$327 nightly
The price is $377 total per night from Nov 3 to Nov 4
$377 total
Nov 3 - Nov 4
Total with taxes and fees
9.4/10 Exceptional! (395 reviews)
"Great staff"

Reviewed on Sep 22, 2025

Hotel L'Orologio Roma
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Discover the most popular places to visit in Sant'Eustachio

Palazzo Madama

Palazzo Madama

After visiting Palazzo Madama, make a plan to see the other sights and activities in Rome. Stroll along the riverfront or visit the notable monuments in this vibrant area.

Palazzo Madama
Sant'Ivo alla Sapienza

Sant'Ivo alla Sapienza

You can learn about the history of Rome with a stop at Sant'Ivo alla Sapienza. Discover the acclaimed art scene and stunning cathedral in this vibrant area.

Sant'Ivo alla Sapienza

Sant'Eustachio

5/5(2 reviews)

You can learn about the history of Rome when you stop by Sant'Eustachio. Stroll along the riverfront or experience the fascinating museums in this vibrant area.

Sant'Eustachio

Things to do

Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica

Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica

$40
per adult
88% of travellers recommend
Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica
Rome Hop-On Hop-Off Big Bus Tour

Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus

$34
per adult
82% of travellers recommend
Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus
Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

$35
per adult
84% of travellers recommend
Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.