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Sant'Isidoro Vacation Rentals

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Check prices for these dates

In two weeks
Dec 26 - Dec 28
In two months
Feb 6 - Feb 8
In three months
Mar 6 - Mar 8
In four months
Apr 3 - Apr 5

Our top choices for Sant'Isidoro vacation rentals

Beach nearby
AWESOME VILLA - POOL ✩ GARDEN ✩ PARKING ✩ WIFI ✩

AWESOME VILLA - POOL ✩ GARDEN ✩ PARKING ✩ WIFI ✩

AWESOME VILLA - POOL ✩ GARDEN ✩ PARKING ✩ WIFI ✩
Porto Selvaggio
10.0 out of 10, Exceptional, (1)
"We could not have been happier with the property and our hosts. Emanuele and his brother were always there when needed but let us have the privacy and freedom we needed for an amazing family holiday. The house was spacious, clean and had all the amenities we needed. Check-in was easy and we were given a lovely welcome pack comprising amazing wine, local specialities (frise) and beautiful tomatoes. Plus basil, olive oil and coffee! The pool is huge and lovely lit at night. Overall, I would...
United Kingdom
Giovanni M.
AWESOME VILLA - POOL ✩ GARDEN ✩ PARKING ✩ WIFI ✩
Suite 31 | 1 bedroom, Egyptian cotton sheets, premium bedding, down comforters
Mediterranee Suite

Mediterranee Suite

Mediterranee Suite
Lecce Historic Center
9.2 out of 10, Wonderful, (13)
"Lovely little suite, well located , a great place to stay for a short break."
United Kingdom
Michaela
$77 nightly
The price is $87
Jan 10 - Jan 11, 2026
Total with taxes and fees
Mediterranee Suite
On the beach, sun loungers
Directly on the beach. 6 beds in villa with private access to the sea

Directly on the beach. 6 beds in villa with private access to the sea

Directly on the beach. 6 beds in villa with private access to the sea
Scala di Furno
9.8 out of 10, Exceptional, (49)
"The location of this apartment is so perfect! The beach beyond the back garden is stunning and perfect for children. We had a lovely week here. Thanks Fabrizio!"
United Kingdom
Kate R.
Directly on the beach. 6 beds in villa with private access to the sea
Interior
Limehome Lecce Palazzo BN

Limehome Lecce Palazzo BN

Limehome Lecce Palazzo BN
Lecce Historic Center
7.8 out of 10, Good, (18)
"Great as always. Amazing private spaces. "
United States
Rosa
$67 nightly
The price is $74
Jan 11 - Jan 12, 2026
Total with taxes and fees
Limehome Lecce Palazzo BN
Front of property
living u HomeSuites

living u HomeSuites

living u HomeSuites
4.0 star property
Lecce
5.0 out of 10, (4)
"I did the reservation the same day that i would stay in that place. I arrived there and didnt had the acess code, so I tried do call and send messagem from the whatsapp and didnt had any awnser. I waited in the door of the propertie for more than 1 hour and didnt had any response from the owner. So I went to another hotel, and even then I didn had any response form the property owner. I request the refound of the payment!!!"
Brazil
Andrea
$73 nightly
The price is $84
Dec 18 - Dec 19
Total with taxes and fees
living u HomeSuites
Exterior
Palazzo Mosco

Palazzo Mosco

Palazzo Mosco
4.0 star property
Gallipoli Historic Center
9.0 out of 10, Wonderful, (166)
"Fantastic, very service minded and professional staff. Great breakfast and fantastic rooms."
Sweden
Maria
Palazzo Mosco
Beach nearby
LAST MINUTE DEAL - SEA FRONT PENTHOUSE GALLIPOLI SALENTO WITH 250SQM TERRACE

LAST MINUTE DEAL - SEA FRONT PENTHOUSE GALLIPOLI SALENTO WITH 250SQM TERRACE

LAST MINUTE DEAL - SEA FRONT PENTHOUSE GALLIPOLI SALENTO WITH 250SQM TERRACE
Gallipoli
9.8 out of 10, Exceptional, (76)
"Location and view from rooftop terras was beautifull."
Netherlands
Harry G.
LAST MINUTE DEAL - SEA FRONT PENTHOUSE GALLIPOLI SALENTO WITH 250SQM TERRACE
Exterior
Dimore di Lecce

Dimore di Lecce

Dimore di Lecce
Lecce Historic Center
9.4 out of 10, Exceptional, (20)
"Location great !"
Canada
Nick
$95 nightly
The price is $108
Dec 14 - Dec 15
Total with taxes and fees
Dimore di Lecce
Outdoor dining
Casa dei Mercanti Town House

Casa dei Mercanti Town House

Casa dei Mercanti Town House
Lecce Historic Center
9.6 out of 10, Exceptional, (21)
"This place was great! Near to everything and super comfortable. Our host Franzi was amazing!"
United States
Daniela
Casa dei Mercanti Town House
1 bedroom, minibar, in-room safe, desk
Hotiday Apartments Torre Lapillo

Hotiday Apartments Torre Lapillo

Hotiday Apartments Torre Lapillo
4.0 star property
Porto Cesareo
9.4 out of 10, Exceptional, (3)
"Mycket begränsat urval på frukosten. Fantastiskt läge vid stranden."
Sweden
Brita
$799 nightly
The price is $879
Dec 19 - Dec 20
Total with taxes and fees
Hotiday Apartments Torre Lapillo
1 bedroom
St. Clare House

St. Clare House

St. Clare House
Lecce Historic Center
2.0 out of 10, (1)
"Fregatura/truffa. Il gestore non si è presentato. Non c'è stato modo di contattarlo una volta arrivati lì, peccato che il pernottamento fosse già stato pagato. Così ci siamo ritrovati senza dove dormire, per fortuna Expedia ci ha coperto la prima notte in un albergo. Da sottolineare che neanche Expedia stessa sia riuscita a contattare il gestore, e che al momento non sono ancora stato rimborsato. Esperienza pessima e pessima pubblicità per Lecce. Non mi capacito come questo locale sia ancora...
Italy
Federico
St. Clare House
Standard Apartment, 1 Bedroom (Bilo 7 - 1440) | Private kitchen | Full-size fridge, cookware/dishes/utensils
Residence Kalura

Residence Kalura

Residence Kalura
Porto Cesareo
10.0 out of 10, Exceptional, (1)
Residence Kalura
Exterior
Lecce: Holiday at Salento. A vintage atmosphere in the heart of Lecce

Lecce: Holiday at Salento. A vintage atmosphere in the heart of Lecce

Lecce: Holiday at Salento. A vintage atmosphere in the heart of Lecce
Lecce Historic Center
9.8 out of 10, Exceptional, (61)
"What an amazing Italian home,,calm and relaxing in such a beautiful location,,all amenities and so clean and fresh Then go up to the roof terrace,,,HeavenlySuch fantastic hosts and so helpful in every way without being intrusive Grazie Mille "
United States
John L.
Lecce: Holiday at Salento. A vintage atmosphere in the heart of Lecce
Terrace/patio
At the sight of the Baroque

At the sight of the Baroque

At the sight of the Baroque
Lecce
9.8 out of 10, Exceptional, (7)
"Close to everything, photos of the property are accurate. Host is very accessible and accomodating."
United States
June M.
At the sight of the Baroque
Beach nearby, white sand, beach bar
Kalinifta Rooms Apartment

Kalinifta Rooms Apartment

Kalinifta Rooms Apartment
Porto Cesareo
10.0 out of 10, Exceptional, (7)
"Chloe ist eine äußerst nette und tolle Gastgeberin, für uns war alles perfekt. "
Germany
Andreas
Kalinifta Rooms Apartment
Spa
Villa Neviera - Wine Resort and Spa

Villa Neviera - Wine Resort and Spa

Villa Neviera - Wine Resort and Spa
San Donaci
10.0 out of 10, Exceptional, (1)
$87 nightly
The price is $96
Jan 7 - Jan 8, 2026
Total with taxes and fees
Villa Neviera - Wine Resort and Spa
Beach
The Villa "Riviera" large and spacious with beautiful veranda and green garden

The Villa "Riviera" large and spacious with beautiful veranda and green garden

The Villa "Riviera" large and spacious with beautiful veranda and green garden
Porto cesareo (Lecce)
8.0 out of 10, Very Good, (18)
"Fußläufig zum Strand, zweckmäßig eingerichtet, Waschmaschine und Geschirrspüler waren defekt und nicht nutzbar"
Germany
Anonymous traveler
The Villa "Riviera" large and spacious with beautiful veranda and green garden
Outdoor pool
Villa with pool, park and private pine forest, 100 meters from the sea.

Villa with pool, park and private pine forest, 100 meters from the sea.

Villa with pool, park and private pine forest, 100 meters from the sea.
MARINA DI MANCAVERSA- GALLIPOLI
9.4 out of 10, Exceptional, (30)
"Initially we were disappointed as there were only 3 bedrooms in the villa. The 4th bedroom is in the garden 50 metres from the nearest entrance to the villa with no toilet.We had a very good holiday as we visited nearby towns and villages, walked along the coast and relaxed in the beautiful garden."
United Kingdom
Dorothy W.
Villa with pool, park and private pine forest, 100 meters from the sea.
Outdoor dining
Gallipoli - Lido Pizzo - Seafront Villa - Up to 6-8 people

Gallipoli - Lido Pizzo - Seafront Villa - Up to 6-8 people

Gallipoli - Lido Pizzo - Seafront Villa - Up to 6-8 people
Gallipoli Lido Pizzo
9.4 out of 10, Exceptional, (53)
"This property was an amazing base for our time in Salento. It is close to many fabulous places to enjoy the beautiful sea. It had good outdoor space and bbq facilities - though it would have been nice to have had some ‘lounging’ chairs outdoors. The property was very clean, I felt the bed linen could have been a little newer but that’s very minor. Desiree the property manager was very welcoming and helpful and always had suggestions for where to visit, restaurants to try etc. Overall a great...
United States
Aoife S.
Gallipoli - Lido Pizzo - Seafront Villa - Up to 6-8 people
Outdoor pool
Pink Cottage. Finely furnished studio apartment with garden, patio and pool.

Pink Cottage. Finely furnished studio apartment with garden, patio and pool.

Pink Cottage. Finely furnished studio apartment with garden, patio and pool.
Porto Cesareo
9.4 out of 10, Exceptional, (11)
"We liked it alot since it matched our needs. Good combination to visit restaurants and cook you orwn food. We bought local meet and vegetable's and used the grill thats included. The pool was nice to cool down in during the hot hours, and it was cleaned once a week, the water feelt fresh to swim in. Host was easy to reach and very service minded, but we didnt have any issusses during our stay."
Sweden
Håkan S.
Pink Cottage. Finely furnished studio apartment with garden, patio and pool.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Sant'Isidoro Hotel Reviews

Victoria Palace Hotel & Zen Wellness

Victoria Palace Hotel & Zen Wellness

10/10 Excellent
"Very nice hotel and friendly staff. "
Veljko 1-night trip
Posted 12 days ago
Victoria Palace Hotel & Zen Wellness

Find out more about Sant'Isidoro

Everything you need to know about Sant'Isidoro vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Sant'Isidoro vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Sant'Isidoro vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Sant'Isidoro vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Sant'Isidoro. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Sant'Isidoro in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $74 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Sant'Isidoro rentals

At Expedia, we put the best Sant'Isidoro vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Sant'Isidoro rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Sant'Isidoro vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Sant'Isidoro. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find vacation rentals in Sant'Isidoro?

Yes, we give you a choice of vacation rentals near the most popular attractions in Sant'Isidoro, or you can go with a more remote option if you're looking for relaxation.

What are some of the best vacation rentals in Sant'Isidoro?

Kalinifta Rooms Apartment: Located near Sant'Isidoro, this vacation home rental is located on the waterfront and has a private balcony, a rooftop terrace, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities like a fridge and kitchenware can make your vacation run smoothly. You and your friends and family can relax into your vacation with amenities like a garden.

How many vacation rentals will I find in Sant'Isidoro?

Expedia has 32 vacation rentals for your stay in Sant'Isidoro.

What’s there to see and do in Sant'Isidoro?

Spiaggia di Sant'Isidoro and Ionian Sea are a couple of lovely local spots to get outside and enjoy nature. While here, Porto Selvaggio and Palude del Capitano Regional Nature Park and Lido dell' Ancora are other places worth a visit.

What’s a vacation rental in Sant'Isidoro like?

Vacation rentals are privately owned properties you can book for several days or longer in Sant'Isidoro. Vacation rentals offer amenities like kitchens and laundry facilities so your stay will be comfortable. If you're concerned about a clean environment, vacation rentals can offer a sense of seclusion away from shared hotel elevators and lobbies bustling with people while still allowing you a great travel experience. You'll also find more space in a vacation rental than in a hotel, which makes a vacation rental an attractive choice for small groups.