Find hotels near Santa Ana Port, Guayaquil from $20

Start date: Check-in selected.
To Date
End date: Check-out

  • Upfront pricing

    Our total price for your stay includes taxes and fees

  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 4 - Dec 5
Tomorrow
Dec 5 - Dec 6
This weekend
Dec 5 - Dec 7
Next weekend
Dec 12 - Dec 14

Filter by

Guest rating
Guest rating
Star rating

Compare 416 hotels close to Santa Ana Port with room rates, reviews, and availability. Most hotels are fully refundable.

Exterior
Luxva Hotel Boutique

Luxva Hotel Boutique

3.0 star property
Urdesa, 1 mi from Santa Ana Port
9.4 out of 10, Exceptional, (171)
"Breakfast was ok and the staff is wonderful!"
United States
James
$90 nightly
The price is $91
Dec 5 - Dec 6
Luxva Hotel Boutique
Exterior
Iguanazu Bed & Breakfast

Iguanazu Bed & Breakfast

3.5 star property
0.4 mi from Santa Ana Port
9.2 out of 10, Wonderful, (46)
"Excelente Todo "
Costa Rica
Cesar
$59 nightly
The price is $65
Dec 7 - Dec 8
Iguanazu Bed & Breakfast
Outdoor pool, sun loungers
Radisson Hotel Guayaquil

Radisson Hotel Guayaquil

5.0 star property
Kennedy, 1.3 mi from Santa Ana Port
9.2 out of 10, Wonderful, (630)
"Good service "
United States
Genny
$85 nightly
The price is $96
Jan 4 - Jan 5, 2026
Radisson Hotel Guayaquil
Deluxe Loft | Living area | 65-inch LCD TV with digital channels, Netflix, heated floors
PRAGA APARTMENTS

PRAGA APARTMENTS

4.0 star property
Urdesa, 0.9 mi from Santa Ana Port
9.0 out of 10, Wonderful, (15)
"Great place to stay at "
United States
Eric
PRAGA APARTMENTS
Lobby
Courtyard by Marriott Guayaquil

Courtyard by Marriott Guayaquil

3.5 star property
Kennedy, 1.5 mi from Santa Ana Port
9.0 out of 10, Wonderful, (1001)
"Great stay and they were able to accommodate our last minute booking. We had an amazing view of the city and the room was spotless."
United States
Cesar
$72 nightly
The price is $81
Dec 12 - Dec 13
Courtyard by Marriott Guayaquil
Rooftop bar, alfresco dining, open daily
Wyndham Garden Guayaquil

Wyndham Garden Guayaquil

3.5 star property
Simón Bolívar, 1.9 mi from Santa Ana Port
9.0 out of 10, Wonderful, (1001)
"Airport shuttle was very convenient "
Canada
Arlene
$68 nightly
The price is $76
Dec 6 - Dec 7
Wyndham Garden Guayaquil
Lobby
Hilton Colon Guayaquil

Hilton Colon Guayaquil

4.5 star property
Kennedy, 1.5 mi from Santa Ana Port
8.6 out of 10, Excellent, (806)
"Excellent hotel, great location, excellent food & service, the staff is well trained and are always handy for any guests needs, have shuttle service to the airport with excellent service and very attentive drivers… Would definitely recommend the hotel for any stay in Guayaquil "
United States
Monica
$94 nightly
The price is $106
Dec 13 - Dec 14
Hilton Colon Guayaquil
Outdoor pool, open 8:00 AM to 10:00 PM, sun loungers
Cedros Inn Boutique Hotel

Cedros Inn Boutique Hotel

3.5 star property
Urdesa, 1 mi from Santa Ana Port
8.4 out of 10, Very Good, (83)
"The staff went above and beyond to accommodate any special needs that we had. The place itself is clean and very beautiful. Great location, near many restaurants (and Chabad). 10/10 recommend booking your stay here. "
United States
Chana
$70 nightly
The price is $78
Dec 5 - Dec 6
Cedros Inn Boutique Hotel
Terrace/patio
Hotel Marcelius

Hotel Marcelius

3.5 star property
Kennedy, 1.4 mi from Santa Ana Port
8.2 out of 10, Very Good, (222)
"Excellent price easy to book"
United States
Carlos
$55 nightly
The price is $62
Dec 12 - Dec 13
Hotel Marcelius
Lobby sitting area
MC Suites

MC Suites

3.5 star property
Kennedy, 1.4 mi from Santa Ana Port
8.2 out of 10, Very Good, (133)
"Great place!!!!!!"
Mexico
Inti
$63 nightly
The price is $64
Dec 6 - Dec 7
MC Suites
Oven, stovetop, cookware/dishes/utensils
Pachamac House

Pachamac House

2.0 star property
1.8 mi from Santa Ana Port
$20 nightly
The price is $20
Dec 5 - Dec 6
Pachamac House
Reception
Hotel Sada

Hotel Sada

3.0 star property
2.6 mi from Santa Ana Port
9.8 out of 10, Exceptional, (7)
"El personal muy atento. "
United States
José
$42 nightly
The price is $43
Dec 5 - Dec 6
Hotel Sada
Children's activities
Oro Verde Guayaquil

Oro Verde Guayaquil

5.0 star property
Downtown Guayaquil, 2.4 mi from Santa Ana Port
9.4 out of 10, Exceptional, (1003)
"Very good stay , recommend 100%"
United States
Lenin
$85 nightly
The price is $96
Dec 7 - Dec 8
Oro Verde Guayaquil
Double Room | 1 bedroom, premium bedding, minibar, iron/ironing board
Casa Serena

Casa Serena

2.5 star property
Simón Bolívar, 2.1 mi from Santa Ana Port
9.2 out of 10, Wonderful, (54)
"the property was ok for the price"
United States
ASONG
$29 nightly
The price is $29
Dec 5 - Dec 6
Casa Serena
Executive Suite, Kitchenette, City View | Private kitchen | Microwave, electric kettle, griddle, cookware/dishes/utensils
Suitesecu Rentals Guayaquil

Suitesecu Rentals Guayaquil

4.5 star property
Simón Bolívar, 2.2 mi from Santa Ana Port
9.2 out of 10, Wonderful, (7)
"You can walk to the airport."
United States
Digna
$31 nightly
The price is $33
Dec 7 - Dec 8
Suitesecu Rentals Guayaquil
Exterior
TRYP by Wyndham Guayaquil Airport

TRYP by Wyndham Guayaquil Airport

4.5 star property
Simón Bolívar, 2.1 mi from Santa Ana Port
9.0 out of 10, Wonderful, (1000)
"Covenient, many options for dinning on premises. "
United States
MIGUEL
$85 nightly
The price is $96
Dec 5 - Dec 6
TRYP by Wyndham Guayaquil Airport
2 restaurants, breakfast, lunch, dinner served; Regional cuisine
Sheraton Guayaquil Hotel

Sheraton Guayaquil Hotel

5.0 star property
Simón Bolívar, 2 mi from Santa Ana Port
9.0 out of 10, Wonderful, (603)
"Very friendly front desk thank you for a comfortable and enjoyable stay. "
United States
Andrew
$108 nightly
The price is $121
Dec 14 - Dec 15
Sheraton Guayaquil Hotel
Terrace/patio
Harmonie

Harmonie

2.0 star property
Simón Bolívar, 2.1 mi from Santa Ana Port
9.0 out of 10, Wonderful, (80)
"Great staff very friendly Good spot"
Canada
Chelsea
$38 nightly
The price is $38
Dec 7 - Dec 8
Harmonie
Lobby
DC Suites Aeropuerto

DC Suites Aeropuerto

3.0 star property
Simón Bolívar, 2.4 mi from Santa Ana Port
9.0 out of 10, Wonderful, (578)
"Great location and clean hotel"
United States
Elvin
$34 nightly
The price is $35
Jan 1 - Jan 2, 2026
DC Suites Aeropuerto
Restaurant
Ibis Styles El Malecon Guayaquil

Ibis Styles El Malecon Guayaquil

4.0 star property
Downtown Guayaquil, 3.2 mi from Santa Ana Port
9.4 out of 10, Exceptional, (272)
"Great location and great hotel "
United States
José
$60 nightly
The price is $68
Dec 6 - Dec 7
Ibis Styles El Malecon Guayaquil
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Santa Ana Port Hotel Reviews

Hilton Colon Guayaquil

Hilton Colon Guayaquil

10/10 Excellent
"Exactly as advertised; amenities & excellent customer service. Can't wait to return."
Cynthia 4-night trip
Posted 2 days ago
Hilton Colon Guayaquil

Hotels near other Santa Ana Port attractions

Churute Mangroves Ecological Reserve

Explore the great outdoors at Churute Mangroves Ecological Reserve, a lovely green space in Guayaquil. While you're in the area, find time to visit its shops.
See properties

Alban Borja Commercial Center

During your trip to Guayaquil, you can browse for the perfect souvenirs at Alban Borja Commercial Center. While in this family-friendly area, you can savor the top-notch restaurants.
See properties

Frequently asked questions

What's the area like around Santa Ana Port?
Santa Ana Port is located in an area of Guayaquil known for its major shopping area. If you're looking for a convenient place to stay, check out the 30 hotels and other accommodations you'll find within a mile.
What's the best hotel to stay near Santa Ana Port?
Adjacent to Santa Ana Port, Apartterrazas Guayaquil is one of the top choices for your stay based on our traveler data, and this hotel offers free parking and in-room kitchenettes. Other good options within a short distance include Iguanazu Bed & Breakfast and NOVAPARK ILANES.
How many hotels are there near Santa Ana Port?
Expedia has 30 hotels and other accommodations within a mile from Santa Ana Port.
If I need to cancel the hotel reservation for my stay near Santa Ana Port, will I receive a refund?
Yes, most hotel room reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of booking. Plug in your dates, click on "Search", then filter by "fully refundable" to get top deals close to Santa Ana Port.
Where can I learn more about changing or cancelling my trip in the area near Santa Ana Port?
To find more details about picking new dates or cancelling your stay near Santa Ana Port, head over to our customer service page.
What can I see and do near Santa Ana Port?
Study the collections at Museum of Cocoa and Chocolate, Museum of Anthropology and Contemporary Art, or Nahim Isaias Museum. George Capwell Stadium, Clock Tower, and Moorish Clock Tower are some of the local landmarks to explore. You can enjoy live performances at Teatro Sanchez Aguilar and Supercines Orellana.

Explore a world of travel with Expedia