Santa Fe Vacations from $970

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Your Santa Fe Vacation

Our vacation packages to Santa Fe let you customize your own adventure. Tailor your getaway to suit your interests and needs and make the most of your time in this interesting city. Want to explore your surroundings? Alto de Piedra Waterfall, Town Square and Cerro Tute are some of the most popular places to visit during your trip to Santa Fe. Stop daydreaming and start traveling. Browse the wide range of options on Expedia today and finally put your Santa Fe vacation plans into motion!

The Latest Santa Fe vacation packages

Price found within the past 48 hours. Click for updated prices.
Las Clementinas

Las Clementinas

3.5 out of 5
Casco Viejo
Price was $1,394, price is now $970 per person
$970
per person
Jan 4 - Jan 7
found 1 day ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
9.4/10 Exceptional! (206 reviews)
Beautiful property and great restaurant! Also awesome customer service

Reviewed on Nov 7, 2026

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Price was $2,306, price is now $1,233 per person
$1,233
per person
Jan 24 - Jan 31
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
8.6/10 Excellent! (1,803 reviews)
The property is beautiful, the breakfast 9.8/10. The staff very friendly. Room was super clean! I'm already planning my trip there for next year.

Reviewed on Nov 13, 2026

Casa Lefevre By Wynwood House

Casa Lefevre By Wynwood House

3 out of 5
Casco Viejo
Price was $4,189, price is now $2,498 per person
$2,498
per person
Dec 31 - Jan 4
found 4 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9.6/10 Exceptional! (16 reviews)

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Tocumen Airport
Price was $1,727, price is now $1,126 per person
$1,126
per person
Jan 24 - Jan 31
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
8.6/10 Excellent! (1,824 reviews)
Nothing

Reviewed on Nov 13, 2026

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Bella Vista
Price was $1,721, price is now $1,163 per person
$1,163
per person
Jan 24 - Jan 31
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9/10 Wonderful! (6,099 reviews)
The Riu Plaza Hotel in Panamá City is the perfect place to stay when visiting Panamá! The convenient location, beautiful lobby, amazing breakfast buffet, comfy and quiet rooms with amazing views are hard to top. The gift shop is always fun to visit and a great place to shop for friends, family and yourself!

Reviewed on Nov 13, 2026

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Stay near popular Santa Fe attractions

Alto de Piedra Waterfall

7.6/10 (7 reviews)
Commune with nature and explore the great outdoors at Alto de Piedra Waterfall during your travels in Santa Fe. While you're in the area, wander around the natural setting.
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Santa Fe Hotel Deals

Hotel Anachoreo

Hotel Anachoreo

3 out of 5
Calle Chinita Santa Fe Veraguas Province
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $93 total per night from Nov 16 to Nov 17
$93 total
Nov 16 - Nov 17
Total with taxes and fees
9.6/10 Exceptional! (47 reviews)
"Beautiful property, great staff and delicious food!"

Reviewed on Nov 12, 2026

Hotel Anachoreo
La Qhia Eco Retreat

La Qhia Eco Retreat

2.5 out of 5
Barriada el Cerro A 100 Mts De Santa Fe Veraguas
8.2/10 Very Good! (22 reviews)
"This is a beautiful property but remember it is somewhat rustic. The neighborhood roosters make sure to wake you. The rooms are comfortable and with the mountain air and ceiling fan you don’t miss AC. Free breakfast was tasty. Dinner was good but lunch is not available. The best part is the well ..."

Reviewed on Sep 11, 2026

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La Qhia Eco Retreat
Rainforest Yasmin Hotel

Rainforest Yasmin Hotel

2.5 out of 5
Veraguas Santa Fe Provincia de Veraguas
Get rates
Rainforest Yasmin Hotel
See all 15 properties in Santa Fe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Fe Vacation Packages

Santa Fe Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Population
970
Max Temp Winter
90ºF
Max Temp Summer
85ºF
Top Sights
Alto de Piedra Waterfall, Cascada de Bermejo and Town Square

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Frequently asked questions

How much does a Santa Fe vacation package cost?
You'll find cheap prices from $970 on Expedia for your Santa Fe break. However, factors like the season, length of stay and your choice of hotel will determine how much your vacation to Santa Fe costs.
What are the cheapest months to go to Santa Fe?
If you're looking to score a cheap Santa Fe vacation package, consider traveling in April, July and August. You'll generally find lower prices on airfares and hotels during these quieter months — perfect for a budget-friendly break.
How many days is enough for Santa Fe?
Typically, a handful of days is enough to check out the main attractions during your Santa Fe vacation. But if you'd like to have some time to rest or go on day trips, think about extending your itinerary.
Is it worth booking a vacation package to Santa Fe?
Well known for its nature, hiking and a host of other highlights, you can be certain Santa Fe is a good vacation destination. Some of the top attractions to put on your to-do list? Don't miss Alto de Piedra Waterfall and Town Square during your Santa Fe vacation.
How to find the best Santa Fe package deals?
Start your search for a Santa Fe package deal by entering your preferred travel dates and destination under our "Packages" tab. Then add some filters, like "Property type" and "Amenities," to tailor the results to your exact needs. You can also sort by "Package discount" and browse offers that come with big savings. If you don't find the perfect Santa Fe package deal straight away, just play around with your dates and search again. Remember that deals are only available for a limited time, so book early and get your Santa Fe getaway off to a flying start.
Is it cheaper to book a Santa Fe vacation as a package?
Expedia vacation packages are designed to help you keep more money in your pocket. Bundle your flight, car rental and hotel into one great-value price and you could save hundreds of dollars. You'll generally land a better deal than booking each component individually. And you'll still get the flexibility to create a personalized Santa Fe vacation by choosing your favorite accommodation type, airline and car class.
When to book a vacation package to Santa Fe?
Enjoy incredible discounts by reserving your flights early with Expedia. If being spontaneous is more your thing, grab one of our last-minute deals for an impromptu Santa Fe trip.
Does Expedia offer Book Now, Pay Later Santa Fe vacation packages?
Secure your ideal getaway to Santa Fe with Expedia's Book Now, Pay Later vacations. There's no need to scrimp and save or wait for your next paycheck — we've partnered with online lender Affirm to give you more flexibility and choice. Our vacation packages with payment plans let you spread the total cost over 3, 6 or 12 months. With no hidden or late payment fees, it's a breeze to stick to your budget and snap up bargains before they disappear.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.