Title: Santa Fe Vacation Packages 2026 from $666 | Expedia.com [Santa Fe Travel Guide](https://expedia.com/Santa-Fe.dx6224616)[Hotels in Santa Fe](https://expedia.com/Santa-Fe-Hotels.d6224616.Travel-Guide-Hotels)[Vacation Rentals in Santa Fe](https://expedia.com/Santa-Fe-Vacation-Rentals.d6224616.Travel-Guide-VacationRentals)[Flights to Santa Fe](https://expedia.com/Cheap-Flights-To-Santa-Fe.d6224616.Travel-Guide-Flights)[Car Rentals in Santa Fe](https://expedia.com/Car-Rentals-In-Santa-Fe.d6224616.Car-Rental-Guide) ![](https://images.trvl-media.com/place/6224616/df969f8c-67fa-4e06-9a3c-36132a6e1b9b.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Santa Fe Vacations from $666 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Your Santa Fe Vacation Our vacation packages to Santa Fe let you customize your own adventure. Tailor your getaway to suit your interests and needs and make the most of your time in this interesting city. Want to explore your surroundings? [Alto de Piedra Waterfall](https://www.expedia.com/Alto-De-Piedra-Waterfall-Santa-Fe.d553248621532965236.Vacation-Attraction), [Town Square](https://www.expedia.com/Town-Square-Santa-Fe.d6224711.Vacation-Attraction) and [Cerro Tute](https://www.expedia.com/Cerro-Tute-Santa-Fe.d553248621532965233.Vacation-Attraction) are some of the most popular places to visit during your trip to Santa Fe. Stop daydreaming and start traveling. Browse the wide range of options on Expedia today and finally put your Santa Fe vacation plans into motion! ## The Latest Santa Fe vacation packages Price found within the past 48 hours. Click for updated prices. ![Villa Botero By Casa Mojito B&B](https://images.trvl-media.com/lodging/12000000/11930000/11927200/11927153/393d35f8_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Villa Botero By Casa Mojito B&B Save 100% on your flight $666 per person May 4 - May 11 found 1 day ago Roundtrip flight included Miami (MIA) to Panama City (PTY) 9.8/10 Exceptional! (60 reviews) We stayed one night and it exceeded our expectations. The owners were incredibly friendly and easy to contact, making us feel right at home. Everything was spotless, and the atmosphere was warm and inviting. The homemade breakfast was a highlight—absolutely delicious and full of flavor. We will stay again longer next time. Reviewed on Jan 22, 2026 ![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Central Hotel Panama Casco Viejo Casco Viejo Save 100% on your flight $1,159 per person May 17 - May 23 found 1 day ago Roundtrip flight included Atlanta (ATL) to Panama City (PTY) 9/10 Wonderful! (1,002 reviews) Room was amazing, beautiful hotel in the center of town. Service also very good and attentive. Amazing breakfast. Reviewed on Feb 24, 2026 ![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Megapolis Hotel Panamá San Francisco Save 100% on your flight $1,108 per person May 17 - May 23 found 1 day ago Roundtrip flight included Atlanta (ATL) to Panama City (PTY) 8.4/10 Very Good! (1,204 reviews) No complaints excellent Reviewed on Feb 26, 2026 ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Riu Plaza Panama Bella Vista $819 per person May 17 - May 23 found 1 day ago Roundtrip flight included Atlanta (ATL) to Panama City (PTY) 9/10 Wonderful! (4,515 reviews) The amenities were great! The food at the buffet wasnt all thay great tho. Also, tje menu was the same at each restaurant. The quality wasnt great.bthe rooms were clean and the staff was frie Reviewed on Mar 2, 2026 ![Hyatt Regency Panama City](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/w3837h2557x3y3-241f7e7d_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hyatt Regency Panama City Bella Vista $944 per person May 17 - May 23 found 1 day ago Roundtrip flight included Atlanta (ATL) to Panama City (PTY) 10/10 Exceptional! (103 reviews) Great hotel. Very clean, nice breakfast, free valet parking. Reviewed on Mar 1, 2026 Don't see what you're looking for? See all available trips from Columbus to Santa Fe [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-04-02/2026-04-09/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=PAC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=PKG_SPRING_PROMO_6224616) ### Discover the most popular places to visit in Santa Fe #### Quebrada Las Trancas Spa Commune with nature and explore the great outdoors at Quebrada Las Trancas Spa during your travels in Santa Fe. While you're in the area, wander around the natural setting. [](https://expedia.com/Quebrada-Las-Trancas-Spa-Santa-Fe.d553248635976022318.Vacation-Attraction) #### Alto de Piedra Waterfall Commune with nature and explore the great outdoors at Alto de Piedra Waterfall during your travels in Santa Fe. While you're in the area, wander around the natural setting. [](https://expedia.com/Alto-De-Piedra-Waterfall-Santa-Fe.d553248621532965236.Vacation-Attraction) #### Orchid House Explore the great outdoors at Orchid House, a lovely green space in Santa Fe. Stroll along the riverfront or visit the churches while you're in the area. [](https://expedia.com/Orchid-House-Santa-Fe.d6224705.Vacation-Attraction) ## Santa Fe Hotel Deals ![La Qhia Eco Retreat](https://images.trvl-media.com/lodging/30000000/29440000/29430100/29430099/efe9a595_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### La Qhia Eco Retreat Barriada el Cerro A 100 Mts De Santa Fe Veraguas [Get rates](https://expedia.com/Hotel-Search?startDate=3%2F16%2F2026&endDate=3%2F17%2F2026&selected=29430099&PinnedHotelID=29430099&HadPinnedHotel=true®ionId=6224616) [](https://expedia.com/Hotel-Search?startDate=3%2F16%2F2026&endDate=3%2F17%2F2026&selected=29430099&PinnedHotelID=29430099&HadPinnedHotel=true®ionId=6224616) ![Hotel Anachoreo](https://images.trvl-media.com/lodging/28000000/27780000/27775700/27775675/32d16900_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Anachoreo Calle Chinita Santa Fe Veraguas Province Fully refundableReserve now, pay when you stay 9.6/10 Exceptional! (39 reviews) Nice room, comfortable. A/C. The grounds were beautifully landscaped and had many options for spending time outdoors sitting, talking, working, napping, watching wild birds, or eating at the al fresco restaurant. The staff worked hard to make our stay enjoyable. Volcancito’s weather was drier and ... Reviewed on Feb 25, 2026 [Get rates](https://expedia.com/Hotel-Search?startDate=3%2F16%2F2026&endDate=3%2F17%2F2026&selected=27775675&PinnedHotelID=27775675&HadPinnedHotel=true®ionId=6224616) [](https://expedia.com/Hotel-Search?startDate=3%2F16%2F2026&endDate=3%2F17%2F2026&selected=27775675&PinnedHotelID=27775675&HadPinnedHotel=true®ionId=6224616) ![Cabana Vergara Santa Fe](https://images.trvl-media.com/lodging/109000000/108020000/108011300/108011213/w1440h1075x0y422-dda3f8cf_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Cabana Vergara Santa Fe Provincia de Veraguas, Panama Panama $160 nightly $160 total Mar 3 - Mar 4 Total with taxes and fees [](https://expedia.com/Hotel-Search?startDate=3%2F3%2F2026&endDate=3%2F4%2F2026&selected=108011213&PinnedHotelID=108011213&HadPinnedHotel=true®ionId=6224616) [See all 15 properties in Santa Fe](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=3%2F3%2F2026&endDate=3%2F4%2F2026®ionId=6224616) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Find the Best Santa Fe Vacation Packages ## Santa Fe Essential Information | Language | Spanish | | --------------- | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Currency | Panamanian balboas | | Local Welcome | ¡Hola! | | Local Goodbye | Adiós | | Population | 970 | | Max Temp Winter | 90ºF | | Max Temp Summer | 85ºF | | Top Sights | [Alto de Piedra Waterfall](https://www.expedia.com/Alto-De-Piedra-Waterfall-Santa-Fe.d553248621532965236.Vacation-Attraction), [Cascada de Bermejo](https://www.expedia.com/Cascada-De-Bermejo-Santa-Fe.d553248621532965237.Vacation-Attraction) and [Town Square](https://www.expedia.com/Town-Square-Santa-Fe.d6224711.Vacation-Attraction) | ## 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[](https://expedia.com/lp/theme-vacations/cheap-vacations?rfrr=editorial.Cheap_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/06/26/1175883311.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Solo Vacations [](https://expedia.com/lp/b/vacations/solo-vacations?rfrr=editorial.Solo_Vacations.click) ## Frequently asked questions ### How much does a Santa Fe vacation package cost? ### What are the cheapest months to go to Santa Fe? ### How many days is enough for Santa Fe? ### Is it worth booking a vacation package to Santa Fe? ### How to find the best Santa Fe package deals? ### Is it cheaper to book a Santa Fe vacation as a package? ### When to book a vacation package to Santa Fe? ### Does Expedia offer Book Now, Pay Later Santa Fe vacation packages? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - [Hotels near Catholic Church of Santa Fe ](https://www.expedia.com/Catholic-Church-Of-Santa-Fe-Hotels.0-l6224700-0.Travel-Guide-Filter-Hotels) - [Hotels near Town Square ](https://www.expedia.com/Town-Square-Hotels.0-l6224711-0.Travel-Guide-Filter-Hotels) - [Hotels near Alto de Piedra Waterfall ](https://www.expedia.com/Alto-De-Piedra-Waterfall-Hotels.0-l553248621532965236-0.Travel-Guide-Filter-Hotels) - [Hotels near Orchid House ](https://www.expedia.com/Orchid-House-Hotels.0-l6224705-0.Travel-Guide-Filter-Hotels) - [Hotels near Cerro Tute ](https://www.expedia.com/Cerro-Tute-Hotels.0-l553248621532965233-0.Travel-Guide-Filter-Hotels) - [Hotels near Quebrada Bulava ](https://www.expedia.com/Quebrada-Bulava-Hotels.0-l553248621532965235-0.Travel-Guide-Filter-Hotels) - [Hotels near Cascada de Bermejo ](https://www.expedia.com/Cascada-De-Bermejo-Hotels.0-l553248621532965237-0.Travel-Guide-Filter-Hotels) - [Flights to El Alto ](https://www.expedia.com/Cheap-Flights-To-El-Alto.d829297084000657408.Travel-Guide-Flights) - [Flights to El Cuay ](https://www.expedia.com/Cheap-Flights-To-El-Cuay.d829297080754270208.Travel-Guide-Flights) - [Catholic Church of Santa Fe ](https://www.expedia.com/Catholic-Church-Of-Santa-Fe-Santa-Fe.d6224700.Vacation-Attraction) - [Town Square ](https://www.expedia.com/Town-Square-Santa-Fe.d6224711.Vacation-Attraction) - [Cascada de Bermejo ](https://www.expedia.com/Cascada-De-Bermejo-Santa-Fe.d553248621532965237.Vacation-Attraction) - [Cerro Tute ](https://www.expedia.com/Cerro-Tute-Santa-Fe.d553248621532965233.Vacation-Attraction) - [Orchid House ](https://www.expedia.com/Orchid-House-Santa-Fe.d6224705.Vacation-Attraction) - [Quebrada Las Trancas Spa ](https://www.expedia.com/Quebrada-Las-Trancas-Spa-Santa-Fe.d553248635976022318.Vacation-Attraction) - [Alto de Piedra Waterfall ](https://www.expedia.com/Alto-De-Piedra-Waterfall-Santa-Fe.d553248621532965236.Vacation-Attraction) - [Car rentals near Catholic Church of Santa Fe ](https://www.expedia.com/Car-Rentals-In-Catholic-Church-Of-Santa-Fe.d6224700.Car-Rental-Guide) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app