Santa Maria Vacations from $758

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The Latest Santa Maria vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Casa Zañartu

Hotel Casa Zañartu

4 out of 5
Downtown Santiago
Price was $932, price is now $758 per person
$758
per person
May 21 - May 28
found 5 hours ago
Roundtrip non-stop flight included
Guatemala City (GUA) to Santiago (SCL)
8.6/10 Excellent! (292 reviews)
The hotel is well located and is in a safe area The room was not overly large and is a bit dated. Some noise does come up from the internal cafe downstairs with loud talking and furniture. The staff are very friendly and helpful. A number of restaurants nearby.

Reviewed on Apr 11, 2026

Hotel Boutique Castillo Rojo

Hotel Boutique Castillo Rojo

4 out of 5
Bellavista
Price was $1,032, price is now $799 per person
$799
per person
May 21 - May 28
found 5 hours ago
Roundtrip non-stop flight included
Guatemala City (GUA) to Santiago (SCL)
9.6/10 Exceptional! (715 reviews)
Lovely boutique hotel in a great neighborhood! Our room was spotless, we had a bottle of sparkling white as a welcome, breakfast was fresh and delish. The atmosphere of the Castillo Rojo is just charming! Happy hour every day on the patio...just wonderful! The staff could not have been any better! We LOVED our stay at the Castillo Rojo and loved our stay in Santiago!

Reviewed on Apr 14, 2026

Matildas Hotel Boutique

Matildas Hotel Boutique

3.5 out of 5
Downtown Santiago
Price was $1,099, price is now $896 per person
$896
per person
May 21 - May 28
found 5 hours ago
Roundtrip non-stop flight included
Guatemala City (GUA) to Santiago (SCL)
9.4/10 Exceptional! (281 reviews)
The staff were professional, Love the place ( quiet, very clean, breakfast).

Reviewed on Apr 13, 2026

ICON Hotel

ICON Hotel

4 out of 5
Las Condes
Price was $1,638, price is now $1,055 per person
$1,055
per person
Jun 27 - Jul 3
found 1 day ago
Roundtrip non-stop flight included
Miami (MIA) to Santiago (SCL)
8.6/10 Excellent! (1,004 reviews)
Our stay was good, with quick check-in and check-out. The breakfast was very good, and the service was excellent. The only thing to improve is that the bathroom towels were very old and dark, some even had loose threads.

Reviewed on Apr 12, 2026

Hotel Capital Bellet

Hotel Capital Bellet

3 out of 5
Providencia
Price was $1,304, price is now $950 per person
$950
per person
Jun 27 - Jul 3
found 1 day ago
Roundtrip non-stop flight included
Miami (MIA) to Santiago (SCL)
9/10 Wonderful! (1,007 reviews)
they clean the room every day. They cleaned the bathroom. It’s great. Staff is nice. Breakfast is good. Would be nice if they mix it up instead of having exactly the same things every day. No gym. Not a lot of seating space in the lobby as you wait for the flight after a checkout.

Reviewed on Apr 13, 2026

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Discover the most popular places to visit in Santa Maria

El Zaino Dreaming Stones

You can find out about the history of Santa Maria with a stop at El Zaino Dreaming Stones.

El Zaino Dreaming Stones

What to do in Santa Maria

Tour 1 Day Portillo and Lagoon of the Inca from Santiago Picnic

Tour 1 Day Portillo and Lagoon of the Inca from Santiago Picnic

$75
per adult
Tour 1 Day Portillo and Lagoon of the Inca from Santiago Picnic
See all activities in Santa Maria

Santa Maria Hotel Deals

Termas Jahuel Hotel & Spa

Termas Jahuel Hotel & Spa

3.5 out of 5
Jahuel s/n - San Felipe Santa Maria Valparaiso
8.4/10 Very Good! (10 reviews)
Estadía de Lujo
Excelente servicio, maravilloso lugar para desconectarse de la ciudad, los tratamientos del spa realmente espectaculares, la comida buenísima, realmente un servicio de lujo.

Reviewed on Mar 31, 2021

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Termas Jahuel Hotel & Spa
Enjoy Santiago - Hotel del Valle

Enjoy Santiago - Hotel del Valle

4.5 out of 5
Los Libertadores Km 53 Rinconada Valparaiso
Fully refundableReserve now, pay when you stay
$126 nightly
The price is $126 total per night from May 12 to May 13
$126 total
May 12 - May 13
8.6/10 Excellent! (164 reviews)
We stayed here one night on our way north. The staff were friendly and professional. The room was huge and the bathroom had a separate shower and stand alone tub. Great for a romatic night or some TLC while sipping wine and reading your favourite novel. The hotel and the rooms are a bit tired and ...

Reviewed on Feb 8, 2026

Enjoy Santiago - Hotel del Valle
Hotel Genova

Hotel Genova

2.5 out of 5
523 Las Heras Los Andes Región de Valparaíso
Fully refundableReserve now, pay when you stay
$40 nightly
The price is $40 total per night from May 1 to May 2
$40 total
May 1 - May 2
Hotel Genova
See all 25 properties in Santa Maria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Maria Vacation Packages

Santa Maria Essential Information

Language
Spanish
Currency
Chilean pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Max Temp Winter
50ºF
Max Temp Summer
75ºF
Top Sights
Vina Errazuriz and Vina Von Siebenthal

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Frequently asked questions

How much does a Santa Maria vacation package cost?
You can snap up a vacation package to this destination from $758 on Expedia. But how much your vacation to Santa Maria costs will depend on factors like the season, hotel choice and length of stay.
What are the cheapest months to go to Santa Maria?
December, January and February are the best times to search for cheap Santa Maria vacation packages. Traveling in quieter periods means you'll typically find reduced prices on flights and hotels.
How many days is enough for Santa Maria?
Usually, a handful of days is enough to see the major attractions during your Santa Maria vacation. However, if you prefer to have some time to chill out or go on day trips, think about extending your itinerary.
How to find the best Santa Maria package deals?
Start your search for a Santa Maria package deal by entering your preferred trip dates and destination under our "Packages" tab. Then apply a few filters, like "Popular locations" and "Property type," to tailor the results to your exact style. You can also sort by "Package discount" and browse offers that come with huge savings. If you don't find the perfect Santa Maria package deal right away, just tweak your dates and search again. Remember that deals are only available for a limited time, so book early and get your Santa Maria escape off to a flying start.
Is it cheaper to book a Santa Maria vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your flight, car rental and hotel into one great-value price and you could save hundreds of dollars. You'll usually snag a better deal than booking each component individually. And you'll still enjoy the flexibility to create a personalized Santa Maria vacation by choosing your preferred accommodation type, airline and car class.
When to book a vacation package to Santa Maria?
If you have your Santa Maria vacation dates confirmed, book early to snap up some terrific deals. With Expedia, you can often reserve some flights up to one year ahead of time. Prefer spur-of-the-moment adventures? Our last-minute deals are perfect for quick escapes.
How to plan a trip to Santa Maria?

  1. Choose when to go: Check your diary and get packing. Your favorite season and the activities on offer will also help you decide when to visit Santa Maria.
  2. Work out your budget: Ensure you have enough money to cover everything from meals and transportation to flights and activities. Your accommodations will probably be the biggest expense during your trip to Santa Maria.
  3. Use our trip planning tool to discover Santa Maria: Research every part of your trip to Santa Maria with this comprehensive planner. Invite your family and friends to collaborate on a group getaway, search for stays or things to do and make bookings.
  4. Set the duration of your trip: Start by compiling a list of the attractions and activities you want to get to in Santa Maria. Then, estimate how long you'll need at each, including any travel time.
  5. Bundle your bookings: With your travel dates in order, you can combine your car rental, flights, hotels and more into a customized Santa Maria vacation package.
  6. Book any excursions or activities: Now to the fun part — locking in everything you want to do and see. Browse some of the exciting things to do in Santa Maria and book your tickets early to save time (and maybe some cash too!).

Does Expedia offer Book Now, Pay Later Santa Maria vacation packages?
Your Santa Maria break should be a relaxing escape from your busy life, not a reason for money worries. So to give you a little more flexibility, we've partnered with online lender Affirm to bring you our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and break down the cost over 3, 6 or 12 months. Plus, there aren't any hidden or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.