La Reina

Santiago

A market stall with various vegetables and fruits, including onions, garlic, and tomatoes, with price tags visible.
A market stall with various vegetables like carrots, cucumbers, and leafy greens.
A residential street with parked cars, trees, and mountains in the background.

Stay near popular La Reina attractions

Vertigo Park

You can take time to visit Vertigo Park during your travels to Santiago. Experience the area's jazz scene and live music.
See properties

Things to do

Santiago: Concha y Toro and Undurraga Vineyards Tour

Santiago: Concha y Toro and Undurraga Vineyards Tour

$76
per adult
100% of travellers recommend
Santiago: Concha y Toro and Undurraga Vineyards Tour
Santiago: Portillo and Laguna del Inca Day Trip with Picnic

Santiago: Portillo and Laguna del Inca Day Trip with Picnic

$54
per adult
Santiago: Portillo and Laguna del Inca Day Trip with Picnic
Discover Santiago: Tourist Bus, Cerro San Cristobal and Wine

Discover Santiago: Tourist Bus, Cerro San Cristobal and Wine

$115
per adult
100% of travellers recommend
Discover Santiago: Tourist Bus, Cerro San Cristobal and Wine
From Santiago: Rafting in the Maipo Canyon

From Santiago: Rafting in the Maipo Canyon

$35
per adult
From Santiago: Rafting in the Maipo Canyon
Santiago: The Essentials City Tour & Optional Concha y Toro

Santiago: The Essentials City Tour & Optional Concha y Toro

$49
per adult
90% of travellers recommend
Santiago: The Essentials City Tour & Optional Concha y Toro
Santiago: Valparaiso + Viña del Mar – Classic Guided Tour: Cultural Heritage

Santiago: Valparaiso + Viña del Mar Classic Guided Sightseeing Tour - Cultural Heritage

$33
per adult
Santiago: Valparaiso + Viña del Mar Classic Guided Sightseeing Tour - Cultural Heritage
See all activities in Santiago

La Reina Hotel Deals

Holiday Inn Santiago - Airport Terminal by IHG

Holiday Inn Santiago - Airport Terminal by IHG

4 out of 5
Armando Cortinez Norte 2150 Santiago Region Metropolitana
$162 nightly
The price is $162 total per night from Aug 28 to Aug 29
$162 total
Aug 28 - Aug 29
Book a stay at this ski hotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the restaurant and the helpful staff in ...
9/10 Wonderful! (1,528 reviews)
"Excellent resto"

Reviewed on Aug 1, 2026

Holiday Inn Santiago - Airport Terminal by IHG
Mandarin Oriental, Santiago

Mandarin Oriental, Santiago

5 out of 5
Kennedy Avenue #4601 Santiago Region Metropolitana
$207 nightly
The price is $207 total per night from Aug 14 to Aug 15
$207 total
Aug 14 - Aug 15
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the property condition ...
9.2/10 Wonderful! (1,002 reviews)
"We appreciate the staff giving us the service and consideration to later check out for 6pm flight."

Reviewed on Jul 21, 2026

Mandarin Oriental, Santiago
City Express by Marriott Santiago Aeropuerto Chile

City Express by Marriott Santiago Aeropuerto Chile

3 out of 5
Av. Américo Vespucio Oriente 1295 Santiago
$85 nightly
The price is $85 total per night from Aug 15 to Aug 16
$85 total
Aug 15 - Aug 16
Book a stay at this business-friendly hotel in Santiago. Enjoy free breakfast, a free airport shuttle, and 24-hour room service. Our guests praise the breakfast ...
8.8/10 Excellent! (1,004 reviews)
"I have never written a negative feedback. This situation was different. I landed in Santiago at 9am with 17 hour unexpected layover time and I wanted to find a place to sleep. I found this hotel and called them from the airport asking if they have a room to check me in and I was going to leave later ..."

Reviewed on Aug 2, 2026

City Express by Marriott Santiago Aeropuerto Chile
Wyndham Santiago Aeropuerto

Wyndham Santiago Aeropuerto

4.5 out of 5
Av. Americo Vespucio 1284 Santiago Santiago
$98 nightly
The price is $98 total per night from Aug 30 to Aug 31
$98 total
Aug 30 - Aug 31
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the clean rooms ...
9/10 Wonderful! (1,384 reviews)
"Specifically booked for the airport shuttle included, they messaged only right before my stay to specify the shuttle had luggage size requirements, I was already on my trip as this is an airport hotel, so obviously people will only be there for a very short period of time… like a single night… the ..."

Reviewed on Aug 2, 2026

Wyndham Santiago Aeropuerto
Hotel Plaza San Francisco

Hotel Plaza San Francisco

4 out of 5
Alameda 816 Santiago Region Metropolitana
$114 nightly
The price is $114 total per night from Sep 2 to Sep 3
$114 total
Sep 2 - Sep 3
Book a stay at this spa hotel in Santiago. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the bar in our reviews. ...
9.2/10 Wonderful! (1,003 reviews)
"We had a great one night stay. Everything was clean and comfortable and the rooms are very spacious and take you back in time. The staff were very attentive and helpful and the wonderful breakfast was a fantastic way to start the day. They even cater especially to kids with an activity chest. It ..."

Reviewed on Aug 2, 2026

Hotel Plaza San Francisco
The Singular Santiago

The Singular Santiago

5 out of 5
Merced 294 Santiago Region Metropolitana
$270 nightly
The price is $270 total per night from Aug 9 to Aug 10
$270 total
Aug 9 - Aug 10
Book a stay at this luxury hotel in Santiago. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the bar and the helpful staff in our reviews. ...
The Singular Santiago
See all 2,674 properties in La Reina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in La Reina

Find the best La Reina areas and neighborhoods for the activities you enjoy most. Learn more about La Reina
Learn more about La Reina
A cityscape with a prominent skyscraper and snow-covered mountains in the background.
Photo by Maria Isabel
Open Photo by Maria Isabel

Providencia

Noted for its cafes and shopping, there's plenty to explore in Providencia. Top attractions like Costanera Center and Gran Torre Santiago are major draws, and you can hop on the metro at Pedro de Valdivia Station or Los Leones Station to see more of the city.

A city park with a fountain, trees, and modern buildings in the background.

Las Condes

Cafes, shopping, and mountain views highlight some notable features of Las Condes. Make a stop by Alto Las Condes or KidZania Santiago while you're visiting, and jump aboard the metro at Hernando de Magallanes Station or Manquehue Station to get around town.

A historic building with a fountain, surrounded by lush greenery and a clear blue pool.

Downtown Santiago

Noted for its museums and art galleries, there's plenty to explore in Downtown Santiago. Top attractions like Fantasilandia and Palacio de la Moneda are major draws, and you can hop on the metro at Toesca Station or O'Higgins Park Station to see more of the city.

A city street with modern buildings, a clear sky, and a few cars.

Vitacura

Vitacura is popular for its abundant dining options, and if you're looking for more to see and do, you might think about a trip to Casacostanera or Santiago Metropolitan Park.

A historic building with a yellow facade, palm trees, and a staircase leading up to it.

Lastarria

Lastarria is known for its ample dining options, and you can make a stop by Lastarria District and Gabriela Mistral Cultural Center while in the area.

La Reina

Choose one or more items to build your trip:

Explore a world of travel with Expedia