An aerial view of a town with industrial buildings, roads, and green areas.

St. Charles Vacation Rentals

Check prices for these dates

In two weeks
Oct 9 - Oct 11
In two months
Nov 20 - Nov 22
In three months
Dec 18 - Dec 20
In four months
Jan 15 - Jan 17

Our top choices for St. Charles vacation rentals

A wooden cabin with a porch, two chairs, and a door.

1. Tiny Treehouse Cabin | Bluff Woodlands #2

Tiny Treehouse Cabin | Bluff Woodlands #2
Elba
9.8 out of 10, Exceptional, (17 reviews)
"Beautiful area enjoyed our stay immensely"
United Kingdom
I.M l.
$171 nightly
The price is $184
Sep 24 - Sep 25
Total with taxes and fees
Tiny Treehouse Cabin | Bluff Woodlands #2
A covered deck with outdoor seating, surrounded by a forested area.

2. Tiny Treehouse Cabin | Bluff Woodlands #3

Tiny Treehouse Cabin | Bluff Woodlands #3
Elba
10.0 out of 10, Exceptional, (13 reviews)
"My family of 4 had a wonderful stay!"
United States
Josh S.
$183 nightly
The price is $196
Sep 24 - Sep 25
Total with taxes and fees
Tiny Treehouse Cabin | Bluff Woodlands #3
Two wooden cabins elevated on stilts in a forest, with outdoor seating and hammocks.

3. Tiny Treehouse Cabin | Bluff Woodlands #1

Tiny Treehouse Cabin | Bluff Woodlands #1
Elba
9.6 out of 10, Exceptional, (10 reviews)
"Great area a place to stay. "
United States
Paul T.
$183 nightly
The price is $196
Sep 24 - Sep 25
Total with taxes and fees
Tiny Treehouse Cabin | Bluff Woodlands #1
A wooden cabin with a porch, two chairs, and a door.

4. Three Treehouse Cabins in the Bluff Woodlands

Three Treehouse Cabins in the Bluff Woodlands
Elba
$498 nightly
The price is $536
Sep 24 - Sep 25
Total with taxes and fees
Three Treehouse Cabins in the Bluff Woodlands
A living room with a television, sofa, coffee table, and shelves with decorative items.

5. Vintage Lustron Home Piece of History

Vintage Lustron Home Piece of History
Minnesota City
10.0 out of 10, Exceptional, (36 reviews)
"A beautiful comfortable welcoming home!"
United States
Jocelyn R.
$199 nightly
The price is $214
Oct 4 - Oct 5
Total with taxes and fees
Vintage Lustron Home Piece of History
An RV interior with a kitchen, seating area, and a view of the outside.

6. Big River Escape Bear Camper #2

Big River Escape Bear Camper #2
Buffalo City
10.0 out of 10, Exceptional, (1 review)
"We have stayed there a few times & it was great for us! This is the first time in a camper and it was very cute and clean! So recommend!"
United States
Marcy P.
$138 nightly
The price is $146
Sep 24 - Sep 25
Total with taxes and fees
Big River Escape Bear Camper #2
A two-story house with a covered patio and a pathway leading to the entrance.

7. Magical Nest Hideaway

Magical Nest Hideaway
Rochester
10.0 out of 10, Exceptional, (165 reviews)
"An excellent place to stay! Clean, private, safe and beautiful neighborhood. "
United States
Brandi B.
$150 nightly
The price is $173
Sep 25 - Sep 26
Total with taxes and fees
Magical Nest Hideaway
A rustic wooden pavilion with picnic tables, surrounded by a gravel area and grassy lawn.

8. Cozy River Cabin w/ Loft & Screened Porch

Cozy River Cabin w/ Loft & Screened Porch
Buffalo City
10.0 out of 10, Exceptional, (2 reviews)
"It was a in and out stay. Would have liked to been able to check in earlier since we came from a distance and woulda been nice to have a place to change church clothes without a fee. Other than that all worked out."
United States
John S.
$148 nightly
The price is $156
Sep 27 - Sep 28
Total with taxes and fees
Cozy River Cabin w/ Loft & Screened Porch
A dining room with a white table, white chairs, a chandelier, and a potted plant.

9. Discounted Charming 2-bedroom main-level TRIPLEX in Rochester

Discounted Charming 2-bedroom main-level TRIPLEX in Rochester
East Side Pioneers
9.4 out of 10, Exceptional, (22 reviews)
"The place was great"
United States
Michelle L.
$190 nightly
The price is $218
Sep 29 - Sep 30
Total with taxes and fees
Discounted Charming 2-bedroom main-level TRIPLEX in Rochester

10. UrbanCottage | 1mi Mayo Clinic, No Stairs, Dogs OK

UrbanCottage | 1mi Mayo Clinic, No Stairs, Dogs OK
East Side Pioneers
$158 nightly
The price is $181
Sep 27 - Sep 28
Total with taxes and fees
UrbanCottage | 1mi Mayo Clinic, No Stairs, Dogs OK
A living room with a flat-screen TV on a wooden stand, a gray sofa, and a blue armchair.

11. Close to Mayo/Shops, 1 step entry Covered By Faith

Close to Mayo/Shops, 1 step entry Covered By Faith
Rochester
9.8 out of 10, Exceptional, (13 reviews)
"The host was so incredibly responsive whenever we had questions, the house was incredibly clean and welcoming, and we enjoyed our stay there."
United States
Anonymous traveler
$259 nightly
The price is $298
Oct 1 - Oct 2
Total with taxes and fees
Close to Mayo/Shops, 1 step entry Covered By Faith
A two-story house with a wooden staircase leading to a yellow door, a brick wall, and a window with a white frame.

12. Charming 1BR house with WiFi, AC, Private Patio + Cruiser Bikes & Grill Add-Ons

Charming 1BR house with WiFi, AC, Private Patio + Cruiser Bikes & Grill Add-Ons
Historic Downtown Winona
10.0 out of 10, Exceptional, (32 reviews)
$171 nightly
The price is $190
Sep 28 - Sep 29
Total with taxes and fees
Charming 1BR house with WiFi, AC, Private Patio + Cruiser Bikes & Grill Add-Ons
A modern kitchen with a central island, bar stools, and a view of the backyard through large sliding doors.

13. Meet Don - A Modern, Zero-step, Pet-friendly home in Rochester

Meet Don - A Modern, Zero-step, Pet-friendly home in Rochester
Slatterly Park
10.0 out of 10, Exceptional, (40 reviews)
"Great host, great property!"
United States
Ashley T.
$217 nightly
The price is $250
Sep 24 - Sep 25
Total with taxes and fees
Meet Don - A Modern, Zero-step, Pet-friendly home in Rochester

14. Riverfront Cabin with Private Dock

Riverfront Cabin with Private Dock
Buffalo City
10.0 out of 10, Exceptional, (5 reviews)
"Great place!!!"
United States
Cynthia B.
$157 nightly
The price is $166
Oct 20 - Oct 21
Total with taxes and fees
Riverfront Cabin with Private Dock
A bedroom with a large bed, a TV on a dresser, and a view of the city through large windows.

15. Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham
3.0 star property
Downtown Rochester
9.2 out of 10, Wonderful, (183 reviews)
"As always excellent staff, clean and comfortable rooms. Great central location. "
Canada
Anita
$169 nightly
The price is $195
Oct 3 - Oct 4
Total with taxes and fees
Broadway Plaza, Trademark Collection by Wyndham
A small brick building with a sign reading 'WYKOFF JAIL HOUSE.'

16. Wykoff Historical Jail Haus with Original Jail Cell Bunks.

Wykoff Historical Jail Haus with Original Jail Cell Bunks.
Wykoff
10.0 out of 10, Exceptional, (5 reviews)
"Phenomenal communication with Becky, our host. Will be coming to this property again. It is unique and unlike anything I ever stayed at before. It was a jail in its former life after all. Very authentic with a modern twist. Great place!!!"
United States
Peggy
$115 nightly
The price is $123
Sep 27 - Sep 28
Total with taxes and fees
Wykoff Historical Jail Haus with Original Jail Cell Bunks.
A wooden cabin interior with a dining table, chairs, a refrigerator, a stove, and a ladder leading to a loft.

17. Badger Cabin w/ Lofts, Fireplace & WiFi

Badger Cabin w/ Lofts, Fireplace & WiFi
Buffalo City
10.0 out of 10, Exceptional, (1 review)
"The cabin was adorable. Greg was great! The cabin was spotless. Great water pressure. It rained and it was lovely with the tin roof:) The tv reception was good and the wi - fi was great. Loved it!"
United States
Sharon M.
$175 nightly
The price is $185
Oct 14 - Oct 15
Total with taxes and fees
Badger Cabin w/ Lofts, Fireplace & WiFi
A kitchen with a bowl on a counter, a window with blinds, and a wall-mounted decoration.

18. Apple Blossom Cottage | 2 Mi from Mayo Clinic

Apple Blossom Cottage | 2 Mi from Mayo Clinic
Rochester
9.8 out of 10, Exceptional, (12 reviews)
"Very comfortable home away from home"
United States
ROBERT B.
$218 nightly
The price is $251
Sep 28 - Sep 29
Total with taxes and fees
Apple Blossom Cottage | 2 Mi from Mayo Clinic
A laundry area with stacked washers and dryers, a framed picture on the wall, and a decorative llama ornament.

19. Rose’s Barnhouse Loft | Cozy Farm-Inspired Stay

Rose’s Barnhouse Loft | Cozy Farm-Inspired Stay
East Side Pioneers
$134 nightly
The price is $137
Sep 26 - Sep 27
Total with taxes and fees
Rose’s Barnhouse Loft | Cozy Farm-Inspired Stay
A garden with a bench and various plants.

20. The Hen House Retreat - A Comfortable Place to Roost

The Hen House Retreat - A Comfortable Place to Roost
Highland
9.6 out of 10, Exceptional, (104 reviews)
"Comfortable place, beautiful spot!"
United States
Grace D.
$186 nightly
The price is $200
Sep 24 - Sep 25
Total with taxes and fees
The Hen House Retreat - A Comfortable Place to Roost
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top St. Charles Hotel Reviews

EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

10/10 Excellent
"Great breakfast"
Carl 2-night trip
Posted less than an hour ago
EVEN Hotel Rochester - Mayo Clinic Area by IHG

Find out more about St. Charles

Everything you need to know about St. Charles vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the St. Charles vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect St. Charles vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

St. Charles vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in St. Charles. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit St. Charles in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $173 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on St. Charles rentals

At Expedia, we put the best St. Charles vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top St. Charles rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream St. Charles vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around St. Charles. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find vacation rentals in St. Charles?

Yes, we offer vacation rentals close to the most popular attractions in St. Charles, or you can go with a more remote option if you want a relaxing place to stay. St. Charles is known for its parks.

What are some of the best vacation rentals that St. Charles has to offer?

Clean, fun, comfy ranch home near parks, 2.5 mi to Mayo w Pingpong and Playroom: Visitors like this St. Charles vacation home rental. It offers a patio, a garden, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the selection of games in this rental home to help you unwind.

What can I see and do in St. Charles?

While you're exploring the area, Whitewater River and Quarry Hill Nature Center are a couple of picturesque spots to get outside and enjoy nature. Whitewater State Park and St. Mary's University of Minnesota are a couple of places you'll find in the larger area.

What are vacation rentals like in St. Charles?

Vacation rentals are privately owned properties you can book for short or long periods in St. Charles. Vacation rentals feature amenities such as patios, hot tubs, and fire pits so your stay will be comfortable. If you're concerned about a clean environment, a vacation rental can offer a sense of seclusion away from public hotel elevators and lobbies bustling with people while still allowing you to travel. You'll also find more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is an attractive choice for families.