St. Charles Vacation Rentals

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Our top choices for St. Charles vacation rentals

Big River Escape Riverside Cabins

Big River Escape Riverside Cabins
3.0 star property
Cochrane
9.2 out of 10, Wonderful, (45 reviews)
"Super cozy, so clean, and such a good price! Second time we have stayed there and we will go back!"
United States
Marchell
$117 nightly
The price is $123
Apr 29 - Apr 30
Total with taxes and fees
Big River Escape Riverside Cabins

Big River Escape Parkside Bungalow

Big River Escape Parkside Bungalow
3.0 star property
Winona
10.0 out of 10, Exceptional, (1 review)
"We had a wonderful time and would defiinitely stay again. "
United States
Julie
$202 nightly
The price is $225
May 10 - May 11
Total with taxes and fees
Big River Escape Parkside Bungalow

Valley Cabin

Valley Cabin
Spring Valley
9.2 out of 10, Wonderful, (7 reviews)
"Great property with plenty of outdoor activities. Had fun fishing the stream and exploring the area. Dan is a great host and I will be visiting again."
United States
JAKE I.
$106 nightly
The price is $114
Apr 29 - Apr 30
Total with taxes and fees
Valley Cabin

Treehouse Cabin in the Bluff Woodlands

Treehouse Cabin in the Bluff Woodlands
Elba
9.8 out of 10, Exceptional, (16 reviews)
"Beautiful area enjoyed our stay immensely"
United Kingdom
I.M l.
$169 nightly
The price is $182
May 3 - May 4
Total with taxes and fees
Treehouse Cabin in the Bluff Woodlands

Vintage Lustron Home Piece of History

Vintage Lustron Home Piece of History
Minnesota City
10.0 out of 10, Exceptional, (30 reviews)
"Every thing was great! We always enjoy staying here. The home was excellent and we had no issues."
United States
Lynda S.
$196 nightly
The price is $211
Apr 29 - Apr 30
Total with taxes and fees
Vintage Lustron Home Piece of History

Farmhouse Apartment - River Road Historic Home

Farmhouse Apartment - River Road Historic Home
Fountain City
9.8 out of 10, Exceptional, (20 reviews)
"Great rental! Great location and very clean. Hidden gem!"
United States
Anthony y.
$223 nightly
The price is $235
Apr 29 - Apr 30
Total with taxes and fees
Farmhouse Apartment - River Road Historic Home

Treehouse Cabin in the Bluff Woodlands North

Treehouse Cabin in the Bluff Woodlands North
Elba
9.6 out of 10, Exceptional, (9 reviews)
"Great relaxing place! "
United States
James H.
$160 nightly
The price is $172
Apr 29 - Apr 30
Total with taxes and fees
Treehouse Cabin in the Bluff Woodlands North

Great River Road Cabin on the Mississippi Backwaters Eagle Cabin

Great River Road Cabin on the Mississippi Backwaters Eagle Cabin
Buffalo City
10.0 out of 10, Exceptional, (1 review)
"We had a wonderful stay. The cabin was beautiful and the property charming and a great view of the river. Really great location to run along the river if you are a runner!"
United States
Tracy R.
$166 nightly
The price is $175
Apr 29 - Apr 30
Total with taxes and fees
Great River Road Cabin on the Mississippi Backwaters Eagle Cabin

Charming 3-bedroom, 2 bathroom house with outdoor space in Winona

Charming 3-bedroom, 2 bathroom house with outdoor space in Winona
Winona
10.0 out of 10, Exceptional, (26 reviews)
"Beautiful home we had a wonderful stay!!!"
United States
Thomas L.
$297 nightly
The price is $320
Apr 29 - Apr 30
Total with taxes and fees
Charming 3-bedroom, 2 bathroom house with outdoor space in Winona

Big River Escape Grandview Manse

Big River Escape Grandview Manse
3.0 star property
Altura
10.0 out of 10, Exceptional, (4 reviews)
"It was very roomy and easily accessible. The views were amazing. Would recommend to anyone anytime!!"
United States
Greg
$331 nightly
The price is $356
May 10 - May 11
Total with taxes and fees
Big River Escape Grandview Manse

The Hen House Retreat - A Comfortable Place to Roost

The Hen House Retreat - A Comfortable Place to Roost
Highland
9.8 out of 10, Exceptional, (88 reviews)
"Very nice perfect for us, would rent again!"
United States
Mitchell G.
$185 nightly
The price is $199
May 3 - May 4
Total with taxes and fees
The Hen House Retreat - A Comfortable Place to Roost

Charming 1-bedroom house in delightful Winona with WiFi, AC and PRIVATE PATIO

Charming 1-bedroom house in delightful Winona with WiFi, AC and PRIVATE PATIO
Historic Downtown Winona
10.0 out of 10, Exceptional, (22 reviews)
"Had everything we needed and great communication for our weekend stay. "
United States
Tanya G.
$170 nightly
The price is $189
May 4 - May 5
Total with taxes and fees
Charming 1-bedroom house in delightful Winona with WiFi, AC and PRIVATE PATIO

Magical Nest Hideaway

Magical Nest Hideaway
Rochester
10.0 out of 10, Exceptional, (147 reviews)
"Great place to stay."
United States
Matthew S.
$104 nightly
The price is $120
May 7 - May 8
Total with taxes and fees
Magical Nest Hideaway

The Berkman

The Berkman
3.0 star property
Folwell
9.6 out of 10, Exceptional, (409 reviews)
"Great stay"
United States
Kayla
$225 nightly
The price is $259
May 22 - May 23
Total with taxes and fees
The Berkman

Charming Brick Farmhouse with a Touch of Elegance. -Winona

Charming Brick Farmhouse with a Touch of Elegance. -Winona
Winona
10.0 out of 10, Exceptional, (140 reviews)
"Excellent home and area!"
United States
Tracy W.
$421 nightly
The price is $453
Apr 29 - Apr 30
Total with taxes and fees
Charming Brick Farmhouse with a Touch of Elegance. -Winona

Meet Don - A Modern, Zero-step, Pet-friendly home in Rochester

Meet Don - A Modern, Zero-step, Pet-friendly home in Rochester
Slatterly Park
10.0 out of 10, Exceptional, (25 reviews)
"Host was great! Space was perfect along with the location"
United States
Lynn
$204 nightly
The price is $234
May 3 - May 4
Total with taxes and fees
Meet Don - A Modern, Zero-step, Pet-friendly home in Rochester

1 mile Mayo 2 step entry Encourage Covered ByFaith

1 mile Mayo 2 step entry Encourage Covered ByFaith
Parkway
10.0 out of 10, Exceptional, (1 review)
"Nice little place and close to the Mayo Clinic. It was perfect. "
United States
Philip
$219 nightly
The price is $253
May 4 - May 5
Total with taxes and fees
1 mile Mayo 2 step entry Encourage Covered ByFaith

King Suite Close to Mayo Clinic! Free Breakfast. Pool & Hot Tub.

King Suite Close to Mayo Clinic! Free Breakfast. Pool & Hot Tub.
Rochester
10.0 out of 10, Exceptional, (1 review)
"Good hotel with plenty of space to spread out. Great location with coffee and dining across the street. Easy to find and easy access to highways. Will stay here again!"
United States
Michael F.
$176 nightly
The price is $202
May 24 - May 25
Total with taxes and fees
King Suite Close to Mayo Clinic! Free Breakfast. Pool & Hot Tub.

Quiet 3 BDR Home- private sauna & skyline view- close to downtown & Mayo Clinic

Quiet 3 BDR Home- private sauna & skyline view- close to downtown & Mayo Clinic
Rochester
10.0 out of 10, Exceptional, (3 reviews)
"We enjoyed our stay here. Nice location easy to get to things in Rochester. "
United States
Jonathan P.
$406 nightly
The price is $467
Apr 29 - Apr 30
Total with taxes and fees
Quiet 3 BDR Home- private sauna & skyline view- close to downtown & Mayo Clinic

Discounted Charming 2-bedroom main-level TRIPLEX in Rochester

Discounted Charming 2-bedroom main-level TRIPLEX in Rochester
East Side Pioneers
9.0 out of 10, Wonderful, (15 reviews)
"Everything was perfect, couldn't ask for a better place to stay"
United States
Jason J.
$176 nightly
The price is $203
May 11 - May 12
Total with taxes and fees
Discounted Charming 2-bedroom main-level TRIPLEX in Rochester
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Charles Hotel Reviews

Find out more about St. Charles

Everything you need to know about St. Charles vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the St. Charles vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect St. Charles vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

St. Charles vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in St. Charles. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit St. Charles in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $114 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on St. Charles rentals

At Expedia, we put the best St. Charles vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top St. Charles rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream St. Charles vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around St. Charles. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find vacation rentals in St. Charles?

Yes, we offer vacation rentals close to the most popular attractions in St. Charles, or you can go with a more remote option if you want a relaxing place to stay. St. Charles is known for its parks.

What are some of the best vacation rentals that St. Charles has to offer?

Clean, fun, comfy ranch home near parks, 2.5 mi to Mayo w Pingpong and Playroom: Visitors like this St. Charles vacation home rental. It offers a patio, a garden, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the selection of games in this rental home to help you unwind.

What can I see and do in St. Charles?

While you're exploring the area, Whitewater River and Quarry Hill Nature Center are a couple of picturesque spots to get outside and enjoy nature. Whitewater State Park and St. Mary's University of Minnesota are a couple of places you'll find in the larger area.

What are vacation rentals like in St. Charles?

Vacation rentals are privately owned properties you can book for short or long periods in St. Charles. Vacation rentals feature amenities such as patios, hot tubs, and fire pits so your stay will be comfortable. If you're concerned about a clean environment, a vacation rental can offer a sense of seclusion away from public hotel elevators and lobbies bustling with people while still allowing you to travel. You'll also find more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is an attractive choice for families.