An aerial view of a town with industrial buildings, roads, and green areas.

St. Charles Vacation Rentals

Check prices for these dates

In two weeks
Nov 27 - Nov 29
In two months
Jan 8 - Jan 10
In three months
Feb 5 - Feb 7
In four months
Mar 5 - Mar 7

Our top choices for St. Charles vacation rentals

A small cabin with a wooden deck, a sofa, and a table.

1. Tiny Treehouse Cabin | Bluff Woodlands #2

Tiny Treehouse Cabin | Bluff Woodlands #2
Elba
9.8 out of 10, Exceptional, (17 reviews)
"Beautiful area enjoyed our stay immensely"
United Kingdom
I.M l.
$177 nightly
The price is $191
Nov 23 - Nov 24
Total with taxes and fees
Tiny Treehouse Cabin | Bluff Woodlands #2
A wooden cabin with a balcony, string lights, and outdoor furniture.

2. Tiny Treehouse Cabin | Bluff Woodlands #3

Tiny Treehouse Cabin | Bluff Woodlands #3
Elba
10.0 out of 10, Exceptional, (13 reviews)
"My family of 4 had a wonderful stay!"
United States
Josh S.
$189 nightly
The price is $204
Nov 23 - Nov 24
Total with taxes and fees
Tiny Treehouse Cabin | Bluff Woodlands #3
An open wooden door leading to a wooden deck with a grassy yard and a green tractor in the background.

3. Valley Cabin

Valley Cabin
Spring Valley
9.2 out of 10, Wonderful, (7 reviews)
"Great property with plenty of outdoor activities. Had fun fishing the stream and exploring the area. Dan is a great host and I will be visiting again."
United States
JAKE I.
$104 nightly
The price is $112
Dec 1 - Dec 2
Total with taxes and fees
Valley Cabin
A wooden deck with a railing, a table, and two chairs.

4. Tiny Treehouse Cabin | Bluff Woodlands #1

Tiny Treehouse Cabin | Bluff Woodlands #1
Elba
9.8 out of 10, Exceptional, (11 reviews)
"Great area a place to stay. "
United States
Paul T.
$189 nightly
The price is $204
Nov 23 - Nov 24
Total with taxes and fees
Tiny Treehouse Cabin | Bluff Woodlands #1
A compact kitchen with white appliances, a weekly planner on the fridge, and a dining area with a table and chairs.

5. Viola Suite #1 | 1 bed, 1.5 Bath, Pets Welcome

Viola Suite #1 | 1 bed, 1.5 Bath, Pets Welcome
Rochester
10.0 out of 10, Exceptional, (4 reviews)
"Lovely apartment with everything you need and a great host!"
United States
Mikayla B.
$183 nightly
The price is $197
Nov 22 - Nov 23
Total with taxes and fees
Viola Suite #1 | 1 bed, 1.5 Bath, Pets Welcome
A kitchen with white cabinets, a wooden countertop, a chandelier, and a window.

6. Discounted Charming 2-bedroom main-level TRIPLEX in Rochester

Discounted Charming 2-bedroom main-level TRIPLEX in Rochester
East Side Pioneers
9.4 out of 10, Exceptional, (25 reviews)
"Very clean place with a very welcoming environment made us feel right at home!!"
United States
Nadaley W.
$195 nightly
The price is $224
Nov 23 - Nov 24
Total with taxes and fees
Discounted Charming 2-bedroom main-level TRIPLEX in Rochester
A white door with a keypad lock and a small sign on it.

7. 1mile Mayo 2 step entry Encourage CoveredByFaith

1mile Mayo 2 step entry Encourage CoveredByFaith
Parkway
10.0 out of 10, Exceptional, (2 reviews)
"Nice little place and close to the Mayo Clinic. It was perfect. "
United States
Philip
$217 nightly
The price is $251
Nov 19 - Nov 20
Total with taxes and fees
1mile Mayo 2 step entry Encourage CoveredByFaith
A living room with a dark blue armchair, a black entertainment unit with a TV displaying a scenic view, a white door, and a window with a view of a car outside.

8. 1mile to Mayo 2 step entry Brave Covered By Faith

1mile to Mayo 2 step entry Brave Covered By Faith
Parkway
10.0 out of 10, Exceptional, (11 reviews)
"This was a PERFECT place to stay if you're going to the Mayo!Jessica is very easy to work with and incredibly responsive!"
United States
Kristin T.
$226 nightly
The price is $260
Nov 18 - Nov 19
Total with taxes and fees
1mile to Mayo 2 step entry Brave Covered By Faith
A two-story house with a covered patio and a pathway leading to the entrance.

9. Magical Nest Hideaway

Magical Nest Hideaway
Rochester
10.0 out of 10, Exceptional, (172 reviews)
"This was perfect place for our 2 night stay. Clean and comfortable and at the right price!"
United States
Pam N.
$149 nightly
The price is $172
Nov 16 - Nov 17
Total with taxes and fees
Magical Nest Hideaway
A coffee bar setup with a mirror, coffee machines, and a sign reading "Coffee Bar".

10. Vintage Lustron Home Piece of History

Vintage Lustron Home Piece of History
Minnesota City
10.0 out of 10, Exceptional, (36 reviews)
"A beautiful comfortable welcoming home!"
United States
Jocelyn R.
$190 nightly
The price is $205
Nov 16 - Nov 17
Total with taxes and fees
Vintage Lustron Home Piece of History
A covered outdoor deck with a wooden floor, black metal railing, and a table with two chairs.

11. Three Tiny Treehouse Cabins in the Bluff Woodlands

Three Tiny Treehouse Cabins in the Bluff Woodlands
Elba
$518 nightly
The price is $558
Nov 23 - Nov 24
Total with taxes and fees
Three Tiny Treehouse Cabins in the Bluff Woodlands
A backyard with a picnic table, string lights, and a wooden fence.

12. Rose’s Barnhouse | Charming 2BR Near Mayo

Rose’s Barnhouse | Charming 2BR Near Mayo
East Side Pioneers
$151 nightly
The price is $153
Nov 16 - Nov 17
Total with taxes and fees
Rose’s Barnhouse | Charming 2BR Near Mayo
A kitchen with white cabinets, a sink, and a coffee maker.

13. Cozy 2BR Near Mayo — Great Rate

Cozy 2BR Near Mayo — Great Rate
Rochester
9.4 out of 10, Exceptional, (35 reviews)
"Close to Mayo's and shopping."
United States
Cathy
$206 nightly
The price is $237
Nov 20 - Nov 21
Total with taxes and fees
Cozy 2BR Near Mayo — Great Rate
A modern kitchen with stainless steel appliances, white cabinetry, and a window with a view of greenery.

14. The Little House | 1 mi from downtown, Love Pets!

The Little House | 1 mi from downtown, Love Pets!
Slatterly Park
10.0 out of 10, Exceptional, (23 reviews)
"Beautiful little house and comfortable stay."
United States
Cheryl P.
$226 nightly
The price is $260
Nov 22 - Nov 23
Total with taxes and fees
The Little House | 1 mi from downtown, Love Pets!
A living room with a flat-screen TV on a wooden stand, a gray sofa, and a blue armchair.

15. Close to Mayo/Shops, 1 step entry Covered By Faith

Close to Mayo/Shops, 1 step entry Covered By Faith
Rochester
9.8 out of 10, Exceptional, (13 reviews)
"Peaceful and relaxing, perfect vacation home. Excellent hosts!!!"
United States
Ellaina M.
$236 nightly
The price is $272
Nov 16 - Nov 17
Total with taxes and fees
Close to Mayo/Shops, 1 step entry Covered By Faith
A wooden staircase with a dark blue door on the left and a brick wall on the right.

16. Across from St Marys hospital Covered By Faith 2

Across from St Marys hospital Covered By Faith 2
Kutzky Park
8.0 out of 10, Very good, (2 reviews)
"Easy check in/ Secure entry system "
United States
Ann R.
$128 nightly
The price is $148
Nov 16 - Nov 17
Total with taxes and fees
Across from St Marys hospital Covered By Faith 2
A modern bathroom vanity with a black countertop, a framed WiFi sign, a vase with dried flowers, and a clock.

17. Cozy 3BR near Mayo and downtown. Charming, spotless, and designed for comfort with restful bedrooms, a stocked kitchen, and two welcoming living spaces. Perfect for Mayo visits, business trips, or family stays. Dogs allowed, too.

Cozy 3BR near Mayo and downtown. Charming, spotless, and designed for comfort with restful bedrooms, a stocked kitchen, and two welcoming living spaces. Perfect for Mayo visits, business trips, or family stays. Dogs allowed, too.
Rochester
10.0 out of 10, Exceptional, (13 reviews)
"Nice place to stay, close to all the activities we wanted to do."
United States
Kimberly K.
$419 nightly
The price is $480
Nov 20 - Nov 21
Total with taxes and fees
Cozy 3BR near Mayo and downtown. Charming, spotless, and designed for comfort with restful bedrooms, a stocked kitchen, and two welcoming living spaces. Perfect for Mayo visits, business trips, or family stays. Dogs allowed, too.
A modern living room with a white sofa, a black coffee table, a TV, and a decorative chair.

18. Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham
3.0 star property
Downtown Rochester
9.2 out of 10, Wonderful, (189 reviews)
"Clean room and great location"
United States
Jennifer
$169 nightly
The price is $195
Nov 27 - Nov 28
Total with taxes and fees
Broadway Plaza, Trademark Collection by Wyndham
A spacious living area with a modern staircase, leather sofas, and contemporary lighting.

19. The Berkman

The Berkman
3.0 star property
Folwell
9.6 out of 10, Exceptional, (456 reviews)
"Excellent service and wonderful room!"
United States
Suzette
$210 nightly
The price is $241
Dec 1 - Dec 2
Total with taxes and fees
The Berkman
A rustic wooden pavilion with picnic tables, surrounded by a gravel area and grassy lawn.

20. Cozy River Cabin w/ Loft & Screened Porch

Cozy River Cabin w/ Loft & Screened Porch
Buffalo City
10.0 out of 10, Exceptional, (2 reviews)
"It was a in and out stay. Would have liked to been able to check in earlier since we came from a distance and woulda been nice to have a place to change church clothes without a fee. Other than that all worked out."
United States
John S.
$148 nightly
The price is $156
Nov 30 - Dec 1
Total with taxes and fees
Cozy River Cabin w/ Loft & Screened Porch
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Charles Hotel Reviews

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

10/10 Excellent
"The room and the common areas were clean and felt safe. Downtown area near the hotel were the same. Very pleasant stay. It was extremely convenient for the concert at the Mayo Civic Auditorium we went to. Skyway meant an indoor walk the entire way. Parking was also convenient as it connects directly to the hotel."
Robert 1-night trip
Posted 2 hours ago
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Find out more about St. Charles

Everything you need to know about St. Charles vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the St. Charles vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect St. Charles vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

St. Charles vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in St. Charles. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit St. Charles in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $162 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on St. Charles rentals

At Expedia, we put the best St. Charles vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top St. Charles rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream St. Charles vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around St. Charles. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find vacation rentals in St. Charles?

Yes, we offer vacation rentals close to the most popular attractions in St. Charles, or you can go with a more remote option if you want a relaxing place to stay. St. Charles is known for its parks.

What are some of the best vacation rentals that St. Charles has to offer?

Clean, fun, comfy ranch home near parks, 2.5 mi to Mayo w Pingpong and Playroom: Visitors like this St. Charles vacation home rental. It offers a patio, a garden, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the selection of games in this rental home to help you unwind.

What can I see and do in St. Charles?

While you're exploring the area, Whitewater River and Quarry Hill Nature Center are a couple of picturesque spots to get outside and enjoy nature. Whitewater State Park and St. Mary's University of Minnesota are a couple of places you'll find in the larger area.

What are vacation rentals like in St. Charles?

Vacation rentals are privately owned properties you can book for short or long periods in St. Charles. Vacation rentals feature amenities such as patios, hot tubs, and fire pits so your stay will be comfortable. If you're concerned about a clean environment, a vacation rental can offer a sense of seclusion away from public hotel elevators and lobbies bustling with people while still allowing you to travel. You'll also find more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is an attractive choice for families.