$221 Cheap avianca flights Medellín (MDE) to Cusco (CUZ)

Grab affordable return AVIANCA flights from $395 from MDE to CUZ by sorting your results from "Price (lowest to highest)" on Expedia. Or search for bargains from $221 for a one-way journey.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Getting the best AVIANCA deals from MDE to CUZ often comes down to booking at the right moment. You can save 17% on international flights when you book 18 to 29 days before takeoff instead of four to five months ahead. What's more, you can pocket 17% on average by buying your tickets on a Sunday rather than a Friday, which is often the most expensive day to book.* It's smart to kick off your flight search about one month before you plan to travel.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Find AVIANCA's earliest flights from MDE to CUZ by checking our "Morning" and "Early Morning" filters. Not only will you get to your destination sooner, early departures also experience 20% fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.

Fly from MDE to CUZ with AVIANCA and look forward to a range of benefits starting with a rewarding loyalty program. When you book through Expedia as an Avianca LifeMiles and One Key™ member, you may also earn OneKeyCash™* to use on select future travel purchases.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.