$170 Cheap Flights from Antofagasta (ANF) to Cusco (CUZ)

View $170 flight on Sat, Nov 8, 2025Opens in a new window

Popular airlines from Antofagasta (ANF-Cerro Moreno Intl.) to Alejandro Velasco Astete Intl. Airport (CUZ)

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Cheap Flights from Antofagasta to Cusco (ANF-CUZ)

Prices were available within the past 7 days and start at $170 for one-way flights and $290 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

LATAM Airlines Group
Tue, Nov 25 - Wed, Dec 10
ANF
Antofagasta
CUZ
Cusco
$290 Roundtrip, found 3 days ago
$290
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Tue, Nov 25 from Antofagasta to Cusco, returning Wed, Dec 10, priced at $290 found 3 days ago
LATAM Airlines Group
Mon, Dec 22 - Mon, Jan 5
ANF
Antofagasta
CUZ
Cusco
$291 Roundtrip, found 3 days ago
$291
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Mon, Dec 22 from Antofagasta to Cusco, returning Mon, Jan 5, priced at $291 found 3 days ago
LATAM Airlines Group
Tue, Nov 25 - Thu, Dec 11
ANF
Antofagasta
CUZ
Cusco
$295 Roundtrip, found 3 days ago
$295
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Tue, Nov 25 from Antofagasta to Cusco, returning Thu, Dec 11, priced at $295 found 3 days ago
LATAM Airlines Group
Mon, Dec 22 - Fri, Jan 9
ANF
Antofagasta
CUZ
Cusco
$298 Roundtrip, found 3 days ago
$298
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Mon, Dec 22 from Antofagasta to Cusco, returning Fri, Jan 9, priced at $298 found 3 days ago
LATAM Airlines Group
Sun, Nov 16 - Wed, Dec 3
ANF
Antofagasta
CUZ
Cusco
$302 Roundtrip, found 3 days ago
$302
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Sun, Nov 16 from Antofagasta to Cusco, returning Wed, Dec 3, priced at $302 found 3 days ago
LATAM Airlines Group
Sun, Nov 23 - Wed, Dec 10
ANF
Antofagasta
CUZ
Cusco
$303 Roundtrip, found 3 days ago
$303
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Sun, Nov 23 from Antofagasta to Cusco, returning Wed, Dec 10, priced at $303 found 3 days ago
LATAM Airlines Group
Tue, Nov 25 - Fri, Dec 12
ANF
Antofagasta
CUZ
Cusco
$303 Roundtrip, found 3 days ago
$303
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Tue, Nov 25 from Antofagasta to Cusco, returning Fri, Dec 12, priced at $303 found 3 days ago
LATAM Airlines Group
Sat, Nov 22 - Wed, Dec 10
ANF
Antofagasta
CUZ
Cusco
$306 Roundtrip, found 3 days ago
$306
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Sat, Nov 22 from Antofagasta to Cusco, returning Wed, Dec 10, priced at $306 found 3 days ago
LATAM Airlines Group
Mon, Dec 22 - Wed, Jan 7
ANF
Antofagasta
CUZ
Cusco
$306 Roundtrip, found 3 days ago
$306
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Mon, Dec 22 from Antofagasta to Cusco, returning Wed, Jan 7, priced at $306 found 3 days ago
SKY AIRLINE
Sat, Nov 29 - Tue, Dec 16
ANF
Antofagasta
CUZ
Cusco
$356 Roundtrip, found 3 days ago
$356
Roundtrip
found 3 days ago
Select SKY AIRLINE flight, departing Sat, Nov 29 from Antofagasta to Cusco, returning Tue, Dec 16, priced at $356 found 3 days ago

Alternative airports near Cusco

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Alejandro Velasco Astete Intl. CUZ. Cheapest and Closest option available. Average driving time to city center is 4 minutes. Flights from $325
CUZ
Alejandro Velasco Astete Intl.
CheapestClosest
Average driving time to city center4 min
Flights from $325
Flights from Antofagasta (ANF) to Cusco (CUZ)
Origin airport
Cerro Moreno Intl.
Destination airport
Alejandro Velasco Astete Intl.
Roundtrip price
$289
Distance
691 mi

Antofagasta to Cusco Flights

The cheapest times to fly from Antofagasta to Cusco

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Antofagasta to Cusco are during the month of November. You can find some of the cheapest flights from Antofagasta to Cusco with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Antofagasta to Cusco

Sunday is one of the best days to book for cheap flights from Antofagasta to Cusco: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Antofagasta to Cusco

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Antofagasta to Cusco in 2025. You can also book with separate airlines for your outbound and return journeys, from $170 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Antofagasta to Cusco flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Antofagasta to Cusco airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Cerro Moreno Intl. Airport (ANF) to Alejandro Velasco Astete Intl. Airport (CUZ) cost?
Get a cheap one-way flight from $170 or cheap return flight from $290 from Cerro Moreno Intl. Airport (ANF) to Alejandro Velasco Astete Intl. Airport (CUZ) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Cerro Moreno Intl. Airport (ANF) to Alejandro Velasco Astete Intl. Airport (CUZ)?
November is the least expensive month to fly from ANF to CUZ. Planning your trip for the off-season is often the key to better flight prices.
What is the cheapest airline that flies from Cerro Moreno Intl. Airport (ANF) to Alejandro Velasco Astete Intl. Airport (CUZ)?
Use the filters on Expedia to compare airlines and find the most affordable carrier that'll take you from ANF to CUZ. Then, sort your results by "Price (lowest to highest)" to score the best deal available.
How many flights per day from Cerro Moreno Intl. Airport (ANF) to Alejandro Velasco Astete Intl. Airport (CUZ)?
There are no daily nonstop flights available from Cerro Moreno Intl. Airport (ANF) to Alejandro Velasco Astete Intl. Airport (CUZ). But you can opt for flights with layovers. Filter your search results on Expedia to include one or two stops, and you'll be cruising above the clouds in no time at all.
What day of the week has the most flights from ANF to CUZ?
You'll generally find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Cerro Moreno Intl. Airport (ANF) to Alejandro Velasco Astete Intl. Airport (CUZ)?
To arrive at Alejandro Velasco Astete Intl. Airport (CUZ) without delays, opt for a flight that leaves Cerro Moreno Intl. Airport (ANF) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Cerro Moreno Intl. Airport (ANF) to Alejandro Velasco Astete Intl. Airport (CUZ) last-minute?
Waiting until just before your trip to book a flight from ANF to CUZ generally means paying more. While it's possible to find some last-minute deals, they're not always guaranteed. Keep your travel schedule open for the best chance of snagging a bargain.
Is it cheaper to book an ANF to CUZ flight and hotel package?
Securing an ANF to CUZ flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels in one place. Pick from our impressive range of accommodations and then add car rentals, flights and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Cerro Moreno Intl. Airport (ANF) to Alejandro Velasco Astete Intl. Airport (CUZ)?
Typically, you're able to reschedule or cancel your ANF to CUZ flight. However, there may be additional fees, especially if you made your booking more than 24 hours ago. Double-check your itinerary for the airline's fees and guidelines on flight changes, or if you'd like further information, go to our Customer Service portal.

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*Available to One Key members.