$221 Cheap Flights from Charlotte (CLT) to Panama City (PTY)

View $221 flight on Thu, Nov 13, 2025Opens in a new window

Popular airlines from Charlotte-Douglas Intl. Airport (CLT) to Tocumen Intl. Airport (PTY)

Cheap Flights from Charlotte to Panama City (CLT-PTY)

Prices were available within the past 7 days and start at $221 for one-way flights and $400 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Tue, Dec 9 - Tue, Dec 16
CLT
Charlotte
PTY
Panama City
$400 Roundtrip, found 7 hours ago
$400
Roundtrip
found 7 hours ago
Select Delta flight, departing Tue, Dec 9 from Charlotte to Panama City, returning Tue, Dec 16, priced at $400 found 7 hours ago
United
Thu, Feb 12 - Mon, Feb 16
CLT
Charlotte
PTY
Panama City
$400 Roundtrip, found 5 hours ago
$400
Roundtrip
found 5 hours ago
Select United flight, departing Thu, Feb 12 from Charlotte to Panama City, returning Mon, Feb 16, priced at $400 found 5 hours ago
American Airlines
Mon, Dec 15 - Fri, Dec 19
CLT
Charlotte
PTY
Panama City
$404 Roundtrip, found 7 hours ago
$404
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Mon, Dec 15 from Charlotte to Panama City, returning Fri, Dec 19, priced at $404 found 7 hours ago
Delta
Tue, Nov 18 - Wed, Nov 26
CLT
Charlotte
PTY
Panama City
$406 Roundtrip, found 19 hours ago
$406
Roundtrip
found 19 hours ago
Select Delta flight, departing Tue, Nov 18 from Charlotte to Panama City, returning Wed, Nov 26, priced at $406 found 19 hours ago
Delta
Mon, Dec 8 - Thu, Dec 11
CLT
Charlotte
PTY
Panama City
$412 Roundtrip, found 14 hours ago
$412
Roundtrip
found 14 hours ago
Select Delta flight, departing Mon, Dec 8 from Charlotte to Panama City, returning Thu, Dec 11, priced at $412 found 14 hours ago
United
Tue, Dec 2 - Tue, Dec 9
CLT
Charlotte
PTY
Panama City
$416 Roundtrip, found 4 days ago
$416
Roundtrip
found 4 days ago
Select United flight, departing Tue, Dec 2 from Charlotte to Panama City, returning Tue, Dec 9, priced at $416 found 4 days ago
United
Thu, Dec 4 - Mon, Dec 8
CLT
Charlotte
PTY
Panama City
$417 Roundtrip, found 2 days ago
$417
Roundtrip
found 2 days ago
Select United flight, departing Thu, Dec 4 from Charlotte to Panama City, returning Mon, Dec 8, priced at $417 found 2 days ago
American Airlines
Thu, Jan 8 - Tue, Jan 13
CLT
Charlotte
PTY
Panama City
$417 Roundtrip, found 6 hours ago
$417
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Thu, Jan 8 from Charlotte to Panama City, returning Tue, Jan 13, priced at $417 found 6 hours ago
American Airlines
Tue, Dec 2 - Sat, Dec 6
CLT
Charlotte
PTY
Panama City
$420 Roundtrip, just found
$420
Roundtrip
just found
Select American Airlines flight, departing Tue, Dec 2 from Charlotte to Panama City, returning Sat, Dec 6, priced at $420 just found
Copa
Sat, May 30 - Sat, Jun 6
CLT
Charlotte
PTY
Panama City
$728 Roundtrip, found 4 hours ago
$728
Roundtrip
found 4 hours ago
Select Copa flight, departing Sat, May 30 from Charlotte to Panama City, returning Sat, Jun 6, priced at $728 found 4 hours ago

Find the cheapest month to fly from Charlotte (CLT) to Panama City (PTY)

September is typically the cheapest month to fly

From $395 - $1,137 per traveler.

Alternative airports near Panama City

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Tocumen Intl. PTY. Cheapest option available. Average driving time to city center is 16 minutes. Flights from $579
PTY
Tocumen Intl.
Cheapest
Average driving time to city center16 min
Flights from $579

Frequently asked questions

How much does a flight from Charlotte-Douglas Intl. Airport (CLT) to Tocumen Intl. Airport (PTY) cost?
Snag a cheap one-way flight from $221 or cheap return flight from $400 from Charlotte-Douglas Intl. Airport (CLT) to Tocumen Intl. Airport (PTY) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Charlotte-Douglas Intl. Airport (CLT) to Tocumen Intl. Airport (PTY)?
The cheapest month to fly from CLT to PTY is December, when there's less demand. Off-peak months are often when airlines offer lower prices between these airports.
What is the cheapest airline that flies from Charlotte-Douglas Intl. Airport (CLT) to Tocumen Intl. Airport (PTY)?
Use the filters on Expedia to compare airlines and find the most affordable carrier that'll take you from CLT to PTY. Then, sort your results by "Price (lowest to highest)" to score a great deal.
How many flights per day from Charlotte-Douglas Intl. Airport (CLT) to Tocumen Intl. Airport (PTY)?
There are no daily direct flights available from Charlotte-Douglas Intl. Airport (CLT) to Tocumen Intl. Airport (PTY). But you can opt for flights with layovers. Filter your search results on Expedia to include one or two stops, and you'll be on your way in no time at all.
What day of the week has the most flights from CLT to PTY?
Friday is typically the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can vary depending on a range of factors, such as the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Charlotte-Douglas Intl. Airport (CLT) to Tocumen Intl. Airport (PTY)?
Book a flight from Charlotte-Douglas Intl. Airport (CLT) to Tocumen Intl. Airport (PTY) that takes off before 3 PM to reduce the risk of cancellations. Departures after this hour are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Charlotte-Douglas Intl. Airport (CLT) to Tocumen Intl. Airport (PTY) last-minute?
Booking your ticket from CLT to PTY right before your journey is usually more expensive. But if there's some wiggle room with your travel times and dates, you could snag a cheap last-minute fare.
Is it cheaper to book a CLT to PTY flight and hotel package?
Compared with arranging flights and hotels separately, booking a CLT to PTY flight and hotel package with Expedia could lead to significant savings. Better yet, having it all in one place takes the hassle out of travel planning. Simply secure your flights and choose from our wide range of hotels, then customize your trip with extras like tours and car rentals.
Can I cancel or change the date of my flight from Charlotte-Douglas Intl. Airport (CLT) to Tocumen Intl. Airport (PTY)?
If you booked your CLT to PTY flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal if you want more information.

Travel information

Origin airport
Charlotte-Douglas Intl.
Destination airport
Tocumen Intl.
Airlines serving
American Airlines, Copa, Delta, United
Roundtrip price
$399
Distance
1809 mi

Book with confidence

Charlotte to Panama City Flights

The cheapest times to fly from Charlotte to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Charlotte to Panama City are during the month of December. You can find some of the cheapest flights from Charlotte to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Charlotte to Panama City

Sunday is one of the best days to book for cheap flights from Charlotte to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Charlotte to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Charlotte to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $221 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Charlotte to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Charlotte to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Charlotte to Panama City Flights

Explore a world of travel with Expedia

*Available to One Key members.