$325 Cheap Flights from Cuenca (CUE) to Santiago (SCL)

View $325 flight on Mon, Nov 2, 2026Opens in a new window

Popular airlines from Cuenca (CUE-Mariscal Lamar) to Santiago Intl. Airport (SCL)

Cheap Flights from Cuenca to Santiago (CUE-SCL)

Prices were available within the past 7 days and start at $325 for one-way flights and $604 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

LATAM Airlines Group
Tue, May 26 - Wed, Sep 30
CUE
Cuenca
SCL
Santiago
$604 Roundtrip, found 9 hours ago
$604
Roundtrip
found 9 hours ago
Select LATAM Airlines Group flight, departing Tue, May 26 from Cuenca to Santiago, returning Wed, Sep 30, priced at $604 found 9 hours ago
LATAM Airlines Group
Tue, May 26 - Wed, Sep 30
CUE
Cuenca
SCL
Santiago
$610 Roundtrip, found 9 hours ago
$610
Roundtrip
found 9 hours ago
Select LATAM Airlines Group flight, departing Tue, May 26 from Cuenca to Santiago, returning Wed, Sep 30, priced at $610 found 9 hours ago
LATAM Airlines Group
Mon, Nov 2 - Fri, Nov 6
CUE
Cuenca
SCL
Santiago
$611 Roundtrip, found 1 hour ago
$611
Roundtrip
found 1 hour ago
Select LATAM Airlines Group flight, departing Mon, Nov 2 from Cuenca to Santiago, returning Fri, Nov 6, priced at $611 found 1 hour ago
LATAM Airlines Group
Tue, May 26 - Wed, Sep 30
CUE
Cuenca
SCL
Santiago
$617 Roundtrip, found 9 hours ago
$617
Roundtrip
found 9 hours ago
Select LATAM Airlines Group flight, departing Tue, May 26 from Cuenca to Santiago, returning Wed, Sep 30, priced at $617 found 9 hours ago
LATAM Airlines Group
Mon, Nov 2 - Fri, Nov 6
CUE
Cuenca
SCL
Santiago
$621 Roundtrip, found 1 hour ago
$621
Roundtrip
found 1 hour ago
Select LATAM Airlines Group flight, departing Mon, Nov 2 from Cuenca to Santiago, returning Fri, Nov 6, priced at $621 found 1 hour ago
LATAM Airlines Group
Mon, Nov 2 - Fri, Nov 6
CUE
Cuenca
SCL
Santiago
$623 Roundtrip, found 1 hour ago
$623
Roundtrip
found 1 hour ago
Select LATAM Airlines Group flight, departing Mon, Nov 2 from Cuenca to Santiago, returning Fri, Nov 6, priced at $623 found 1 hour ago
LATAM Airlines Group
Tue, May 26 - Wed, Sep 30
CUE
Cuenca
SCL
Santiago
$625 Roundtrip, found 9 hours ago
$625
Roundtrip
found 9 hours ago
Select LATAM Airlines Group flight, departing Tue, May 26 from Cuenca to Santiago, returning Wed, Sep 30, priced at $625 found 9 hours ago
LATAM Airlines Group
Tue, May 26 - Wed, Sep 30
CUE
Cuenca
SCL
Santiago
$627 Roundtrip, found 9 hours ago
$627
Roundtrip
found 9 hours ago
Select LATAM Airlines Group flight, departing Tue, May 26 from Cuenca to Santiago, returning Wed, Sep 30, priced at $627 found 9 hours ago
LATAM Airlines Group
Tue, May 26 - Wed, Sep 30
CUE
Cuenca
SCL
Santiago
$629 Roundtrip, found 9 hours ago
$629
Roundtrip
found 9 hours ago
Select LATAM Airlines Group flight, departing Tue, May 26 from Cuenca to Santiago, returning Wed, Sep 30, priced at $629 found 9 hours ago
avianca
Mon, Nov 2 - Fri, Nov 6
CUE
Cuenca
SCL
Santiago
$683 Roundtrip, found 1 hour ago
$683
Roundtrip
found 1 hour ago
Select avianca flight, departing Mon, Nov 2 from Cuenca to Santiago, returning Fri, Nov 6, priced at $683 found 1 hour ago

Alternative airports near Santiago

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Arturo Merino Benitez SCL. Cheapest and Closest option available. Average driving time to city center is 17 minutes. Flights from $671
SCL
Arturo Merino Benitez
CheapestClosest
Average driving time to city center17 min
Flights from $671

Frequently asked questions

How much does a flight from Cuenca (CUE-Mariscal Lamar) to Santiago (SCL-Arturo Merino Benitez) cost?
You can find cheap one-way flights from $325 and cheap return flights from $604 Cuenca (CUE-Mariscal Lamar) to Santiago (SCL-Arturo Merino Benitez) with Expedia. Return flights often range between $844 and $2692. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Cuenca (CUE-Mariscal Lamar) to Santiago (SCL-Arturo Merino Benitez) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Cuenca (CUE-Mariscal Lamar) to Santiago (SCL-Arturo Merino Benitez)?
The cheapest month to fly from CUE to SCL is May when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Cuenca (CUE-Mariscal Lamar) to Santiago (SCL-Arturo Merino Benitez)?
Enter CUE to SCL and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
How do I find cheap flights from Cuenca (CUE-Mariscal Lamar) to Santiago (SCL-Arturo Merino Benitez)?
To find a cheap flight from Cuenca (CUE-Mariscal Lamar) to Santiago (SCL-Arturo Merino Benitez), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Cuenca (CUE-Mariscal Lamar) to Santiago (SCL-Arturo Merino Benitez)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Cuenca (CUE-Mariscal Lamar) to Santiago (SCL-Arturo Merino Benitez)?
The earliest flight from Mariscal Lamar Airport (CUE) in Cuenca to Arturo Merino Benitez Airport (SCL) in Santiago typically departs at around 7:45 AM, operated by Avianca. This seasonal service is available in December, giving you a great opportunity to start your day in Santiago. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Cuenca (CUE-Mariscal Lamar) to Santiago (SCL-Arturo Merino Benitez)?
When flying from Cuenca (CUE) to Santiago (SCL), the most popular departure times are from 9am to 12pm. Approximately 36% of passengers choose this time window. Major airlines like Avianca and LATAM operate flights during this period. This timing works well for travelers who want to arrive in Santiago with plenty of daylight to explore.
How long does it take to fly from Cuenca (CUE-Mariscal Lamar) to Santiago (SCL-Arturo Merino Benitez)?
Flying from CUE to SCL with a connection usually takes about 8 hours 20 minutes, traveling roughly 2,173 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Cuenca (CUE-Mariscal Lamar) to Santiago (SCL-Arturo Merino Benitez)?
Select the "Business class" and "First class" filters when looking for CUE to SCL flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Cuenca (CUE-Mariscal Lamar) to Santiago (SCL-Arturo Merino Benitez) flight with Expedia?
It's easy to earn miles on a Cuenca (CUE-Mariscal Lamar) to Santiago (SCL-Arturo Merino Benitez) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Santiago from Mariscal Lamar (CUE)?
From Mariscal Lamar (CUE), you can fly into Arturo Merino Benitez (SCL) to reach Santiago. Some flights may connect through major hubs like Mariscal Sucre Intl. (UIO), Jose Joaquin de Olmedo Intl. (GYE) before reaching Santiago. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Cuenca (CUE-Mariscal Lamar) to Santiago (SCL-Arturo Merino Benitez) at the last minute?
Typically, booking a last minute flight from Cuenca (CUE-Mariscal Lamar) to Santiago (SCL-Arturo Merino Benitez) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Cuenca (CUE-Mariscal Lamar) to Santiago (SCL-Arturo Merino Benitez) flight and hotel package?
Securing a Cuenca (CUE-Mariscal Lamar) to Santiago (SCL-Arturo Merino Benitez) Santiago Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Cuenca (CUE-Mariscal Lamar) to Santiago (SCL-Arturo Merino Benitez)?
If you booked your Cuenca (CUE-Mariscal Lamar) to Santiago (SCL-Arturo Merino Benitez) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Mariscal Lamar
Destination airport
Arturo Merino Benitez
Airlines serving
LATAM Airlines Group, avianca
Roundtrip price
$603
Distance
2173 mi

Book with confidence

Cuenca to Santiago Flights

The cheapest times to fly from Cuenca to Santiago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Cuenca to Santiago are during the month of May. You can find some of the cheapest flights from Cuenca to Santiago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Cuenca to Santiago

Sunday is one of the best days to book for cheap flights from Cuenca to Santiago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Cuenca to Santiago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Cuenca to Santiago in 2026. You can also book with separate airlines for your outbound and return journeys, from $325 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Cuenca to Santiago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Cuenca to Santiago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Cuenca to Santiago Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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