$151 Cheap Flights from Cancun (CUN) to Panama City (PTY)

View $151 flight on Wed, Nov 12, 2025Opens in a new window

Popular airlines from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY)

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Cheap Flights from Cancun to Panama City (CUN-PTY)

Prices were available within the past 7 days and start at $151 for one-way flights and $318 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Thu, Dec 4 - Fri, Dec 5
CUN
Cancun
PTY
Panama City
$318 Roundtrip, found 4 hours ago
$318
Roundtrip
found 4 hours ago
Select Copa flight, departing Thu, Dec 4 from Cancun to Panama City, returning Fri, Dec 5, priced at $318 found 4 hours ago
Aeromexico
Mon, Feb 9 - Mon, Feb 16
CUN
Cancun
PTY
Panama City
$320 Roundtrip, just found
$320
Roundtrip
just found
Select Aeromexico flight, departing Mon, Feb 9 from Cancun to Panama City, returning Mon, Feb 16, priced at $320 just found
Copa
Thu, Dec 4 - Fri, Dec 5
CUN
Cancun
PTY
Panama City
$329 Roundtrip, found 4 hours ago
$329
Roundtrip
found 4 hours ago
Select Copa flight, departing Thu, Dec 4 from Cancun to Panama City, returning Fri, Dec 5, priced at $329 found 4 hours ago
avianca
Mon, Feb 9 - Mon, Feb 16
CUN
Cancun
PTY
Panama City
$339 Roundtrip, just found
$339
Roundtrip
just found
Select avianca flight, departing Mon, Feb 9 from Cancun to Panama City, returning Mon, Feb 16, priced at $339 just found
Copa
Thu, Dec 4 - Fri, Dec 5
CUN
Cancun
PTY
Panama City
$344 Roundtrip, found 4 hours ago
$344
Roundtrip
found 4 hours ago
Select Copa flight, departing Thu, Dec 4 from Cancun to Panama City, returning Fri, Dec 5, priced at $344 found 4 hours ago
Aeromexico
Mon, Dec 15 - Fri, Dec 19
CUN
Cancun
PTY
Panama City
$346 Roundtrip, found 4 hours ago
$346
Roundtrip
found 4 hours ago
Select Aeromexico flight, departing Mon, Dec 15 from Cancun to Panama City, returning Fri, Dec 19, priced at $346 found 4 hours ago
avianca
Sat, Nov 22 - Sun, Nov 30
CUN
Cancun
PTY
Panama City
$349 Roundtrip, found 16 hours ago
$349
Roundtrip
found 16 hours ago
Select avianca flight, departing Sat, Nov 22 from Cancun to Panama City, returning Sun, Nov 30, priced at $349 found 16 hours ago
Copa
Thu, Dec 4 - Fri, Dec 5
CUN
Cancun
PTY
Panama City
$355 Roundtrip, found 4 hours ago
$355
Roundtrip
found 4 hours ago
Select Copa flight, departing Thu, Dec 4 from Cancun to Panama City, returning Fri, Dec 5, priced at $355 found 4 hours ago
American Airlines
Fri, Jan 16 - Sat, Jan 17
CUN
Cancun
PTY
Panama City
$824 Roundtrip, found 11 hours ago
$824
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Fri, Jan 16 from Cancun to Panama City, returning Sat, Jan 17, priced at $824 found 11 hours ago
United
Thu, Jan 22 - Mon, Jan 26
CUN
Cancun
PTY
Panama City
$1,259 Roundtrip, found 11 hours ago
$1,259
Roundtrip
found 11 hours ago
Select United flight, departing Thu, Jan 22 from Cancun to Panama City, returning Mon, Jan 26, priced at $1,259 found 11 hours ago

Find the cheapest month to fly from Cancun (CUN) to Panama City (PTY)

November is typically the cheapest month to fly

From $261 - $390 per traveler.

Alternative airports near Panama City

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Tocumen Intl. PTY. Cheapest option available. Average driving time to city center is 16 minutes. Flights from $320
PTY
Tocumen Intl.
Cheapest
Average driving time to city center16 min
Flights from $320

Frequently asked questions

How much does a flight from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY) cost?
Lock in a cheap one-way flight from $151 or cheap return flight from $318 from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY)?
December is the most affordable month to fly from CUN to PTY. Traveling during an off-peak travel window is often the key to finding better deals on flights.
Which airlines fly direct from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY)?
Board a nonstop flight with Copa Airlines and head straight from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY).
What is the cheapest airline that flies from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY)?
Use the filters on Expedia to compare airlines and find the most affordable carrier that'll take you from CUN to PTY. Then, sort your results by "Price (lowest to highest)" to snap up the best deal available.
How many flights per day from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY)?
Every day on average, 5 direct flights operate from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY). Select the departure date that best fits your itinerary.
What are the most popular departure times for flights from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY)?
The 11 AM departures from CUN to PTY are typically the busiest. These flights can come with a higher price due to their popularity. If you're hoping to save money, choose a less crowded time to fly.
What day of the week has the most flights from CUN to PTY?
If you depart on a Friday, you'll get the greatest range of options for flights from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY).
What is the earliest flight from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY)?
Cancun Intl. Airport (CUN)'s first flight to Tocumen Intl. Airport (PTY) takes off at approximately 7:53AM UTC-5. With a total flight time of 2h 41m, you'll arrive at around 10:34AM UTC-5.
How long does it take to fly from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY)?
The average flight time from CUN to PTY is 2 hours and 40 minutes, covering a distance of 970 mi.
What airline has the least delays from CUN to PTY?
Aeromexico has the strongest track record for on-time direct flights from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY), with an on-time rating of 97%. Use the Expedia App to view your flight status before you jet off and receive notifications about any changes.
What is the best time to fly from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY)?
Opt for a flight from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY) that leaves before 3 PM to reduce the risk of delays and cancellations. Later departures are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Panama City from Cancun Intl. Airport (CUN)?
If you're flying on a direct flight from Cancun Intl. Airport (CUN) to Panama City, Tocumen Intl. Airport (PTY) is the only airport you can land at.
Is it cheaper to buy a plane ticket from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY) last-minute?
Waiting until just before your departure to book your flight from CUN to PTY generally means paying more. While it's possible to find some last-minute offers, there's no guarantee. Keep your travel schedule open to boost your chances of landing a bargain.
Is it cheaper to book a CUN to PTY flight and hotel package?
You'll typically save money by booking a CUN to PTY flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one place. After choosing your preferred accommodations and flights, you can add extras such as tours, car rentals and activities.
Can I cancel or change the date of my flight from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY)?
In most instances, you can cancel or modify your CUN to PTY flight. However, additional charges may apply, especially if you made your booking over 24 hours ago. Double-check your itinerary for the airline's guidelines and fees on flight changes, or if you need more details, visit our Customer Service portal.

Travel information

Origin airport
Cancun Intl.
Destination airport
Tocumen Intl.
Airlines serving
Aeromexico, American Airlines, Copa, Delta, United, avianca
Roundtrip price
$318
Distance
965 mi
Average flight time
2 hours 41 mins

Book with confidence

Cancun to Panama City Flights

The cheapest times to fly from Cancun to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Cancun to Panama City are during the month of December. You can find some of the cheapest flights from Cancun to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Cancun to Panama City

Sunday is one of the best days to book for cheap flights from Cancun to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Cancun to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Cancun to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $151 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Cancun to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Cancun to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Cancun to Panama City Flights

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*Available to One Key members.