Cheap Flights from Cheyenne (CYS) to Charleston (CHS)

Popular airlines from Cheyenne, WY (CYS-Cheyenne Regional) to Charleston Intl. Airport (CHS)

  • notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
  • deals illustration

    Book smarter

    Save up to 30% on select hotels after you book a flight*
  • trophy illustration

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Cheyenne to Charleston (CYS-CHS)

Prices were available within the past 7 days and start at for one-way flights and $389 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Tue, Dec 30 - Tue, Jan 6
CYS
Cheyenne
CHS
Charleston
$389 Roundtrip, found 3 days ago
$389
Roundtrip
found 3 days ago
Select United flight, departing Tue, Dec 30 from Cheyenne to Charleston, returning Tue, Jan 6, priced at $389 found 3 days ago

Frequently asked questions

How much does a flight from Cheyenne Regional Airport (CYS) to Charleston Intl. Airport (CHS) cost?
Snag a cheap one-way flight or cheap return flight from $389 from Cheyenne Regional Airport (CYS) to Charleston Intl. Airport (CHS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Cheyenne Regional Airport (CYS) to Charleston Intl. Airport (CHS)?
The cheapest month to fly from CYS to CHS is December, when there's less demand. Off-peak months are usually when better flight deals are available between these airports.
What is the cheapest airline that flies from Cheyenne Regional Airport (CYS) to Charleston Intl. Airport (CHS)?
Expedia's filter tool lets you easily compare travel time, airlines and fares all in one place. Customize the search to your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest CYS to CHS flight.
How many flights per day from Cheyenne Regional Airport (CYS) to Charleston Intl. Airport (CHS)?
Nonstop flights from Cheyenne Regional Airport (CYS) to Charleston Intl. Airport (CHS) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your travel details and select either "1 Stop" or "2+ Stops."
What day of the week has the most flights from CYS to CHS?
Usually you'll find the most flight options available on a Friday. Tuesdays tend to be the quietest.* But this can change depending on the airline, season and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Cheyenne Regional Airport (CYS) to Charleston Intl. Airport (CHS)?
To avoid possible delays on the Cheyenne Regional Airport (CYS) to Charleston Intl. Airport (CHS) route, travel before 3 PM. Later flights have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Cheyenne Regional Airport (CYS) to Charleston Intl. Airport (CHS) last-minute?
Booking your plane ticket from CYS to CHS just before your trip is typically more expensive. However, if there's some wiggle room with your travel dates and times, you could grab a cheap last-minute fare.
Is it cheaper to book a CYS to CHS flight and hotel package?
Compared with arranging flights and hotels separately, booking a CYS to CHS flight and hotel package with Expedia could result in significant savings. What's more, having everything in one convenient place will take the stress out of planning your trip. Just pick your flights and select from our extensive range of hotels, then customize your trip with other add-ons like activities, tours and car rentals.
Can I cancel or change the date of my flight from Cheyenne Regional Airport (CYS) to Charleston Intl. Airport (CHS)?
If you booked your CYS to CHS flight within the last 24 hours, you may be able to modify or cancel it at no cost. Depending on the airline and the type of ticket you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal for more details.

Travel information

Origin airport
Cheyenne Regional
Destination airport
Charleston Intl.
Airlines serving
United
Roundtrip price
$388
Distance
1475 mi

Book with confidence

Cheyenne to Charleston Flights

The cheapest times to fly from Cheyenne to Charleston

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Cheyenne to Charleston are during the month of December. You can find some of the cheapest flights from Cheyenne to Charleston with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Cheyenne to Charleston

Sunday is one of the best days to book for cheap flights from Cheyenne to Charleston: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Cheyenne to Charleston

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Cheyenne to Charleston in 2026. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Cheyenne to Charleston flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Cheyenne to Charleston airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Cheyenne to Charleston Flights

Explore a world of travel with Expedia

*Available to One Key members.