$199 Cheap Flights from Cheyenne (CYS) to Columbus (CMH)

View $199 flight on Fri, Oct 31, 2025Opens in a new window

Popular airlines from Cheyenne, WY (CYS-Cheyenne Regional) to John Glenn Columbus Intl. Airport (CMH)

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Cheap Flights from Cheyenne to Columbus (CYS-CMH)

Prices were available within the past 7 days and start at $199 for one-way flights and $248 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Wed, Oct 22 - Wed, Oct 29
CYS
Cheyenne
CMH
Columbus
$248 Roundtrip, found 4 days ago
$248
Roundtrip
found 4 days ago
Select United flight, departing Wed, Oct 22 from Cheyenne to Columbus, returning Wed, Oct 29, priced at $248 found 4 days ago
United
Wed, Oct 22 - Wed, Oct 29
CYS
Cheyenne
CMH
Columbus
$254 Roundtrip, found 4 days ago
$254
Roundtrip
found 4 days ago
Select United flight, departing Wed, Oct 22 from Cheyenne to Columbus, returning Wed, Oct 29, priced at $254 found 4 days ago
United
Wed, Oct 22 - Wed, Oct 29
CYS
Cheyenne
CMH
Columbus
$313 Roundtrip, found 4 days ago
$313
Roundtrip
found 4 days ago
Select United flight, departing Wed, Oct 22 from Cheyenne to Columbus, returning Wed, Oct 29, priced at $313 found 4 days ago
United
Sat, Oct 4 - Sat, Oct 11
CYS
Cheyenne
CMH
Columbus
$318 Roundtrip, found 4 days ago
$318
Roundtrip
found 4 days ago
Select United flight, departing Sat, Oct 4 from Cheyenne to Columbus, returning Sat, Oct 11, priced at $318 found 4 days ago
United
Sat, Oct 4 - Sat, Oct 11
CYS
Cheyenne
CMH
Columbus
$324 Roundtrip, found 4 days ago
$324
Roundtrip
found 4 days ago
Select United flight, departing Sat, Oct 4 from Cheyenne to Columbus, returning Sat, Oct 11, priced at $324 found 4 days ago
United
Tue, Oct 21 - Wed, Oct 29
CYS
Cheyenne
CMH
Columbus
$328 Roundtrip, found 4 days ago
$328
Roundtrip
found 4 days ago
Select United flight, departing Tue, Oct 21 from Cheyenne to Columbus, returning Wed, Oct 29, priced at $328 found 4 days ago
United
Wed, Oct 22 - Wed, Oct 29
CYS
Cheyenne
CMH
Columbus
$334 Roundtrip, found 4 days ago
$334
Roundtrip
found 4 days ago
Select United flight, departing Wed, Oct 22 from Cheyenne to Columbus, returning Wed, Oct 29, priced at $334 found 4 days ago
United
Tue, Oct 7 - Tue, Oct 14
CYS
Cheyenne
CMH
Columbus
$343 Roundtrip, found 4 days ago
$343
Roundtrip
found 4 days ago
Select United flight, departing Tue, Oct 7 from Cheyenne to Columbus, returning Tue, Oct 14, priced at $343 found 4 days ago
United
Sat, Oct 4 - Sat, Oct 11
CYS
Cheyenne
CMH
Columbus
$354 Roundtrip, found 4 days ago
$354
Roundtrip
found 4 days ago
Select United flight, departing Sat, Oct 4 from Cheyenne to Columbus, returning Sat, Oct 11, priced at $354 found 4 days ago
United
Tue, Oct 7 - Sat, Oct 11
CYS
Cheyenne
CMH
Columbus
$358 Roundtrip, found 4 days ago
$358
Roundtrip
found 4 days ago
Select United flight, departing Tue, Oct 7 from Cheyenne to Columbus, returning Sat, Oct 11, priced at $358 found 4 days ago
Flights from Cheyenne (CYS) to Columbus (CMH)
Origin airport
Cheyenne Regional
Destination airport
John Glenn Columbus Intl.
Roundtrip price
$248
Distance
1150 mi

Cheyenne to Columbus Flights

The cheapest times to fly from Cheyenne to Columbus

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Cheyenne to Columbus are during the month of October. You can find some of the cheapest flights from Cheyenne to Columbus with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Cheyenne to Columbus

Sunday is one of the best days to book for cheap flights from Cheyenne to Columbus: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Cheyenne to Columbus

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Cheyenne to Columbus in 2025. You can also book with separate airlines for your outbound and return journeys, from $199 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Cheyenne to Columbus flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Cheyenne to Columbus airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Cheyenne Regional Airport (CYS) to John Glenn Columbus Intl. Airport (CMH) cost?
Secure a cheap one-way flight from $199 or cheap return flight from $248 from Cheyenne Regional Airport (CYS) to John Glenn Columbus Intl. Airport (CMH) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Cheyenne Regional Airport (CYS) to John Glenn Columbus Intl. Airport (CMH)?
October is the most affordable month to fly from CYS to CMH. Timing your trip outside of the busy season is often the key to scoring lower fares.
What is the cheapest airline that flies from Cheyenne Regional Airport (CYS) to John Glenn Columbus Intl. Airport (CMH)?
Expedia's filter tool lets you easily compare different airlines, departure times and fares all in one place. Customize the search to your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest CYS to CMH flight.
How many flights per day from Cheyenne Regional Airport (CYS) to John Glenn Columbus Intl. Airport (CMH)?
Nonstop flights from Cheyenne Regional Airport (CYS) to John Glenn Columbus Intl. Airport (CMH) aren't available daily, so you'll need to take a flight with a layover. Explore your options with our filter tool. Enter your dates and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from CYS to CMH?
Typically you'll find the largest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* But this can change depending on the time of year, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Cheyenne Regional Airport (CYS) to John Glenn Columbus Intl. Airport (CMH)?
Choose a flight from Cheyenne Regional Airport (CYS) to John Glenn Columbus Intl. Airport (CMH) that takes off before 3 PM to reduce the likelihood of delays and cancellations. Later departures are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Cheyenne Regional Airport (CYS) to John Glenn Columbus Intl. Airport (CMH) last-minute?
Waiting until just before your departure to book your flight from CYS to CMH often results in higher prices. While you may find some last-minute offers, they aren't always guaranteed. Be flexible with your itinerary to maximize your chances of landing a bargain.
Is it cheaper to book a CYS to CMH flight and hotel package?
Compared with arranging flights and hotels separately, booking a CYS to CMH flight and hotel package with Expedia could lead to significant savings. What's more, having everything in one place takes the hassle out of planning your trip. Just secure your flights and select from our extensive range of hotels, then personalize your trip with extras like tours and car rentals.
Can I cancel or change the date of my flight from Cheyenne Regional Airport (CYS) to John Glenn Columbus Intl. Airport (CMH)?
Generally, it's possible to cancel or reschedule your CYS to CMH flight. However, if it's been more than 24 hours since booking, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find further details on our Customer Service portal.

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*Available to One Key members.