$64 Cheap Flights from Des Moines (DSM) to Denver (DEN)

View $64 flight on Mon, Sep 1, 2025Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to Denver Intl. Airport (DEN)

Cheap Flights from Des Moines to Denver (DSM-DEN)

Prices were available within the past 7 days and start at $64 for one-way flights and $108 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Wed, Oct 8 - Wed, Oct 15
DSM
Des Moines
DEN
Denver
$108 Roundtrip, found 4 hours ago
$108
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Wed, Oct 8 from Des Moines to Denver, returning Wed, Oct 15, priced at $108 found 4 hours ago
Frontier Airlines
Mon, Sep 29 - Wed, Oct 8
DSM
Des Moines
DEN
Denver
$118 Roundtrip, found 3 hours ago
$118
Roundtrip
found 3 hours ago
Select Frontier Airlines flight, departing Mon, Sep 29 from Des Moines to Denver, returning Wed, Oct 8, priced at $118 found 3 hours ago
Frontier Airlines
Wed, Oct 8 - Wed, Oct 15
DSM
Des Moines
DEN
Denver
$120 Roundtrip, found 4 hours ago
$120
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Wed, Oct 8 from Des Moines to Denver, returning Wed, Oct 15, priced at $120 found 4 hours ago
Frontier Airlines
Fri, Oct 17 - Wed, Oct 22
DSM
Des Moines
DEN
Denver
$123 Roundtrip, found 8 hours ago
$123
Roundtrip
found 8 hours ago
Select Frontier Airlines flight, departing Fri, Oct 17 from Des Moines to Denver, returning Wed, Oct 22, priced at $123 found 8 hours ago
Frontier Airlines
Mon, Jul 14 - Wed, Oct 8
DSM
Des Moines
DEN
Denver
$123 Roundtrip, found 2 days ago
$123
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Mon, Jul 14 from Des Moines to Denver, returning Wed, Oct 8, priced at $123 found 2 days ago
Frontier Airlines
Thu, Aug 21 - Sun, Aug 24
DSM
Des Moines
DEN
Denver
$128 Roundtrip, found 3 hours ago
$128
Roundtrip
found 3 hours ago
Select Frontier Airlines flight, departing Thu, Aug 21 from Des Moines to Denver, returning Sun, Aug 24, priced at $128 found 3 hours ago
Frontier Airlines
Mon, Jul 14 - Fri, Jul 18
DSM
Des Moines
DEN
Denver
$130 Roundtrip, found 13 hours ago
$130
Roundtrip
found 13 hours ago
Select Frontier Airlines flight, departing Mon, Jul 14 from Des Moines to Denver, returning Fri, Jul 18, priced at $130 found 13 hours ago
Southwest Airlines
Thu, Aug 14 - Sun, Aug 24
DSM
Des Moines
DEN
Denver
$154 Roundtrip, found 1 day ago
$154
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Thu, Aug 14 from Des Moines to Denver, returning Sun, Aug 24, priced at $154 found 1 day ago
United
Thu, Oct 30 - Mon, Nov 3
DSM
Des Moines
DEN
Denver
$177 Roundtrip, just found
$177
Roundtrip
just found
Select United flight, departing Thu, Oct 30 from Des Moines to Denver, returning Mon, Nov 3, priced at $177 just found
Delta
Thu, Sep 18 - Fri, Sep 19
DSM
Des Moines
DEN
Denver
$191 Roundtrip, found 4 days ago
$191
Roundtrip
found 4 days ago
Select Delta flight, departing Thu, Sep 18 from Des Moines to Denver, returning Fri, Sep 19, priced at $191 found 4 days ago

Find the cheapest month to fly from Des Moines (DSM) to Denver (DEN)

August is typically the cheapest month to fly

From $53 - $229 per traveler.

Graph displaying average flight prices per month

Flights from Des Moines (DSM) to Denver (DEN)
Origin airport
Des Moines Intl.
Destination airport
Denver Intl.
Airlines serving
American Airlines, Delta, Frontier Airlines, Southwest Airlines, United
Roundtrip price
$108
Distance
588 mi
Average flight time
1 hour 53 mins

Des Moines to Denver Flights

The cheapest times to fly from Des Moines to Denver

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Denver are during the month of October. You can find some of the cheapest flights from Des Moines to Denver with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to Denver

Sunday is one of the best days to book for cheap flights from Des Moines to Denver: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to Denver

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Denver in 2025. You can also book with separate airlines for your outbound and return journeys, from $64 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Denver flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Denver airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to Denver Intl. Airport (DEN) cost?
Grab cheap return flights starting from $134 from Des Moines Intl. Airport (DSM) to Denver Intl. Airport (DEN). This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a Frontier Airlines flight leaving DSM on July 11 2025 and touching down at DEN. The price was last updated on June 28 2025 and has not changed since.
What is the cheapest month to fly from DSM to DEN?
The cheapest flights from DSM to DEN are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Des Moines Intl. Airport (DSM) to Denver Intl. Airport (DEN)?
You can fly straight from Des Moines Intl. Airport (DSM) to Denver Intl. Airport (DEN) on a United Airlines flight.
What is the cheapest airline that flies from DSM to DEN?
Fly from DSM to DEN with Southwest Airlines. This airline currently has the cheapest one-way ticket on this route, starting at $89. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from DSM on September 22 2025. Prices were last updated on June 28 2025 and have not changed since.
How many flights per day from Des Moines Intl. Airport (DSM) to Denver Intl. Airport (DEN)?
When departing from Des Moines Intl. Airport (DSM), you can take your pick from an average of 5 daily nonstop flights to Denver Intl. Airport (DEN).
What are the most popular departure times for flights from Des Moines Intl. Airport (DSM) to Denver Intl. Airport (DEN)?
The 5 AM departures from DSM to DEN are the most sought after. They can also be more expensive. If you're looking to save, book during off-peak hours.
What day of the week has the most flights from DSM to DEN?
Friday has the most flights from Des Moines Intl. Airport (DSM) to Denver Intl. Airport (DEN). Consider taking off on this day and you'll have a greater chance of finding a departure that fits your itinerary.
What is the earliest flight from Des Moines Intl. Airport (DSM) to Denver Intl. Airport (DEN)?
The first flight of the day departing from Des Moines Intl. Airport (DSM) is at around 5:45AM UTC-6. Catch this flight and you'll reach Denver Intl. Airport (DEN) at approximately 7:02AM UTC-7. The total flight duration is 2h 17m.
How long does it take to fly from Des Moines Intl. Airport (DSM) to Denver Intl. Airport (DEN)?
Flights from DSM to DEN have an average travel time of 2 hours and 10 minutes. The distance between the two is 590 mi.
What is the best time to fly from Des Moines Intl. Airport (DSM) to Denver Intl. Airport (DEN)?
To avoid potential delays on the Des Moines Intl. Airport (DSM) to Denver Intl. Airport (DEN) route, travel before 3 PM. Departures after this hour have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Denver from Des Moines Intl. Airport (DSM)?
If you're flying on a direct flight from Des Moines Intl. Airport (DSM) to Denver, Denver Intl. Airport (DEN) is the only airport you can touch down at.
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to Denver Intl. Airport (DEN) last-minute?
Last-minute bookings from DSM to DEN are usually more expensive. To secure the lowest rates, start searching for flights ahead of time. That being said, if you're flexible with your travel dates, it's possible to land a cheap fare just before your departure.
Is it cheaper to book a DSM to DEN flight and hotel package?
Compared with arranging flights and hotels separately, booking a DSM to DEN flight and hotel package with Expedia could result in significant savings. Better yet, having everything in one easy place will take the stress out of planning your trip. Simply pick your flights and choose from our extensive range of stays, then customize your trip with other add-ons like tours, car rentals and activities.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to Denver Intl. Airport (DEN)?
Usually, it's possible to reschedule or cancel your DSM to DEN flight. However, for bookings made more than 24 hours ago, additional fees may apply. Check your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find further details on our Customer Service portal.

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*Available to One Key members.