$566 Cheap Flights from Des Moines (DSM) to Buenos Aires (EZE)

View $566 flight on Thu, Apr 23, 2026Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to Ministro Pistarini Intl. Airport (EZE)

Cheap Flights from Des Moines to Buenos Aires (DSM-EZE)

Prices were available within the past 7 days and start at $566 for one-way flights and $1,102 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Wed, Jan 28 - Wed, Feb 11
DSM
Des Moines
EZE
Buenos Aires
$1,102 Roundtrip, found 7 hours ago
$1,102
Roundtrip
found 7 hours ago
Select Delta flight, departing Wed, Jan 28 from Des Moines to Buenos Aires, returning Wed, Feb 11, priced at $1,102 found 7 hours ago
United
Mon, Jan 19 - Tue, Feb 3
DSM
Des Moines
EZE
Buenos Aires
$1,102 Roundtrip, found 7 hours ago
$1,102
Roundtrip
found 7 hours ago
Select United flight, departing Mon, Jan 19 from Des Moines to Buenos Aires, returning Tue, Feb 3, priced at $1,102 found 7 hours ago
Delta
Wed, Jan 14 - Tue, Jan 20
DSM
Des Moines
EZE
Buenos Aires
$1,106 Roundtrip, found 2 days ago
$1,106
Roundtrip
found 2 days ago
Select Delta flight, departing Wed, Jan 14 from Des Moines to Buenos Aires, returning Tue, Jan 20, priced at $1,106 found 2 days ago
LATAM Airlines Group
Thu, Jan 15 - Wed, Jan 28
DSM
Des Moines
EZE
Buenos Aires
$1,122 Roundtrip, found 2 days ago
$1,122
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Thu, Jan 15 from Des Moines to Buenos Aires, returning Wed, Jan 28, priced at $1,122 found 2 days ago
LATAM Airlines Group
Tue, Mar 10 - Tue, Mar 17
DSM
Des Moines
EZE
Buenos Aires
$1,127 Roundtrip, found 13 hours ago
$1,127
Roundtrip
found 13 hours ago
Select LATAM Airlines Group flight, departing Tue, Mar 10 from Des Moines to Buenos Aires, returning Tue, Mar 17, priced at $1,127 found 13 hours ago
LATAM Airlines Group
Tue, Mar 10 - Tue, Mar 17
DSM
Des Moines
EZE
Buenos Aires
$1,131 Roundtrip, found 13 hours ago
$1,131
Roundtrip
found 13 hours ago
Select LATAM Airlines Group flight, departing Tue, Mar 10 from Des Moines to Buenos Aires, returning Tue, Mar 17, priced at $1,131 found 13 hours ago
LATAM Airlines Group
Tue, Mar 10 - Tue, Mar 17
DSM
Des Moines
EZE
Buenos Aires
$1,136 Roundtrip, found 13 hours ago
$1,136
Roundtrip
found 13 hours ago
Select LATAM Airlines Group flight, departing Tue, Mar 10 from Des Moines to Buenos Aires, returning Tue, Mar 17, priced at $1,136 found 13 hours ago
LATAM Airlines Group
Wed, Mar 4 - Wed, Mar 18
DSM
Des Moines
EZE
Buenos Aires
$1,140 Roundtrip, found 4 days ago
$1,140
Roundtrip
found 4 days ago
Select LATAM Airlines Group flight, departing Wed, Mar 4 from Des Moines to Buenos Aires, returning Wed, Mar 18, priced at $1,140 found 4 days ago
American Airlines
Sat, Jan 24 - Thu, Jan 29
DSM
Des Moines
EZE
Buenos Aires
$1,186 Roundtrip, found 5 days ago
$1,186
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sat, Jan 24 from Des Moines to Buenos Aires, returning Thu, Jan 29, priced at $1,186 found 5 days ago
Air Canada
Sat, Mar 21 - Wed, Mar 25
DSM
Des Moines
EZE
Buenos Aires
$1,577 Roundtrip, found 1 day ago
$1,577
Roundtrip
found 1 day ago
Select Air Canada flight, departing Sat, Mar 21 from Des Moines to Buenos Aires, returning Wed, Mar 25, priced at $1,577 found 1 day ago

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Alternative airports near Buenos Aires

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Aeroparque Jorge Newbery AEP. Closest option available. Average driving time to city center is 11 minutes. Flights from $6,241
AEP
Aeroparque Jorge Newbery
Closest
Average driving time to city center11 min
Flights from $6,241
Flights from Des Moines (DSM) to Buenos Aires (EZE)
Origin airport
Des Moines Intl.
Destination airport
Ministro Pistarini Intl.
Airlines serving
Air Canada, American Airlines, Copa, Delta, LATAM Airlines Group, United
Roundtrip price
$1,101
Distance
5724 mi

Des Moines to Buenos Aires Flights

The cheapest times to fly from Des Moines to Buenos Aires

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Buenos Aires are during the month of January. You can find some of the cheapest flights from Des Moines to Buenos Aires with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to Buenos Aires

Sunday is one of the best days to book for cheap flights from Des Moines to Buenos Aires: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to Buenos Aires

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Buenos Aires in 2025. You can also book with separate airlines for your outbound and return journeys, from $566 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Buenos Aires flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Buenos Aires airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to Ministro Pistarini Intl. Airport (EZE) cost?
Lock in a cheap one-way flight from $566 or cheap return flight from $1,102 from Des Moines Intl. Airport (DSM) to Ministro Pistarini Intl. Airport (EZE) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Des Moines Intl. Airport (DSM) to Ministro Pistarini Intl. Airport (EZE)?
Traveling in January may help you find better deals, as it's the cheapest month for flights between DSM and EZE. You'll typically find the lowest prices during the off-season.
What is the cheapest airline that flies from Des Moines Intl. Airport (DSM) to Ministro Pistarini Intl. Airport (EZE)?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from DSM to EZE. Then, sort your results by "Price (lowest to highest)" to score a good deal.
How many flights per day from Des Moines Intl. Airport (DSM) to Ministro Pistarini Intl. Airport (EZE)?
You'll need to hop on a flight with a layover if you're traveling from Des Moines Intl. Airport (DSM) to Ministro Pistarini Intl. Airport (EZE). There are no daily direct flights on this route. However, just filter your search to include one or two stops to find the best option for your trip.
What day of the week has the most flights from DSM to EZE?
Friday is generally the busiest day for flights, while Tuesday is often the quietest.* Remember that flight schedules can change based on a range of factors, such as the season and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Des Moines Intl. Airport (DSM) to Ministro Pistarini Intl. Airport (EZE)?
Book a flight from Des Moines Intl. Airport (DSM) to Ministro Pistarini Intl. Airport (EZE) that takes off before 3 PM to reduce the risk of cancellations. Departures after this time are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to Ministro Pistarini Intl. Airport (EZE) last-minute?
Booking your plane ticket from DSM to EZE just before your getaway is generally more expensive. But if you're flexible with your itinerary, you could land a cheap last-minute fare.
Is it cheaper to book a DSM to EZE flight and hotel package?
Compared with arranging hotels and flights separately, booking a DSM to EZE flight and hotel package with Expedia could lead to significant savings. Better yet, managing everything in one place will take the stress out of travel planning. Just pick your flights and select from our wide range of hotels, then customize your trip with extras like tours, activities and car rentals.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to Ministro Pistarini Intl. Airport (EZE)?
It's usually possible to cancel or reschedule your DSM to EZE flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find further details on our Customer Service portal.

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*Available to One Key members.