$234 Cheap Flights from Panama City (ECP) to Santa Fe (SAF)

View $234 flight on Wed, Mar 11, 2026Opens in a new window

Popular airlines from Northwest Florida Beaches Intl. Airport (ECP) to Santa Fe Municipal Airport (SAF)

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Cheap Flights from Panama City to Santa Fe (ECP-SAF)

Prices were available within the past 7 days and start at $234 for one-way flights and $394 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Mar 11 - Tue, Mar 24
ECP
Panama City
SAF
Santa Fe
$394 Roundtrip, found 19 hours ago
$394
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Wed, Mar 11 from Panama City to Santa Fe, returning Tue, Mar 24, priced at $394 found 19 hours ago
American Airlines
Tue, Mar 10 - Tue, Mar 24
ECP
Panama City
SAF
Santa Fe
$435 Roundtrip, found 19 hours ago
$435
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Tue, Mar 10 from Panama City to Santa Fe, returning Tue, Mar 24, priced at $435 found 19 hours ago
American Airlines
Wed, Mar 11 - Sat, Mar 21
ECP
Panama City
SAF
Santa Fe
$466 Roundtrip, found 19 hours ago
$466
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Wed, Mar 11 from Panama City to Santa Fe, returning Sat, Mar 21, priced at $466 found 19 hours ago
American Airlines
Thu, Mar 12 - Tue, Mar 24
ECP
Panama City
SAF
Santa Fe
$483 Roundtrip, found 19 hours ago
$483
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Thu, Mar 12 from Panama City to Santa Fe, returning Tue, Mar 24, priced at $483 found 19 hours ago
United
Tue, Mar 10 - Sat, Mar 21
ECP
Panama City
SAF
Santa Fe
$498 Roundtrip, found 19 hours ago
$498
Roundtrip
found 19 hours ago
Select United flight, departing Tue, Mar 10 from Panama City to Santa Fe, returning Sat, Mar 21, priced at $498 found 19 hours ago
American Airlines
Wed, Mar 11 - Sat, Mar 21
ECP
Panama City
SAF
Santa Fe
$507 Roundtrip, found 19 hours ago
$507
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Wed, Mar 11 from Panama City to Santa Fe, returning Sat, Mar 21, priced at $507 found 19 hours ago
American Airlines
Wed, Mar 11 - Sat, Mar 21
ECP
Panama City
SAF
Santa Fe
$528 Roundtrip, found 19 hours ago
$528
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Wed, Mar 11 from Panama City to Santa Fe, returning Sat, Mar 21, priced at $528 found 19 hours ago
American Airlines
Mon, Mar 9 - Tue, Mar 24
ECP
Panama City
SAF
Santa Fe
$532 Roundtrip, found 19 hours ago
$532
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Mon, Mar 9 from Panama City to Santa Fe, returning Tue, Mar 24, priced at $532 found 19 hours ago
American Airlines
Wed, Mar 11 - Mon, Mar 23
ECP
Panama City
SAF
Santa Fe
$533 Roundtrip, found 19 hours ago
$533
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Wed, Mar 11 from Panama City to Santa Fe, returning Mon, Mar 23, priced at $533 found 19 hours ago
American Airlines
Wed, Mar 11 - Wed, Mar 18
ECP
Panama City
SAF
Santa Fe
$541 Roundtrip, found 19 hours ago
$541
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Wed, Mar 11 from Panama City to Santa Fe, returning Wed, Mar 18, priced at $541 found 19 hours ago

Frequently asked questions

How much does a flight from Northwest Florida Beaches Intl. Airport (ECP) to Santa Fe Municipal Airport (SAF) cost?
Get a cheap one-way flight from $234 or cheap return flight from $394 from Northwest Florida Beaches Intl. Airport (ECP) to Santa Fe Municipal Airport (SAF) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Northwest Florida Beaches Intl. Airport (ECP) to Santa Fe Municipal Airport (SAF)?
Planning your getaway for March is a great way to save, as it's the cheapest month for flights between ECP and SAF. You'll often find the lowest prices during off-peak months.
What is the cheapest airline that flies from Northwest Florida Beaches Intl. Airport (ECP) to Santa Fe Municipal Airport (SAF)?
Expedia's filter tool lets you easily compare airlines, flight times and baggage options all in one place. Tailor the search to your trip, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest ECP to SAF flight.
How many flights per day from Northwest Florida Beaches Intl. Airport (ECP) to Santa Fe Municipal Airport (SAF)?
There are no daily direct flights available from Northwest Florida Beaches Intl. Airport (ECP) to Santa Fe Municipal Airport (SAF). But you can book flights with layovers. Filter your search on Expedia to include one or more stops, and you'll be soaring above the clouds in no time at all.
What day of the week has the most flights from ECP to SAF?
You'll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Northwest Florida Beaches Intl. Airport (ECP) to Santa Fe Municipal Airport (SAF)?
Opt for a flight from Northwest Florida Beaches Intl. Airport (ECP) to Santa Fe Municipal Airport (SAF) that leaves before 3 PM to reduce the risk of delays and cancellations. Departures after this time are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Northwest Florida Beaches Intl. Airport (ECP) to Santa Fe Municipal Airport (SAF) last-minute?
Last-minute fares from ECP to SAF are usually more expensive. To secure the lowest prices, start searching for flights well in advance. That said, if you're flexible with your travel plans, it's possible to find a cheap ticket right before you leave.
Is it cheaper to book an ECP to SAF flight and hotel package?
Booking an ECP to SAF flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip in one place. Select from our impressive range of stays and then add car rentals, flights and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Northwest Florida Beaches Intl. Airport (ECP) to Santa Fe Municipal Airport (SAF)?
Typically, it's possible to reschedule or cancel your ECP to SAF flight. However, if the booking was made more than 24 hours ago, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find further details on our Customer Service portal.

Travel information

Travel information

Origin airport
Northwest Florida Beaches Intl.
Destination airport
Santa Fe Municipal
Airlines serving
American Airlines, United
Roundtrip price
$394
Distance
1227 mi

Book with confidence

Book with confidence

Panama City to Santa Fe Flights

The cheapest times to fly from Panama City to Santa Fe

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to Santa Fe are during the month of March. You can find some of the cheapest flights from Panama City to Santa Fe with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Panama City to Santa Fe

Sunday is one of the best days to book for cheap flights from Panama City to Santa Fe: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Panama City to Santa Fe

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to Santa Fe in 2025. You can also book with separate airlines for your outbound and return journeys, from $234 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to Santa Fe flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Panama City to Santa Fe airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Panama City to Santa Fe Flights

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Explore a world of travel with Expedia

*Available to One Key members.